CO6351721A2 - Uso de dronedarona para la preparacion de un medicamento para la prevencion de ictus o ataque isquemico transitorio - Google Patents
Uso de dronedarona para la preparacion de un medicamento para la prevencion de ictus o ataque isquemico transitorioInfo
- Publication number
- CO6351721A2 CO6351721A2 CO11013463A CO11013463A CO6351721A2 CO 6351721 A2 CO6351721 A2 CO 6351721A2 CO 11013463 A CO11013463 A CO 11013463A CO 11013463 A CO11013463 A CO 11013463A CO 6351721 A2 CO6351721 A2 CO 6351721A2
- Authority
- CO
- Colombia
- Prior art keywords
- dronedarone
- prevention
- attack
- ictus
- ischemical
- Prior art date
Links
- ZQTNQVWKHCQYLQ-UHFFFAOYSA-N dronedarone Chemical compound C1=CC(OCCCN(CCCC)CCCC)=CC=C1C(=O)C1=C(CCCC)OC2=CC=C(NS(C)(=O)=O)C=C12 ZQTNQVWKHCQYLQ-UHFFFAOYSA-N 0.000 title abstract 2
- 229960002084 dronedarone Drugs 0.000 title abstract 2
- 229940126601 medicinal product Drugs 0.000 title 1
- 230000002265 prevention Effects 0.000 title 1
- 150000003839 salts Chemical class 0.000 abstract 3
- 239000008194 pharmaceutical composition Substances 0.000 abstract 2
- 208000032109 Transient ischaemic attack Diseases 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
- 230000009861 stroke prevention Effects 0.000 abstract 1
- 201000010875 transient cerebral ischemia Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
- A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers with substantial amounts of non-phosphatidyl, i.e. non-acylglycerophosphate, surfactants as bilayer-forming substances, e.g. cationic lipids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1277—Processes for preparing; Proliposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
Abstract
La presente invención se refiere a una composición farmacéutica que comprende como principio activo dronedarona o una de sus sales farmacéuticamente aceptables. Esta composición farmacéutica comprende una dosis eficaz de al menos un compuesto de fórmula (I), o una sal de adición de éste con una sal farmacéuticamente aceptable, o un hidrato o solvato de este, y al menos un excipiente farmacéuticamente aceptable y uso para la prevención de ictus o ataque isquémico transitorio.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP08290761A EP2153830A1 (en) | 2008-08-07 | 2008-08-07 | Use of dronedarone for the preparation of a medicament intended for the prevention of stroke or transient ischemic attack |
US8780308P | 2008-08-11 | 2008-08-11 |
Publications (1)
Publication Number | Publication Date |
---|---|
CO6351721A2 true CO6351721A2 (es) | 2011-12-20 |
Family
ID=40149599
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CO11013463A CO6351721A2 (es) | 2008-08-07 | 2011-02-07 | Uso de dronedarona para la preparacion de un medicamento para la prevencion de ictus o ataque isquemico transitorio |
Country Status (24)
Country | Link |
---|---|
US (1) | US20110230552A1 (es) |
EP (2) | EP2153830A1 (es) |
JP (1) | JP2011529958A (es) |
KR (1) | KR20110042344A (es) |
CN (1) | CN102149377A (es) |
AR (1) | AR073265A1 (es) |
AU (1) | AU2009278864A1 (es) |
BR (1) | BRPI0917569A2 (es) |
CA (1) | CA2733149A1 (es) |
CL (1) | CL2011000268A1 (es) |
CO (1) | CO6351721A2 (es) |
CR (1) | CR20110061A (es) |
DO (1) | DOP2011000043A (es) |
EA (1) | EA201170301A1 (es) |
EC (1) | ECSP11010811A (es) |
IL (1) | IL211098A0 (es) |
MA (1) | MA32602B1 (es) |
MX (1) | MX2011001461A (es) |
NI (1) | NI201100034A (es) |
PE (1) | PE20110706A1 (es) |
SV (1) | SV2011003827A (es) |
TW (1) | TW201010695A (es) |
UY (1) | UY32040A (es) |
WO (1) | WO2010015939A1 (es) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2930149B1 (fr) * | 2008-04-17 | 2011-02-18 | Sanofi Aventis | Association de dronedarone avec au moins un diuretique, son application en therapeutique |
EP2684564A1 (en) * | 2008-04-17 | 2014-01-15 | Sanofi | Use of dronedarone for the preparation of a medicament for use in the prevention of cardiovascular hospitalization or in the prevention of atrial fibrillation |
EP2116239A1 (en) * | 2008-04-29 | 2009-11-11 | Sanofi-Aventis | Method for managing the risks associated with an increase in serum creatinine during dronedarone treatment |
EP2387996A1 (en) * | 2010-05-17 | 2011-11-23 | Sanofi | Use of dronedarone for the preparation of a medicament for the prevention of cardiovascular events in patients with permanent atrial fibrillation |
EP2387997A1 (en) * | 2010-05-18 | 2011-11-23 | Sanofi | Use of dronedarone for the preparation of a medicament for the prevention of cardiovascular events in patients who developed permanent atrial fibrillation throughout the period the dronedarone is administered |
WO2011141888A1 (en) * | 2010-05-13 | 2011-11-17 | Sanofi | Use of dronedarone for the preparation of a medicament for the prevention of cardiovacular hospitalizations or death or cardiovascular events in patients with permanent atrial fibrillation |
US8602215B2 (en) | 2010-06-30 | 2013-12-10 | Sanofi | Methods for reducing the risk of an adverse dronedarone/beta-blockers interaction in a patient suffering from atrial fibrillation |
WO2013024411A1 (en) | 2011-08-12 | 2013-02-21 | Lupin Limited | Co-milled formulation of dronedarone |
US10603316B2 (en) | 2013-08-21 | 2020-03-31 | Morehouse School Of Medicine | Composition and methods for preventing or reducing the incidence of transient ischemic attacks |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9009389D0 (en) * | 1990-04-26 | 1990-06-20 | Smith Kline French Lab | Treatment |
FR2665444B1 (fr) | 1990-08-06 | 1992-11-27 | Sanofi Sa | Derives d'amino-benzofuranne, benzothiophene ou indole, leur procede de preparation ainsi que les compositions les contenant. |
-
2008
- 2008-08-07 EP EP08290761A patent/EP2153830A1/en not_active Withdrawn
-
2009
- 2009-08-03 JP JP2011521656A patent/JP2011529958A/ja not_active Withdrawn
- 2009-08-03 CA CA2733149A patent/CA2733149A1/en not_active Abandoned
- 2009-08-03 PE PE2011000135A patent/PE20110706A1/es not_active Application Discontinuation
- 2009-08-03 MX MX2011001461A patent/MX2011001461A/es not_active Application Discontinuation
- 2009-08-03 EA EA201170301A patent/EA201170301A1/ru unknown
- 2009-08-03 WO PCT/IB2009/006831 patent/WO2010015939A1/en active Application Filing
- 2009-08-03 AU AU2009278864A patent/AU2009278864A1/en not_active Abandoned
- 2009-08-03 BR BRPI0917569A patent/BRPI0917569A2/pt not_active IP Right Cessation
- 2009-08-03 CN CN200980135272XA patent/CN102149377A/zh active Pending
- 2009-08-03 EP EP09786247A patent/EP2326324A1/en not_active Withdrawn
- 2009-08-03 KR KR1020117005222A patent/KR20110042344A/ko not_active Application Discontinuation
- 2009-08-06 TW TW098126633A patent/TW201010695A/zh unknown
- 2009-08-06 AR ARP090103009A patent/AR073265A1/es unknown
- 2009-08-07 UY UY0001032040A patent/UY32040A/es not_active Application Discontinuation
-
2011
- 2011-02-02 CR CR20110061A patent/CR20110061A/es not_active Application Discontinuation
- 2011-02-03 DO DO2011000043A patent/DOP2011000043A/es unknown
- 2011-02-04 SV SV2011003827A patent/SV2011003827A/es unknown
- 2011-02-04 EC EC2011010811A patent/ECSP11010811A/es unknown
- 2011-02-04 US US13/020,889 patent/US20110230552A1/en not_active Abandoned
- 2011-02-06 IL IL211098A patent/IL211098A0/en unknown
- 2011-02-07 CL CL2011000268A patent/CL2011000268A1/es unknown
- 2011-02-07 NI NI201100034A patent/NI201100034A/es unknown
- 2011-02-07 CO CO11013463A patent/CO6351721A2/es not_active Application Discontinuation
- 2011-03-01 MA MA33659A patent/MA32602B1/fr unknown
Also Published As
Publication number | Publication date |
---|---|
EA201170301A1 (ru) | 2012-01-30 |
TW201010695A (en) | 2010-03-16 |
BRPI0917569A2 (pt) | 2019-09-24 |
EP2326324A1 (en) | 2011-06-01 |
IL211098A0 (en) | 2011-04-28 |
WO2010015939A1 (en) | 2010-02-11 |
UY32040A (es) | 2010-03-26 |
AU2009278864A1 (en) | 2010-02-11 |
EP2153830A1 (en) | 2010-02-17 |
CL2011000268A1 (es) | 2011-07-29 |
SV2011003827A (es) | 2011-04-29 |
NI201100034A (es) | 2011-10-20 |
DOP2011000043A (es) | 2011-03-15 |
AR073265A1 (es) | 2010-10-28 |
MX2011001461A (es) | 2011-03-29 |
ECSP11010811A (es) | 2011-03-31 |
CA2733149A1 (en) | 2010-02-11 |
JP2011529958A (ja) | 2011-12-15 |
US20110230552A1 (en) | 2011-09-22 |
KR20110042344A (ko) | 2011-04-26 |
CR20110061A (es) | 2011-04-04 |
CN102149377A (zh) | 2011-08-10 |
PE20110706A1 (es) | 2011-10-11 |
MA32602B1 (fr) | 2011-09-01 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CO6351721A2 (es) | Uso de dronedarona para la preparacion de un medicamento para la prevencion de ictus o ataque isquemico transitorio | |
CY1118292T1 (el) | Ρυθμιστες φαρμακοκινητικων ιδιοτητων των θεραπευτικων | |
CY1118915T1 (el) | Αντιβακτηριακα αναλογα αμινογλυκοσιδης | |
UA109421C2 (uk) | Фармацевтична композиція, яка містить ліганди сигма-рецептора | |
AR053162A1 (es) | Compuesto 5 - oxo - pirrolidin sustituido, composicion farmaceutica que lo comprende y su uso para preparar un medicamento para el tratamiento del glaucoma. | |
UY32816A (es) | Formulación farmacéutica a base de 1-[2-(2,1,3-benzotiadiazol-5-ilamino)-6(2,6-diclorofenil)-pirido[2,3-d] pirimidin-7-il]-3-tert-butil-uréa | |
CL2011000589A1 (es) | Compuestos derivados de pirrolidin-2-carboxamida, inhibidores de la interaccion p53-mdm2; composicion farmaceutica que los comprende; y su uso en la preparacion de medicamentos utiles para el tratamiento del cancer. | |
UY33183A (es) | Compuestos inhibidores de virus flaviviridae, composición farmaceutica que los contiene y su uso en la manufactura de un medicamento | |
UY33075A (es) | Derivados de ciclohexano y usos de los mismos | |
UY32315A (es) | Compuestos de piperidina y usos de los mismo-596 | |
AR080491A1 (es) | Formulaciones orales y sales lipofilicas de metilnaltrexona | |
BR112012013252A2 (pt) | composição farmacêutica tópica, preservativo, composto, e, uso do mesmo | |
ECSP13012812A (es) | Formulaciones inmunosupresoras | |
CO6321158A2 (es) | Formulacion oral | |
BR112013026361A2 (pt) | derivados de glicosídeo e usos dos mesmos | |
ES2531312T3 (es) | Formulaciones, sales y polimorfos de transnorsertralina y usos de los mismos | |
UY30847A1 (es) | Uso de derivados de mononitrato de dianhidrohexita como agentes para el tratamiento de trastornos intestinales | |
UY32316A (es) | Derivados de piperidina utiles en el tratamiento de infecciones bacterianas | |
UY33745A (es) | Derivados de difenilamina: usos, procedimiento de síntesis y composiciones farmacéuticas | |
UY29403A1 (es) | Composiciones farmacéutica sólida que comprende telitromicina. | |
CL2012001641A1 (es) | Compuestos derivados de piperazina; composición farmacéutica; que comprende a uno de los compuestos y uso de los compuestos en la preparación de medicamentos para el tratamiento y/o prevención de infecciones por protozoos, en forma particular para el tratamiento y/o prevención de la malaria. | |
BR112012024346A2 (pt) | agente terapêutico ou agente profilático para a doença de alzheimer | |
AR089710A1 (es) | Composiciones farmaceuticas estabilizadas de un inhibidor del virus de hepatitis c | |
TR200802061A2 (tr) | Yüksek oranda aktif madde içeren farmasötlk formülasyon. | |
AR095957A2 (es) | Un compuesto derivado de piperidinilo, composición farmaceutica que lo comprende y sus usos para la preparación de un medicamento |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC | Application refused |