AR053737A1 - Formulacion pediatrica de topiramato - Google Patents
Formulacion pediatrica de topiramatoInfo
- Publication number
- AR053737A1 AR053737A1 ARP060102160A ARP060102160A AR053737A1 AR 053737 A1 AR053737 A1 AR 053737A1 AR P060102160 A ARP060102160 A AR P060102160A AR P060102160 A ARP060102160 A AR P060102160A AR 053737 A1 AR053737 A1 AR 053737A1
- Authority
- AR
- Argentina
- Prior art keywords
- composition
- topiramato
- liquid
- pediatric formulation
- topiramate
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 6
- KJADKKWYZYXHBB-XBWDGYHZSA-N Topiramic acid Chemical compound C1O[C@@]2(COS(N)(=O)=O)OC(C)(C)O[C@H]2[C@@H]2OC(C)(C)O[C@@H]21 KJADKKWYZYXHBB-XBWDGYHZSA-N 0.000 title abstract 2
- 238000009472 formulation Methods 0.000 title 1
- 239000007788 liquid Substances 0.000 abstract 2
- 239000004480 active ingredient Substances 0.000 abstract 1
- 239000000654 additive Chemical class 0.000 abstract 1
- 230000000996 additive effect Effects 0.000 abstract 1
- 239000012736 aqueous medium Substances 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229960004394 topiramate Drugs 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Pain & Pain Management (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP05104491 | 2005-05-25 | ||
| US69039105P | 2005-06-14 | 2005-06-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR053737A1 true AR053737A1 (es) | 2007-05-16 |
Family
ID=35045349
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP060102160A AR053737A1 (es) | 2005-05-25 | 2006-05-24 | Formulacion pediatrica de topiramato |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20060270611A1 (enExample) |
| EP (1) | EP1888030A1 (enExample) |
| JP (1) | JP2008542237A (enExample) |
| CN (1) | CN101257889A (enExample) |
| AR (1) | AR053737A1 (enExample) |
| AU (1) | AU2006251213A1 (enExample) |
| BR (1) | BRPI0610210A2 (enExample) |
| CA (1) | CA2609719A1 (enExample) |
| MX (1) | MX2007014713A (enExample) |
| RU (1) | RU2007148444A (enExample) |
| TW (1) | TW200716202A (enExample) |
| WO (1) | WO2006125774A1 (enExample) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2246044A1 (en) * | 2009-04-21 | 2010-11-03 | Pierre Fabre Dermo-Cosmétique | Paediatric solutions comprising a beta-blocker |
| JP5840201B2 (ja) | 2010-05-10 | 2016-01-06 | ユーロ−セルティーク エス.エイ. | 活性剤を負荷した顆粒と追加の活性剤の組合せ |
| ES2642788T3 (es) | 2010-05-10 | 2017-11-20 | Euro-Celtique S.A. | Fabricación de gránulos sin principio activo y de comprimidos que comprenden los mismos |
| CA2795324C (en) * | 2012-11-09 | 2015-07-14 | Purdue Pharma | Pharmaceutical compositions comprising hydromorphone and naloxone |
| US9549909B2 (en) | 2013-05-03 | 2017-01-24 | The Katholieke Universiteit Leuven | Method for the treatment of dravet syndrome |
| EP3068397A1 (en) | 2013-11-13 | 2016-09-21 | Euro-Celtique S.A. | Hydromorphone and naloxone for treatment of pain and opioid bowel dysfunction syndrome |
| CN104188920A (zh) * | 2014-07-28 | 2014-12-10 | 安徽省逸欣铭医药科技有限公司 | 托吡酯颗粒剂及其制备方法 |
| PT3340971T (pt) * | 2015-08-24 | 2024-06-05 | Zogenix International Ltd | Métodos de tratamento da síndrome de lennox-gastaut com utilização de fenfluramina |
| US9901576B2 (en) | 2015-11-20 | 2018-02-27 | West-Ward Pharmaceuticals International Limited | Stable formulation of phenobarbital sodium injection |
| JP2019507111A (ja) | 2015-12-22 | 2019-03-14 | ゾゲニクス インターナショナル リミテッド | 代謝抵抗性フェンフルラミン類縁体およびその使用法 |
| KR102688278B1 (ko) | 2015-12-22 | 2024-07-26 | 조게닉스 인터내셔널 리미티드 | 펜플루라민 조성물 및 그 제조 방법 |
| CA3032996C (en) | 2016-08-24 | 2025-05-06 | Zogenix International Ltd | Formulation for inhibiting formation of 5-ht 2b agonists and methods of using same |
| US10682317B2 (en) | 2017-09-26 | 2020-06-16 | Zogenix International Limited | Ketogenic diet compatible fenfluramine formulation |
| WO2019186515A1 (en) * | 2018-03-30 | 2019-10-03 | Ftf Pharma Private Limited | Liquid pharmaceutical compositions of antiepileptic drugs |
