AR053406A1 - Derivados de piperidina como inhibidores de renina. composiciones farmaceuticas - Google Patents

Derivados de piperidina como inhibidores de renina. composiciones farmaceuticas

Info

Publication number
AR053406A1
AR053406A1 ARP050102851A ARP050102851A AR053406A1 AR 053406 A1 AR053406 A1 AR 053406A1 AR P050102851 A ARP050102851 A AR P050102851A AR P050102851 A ARP050102851 A AR P050102851A AR 053406 A1 AR053406 A1 AR 053406A1
Authority
AR
Argentina
Prior art keywords
alkyl
alkoxy
ylalkyl
alkoxyc
oxo
Prior art date
Application number
ARP050102851A
Other languages
English (en)
Spanish (es)
Original Assignee
Speedel Experimenta Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Speedel Experimenta Ag filed Critical Speedel Experimenta Ag
Publication of AR053406A1 publication Critical patent/AR053406A1/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/06Antiglaucoma agents or miotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Hospice & Palliative Care (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
ARP050102851A 2004-07-09 2005-07-08 Derivados de piperidina como inhibidores de renina. composiciones farmaceuticas AR053406A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH11582004 2004-07-09

Publications (1)

Publication Number Publication Date
AR053406A1 true AR053406A1 (es) 2007-05-09

Family

ID=35448323

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP050102851A AR053406A1 (es) 2004-07-09 2005-07-08 Derivados de piperidina como inhibidores de renina. composiciones farmaceuticas

Country Status (14)

