AR048987A1 - Proceso enzimatico para desacetilacion de un acetato de fe-noxi-alquinilo para dar el correspondiente alcohol - Google Patents

Proceso enzimatico para desacetilacion de un acetato de fe-noxi-alquinilo para dar el correspondiente alcohol

Info

Publication number
AR048987A1
AR048987A1 ARP050102313A ARP050102313A AR048987A1 AR 048987 A1 AR048987 A1 AR 048987A1 AR P050102313 A ARP050102313 A AR P050102313A AR P050102313 A ARP050102313 A AR P050102313A AR 048987 A1 AR048987 A1 AR 048987A1
Authority
AR
Argentina
Prior art keywords
deactilation
alquinyl
noxi
acetate
give
Prior art date
Application number
ARP050102313A
Other languages
English (en)
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of AR048987A1 publication Critical patent/AR048987A1/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/14Nitrogen or oxygen as hetero atom and at least one other diverse hetero ring atom in the same ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D279/00Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/101,4-Thiazines; Hydrogenated 1,4-thiazines
    • C07D279/121,4-Thiazines; Hydrogenated 1,4-thiazines not condensed with other rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Un proceso para la preparacion del compuesto de la formula (2) mediante la reaccion del compuesto de la formula (1) con una enzima que puede hidrolizar la union de éster en donde * indica un centro quiral, R1 y R2 representan cada uno independientemente H, alquilo C1-6, -CN o -CCH, y R3 y R4 representan cada uno independientemente H o alquilo C1-6. Reivindicacion 1: Un proceso para preparar un compuesto de la formula (2) comprendiendo dicho proceso hacer reaccionar un compuesto de la formula (1) en un solvente adecuado y a una temperatura y pH adecuados, con una enzima hidrolizante de ésteres, en el cual * indica un centro quiral, R1 y R2 se seleccionan cada uno independientemente del grupo que consiste en H, alquilo C1-6, -CN y -CCH, y R3 y R4 se seleccionan cada uno independientemente del grupo que consiste en H y alquilo C1-6.
ARP050102313A 2004-06-08 2005-06-07 Proceso enzimatico para desacetilacion de un acetato de fe-noxi-alquinilo para dar el correspondiente alcohol AR048987A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US57779104P 2004-06-08 2004-06-08

Publications (1)

Publication Number Publication Date
AR048987A1 true AR048987A1 (es) 2006-06-14

Family

ID=34971935

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP050102313A AR048987A1 (es) 2004-06-08 2005-06-07 Proceso enzimatico para desacetilacion de un acetato de fe-noxi-alquinilo para dar el correspondiente alcohol

Country Status (4)

Country Link
US (1) US7402414B2 (es)
AR (1) AR048987A1 (es)
TW (1) TW200602496A (es)
WO (1) WO2005123933A1 (es)

Also Published As

Publication number Publication date
WO2005123933A1 (en) 2005-12-29
TW200602496A (en) 2006-01-16
US20050272725A1 (en) 2005-12-08
US7402414B2 (en) 2008-07-22

Similar Documents

Publication Publication Date Title
WO2009151256A3 (ko) 클로피도크렐 및 그의 유도체의 제조방법
WO2014072785A3 (en) A process for the preparation of pregabalin
ATE535509T1 (de) Verfahren zur herstellung von fettsäurealkylestern und acrolein aus triglyceriden
DE602006021411D1 (de) Verfahren zur herstellung von optional 2-substituierten 1,6-dihydro-6-oxo-4-pyrimidincarboxylsäuren
CO6140053A2 (es) Proceso para fabricar 2-amino-5-halobenzamidas 3-sustituidas
EA201190099A1 (ru) (1-фенил-2-пиридин-4-ил)этиловые эфиры бензойной кислоты в качестве ингибиторов фосфодиэстеразы
EA200870581A1 (ru) Способ превращения нитрильных соединений в карбоновые кислоты и соответствующие эфиры
EA201070649A1 (ru) Смеси алкиловых эфиров жирных кислот и их применение
PL1891189T3 (pl) Zatężanie estrów alkilowych kwasów tłuszczowych w drodze reakcji enzymatycznych z glicerolem
ATE477234T1 (de) Synthese von phenolischen estern von hydroxymethylphenolen
NZ591874A (en) Photosynthetic microorganisms enriched in selenium using selenohydroxy acid compounds, uses thereof in nutrition, cosmetics and pharmacy
AR049668A1 (es) Proceso quimico para preparar esteres de 4,4 - difluorometil - 3 - oxo - butanoico por reaccion entre una amida y un ester.
RU2014122489A (ru) Способы получения гидрогелей с использованием ферментов липаз
ATE514702T1 (de) Verfahren zur herstellung von clopidogrel und dabei verwendete zwischenprodukte
WO2009066642A1 (ja) トリアゾール骨格を有する光応答性塩基
AR048987A1 (es) Proceso enzimatico para desacetilacion de un acetato de fe-noxi-alquinilo para dar el correspondiente alcohol
AR056262A1 (es) Preparacion de alcoholes propargilicos y esteres intermediarios de analogos de himbacina
WO2008093700A1 (ja) トレハロース化合物、その製造方法、及び該化合物を含有する免疫賦活剤
EP4414372A3 (en) Compounds and methods relating to testing for lysosomal storage disorders
RS54082B1 (en) PROCEDURE FOR ENZYMIC SYNTHESIS (7S) -1- (3,4-DIMETOXYBICYCLO [4.2.0] OCTA-1,3,5-TRIEN-7-IL) N-METHYL METHANAMINE AND APPLICATION IN THE SYNTHESIS OF IVABRADINE AND ITS SALTS
HK1142362A1 (en) Polyanion for improved nucleic acid amplification
AR089927A1 (es) Procedimiento de sintesis enzimatica del acido (7s)-3-4-dimetoxibiciclo[4.2.0]octa-1,3,5-trien-7-carboxilico o de sus esteres, y aplicacion a la sintesis de la ivabradina y de sus sales
ATE489355T1 (de) Mandelsäurederivate und deren herstellung
RU2007144740A (ru) Фотосенсибилизатор и способы его получения
EP1840218A4 (en) PROCESS FOR THE SYNTHESIS OF OPTICALLY ACTIVE (S) - OR (R) -BETA-AMINO ACIDS AND OF (S) - OR (R) -BETA-OPTICALLY ACTIVE AMINO ACIDS, 2-ALKOXYETHYL ESTERS OF AMINO ACIDS, AND 2-ALKOXYETHYL ESTERS OF (S) - OR (R)-BETA-AMINO ACIDS

Legal Events

Date Code Title Description
FB Suspension of granting procedure