| CA3097335A1 (en) | 2018-05-11 | 2019-11-14 | Zogenix International Limited | Compositions and methods for treating seizure-induced sudden death |
| WO2019241005A1 (en) | 2018-06-14 | 2019-12-19 | Zogenix International Limited | Compositions and methods for treating respiratory depression with fenfluramine |
| GB2596184A (en) * | 2018-09-13 | 2021-12-22 | Ftf Pharma Private Ltd | Non-aqueous solutions for oral dosage |
| AU2019384963B2 (en) | 2018-11-19 | 2022-05-26 | Zogenix International Limited | Methods of treating Rett syndrome using fenfluramine |
| WO2020104837A1 (en) | 2018-11-21 | 2020-05-28 | Rosemont Pharmaceuticals Limited | Oral topiramate suspension formulations with extended shelf stability and enhanced bioavailability |
| US20210169844A1 (en) * | 2019-12-10 | 2021-06-10 | Tulex Pharmaceuticals Inc. | Compositions and methods for treating epilepsy, seizures and other conditions |
| GB2594242A (en) * | 2020-04-14 | 2021-10-27 | Syri Ltd | A stable and ready to administer liquid pharmaceutical composition of topiramate |
| US11612574B2 (en) | 2020-07-17 | 2023-03-28 | Zogenix International Limited | Method of treating patients infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) |
| CN117159458A (zh) * | 2022-05-27 | 2023-12-05 | 北京万全德众医药生物技术有限公司 | 托吡酯口服溶液及其制备方法 |
| US12109188B1 (en) | 2023-03-24 | 2024-10-08 | Tap Pharmaceuticals Ag | Liquid pharmaceutical formulations of topiramate |
| US12290504B2 (en) | 2023-04-11 | 2025-05-06 | Tap Pharmaceuticals Ag | Aqueous formulations of topiramate |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4513006A (en) * | 1983-09-26 | 1985-04-23 | Mcneil Lab., Inc. | Anticonvulsant sulfamate derivatives |
| AU651244B2 (en) * | 1991-09-19 | 1994-07-14 | Mcneilab, Inc. | Process for the preparation of chlorosulfate and sulfamate derivatives of 2,3:4,5-bis-0-(1-methylethylidene)-beta-D- fructopyranose and (1-methylcyclohexyl)methanol |
| US20030077227A1 (en) * | 1997-10-01 | 2003-04-24 | Dugger Harry A. | Buccal, polar and non-polar spray or capsule containing drugs for treating disorders of the central nervous system |
| JP2004331502A (ja) * | 2001-06-18 | 2004-11-25 | Ortho Mcneil Pharmaceut Inc | 視神経細胞保護剤 |
| US6559293B1 (en) * | 2002-02-15 | 2003-05-06 | Transform Pharmaceuticals, Inc. | Topiramate sodium trihydrate |
| US20050129765A1 (en) * | 2003-11-14 | 2005-06-16 | Shaoling Li | Controlled release of topiramate in liquid dosage forms |
-
2006
- 2006-05-23 JP JP2008512825A patent/JP2008542237A/ja not_active Withdrawn
- 2006-05-23 RU RU2007148444/15A patent/RU2007148444A/ru not_active Application Discontinuation
- 2006-05-23 AU AU2006251213A patent/AU2006251213A1/en not_active Abandoned
- 2006-05-23 MX MX2007014713A patent/MX2007014713A/es not_active Application Discontinuation
- 2006-05-23 CA CA002609719A patent/CA2609719A1/en not_active Abandoned
- 2006-05-23 US US11/419,834 patent/US20060270611A1/en not_active Abandoned
- 2006-05-23 WO PCT/EP2006/062518 patent/WO2006125774A1/en not_active Ceased
- 2006-05-23 BR BRPI0610210-7A patent/BRPI0610210A2/pt not_active IP Right Cessation
- 2006-05-23 EP EP06755288A patent/EP1888030A1/en not_active Withdrawn
- 2006-05-23 CN CNA2006800178845A patent/CN101257889A/zh active Pending
- 2006-05-24 TW TW095118344A patent/TW200716202A/zh unknown
- 2006-05-24 AR ARP060102160A patent/AR053737A1/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| RU2007148444A (ru) | 2009-06-27 |
| WO2006125774A1 (en) | 2006-11-30 |
| BRPI0610210A2 (pt) | 2010-06-01 |
| AU2006251213A1 (en) | 2006-11-30 |
| CN101257889A (zh) | 2008-09-03 |
| US20060270611A1 (en) | 2006-11-30 |
| MX2007014713A (es) | 2008-02-14 |
| JP2008542237A (ja) | 2008-11-27 |
| TW200716202A (en) | 2007-05-01 |
| EP1888030A1 (en) | 2008-02-20 |
| CA2609719A1 (en) | 2006-11-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal |