AR063166A1 - Vector de expresion de multiples genes - Google Patents
Vector de expresion de multiples genesInfo
- Publication number
- AR063166A1 AR063166A1 ARP070104442A ARP070104442A AR063166A1 AR 063166 A1 AR063166 A1 AR 063166A1 AR P070104442 A ARP070104442 A AR P070104442A AR P070104442 A ARP070104442 A AR P070104442A AR 063166 A1 AR063166 A1 AR 063166A1
- Authority
- AR
- Argentina
- Prior art keywords
- mgev
- expression vector
- multiple genes
- domains
- segments
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/81—Protease inhibitors
- C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
- C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
- C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
- C12N15/8279—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
- C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
- C12N15/8279—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance
- C12N15/8286—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance for insect resistance
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
- Y02A40/10—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in agriculture
- Y02A40/146—Genetically Modified [GMO] plants, e.g. transgenic plants
Landscapes
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmacology & Pharmacy (AREA)
- Insects & Arthropods (AREA)
- Pest Control & Pesticides (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
Abstract
Un vehículo de expresion multigénica (MGEV) que consiste esencialmente en un polinucleotido que comprende segmentos de 2 a 8 dominios, D, codificando cada dominio una proteína funcional, estando unido cada dominio al siguiente en una secuencia lineal mediante un segmento Ligante (L) que codifica un péptido Ligante, estando todos los segmentos D y L en el mismo marco de lectura, y por lo menos uno de los dominios no es un inhibidor de proteasa tipo dos. Reivindicacion 37: Un vector de expresion de MGEV que comprende un MGEV de acuerdo con la reivindicacion 36 bajo el control de expresion de un promotor activo en plantas.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US80320606P | 2006-05-25 | 2006-05-25 | |
PCT/AU2007/000712 WO2007137329A2 (en) | 2006-05-25 | 2007-05-24 | Multi-gene expression vehicle |
Publications (1)
Publication Number | Publication Date |
---|---|
AR063166A1 true AR063166A1 (es) | 2008-12-30 |
Family
ID=38779010
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP070104442A AR063166A1 (es) | 2006-05-25 | 2007-10-09 | Vector de expresion de multiples genes |
Country Status (12)
Country | Link |
---|---|
US (2) | US20070277263A1 (es) |
EP (1) | EP2027264B1 (es) |
JP (1) | JP2009537155A (es) |
CN (1) | CN101517077B (es) |
AR (1) | AR063166A1 (es) |
AU (1) | AU2007266307C1 (es) |
BR (1) | BRPI0712168A2 (es) |
CA (1) | CA2653404C (es) |
NZ (1) | NZ572795A (es) |
SG (1) | SG171689A1 (es) |
WO (1) | WO2007137329A2 (es) |
ZA (1) | ZA200809722B (es) |
Families Citing this family (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1366168B1 (en) | 2001-02-08 | 2011-05-18 | Hexima Limited | Plant-derived molecules and genetic sequences encoding same and uses therefor |
CN101848938A (zh) * | 2007-04-20 | 2010-09-29 | 赫希玛有限公司 | 经修饰的植物防卫素 |
AR075257A1 (es) | 2008-02-01 | 2011-03-23 | Hexima Ltd | Sistema de proteccion de plantas contra la infeccion por agentes patogenos |
WO2010015024A1 (en) * | 2008-08-05 | 2010-02-11 | Hexima Limited | Plant anti-pathogen systems |
US9889184B2 (en) | 2008-08-05 | 2018-02-13 | Hexima Limited | Anti-pathogen systems |
AU2012214102B2 (en) | 2011-02-07 | 2014-08-07 | Hexima Limited | Modified plant defensins useful as anti-pathogenic agents |
US8945876B2 (en) | 2011-11-23 | 2015-02-03 | University Of Hawaii | Auto-processing domains for polypeptide expression |
US11692016B2 (en) | 2012-03-09 | 2023-07-04 | Vestaron Corporation | High gene expression yeast strain |
EP3766978A1 (en) | 2012-03-09 | 2021-01-20 | Vestaron Corporation | Toxic peptide production, peptide expression in plants and combinations of cysteine rich peptides |
AU2013350317B2 (en) | 2012-11-23 | 2016-09-08 | Hexima Limited | Anti-pathogenic methods |
CN103114102B (zh) * | 2013-01-29 | 2014-12-03 | 华南农业大学 | 一种多基因载体组装方法与应用 |
RU2015143825A (ru) | 2013-03-15 | 2017-04-26 | Пайонир Хай-Бред Интернэшнл, Инк. | Полипептиды phi-4 и способы их применения |
US10006045B2 (en) | 2013-08-16 | 2018-06-26 | Pioneer Hi-Bred International, Inc. | Insecticidal proteins and methods for their use |
EP3692786B1 (en) | 2013-09-13 | 2022-11-02 | Pioneer Hi-Bred International, Inc. | Insecticidal proteins and methods for their use |
MX2016010187A (es) | 2014-02-07 | 2017-07-11 | Pioneer Hi Bred Int | Proteinas insecticidas y metodos para su uso. |
CA2938979C (en) | 2014-02-07 | 2024-02-20 | Pioneer Hi-Bred International, Inc. | Insecticidal proteins and methods for their use |
UA126192C2 (uk) | 2014-10-16 | 2022-08-31 | Піонір Хай-Бред Інтернешнл, Інк. | Інсектицидний білок та спосіб його застосування |
RU2017144238A (ru) | 2015-05-19 | 2019-06-19 | Пайонир Хай-Бред Интернэшнл, Инк. | Инсектицидные белки и способы их применения |
BR122023016256B8 (pt) | 2015-08-06 | 2024-04-30 | E I Du Pont De Nemours And Company | Polipeptídeo inseticida recombinante, polinucleotídeo recombinante, construto de dna, método de obtenção de uma planta transgênica ou célula de planta transgênica, composição, proteína de fusão, método para controlar uma praga, método para inibir crescimento ou para exterminar uma população de pragas e uso do polipeptídeo |
US20180325119A1 (en) | 2015-12-18 | 2018-11-15 | Pioneer Hi-Bred International, Inc. | Insecticidal proteins and methods for their use |
CA3020883A1 (en) * | 2016-03-11 | 2017-09-14 | Donald Danforth Plant Science Center | Multimeric defensin proteins and related methods |
MX2018013249A (es) | 2016-05-04 | 2019-02-13 | Pioneer Hi Bred Int | Proteinas insecticidas y metodos para sus usos. |
MX2018015906A (es) | 2016-07-01 | 2019-04-04 | Pioneer Hi Bred Int | Proteinas insecticidas de plantas y metodos para sus usos. |
US11535653B2 (en) | 2016-10-21 | 2022-12-27 | Vestaron Corporation | Cleavable peptides and insecticidal and nematicidal proteins comprising same |
US11021716B2 (en) | 2016-11-01 | 2021-06-01 | Pioneer Hi-Bred International, Inc. | Insecticidal proteins and methods for their use |
WO2018111551A1 (en) | 2016-12-14 | 2018-06-21 | Pioneer Hi-Bred International, Inc. | Insecticidal proteins and methods for their use |
EP3558004A1 (en) | 2016-12-22 | 2019-10-30 | Pioneer Hi-Bred International, Inc. | Insecticidal proteins and methods for their use |
CA3052794A1 (en) | 2017-02-08 | 2018-08-16 | Pioneer Hi-Bred International, Inc. | Insecticidal combinations of plant derived insecticidal proteins and methods for their use |
WO2018208882A1 (en) | 2017-05-11 | 2018-11-15 | Pioneer Hi-Bred International, Inc. | Insecticidal proteins and methods for their use |
BR112021003797A2 (pt) | 2018-08-29 | 2021-05-25 | Pioneer Hi-Bred International, Inc. | proteínas inseticidas e métodos para seu uso |
CN110157710B (zh) * | 2019-07-11 | 2022-12-27 | 贵州大学 | 花烟草NaD1基因启动子及其用途 |
CA3186978A1 (en) | 2020-07-14 | 2022-01-20 | Pioneer Hi-Bred International, Inc. | Insecticidal proteins and methods for their use |
Family Cites Families (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4945050A (en) * | 1984-11-13 | 1990-07-31 | Cornell Research Foundation, Inc. | Method for transporting substances into living cells and tissues and apparatus therefor |
US5036006A (en) * | 1984-11-13 | 1991-07-30 | Cornell Research Foundation, Inc. | Method for transporting substances into living cells and tissues and apparatus therefor |
US5100792A (en) * | 1984-11-13 | 1992-03-31 | Cornell Research Foundation, Inc. | Method for transporting substances into living cells and tissues |
US5482928A (en) * | 1991-03-11 | 1996-01-09 | Imperial Chemical Industries Plc | Biocidal proteins |
US5446127A (en) * | 1991-05-24 | 1995-08-29 | Universidad Politecnica De Madrid | Antipathogenic peptides and compositions containing the same |
US5538525A (en) * | 1991-08-29 | 1996-07-23 | Zeneca Limited | Biocidal proteins |
JP3657980B2 (ja) * | 1992-12-16 | 2005-06-08 | ヘキシマ・リミテッド | プロテイナーゼインヒビター、その前駆体およびそれをコードする遺伝子配列 |
CA2166309A1 (en) * | 1993-08-04 | 1995-02-16 | Willem Frans Broekaert | Antimicrobial proteins |
EP1231274A3 (en) * | 1994-11-21 | 2002-10-09 | The University Of Leeds | Modified porteinase inhibitors |
CN1145695C (zh) * | 1995-12-13 | 2004-04-14 | 辛甄塔有限公司 | 抗真菌蛋白 |
US6909032B2 (en) * | 1996-01-31 | 2005-06-21 | Commonwealth Scientific And Industrial Research Organisation | DNA encoding a macadamia integrifolia anti-microbial protein, constructs comprising the same and plant material comprising the constructs |
US5773696A (en) * | 1996-03-29 | 1998-06-30 | Monsanto Company | Antifungal polypeptide and methods for controlling plant pathogenic fungi |
US6121436A (en) * | 1996-12-13 | 2000-09-19 | Monsanto Company | Antifungal polypeptide and methods for controlling plant pathogenic fungi |
AUPO427596A0 (en) * | 1996-12-20 | 1997-01-23 | Cooperative Research Centre For Tropical Plant Pathology | Anti-microbial protein |
GB9725556D0 (en) * | 1997-12-03 | 1998-02-04 | Ciba Geigy Ag | Organic compounds |
WO2000011175A1 (en) * | 1998-08-18 | 2000-03-02 | Syngenta Limited | Genetic method for the expression of polyproteins in plants |
US6855865B2 (en) * | 1999-05-07 | 2005-02-15 | E.I. Du Pont De Nemours And Company | Nucleic acids encoding plant defensins and methods of use thereof |
US6677503B1 (en) * | 1999-06-23 | 2004-01-13 | Pioneer Hi-Bred International, Inc. | Sunflower anti-pathogene proteins and genes and their uses |
US6770750B2 (en) * | 1999-11-18 | 2004-08-03 | Korea Kumho Petrochemical Co., Ltd. | Small and cysteine rich antifungal defensin and thionin-like protein genes highly expressed in the incompatible interaction |
US20020059658A1 (en) * | 2000-06-15 | 2002-05-16 | Zhong-Min Wei | Methods of improving the effectiveness of transgenic plants |
US7141723B2 (en) * | 2001-01-29 | 2006-11-28 | Cargill, Incorporated | Transgenic plants resistant to Sclerotinia and Phoma lingam |
EP1366168B1 (en) * | 2001-02-08 | 2011-05-18 | Hexima Limited | Plant-derived molecules and genetic sequences encoding same and uses therefor |
EP1572880B1 (en) * | 2001-06-22 | 2014-01-22 | Pioneer Hi-Bred International, Inc. | Defensin polynucleotides and methods of use |
WO2003039804A1 (en) * | 2001-11-02 | 2003-05-15 | The Boeing Company | Apparatus and method for forming weld joints having compressive residual stress patterns |
CA2521940C (en) * | 2003-04-23 | 2010-01-26 | Latrobe University | Insect chymotrypsin and inhibitors thereof |
US20070197474A1 (en) * | 2004-03-30 | 2007-08-23 | Clinton William P | Methods for controlling plants pathogens using N-phosphonomethylglycine |
CN101848938A (zh) * | 2007-04-20 | 2010-09-29 | 赫希玛有限公司 | 经修饰的植物防卫素 |
-
2007
- 2007-05-24 US US11/753,072 patent/US20070277263A1/en not_active Abandoned
- 2007-05-24 JP JP2009511304A patent/JP2009537155A/ja active Pending
- 2007-05-24 EP EP07718958.7A patent/EP2027264B1/en not_active Not-in-force
- 2007-05-24 NZ NZ572795A patent/NZ572795A/en not_active IP Right Cessation
- 2007-05-24 WO PCT/AU2007/000712 patent/WO2007137329A2/en active Application Filing
- 2007-05-24 CN CN200780025123.9A patent/CN101517077B/zh not_active Expired - Fee Related
- 2007-05-24 CA CA2653404A patent/CA2653404C/en not_active Expired - Fee Related
- 2007-05-24 BR BRPI0712168-7A patent/BRPI0712168A2/pt not_active IP Right Cessation
- 2007-05-24 AU AU2007266307A patent/AU2007266307C1/en not_active Ceased
- 2007-05-24 SG SG201103492-3A patent/SG171689A1/en unknown
- 2007-10-09 AR ARP070104442A patent/AR063166A1/es unknown
-
2008
- 2008-11-14 ZA ZA200809722A patent/ZA200809722B/xx unknown
-
2014
- 2014-02-14 US US14/181,273 patent/US20140259231A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
WO2007137329A9 (en) | 2009-01-22 |
AU2007266307B2 (en) | 2012-05-31 |
SG171689A1 (en) | 2011-06-29 |
CN101517077A (zh) | 2009-08-26 |
JP2009537155A (ja) | 2009-10-29 |
ZA200809722B (en) | 2009-11-25 |
WO2007137329A2 (en) | 2007-12-06 |
US20140259231A1 (en) | 2014-09-11 |
EP2027264A4 (en) | 2010-02-03 |
CA2653404A1 (en) | 2007-12-06 |
CN101517077B (zh) | 2014-04-16 |
NZ572795A (en) | 2011-06-30 |
AU2007266307C1 (en) | 2012-10-25 |
AU2007266307A1 (en) | 2007-12-06 |
WO2007137329A3 (en) | 2009-06-18 |
CA2653404C (en) | 2015-06-30 |
EP2027264B1 (en) | 2014-10-29 |
BRPI0712168A2 (pt) | 2012-03-13 |
US20070277263A1 (en) | 2007-11-29 |
EP2027264A2 (en) | 2009-02-25 |
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