Country Link
US (1) US20080076766A1 (OSRAM)
EP (1) EP1776359B1 (OSRAM)
JP (1) JP4842262B2 (OSRAM)
CN (1) CN101014594A (OSRAM)
AR (1) AR053406A1 (OSRAM)
AT (1) ATE521607T1 (OSRAM)
BR (1) BRPI0513199A (OSRAM)
CA (1) CA2570920A1 (OSRAM)
ES (1) ES2372502T3 (OSRAM)
IL (1) IL180242A0 (OSRAM)
PL (1) PL1776359T3 (OSRAM)
PT (1) PT1776359E (OSRAM)
TW (1) TW200613274A (OSRAM)
WO (1) WO2006005741A2 (OSRAM)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008510755A (ja) 2004-08-25 2008-04-10 アクテリオン ファーマシューティカルズ リミテッド ビシクロノネン誘導体
GB0428526D0 (en) 2004-12-30 2005-02-09 Novartis Ag Organic compounds
EP1707202A1 (de) * 2005-03-31 2006-10-04 Speedel Experimenta AG Organische Verbindungen
TW200722424A (en) * 2005-03-31 2007-06-16 Speedel Experimenta Ag Substituted piperidines
BRPI0609534A2 (pt) * 2005-03-31 2010-04-13 Speedel Experimenta Ag piperidinas 3,4,5-substituìdas
GB0508992D0 (en) * 2005-05-03 2005-06-08 Novartis Ag Organic compounds
GB0510810D0 (en) * 2005-05-26 2005-06-29 Novartis Ag Organic compounds
KR100963455B1 (ko) 2005-05-27 2010-06-18 액테리온 파마슈티칼 리미티드 신규한 피페리딘 카르복실산 아미드 유도체
GB0514203D0 (en) 2005-07-11 2005-08-17 Novartis Ag Organic compounds
ES2430139T3 (es) 2005-12-30 2013-11-19 Novartis Ag Compuestos de piperidina 3,5-sustituido como inhibidores de renina
EP1816122A3 (en) * 2006-01-19 2007-09-19 Speedel Experimenta AG 3,4,5-substituted piperidines as therapeutic compounds
TW200804359A (en) * 2006-01-19 2008-01-16 Speedel Experimenta Ag Substituted 4-phenylpiperidines
TW200821303A (en) * 2006-08-08 2008-05-16 Speedel Experimenta Ag Organic compounds
EP1911758A1 (en) * 2006-10-04 2008-04-16 Speedel Experimenta AG Phenyl piperidine derivatives for use as renin inhibitors
EP1908761A1 (en) * 2006-10-04 2008-04-09 Speedel Experimenta AG Organic compounds
WO2008074450A2 (en) * 2006-12-20 2008-06-26 Nicox S.A. Non-peptidic renin inhibitors nitroderivatives
TWI452044B (zh) * 2007-06-15 2014-09-11 Mitsubishi Tanabe Pharma Corp 嗎啉衍生物
EP2181105B1 (en) 2007-06-25 2015-04-29 Novartis AG N5-(2-ethoxyethyl)-n3-(2-pyridinyl)-3,5-piperidinedicarboxamide derivatives for use as renin inhibitors
AR069005A1 (es) * 2007-10-25 2009-12-23 Speedel Experimenta Ag Piperidinas 4,4-disustituidas
TW200932241A (en) * 2007-12-05 2009-08-01 Speedel Experimenta Ag Organic compounds
JP2011511038A (ja) 2008-02-08 2011-04-07 ノバルティス アーゲー レニン阻害剤としての置換ピペリジン
EA201001239A1 (ru) 2008-02-08 2011-04-29 Новартис Аг Замещённые пиперидины в качестве ингибиторов ренина
WO2009106599A2 (en) * 2008-02-29 2009-09-03 Novartis Ag Substituted piperidines as therapeutic compounds
WO2009127251A1 (en) * 2008-04-16 2009-10-22 Novartis Ag Combinations comprising a renin inhibitor
CN102015682B (zh) * 2008-05-05 2014-07-16 埃科特莱茵药品有限公司 作为肾素抑制剂的3,4-取代的哌啶衍生物
PE20110067A1 (es) 2008-06-19 2011-02-18 Takeda Pharmaceutical Derivados de piperidina como inhibidores de renina
EP2163245A1 (en) 2008-09-10 2010-03-17 Novartis Ag Renin inhibitors for the treatment of psoriasis
US8592454B2 (en) 2008-09-19 2013-11-26 Takeda Pharmaceutical Company Limited Nitrogen-containing heterocyclic compound and use of same
US20120035214A1 (en) * 2009-04-03 2012-02-09 Merck Canada Inc. Renin inhibitors
EP2384745A3 (en) * 2010-05-05 2012-01-18 Sanovel Ilac Sanayi ve Ticaret A.S. Modified release pharmaceutical compositions of dexlansoprazole
EP2384746A3 (en) 2010-05-05 2012-03-07 Sanovel Ilac Sanayi ve Ticaret A.S. Dual release oral tablet compositions of dexlansoprazole
US8563035B2 (en) 2010-05-05 2013-10-22 Sanovel Ilac Sanayi Ve Ticaret Anomin Sirketi Oral tablet compositions of dexlansoprazole
EP4255909A1 (en) * 2020-12-02 2023-10-11 Qurient Co. Ltd. Compounds having cyclin-dependent kinase(cdk)-inhibitory function
JP2025510646A (ja) 2022-03-14 2025-04-15 スラップ ファーマシューティカルズ エルエルシー 多環式化合物

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100384979B1 (ko) * 1995-09-07 2003-10-17 에프. 호프만-라 로슈 아게 심부전증및신부전증치료용의신규한4-(옥시알콕시페닐)-3-옥시-피페리딘
US6376672B1 (en) * 1999-04-27 2002-04-23 Hoffmann-La Roche Inc. Naphthalenylmethoxypiperidines as renin inhibitors
US6197959B1 (en) * 1999-04-27 2001-03-06 Hoffmann-La Roche Inc. Piperidine derivatives
US20030095958A1 (en) * 2001-04-27 2003-05-22 Bhisetti Govinda R. Inhibitors of bace
US20040204455A1 (en) * 2003-04-10 2004-10-14 Cody Wayne Livingston Piperidine derivative rennin inhibitors

Also Published As

Publication number Publication date
CA2570920A1 (en) 2006-01-19
EP1776359A2 (en) 2007-04-25
PL1776359T3 (pl) 2012-01-31
ES2372502T3 (es) 2012-01-20
JP4842262B2 (ja) 2011-12-21
EP1776359B1 (en) 2011-08-24
CN101014594A (zh) 2007-08-08
JP2008505871A (ja) 2008-02-28
BRPI0513199A (pt) 2008-04-29
HK1104037A1 (en) 2008-01-04
WO2006005741A3 (en) 2006-07-06
PT1776359E (pt) 2011-12-15
TW200613274A (en) 2006-05-01
WO2006005741A2 (en) 2006-01-19
ATE521607T1 (de) 2011-09-15
IL180242A0 (en) 2007-07-04
US20080076766A1 (en) 2008-03-27

Similar Documents

Publication Publication Date Title
AR053406A1 (es) Derivados de piperidina como inhibidores de renina. composiciones farmaceuticas
AR066999A2 (es) Piperidinas sustituidas, preparados farmaceuticos y uso como inhibidores de renina
HRP20140111T1 (hr) Antagonisti receptora za cgrp
AR036716A1 (es) Un compuesto derivado de bencimidazolidinona, metodos que lo utilizan, una composicion farmaceutica que lo comprende y uso de dicho compuesto o composicion
HRP20171999T1 (hr) Novi derivati aminopirimidina
PE20160751A1 (es) Moduladores de tetrahidropiridopirazinas de gpr6
AR056197A1 (es) Derivados de 7-metilimidazol[1,2-a]piridin-6-il-8-metil-nonamidas como inhibidores de la renina, composciones farmaceuticas que los contienen y su uso en la fabricacion de un medicamento para el tratamiento de la hipertension arterial
AR057810A1 (es) Inhibidores ns5b de vhc de indolobenzazepina fusionados a ciclopropilo y composicion farmaceutica
AR048320A1 (es) Derivados de 5-amino-4-hidroxi-7-(1h-indolilmetil)-8-metilnonanamida
PE20030062A1 (es) Derivados aralquilsulfonil-3-(pirrol-2-ilmetiliden)-2-indolinona como inhibidores de quinasas
RU2008112290A (ru) Производные пиридазинона, используемые для лечения боли
AR060537A1 (es) 1,2,4-triazoles trisustituidos
CO6251260A2 (es) Derivados de bifenilo conformacionalmente restringido para uso como inhibidores del virus de la hepatitis c.
CO6180426A2 (es) Compuesto para el tratamiento de la hepatitis b
AR033295A1 (es) Compuestos biciclicos de pirimidina, proceso para su obtencion, uso de los mismos para la preparacion de una composicion farmaceutica y dicha composicion farmaceutica
PE20060775A1 (es) Derivados de pirrolidilo de compuestos heteroaromaticos como inhibidores de fosfodiesterasa
PE20130306A1 (es) Morfolinopirimidinas y su uso en terapia
AR040566A1 (es) Derivados de 1-heterociclilalquil 3- sulfonilazaindol o azaindazol como ligandos de 5 hidroxitriptamina-6
AR043180A1 (es) Derivados de heterociclil-3-sulfonilazaindol o -azaindazol como ligandos de 5-hidroxitriptamina-6
AR071763A1 (es) Pirazoles trisustituidos, composiciones farmaceuticas que los contienen, y usos de los mismos en el tratamiento de trastornos neurologicos y psiquiatricos
PE20091095A1 (es) Moduladores de gamma secretasa
NZ237189A (en) N-(4-piperidinyl)(dihydro benzofuran or dihydro-2h-benzopyran) carboxamide derivatives and pharmaceutical compositions
AR035991A1 (es) Derivados de benzimidazoles e imidazopiridinas, un procedimiento para su preparacion, composiciones farmaceuticas, un procedimiento para su preparacion, y un medicamento utiles como inhibidores de la replicacion del virus sincitial respiratorio
AR040567A1 (es) Derivados de 1- heterociclilalquil 3- sulfonilindol o -indazol como ligandos de 5- hidroxitriptamina -6
RU2007137649A (ru) 2-(4-оксо-4н-хиназолин-3-ил)ацетамиды и их использование в качестве вазопрессин v3 антагонистов

Legal Events

Date Code Title Description
FA Abandonment or withdrawal