AR048464A1 - Compuestos con actividad antipsicotica atipica - Google Patents

Compuestos con actividad antipsicotica atipica

Info

Publication number
AR048464A1
AR048464A1 ARP050101325A ARP050101325A AR048464A1 AR 048464 A1 AR048464 A1 AR 048464A1 AR P050101325 A ARP050101325 A AR P050101325A AR P050101325 A ARP050101325 A AR P050101325A AR 048464 A1 AR048464 A1 AR 048464A1
Authority
AR
Argentina
Prior art keywords
alkyl
optionally substituted
atipica
antipsytical
activity
Prior art date
Application number
ARP050101325A
Other languages
English (en)
Inventor
Cesare Maria Assunta Di
Patrizia Minetti
Giuseppe Campiani
Stefania Butini
Original Assignee
Sigma Tau Ind Farmaceuti
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma Tau Ind Farmaceuti filed Critical Sigma Tau Ind Farmaceuti
Publication of AR048464A1 publication Critical patent/AR048464A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

Composiciones farmacéuticas que los contienen y usos. Reivindicacion 1: Un compuesto de formula (1), donde: R es dialquilamina C1-4, donde los grupos alquilo pueden ser iguales o diferentes, 1-piperazinilo opcionalmente sustituido en 4 por alquilo C1-4, siendo dicho grupo alquilo opcionalmente sustituido por un grupo hidroxilo, 1-imidazolilo, 1-piperidinilo opcionalmente sustituido en 4 por un grupo alquilo C1-4; R1 es H o halogeno, Y es CH2, S; los dos X pueden ser independientemente C o N; A es un ciclo aromático con 5 o 6 átomos de carbono; Q es S, CH=, CH-alquiloC1-4; y sus sales farmacéuticamente aceptables.
ARP050101325A 2004-04-07 2005-04-04 Compuestos con actividad antipsicotica atipica AR048464A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT000178A ITRM20040178A1 (it) 2004-04-07 2004-04-07 Composti ad attivita' antipsicotica atipica.

Publications (1)

Publication Number Publication Date
AR048464A1 true AR048464A1 (es) 2006-04-26

Family

ID=34965603

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP050101325A AR048464A1 (es) 2004-04-07 2005-04-04 Compuestos con actividad antipsicotica atipica

Country Status (13)

Country Link
US (1) US20080293689A1 (es)
EP (1) EP1737866A2 (es)
JP (1) JP2007532528A (es)
KR (1) KR20070004747A (es)
CN (1) CN1980931A (es)
AR (1) AR048464A1 (es)
AU (1) AU2005232160A1 (es)
BR (1) BRPI0509648A (es)
CA (1) CA2555859A1 (es)
IT (1) ITRM20040178A1 (es)
MX (1) MXPA06011293A (es)
TW (1) TW200539865A (es)
WO (1) WO2005097797A2 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2650806T3 (es) * 2013-12-11 2018-01-22 Bayer Cropscience Aktiengesellschaft Procedimiento para la preparación de bencilaminas disustituidas halogenadas, particularmente dialquilbencilaminas halogenadas
CN112704678B (zh) * 2020-12-02 2024-02-23 江苏恩华药业股份有限公司 一种丙酰胺衍生物在制备治疗精神分裂症药物中应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4148903A (en) * 1977-07-28 1979-04-10 Merck & Co., Inc. Antipsychotic, antiserotonin and antihistaminic pyrrolo[2,1-b][3]benzazepines
IT1301965B1 (it) * 1998-07-28 2000-07-20 Sigma Tau Ind Farmaceuti Pirrolo (2,1-b)(1,3) benzotiazepine con attivita' antipsicoticaatipica.
IT1317884B1 (it) * 2000-08-01 2003-07-15 Sigma Tau Ind Farmaceuti Pirrolo (2,1-b)(1,3)benzotiazepine e loro uso per la preparazione dimedicamenti ad attivita' antipsicotica classica.

Also Published As

Publication number Publication date
BRPI0509648A (pt) 2007-09-18
CN1980931A (zh) 2007-06-13
TW200539865A (en) 2005-12-16
ITRM20040178A1 (it) 2004-07-07
KR20070004747A (ko) 2007-01-09
WO2005097797A3 (en) 2005-11-10
CA2555859A1 (en) 2005-10-20
US20080293689A1 (en) 2008-11-27
EP1737866A2 (en) 2007-01-03
JP2007532528A (ja) 2007-11-15
WO2005097797A2 (en) 2005-10-20
AU2005232160A1 (en) 2005-10-20
MXPA06011293A (es) 2007-01-16

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