AR058892A1 - Metodos para tratar lupus cutaneo con el uso de compuestos de aminoisoindolina - Google Patents

Metodos para tratar lupus cutaneo con el uso de compuestos de aminoisoindolina

Info

Publication number
AR058892A1
AR058892A1 ARP060105863A ARP060105863A AR058892A1 AR 058892 A1 AR058892 A1 AR 058892A1 AR P060105863 A ARP060105863 A AR P060105863A AR P060105863 A ARP060105863 A AR P060105863A AR 058892 A1 AR058892 A1 AR 058892A1
Authority
AR
Argentina
Prior art keywords
methods
cutaneo
lutus
aminoisoindoline
treat
Prior art date
Application number
ARP060105863A
Other languages
English (en)
Original Assignee
Celgene Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Celgene Corp filed Critical Celgene Corp
Publication of AR058892A1 publication Critical patent/AR058892A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/4035—Isoindoles, e.g. phthalimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/5575—Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Abstract

Métodos de tratamiento de lupus cutáneo en un ser humano. Los métodos espcíficos comprenden la administracion de (+)-2-[1-(3-etoxi-4-metoxifenil)-2-metilsulfoniletil]-4-acetilaminoisoindolin-1,3-diona, 4-(amino)-2-(2,6-dioxo(3-piperidil))-isoindolin- 1,3-diona (ACTIMIDTM), 3-(4-amino-1-oxo-1,3-dihidro-isoindol-2-il)-piperidin-2,6-diona (REVLIMID(R)), o 2-[(1S)-1-(3-etoxi-4-metoxifenil)-2-(metilsulfonil)etil]-3-oxoisoindolin-4-il}carboxamida de ciclopropilo, solas o de modo alternativo, en combinacion con un segundo agente activo.
ARP060105863A 2005-12-29 2006-12-28 Metodos para tratar lupus cutaneo con el uso de compuestos de aminoisoindolina AR058892A1 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US75524605P 2005-12-29 2005-12-29
US75479505P 2005-12-29 2005-12-29
US78743606P 2006-03-30 2006-03-30

Publications (1)

Publication Number Publication Date
AR058892A1 true AR058892A1 (es) 2008-02-27

Family

ID=38024363

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP060105863A AR058892A1 (es) 2005-12-29 2006-12-28 Metodos para tratar lupus cutaneo con el uso de compuestos de aminoisoindolina

Country Status (14)

Country Link
US (2) US20070155791A1 (es)
EP (1) EP1965793A1 (es)
JP (1) JP5243267B2 (es)
KR (1) KR20080086527A (es)
AR (1) AR058892A1 (es)
AU (1) AU2006332677B2 (es)
CA (1) CA2635252A1 (es)
EA (1) EA013973B1 (es)
IL (1) IL192456A0 (es)
MX (1) MX2008008405A (es)
NZ (1) NZ569563A (es)
PE (1) PE20071184A1 (es)
TW (1) TW200733957A (es)
WO (1) WO2007079182A1 (es)

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US20070155791A1 (en) 2007-07-05
EA013973B1 (ru) 2010-08-30
US20110104144A1 (en) 2011-05-05
AU2006332677A1 (en) 2007-07-12
MX2008008405A (es) 2008-09-12
KR20080086527A (ko) 2008-09-25
TW200733957A (en) 2007-09-16
WO2007079182A1 (en) 2007-07-12
PE20071184A1 (es) 2007-11-30
JP2009522289A (ja) 2009-06-11
EA200870128A1 (ru) 2008-12-30
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IL192456A0 (en) 2009-08-03
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