AR069249A1 - Derivado de indazol, activo en el dolor neuropatico - Google Patents
Derivado de indazol, activo en el dolor neuropaticoInfo
- Publication number
- AR069249A1 AR069249A1 ARP080104907A ARP080104907A AR069249A1 AR 069249 A1 AR069249 A1 AR 069249A1 AR P080104907 A ARP080104907 A AR P080104907A AR P080104907 A ARP080104907 A AR P080104907A AR 069249 A1 AR069249 A1 AR 069249A1
- Authority
- AR
- Argentina
- Prior art keywords
- active
- neuropathic pain
- relates
- indazol
- derived
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Rheumatology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicinal Preparation (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
La presente invencion se refiere a un compuesto de formula (1): en la que: R es un grupo alquilo lineal o ramificado que contiene entre 1 y 3 átomos de carbono, Y es CH o N, y p es un numero entero entre 0 y 3, y sales del mismo, o bien sales de adicion de ácido con un ácido mineral u orgánico farmacéuticamente aceptable o bien sales de adicion de base con una base mineral u orgánica farmacéuticamente aceptable. La invencion también se refiere a un procedimiento para preparar el compuesto de formula (1) y a una composicion farmacéutica que lo comprende. La invencion también se refiere a la utilizacion de un indazol para preparar una composicion farmacéutica que es activa en el tratamiento del dolor neuropático.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP07425709 | 2007-11-12 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR069249A1 true AR069249A1 (es) | 2010-01-06 |
Family
ID=39312937
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP080104907A AR069249A1 (es) | 2007-11-12 | 2008-11-10 | Derivado de indazol, activo en el dolor neuropatico |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US8455519B2 (es) |
| EP (1) | EP2207776B9 (es) |
| JP (1) | JP5443372B2 (es) |
| KR (1) | KR101555626B1 (es) |
| CN (1) | CN101855220B (es) |
| AR (1) | AR069249A1 (es) |
| AU (1) | AU2008323026B2 (es) |
| CA (1) | CA2702874C (es) |
| CY (1) | CY1118131T1 (es) |
| DK (1) | DK2207776T3 (es) |
| EA (1) | EA019405B1 (es) |
| ES (1) | ES2601250T3 (es) |
| GE (1) | GEP20125526B (es) |
| HK (1) | HK1142884A1 (es) |
| HR (1) | HRP20161497T1 (es) |
| HU (1) | HUE031676T2 (es) |
| IL (1) | IL205309A (es) |
| LT (1) | LT2207776T (es) |
| MX (1) | MX2010005267A (es) |
| PL (1) | PL2207776T3 (es) |
| PT (1) | PT2207776T (es) |
| SG (1) | SG185982A1 (es) |
| SI (1) | SI2207776T1 (es) |
| UA (1) | UA99927C2 (es) |
| WO (1) | WO2009062883A1 (es) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20140130124A (ko) | 2012-02-21 | 2014-11-07 | 아지엔드 키미쉐 리유나이트 안젤리니 프란체스코 에이.씨.알.에이.에프. 에스.피.에이 | 글리코겐 합성효소 키나아제 3 베타 억제제로서 1h-인다졸-3-카복사미드 화합물 |
| SG11201403788VA (en) | 2012-02-21 | 2014-08-28 | Acraf | Use of 1h-indazole-3-carboxamide compounds as glycogen synthase kinase 3 beta inhibitors |
| EP3831810A4 (en) * | 2018-07-31 | 2022-04-20 | ONO Pharmaceutical Co., Ltd. | BENZENE DERIVATIVE |
| JP7384179B2 (ja) * | 2020-01-29 | 2023-11-21 | 小野薬品工業株式会社 | ベンゼン誘導体を含有する医薬組成物 |
| JPWO2021153690A1 (es) * | 2020-01-29 | 2021-08-05 | ||
| WO2022097764A1 (ko) | 2020-11-04 | 2022-05-12 | 전남대학교병원 | 프레가발린 및 티아넵틴을 포함하는 신경병성 통증 치료용 약학적 조성물 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5945434A (en) * | 1995-05-31 | 1999-08-31 | Nisshin Flour Milling Co., Ltd. | Indazole derivatives having monocyclic amine |
| IT1291569B1 (it) * | 1997-04-15 | 1999-01-11 | Angelini Ricerche Spa | Indazolammidi come agenti serotoninergici |
| EP1182193A4 (en) * | 1999-04-09 | 2002-09-11 | Mochida Pharm Co Ltd | REMEDIES FOR NEUROGENIC PAIN |
| ITMI20030972A1 (it) * | 2003-05-15 | 2004-11-16 | Acraf | Indazolo dotato di attivita' analgesica, metodo per prepararlo e composizione farmaceutica che lo comprende. |
| ITMI20031468A1 (it) * | 2003-07-18 | 2005-01-19 | Acraf | Farmaco ativo nel dolore neuropatico |
| DE602004025508D1 (de) * | 2003-12-23 | 2010-03-25 | Serodus As | Modulatoren von peripheren 5-ht-rezeptoren |
-
2008
- 2008-06-11 UA UAA201004709A patent/UA99927C2/uk unknown
- 2008-11-06 CA CA2702874A patent/CA2702874C/en not_active Expired - Fee Related
- 2008-11-06 MX MX2010005267A patent/MX2010005267A/es active IP Right Grant
- 2008-11-06 KR KR1020107011237A patent/KR101555626B1/ko not_active IP Right Cessation
- 2008-11-06 EA EA201070603A patent/EA019405B1/ru not_active IP Right Cessation
- 2008-11-06 SG SG2012082947A patent/SG185982A1/en unknown
- 2008-11-06 HU HUE08850378A patent/HUE031676T2/en unknown
- 2008-11-06 ES ES08850378.4T patent/ES2601250T3/es active Active
- 2008-11-06 GE GEAP200811841A patent/GEP20125526B/en unknown
- 2008-11-06 US US12/738,499 patent/US8455519B2/en not_active Expired - Fee Related
- 2008-11-06 SI SI200831689A patent/SI2207776T1/sl unknown
- 2008-11-06 EP EP08850378.4A patent/EP2207776B9/en active Active
- 2008-11-06 JP JP2010532593A patent/JP5443372B2/ja not_active Expired - Fee Related
- 2008-11-06 PT PT88503784T patent/PT2207776T/pt unknown
- 2008-11-06 CN CN200880115527.1A patent/CN101855220B/zh not_active Expired - Fee Related
- 2008-11-06 PL PL08850378T patent/PL2207776T3/pl unknown
- 2008-11-06 WO PCT/EP2008/065081 patent/WO2009062883A1/en active Application Filing
- 2008-11-06 LT LTEP08850378.4T patent/LT2207776T/lt unknown
- 2008-11-06 AU AU2008323026A patent/AU2008323026B2/en not_active Ceased
- 2008-11-06 DK DK08850378.4T patent/DK2207776T3/en active
- 2008-11-10 AR ARP080104907A patent/AR069249A1/es unknown
-
2010
- 2010-04-25 IL IL205309A patent/IL205309A/en not_active IP Right Cessation
- 2010-09-14 HK HK10108732.4A patent/HK1142884A1/zh not_active IP Right Cessation
-
2016
- 2016-10-21 CY CY20161101061T patent/CY1118131T1/el unknown
- 2016-11-14 HR HRP20161497TT patent/HRP20161497T1/hr unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AR069249A1 (es) | Derivado de indazol, activo en el dolor neuropatico | |
| UY31046A1 (es) | Derivados sustituidos de n-(3,4-dihidro-2h-cromen-3-il)formamida y n-(1, 2,3 ,4-tetrahidronaftalen-2-il)formamida, sales de los mismos, composiciones que los contienen, procedimientos para su preparacion y aplicaciones | |
| MX2021006421A (es) | Anilidas de aminoácidos como moduladores de moléculas pequeñas de interleucinas-17 (il-17). | |
| BR112014025564A2 (pt) | composto heterocíclico contendo nitrogênio ou sal do mesmo | |
| UY30438A1 (es) | Derivados n-sustituidos de 5-halo-4-[2-alquil-1-sustituidos-1h-imidazol-5-il]pirimidin-2-amina, composiciones-procesos para su preparacion y usos | |
| CO6690768A2 (es) | Derivados de triazina-oxadiazoles, útiles como inhibidores de los canales de sodio navi.7 | |
| SV2006002103A (es) | Compuestos de aril- o heteroarilamida ortosustituidos ref. pc32242a | |
| RU2011139107A (ru) | Специфические соединения диарилгидантоина и диарилтиогидантоина | |
| HN2011000699A (es) | El compuesto (s)-1-({4-metil-5-[2-(2,2,2-trifluoro-1,1-dimetil-etil)-piridin-4-il]-tiazol-2-il}-amida) de 2-amida del acido pirrolidin-1,2-dicarboxilico en forma libre o de sal y composiciones y composicion farmaceutica que lo contiene. | |
| UY30440A1 (es) | Nuevos compuestos | |
| ATE442349T1 (de) | Diacylglycerol-acyltransferase-hemmer | |
| NO20091620L (no) | Boronsyre og estere som inhibitorer av fettsyreamidhydrolaser | |
| UY29410A1 (es) | Composiciones farmacéuticas en base a metilamidas del ácido 4-(4-/-3(-4-cloro-3-trifluorometifenil)ureido)fenoxi)piridin-2-carboxílico, procedimiento de preparación y aplicaciones. | |
| CY1117449T1 (el) | Φαινυλιουχα ν-ακυλο παραγωγα αμινων και αμινοξεων, μεθοδοι για την παραγωγη αυτων, μια φαρμακευτικη συνθεση και η χρηση αυτων | |
| MX2012005689A (es) | Analogos de acido araquidonico y metodos para el tratamiento analgesico utilizando los mismos. | |
| PH12015502802A1 (en) | Formulation comprising a hypolipidemic agent | |
| CY1115623T1 (el) | Μεθοδος για την συνθεση 7,8-διμεθοξυ-1,3-διϋδρο-2η-3-βενζαζεπιν-2-ονης και εφαρμογη αυτης στη συνθεση της ιβαμπραδινης καθως επισης αλατων προσθηκης αυτης με ενα φαρμακευτικως αποδεκτο οξυ | |
| EA201491994A1 (ru) | Способы комплексообразования с циклодекстринами для введения пептидных протеасомных ингибиторов в фармацевтические составы | |
| CO6351721A2 (es) | Uso de dronedarona para la preparacion de un medicamento para la prevencion de ictus o ataque isquemico transitorio | |
| AR062737A1 (es) | Composicion farmaceutica que comprende un compuesto derivado de aril-azabiciclo, compuesto correspondiente y su uso para la preparacion de un medicamento | |
| NO20084478L (no) | Konjugerte lipidderivater | |
| MX2022015554A (es) | Moduladores de molecula peque?a de interleucina 17 (il-17). | |
| UA87284C2 (ru) | Соединения фенилпиридилпиперазина, способ их получения и фармацевтическая композиция, которая их содержит | |
| MA32062B1 (fr) | Sels de triazolium comme inhibiteurs de par1, leur production et leur utilisation comme médicaments | |
| ECSP10010421A (es) | Procedimiento de preparación de combretastatina |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |