AR066472A1 - Compuesto de triazolil aminopirimidina, composicion farmaceutica que lo comprende y su uso para preparar un medicamento - Google Patents
Compuesto de triazolil aminopirimidina, composicion farmaceutica que lo comprende y su uso para preparar un medicamentoInfo
- Publication number
- AR066472A1 AR066472A1 ARP080101931A ARP080101931A AR066472A1 AR 066472 A1 AR066472 A1 AR 066472A1 AR P080101931 A ARP080101931 A AR P080101931A AR P080101931 A ARP080101931 A AR P080101931A AR 066472 A1 AR066472 A1 AR 066472A1
- Authority
- AR
- Argentina
- Prior art keywords
- methyl
- amino
- alkyl
- hydroxy
- hydrogen
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 239000002131 composite material Substances 0.000 title 1
- 229940126601 medicinal product Drugs 0.000 title 1
- -1 triazolyl aminopyrimidine compound Chemical class 0.000 abstract 15
- 229910052739 hydrogen Inorganic materials 0.000 abstract 6
- 239000001257 hydrogen Substances 0.000 abstract 6
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 6
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 6
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- 125000001153 fluoro group Chemical group F* 0.000 abstract 3
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 3
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 2
- JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical compound C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 abstract 2
- 125000001309 chloro group Chemical group Cl* 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- 125000004029 hydroxymethyl group Chemical group [H]OC([H])([H])* 0.000 abstract 2
- 125000000954 2-hydroxyethyl group Chemical group [H]C([*])([H])C([H])([H])O[H] 0.000 abstract 1
- 125000003349 3-pyridyl group Chemical group N1=C([H])C([*])=C([H])C([H])=C1[H] 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 125000006317 cyclopropyl amino group Chemical group 0.000 abstract 1
- 125000001559 cyclopropyl group Chemical group [H]C1([H])C([H])([H])C1([H])* 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 125000006525 methoxy ethyl amino group Chemical group [H]N(*)C([H])([H])C([H])([H])OC([H])([H])[H] 0.000 abstract 1
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 1
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 abstract 1
- 125000000168 pyrrolyl group Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US93833307P | 2007-05-16 | 2007-05-16 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR066472A1 true AR066472A1 (es) | 2009-08-19 |
Family
ID=39967594
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP080101931A AR066472A1 (es) | 2007-05-16 | 2008-05-07 | Compuesto de triazolil aminopirimidina, composicion farmaceutica que lo comprende y su uso para preparar un medicamento |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US8114872B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2155735A2 (cg-RX-API-DMAC7.html) |
| JP (1) | JP5204838B2 (cg-RX-API-DMAC7.html) |
| KR (1) | KR101131254B1 (cg-RX-API-DMAC7.html) |
| CN (1) | CN101679396B (cg-RX-API-DMAC7.html) |
| AR (1) | AR066472A1 (cg-RX-API-DMAC7.html) |
| AU (1) | AU2008254318B2 (cg-RX-API-DMAC7.html) |
| BR (1) | BRPI0811611A2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2687474A1 (cg-RX-API-DMAC7.html) |
| CL (1) | CL2008001322A1 (cg-RX-API-DMAC7.html) |
| EA (1) | EA015574B1 (cg-RX-API-DMAC7.html) |
| MX (1) | MX2009012233A (cg-RX-API-DMAC7.html) |
| PE (1) | PE20090803A1 (cg-RX-API-DMAC7.html) |
| TW (1) | TW200902012A (cg-RX-API-DMAC7.html) |
| WO (1) | WO2008144222A2 (cg-RX-API-DMAC7.html) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HRP20100641T1 (hr) | 2006-12-21 | 2010-12-31 | Eli Lilly And Company | Imidazolidinonilaminopirimidinski spojevi za liječenje raka |
| EP2125793B1 (en) | 2006-12-21 | 2010-09-01 | Eli Lilly & Company | Imidazolidinonyl aminopyrimidine compounds for the treatment of cancer |
| CN101679395B (zh) * | 2007-05-16 | 2012-06-13 | 伊莱利利公司 | 三唑基氨基嘧啶化合物 |
| CA2687474A1 (en) | 2007-05-16 | 2008-11-27 | Eli Lilly And Company | Triazolyl aminopyrimidine compounds |
| US9730447B2 (en) | 2013-04-15 | 2017-08-15 | E I Du Pont De Nemours And Company | Fungicidal amides |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4929726A (en) * | 1988-02-09 | 1990-05-29 | Georgia State University Foundation, Inc. | Novel diazines and their method of preparation |
| WO2004063192A1 (en) | 2003-01-10 | 2004-07-29 | Pharmacopeia Drug Discovery, Inc. | Imidazolyl pyrimidine derivatives useful as il-8 receptor modulators |
| GB0308466D0 (en) | 2003-04-11 | 2003-05-21 | Novartis Ag | Organic compounds |
| US7521457B2 (en) * | 2004-08-20 | 2009-04-21 | Boehringer Ingelheim International Gmbh | Pyrimidines as PLK inhibitors |
| JP2008510771A (ja) * | 2004-08-27 | 2008-04-10 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | ジヒドロプテリジノン、その製造方法および医薬薬剤としてのその使用 |
| CA2590939C (en) * | 2004-12-17 | 2011-10-18 | Amgen Inc. | Aminopyrimidine compounds and methods of use |
| TW200800201A (en) | 2005-11-18 | 2008-01-01 | Lilly Co Eli | Pyrimidinyl benzothiophene compounds |
| MX2008012482A (es) | 2006-03-31 | 2008-10-10 | Abbott Lab | Compuestos de indazol. |
| EP2125793B1 (en) | 2006-12-21 | 2010-09-01 | Eli Lilly & Company | Imidazolidinonyl aminopyrimidine compounds for the treatment of cancer |
| CN101679395B (zh) | 2007-05-16 | 2012-06-13 | 伊莱利利公司 | 三唑基氨基嘧啶化合物 |
| CA2687474A1 (en) | 2007-05-16 | 2008-11-27 | Eli Lilly And Company | Triazolyl aminopyrimidine compounds |
-
2008
- 2008-05-07 CA CA2687474A patent/CA2687474A1/en not_active Abandoned
- 2008-05-07 MX MX2009012233A patent/MX2009012233A/es active IP Right Grant
- 2008-05-07 CN CN2008800159078A patent/CN101679396B/zh not_active Expired - Fee Related
- 2008-05-07 AR ARP080101931A patent/AR066472A1/es unknown
- 2008-05-07 US US12/596,957 patent/US8114872B2/en not_active Expired - Fee Related
- 2008-05-07 KR KR1020097023738A patent/KR101131254B1/ko not_active Expired - Fee Related
- 2008-05-07 TW TW097116887A patent/TW200902012A/zh unknown
- 2008-05-07 EA EA200971067A patent/EA015574B1/ru not_active IP Right Cessation
- 2008-05-07 BR BRPI0811611-3A2A patent/BRPI0811611A2/pt not_active IP Right Cessation
- 2008-05-07 EP EP08755094A patent/EP2155735A2/en not_active Withdrawn
- 2008-05-07 CL CL2008001322A patent/CL2008001322A1/es unknown
- 2008-05-07 AU AU2008254318A patent/AU2008254318B2/en not_active Ceased
- 2008-05-07 JP JP2010508499A patent/JP5204838B2/ja not_active Expired - Fee Related
- 2008-05-07 PE PE2008000797A patent/PE20090803A1/es not_active Application Discontinuation
- 2008-05-07 WO PCT/US2008/062799 patent/WO2008144222A2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| CL2008001322A1 (es) | 2009-05-22 |
| TW200902012A (en) | 2009-01-16 |
| KR101131254B1 (ko) | 2012-04-24 |
| US20100130466A1 (en) | 2010-05-27 |
| EA200971067A1 (ru) | 2010-04-30 |
| WO2008144222A2 (en) | 2008-11-27 |
| AU2008254318A1 (en) | 2008-11-27 |
| MX2009012233A (es) | 2009-12-01 |
| JP2010527364A (ja) | 2010-08-12 |
| CA2687474A1 (en) | 2008-11-27 |
| AU2008254318B2 (en) | 2012-04-05 |
| EA015574B1 (ru) | 2011-10-31 |
| CN101679396B (zh) | 2012-06-06 |
| BRPI0811611A2 (pt) | 2014-11-04 |
| WO2008144222A3 (en) | 2009-01-15 |
| PE20090803A1 (es) | 2009-07-11 |
| JP5204838B2 (ja) | 2013-06-05 |
| US8114872B2 (en) | 2012-02-14 |
| CN101679396A (zh) | 2010-03-24 |
| KR20090130246A (ko) | 2009-12-21 |
| EP2155735A2 (en) | 2010-02-24 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CR9314A (es) | Derivado de espirocetal y uso del mismo como medicina para la diabetes | |
| CL2012001133A1 (es) | Composicion farmaceutica oral que comprende ponatinib 3-(imidazo[1,2-b]piridazin-3-iletinil)-4-metil-n-(4-((4-metilpiperazin-1-il)-metil)-3-(trifluorometil)fenil)benzamida y al menos un excipiente farmaceuticamente aceptable; y su uso para el tratamiento de neoplasma, cancer o un trastorno hiperproliferativo. | |
| AR066473A1 (es) | Compuesto de triazolil aminopirimidina, composicion farmaceutica que lo comprende y su uso para preparar un medicamento util para tratar cancer | |
| AR071187A1 (es) | Compuesto de arilmetil-tiazinamina, composicion farmaceutica que lo comprende y su uso para preparar un medicamento para el tratamiento de la enfermedad de alzheimer | |
| AR062886A1 (es) | Compuestos de tiazol pirazolopirimidina, composicion farmaceutica que lo comprende y su uso para preparar un medicamento | |
| EA201001013A1 (ru) | Бис(сульфониламино)производные для применения в терапии | |
| NZ612544A (en) | Heterocyclic compounds suitable for the treatment of dyslipidemia | |
| MX2009011997A (es) | Derivados de pirrolopirimidin-7-ona y su uso como farmaceuticos. | |
| GEP20125487B (en) | Organic compounds and their use | |
| EA201001368A1 (ru) | Гетероциклические производные мочевины и способы их применения-211 | |
| PE20100083A1 (es) | Combinaciones de drogas que comprenden un inhibidor de dgat y un agonista de ppar | |
| PE20091556A1 (es) | Derivado heterociclico fusionado y su uso | |
| UY30183A1 (es) | Derivados de quinolina | |
| PE20130239A1 (es) | Compuestos heteroaril-aril-ureas como inhibidores de la quinasa | |
| AR064692A1 (es) | Derivados de oxindol sustituido medicamentos que los comprenden y uso de los mismos | |
| AR083020A1 (es) | Uso de un compuesto de [3-(1-(1h-imidazol-4-il)etil)-2-metilfenil]metanol para preparar un medicamento util para tratar enfermedades y afecciones de la piel, articulo de fabricacion y composicion farmaceutica que lo comprenden | |
| NO20084659L (no) | Ko-krystall av C-glucosidderivat og L-prolin | |
| NZ590355A (en) | Stat3 inhibitor containing quinolinecarboxamide derivative as active ingredient | |
| CR11483A (es) | Inhibidores de peptido desformilasa | |
| SV2010003596A (es) | Sales farmaceuticamente aceptables de (3-{[[3-(6_amino-2-butoxi-8-oxo-7,8-dihidro-9h-purin-9-il) propil](3-morfolin-4-ilpropil)amino] metil} fenil) acetato de metilo y sus usos en terapia | |
| UY29991A1 (es) | Sales, profármacos y formulaciones de 1-(5-(4-amino-7-isopropil-7h-pirrolo(2,3-d)pirimidin-5-carbonil)-2-metoxi-fenil)-3-(2,4-dicloro-fenil)-urea | |
| UA107324C2 (uk) | Похідні 1,2,3-триазолу для застосування як інгібіторів стеароїл-coa десатурази | |
| EA201000702A1 (ru) | Некоторые производные 2-пиразинона и их применение в качестве ингибиторов нейтрофильной эластазы | |
| PH12012500643A1 (en) | Novel phenol derivative | |
| EA200971069A1 (ru) | Метаболиты производных (тио)карбомоилциклогексана |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |