AR046840A1 - Polisacaridos capsulares de neisseria meningitidis como inmunopotenciadores mucosales y formulaciones resultantes - Google Patents

Polisacaridos capsulares de neisseria meningitidis como inmunopotenciadores mucosales y formulaciones resultantes

Info

Publication number
AR046840A1
AR046840A1 ARP040104182A ARP040104182A AR046840A1 AR 046840 A1 AR046840 A1 AR 046840A1 AR P040104182 A ARP040104182 A AR P040104182A AR P040104182 A ARP040104182 A AR P040104182A AR 046840 A1 AR046840 A1 AR 046840A1
Authority
AR
Argentina
Prior art keywords
capsular
polysaccharides
administered
formulations
meningitidis
Prior art date
Application number
ARP040104182A
Other languages
English (en)
Inventor
Feyt Rolando Pajon
Rubido Julio Cesar Aguilar
Perez Olivia Niebla
Portilla Tania Carmenate
Garcia Gretel Sardinas
Espina Maite Delgado
Blanco Sonia Gonzalez
Original Assignee
Ct Ingenieria Genetica Biotech
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ct Ingenieria Genetica Biotech filed Critical Ct Ingenieria Genetica Biotech
Publication of AR046840A1 publication Critical patent/AR046840A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/095—Neisseria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/102—Pasteurellales, e.g. Actinobacillus, Pasteurella; Haemophilus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541—Mucosal route
    • A61K2039/543—Mucosal route intranasal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55583—Polysaccharides

Abstract

Uso de polisacáridos capsulares de distintos serogrupos de Neisseria meningitidis, como agentes inmunopotenciadores e inmunomoduladores, útiles para el desarrollo de vacunas. En el presente se administran dichos polisacáridos para incrementar la respuesta inmune contra antígenos heterólogos que han sido coadministrados por la vía mucosal. Se obtienen formulaciones múltiples de los polisacáridos capsulares de N. meningitidis y antígenos heterólogos que al ser administradas por vías mucosales, producen niveles de inmunogenicidad similares a los obtenidos después de la administración parenteral de combinaciones similares. El uso de dichos polisacáridos como inmunopotenciadores permite prescindir del empleo de otros adyuvantes mucosales. Este uso de los polisacáridos capsulares de N. meningitidis y las formulaciones antigénicas resultantes son aplicables en la industria farmacéutica como formulaciones vacunales preventivas o terapéuticas.
ARP040104182A 2003-11-19 2004-11-12 Polisacaridos capsulares de neisseria meningitidis como inmunopotenciadores mucosales y formulaciones resultantes AR046840A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CU20030270A CU23404A1 (es) 2003-11-19 2003-11-19 Polisacáridos capsulares de neisseria meningitidis como inmunopotenciadores mucosales y formulaciones resultantes

Publications (1)

Publication Number Publication Date
AR046840A1 true AR046840A1 (es) 2005-12-28

Family

ID=34777988

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP040104182A AR046840A1 (es) 2003-11-19 2004-11-12 Polisacaridos capsulares de neisseria meningitidis como inmunopotenciadores mucosales y formulaciones resultantes

Country Status (3)

Country Link
AR (1) AR046840A1 (es)
CU (1) CU23404A1 (es)
WO (1) WO2005049076A1 (es)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR045260A1 (es) 2003-08-12 2005-10-19 3M Innovative Properties Co Compuestos que contienen imidazo-oxima sustituidos
BRPI0413998A (pt) 2003-08-27 2006-11-07 3M Innovative Properties Co imidazoquinolinas arilóxi e arilalquilenóxi substituìdas
AU2004270201A1 (en) 2003-09-05 2005-03-17 3M Innovative Properties Company Treatment for CD5+ B cell lymphoma
US7544697B2 (en) 2003-10-03 2009-06-09 Coley Pharmaceutical Group, Inc. Pyrazolopyridines and analogs thereof
US8871782B2 (en) 2003-10-03 2014-10-28 3M Innovative Properties Company Alkoxy substituted imidazoquinolines
AU2004291101A1 (en) 2003-11-14 2005-06-02 3M Innovative Properties Company Oxime substituted imidazo ring compounds
JP2007511535A (ja) 2003-11-14 2007-05-10 スリーエム イノベイティブ プロパティズ カンパニー ヒドロキシルアミン置換イミダゾ環化合物
MXPA06005910A (es) 2003-11-25 2006-08-23 3M Innovative Properties Co Sistemas de anillo imidazo sustituido y metodos.
EP1701955A1 (en) 2003-12-29 2006-09-20 3M Innovative Properties Company Arylalkenyl and arylalkynyl substituted imidazoquinolines
CA2551399A1 (en) 2003-12-30 2005-07-21 3M Innovative Properties Company Imidazoquinolinyl, imidazopyridinyl, and imidazonaphthyridinyl sulfonamides
AU2005228150A1 (en) 2004-03-24 2005-10-13 3M Innovative Properties Company Amide substituted imidazopyridines, imidazoquinolines, and imidazonaphthyridines
WO2005123080A2 (en) 2004-06-15 2005-12-29 3M Innovative Properties Company Nitrogen-containing heterocyclyl substituted imidazoquinolines and imidazonaphthyridines
US8026366B2 (en) 2004-06-18 2011-09-27 3M Innovative Properties Company Aryloxy and arylalkyleneoxy substituted thiazoloquinolines and thiazolonaphthyridines
US7897609B2 (en) 2004-06-18 2011-03-01 3M Innovative Properties Company Aryl substituted imidazonaphthyridines
WO2006065280A2 (en) 2004-06-18 2006-06-22 3M Innovative Properties Company Isoxazole, dihydroisoxazole, and oxadiazole substituted imidazo ring compounds and methods
AU2005326708C1 (en) 2004-12-30 2012-08-30 3M Innovative Properties Company Substituted chiral fused [1,2]imidazo[4,5-c] ring compounds
CA2592904C (en) 2004-12-30 2015-04-07 3M Innovative Properties Company Chiral fused [1,2]imidazo[4,5-c] ring compounds
JP2008526757A (ja) * 2004-12-30 2008-07-24 スリーエム イノベイティブ プロパティズ カンパニー 免疫応答調節剤製剤および方法
CA2597092A1 (en) 2005-02-04 2006-08-10 Coley Pharmaceutical Group, Inc. Aqueous gel formulations containing immune reponse modifiers
WO2006086634A2 (en) 2005-02-11 2006-08-17 Coley Pharmaceutical Group, Inc. Oxime and hydroxylamine substituted imidazo[4,5-c] ring compounds and methods
WO2006107851A1 (en) 2005-04-01 2006-10-12 Coley Pharmaceutical Group, Inc. 1-substituted pyrazolo (3,4-c) ring compounds as modulators of cytokine biosynthesis for the treatment of viral infections and neoplastic diseases
US7943610B2 (en) 2005-04-01 2011-05-17 3M Innovative Properties Company Pyrazolopyridine-1,4-diamines and analogs thereof
US7906506B2 (en) 2006-07-12 2011-03-15 3M Innovative Properties Company Substituted chiral fused [1,2] imidazo [4,5-c] ring compounds and methods
CN101785857B (zh) * 2010-03-05 2012-09-26 成都安特金生物技术有限公司 一种新的肺炎球菌结合疫苗及其制备方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ20024224A3 (cs) * 2000-06-29 2003-05-14 Glaxosmithkline Biologicals S. A. Farmaceutický prostředek

Also Published As

Publication number Publication date
CU23404A1 (es) 2009-08-04
WO2005049076A1 (es) 2005-06-02

Similar Documents

Publication Publication Date Title
AR046840A1 (es) Polisacaridos capsulares de neisseria meningitidis como inmunopotenciadores mucosales y formulaciones resultantes
CY1115308T1 (el) Συνθεσεις εμβολιου οι οποιες περιεχουν ανοσοενισχυτικο εκδοχο σαπωνινης
DE122011100053I1 (de) Influenza vakzinzusammensetzungen zur intradermaler verabreichung.
TW200722101A (en) Novel composition
CO6270339A2 (es) Formulaciones de vacuna meningococica
PT1187629E (pt) Composicao adjuvante que compreende saponina e um oligonucleotido imunoestimulador
EP3058954A3 (en) Immunogenic compositions and methods
NO20064781L (no) Fremgangsmater og adjuvanser for a forbedre immunresponser mot vaksiner og fremgangsmater for anvendelse
AR035586A1 (es) Composicion de vacuna, equipo, metodos para incrementar la respuesta inmune, uso de un derivado de 1h-imidazo(4,5-c)quinolin-4-amina en la fabricacion de un medicamento, y combinacion de componentes para la administracion separada, secuencial o concomitante para el uso en la vacunacion de adn
CY1111916T1 (el) Εμβολιο ζωντανου εξασθενημενου ροταϊου για χορηγηση απο του στοματος
UY27843A1 (es) Composicion de vacuna
PE20190458A1 (es) Composiciones de neisseria meningitidis y metodos de las mismas
AR102548A1 (es) Vacunas contra la enfermedad de manos, pies y boca y métodos de fabricación y uso
AR053661A1 (es) Peptido para entregar vacunas via mucosas
AR038311A1 (es) Antigeno de superficie del virus de la hepatitis b como inmunopotenciador mucosal, formulaciones resultantes
AR059972A1 (es) Administracion intranasal o inhalacional de virosomas
BRPI0418332A (pt) adjuvantes vacinais, formulação vacinal, uso da formulação vacinal e esquema de imunização
AR046921A1 (es) Metodo para la incorporacion de antigenos en vesiculas de membrana externa de bacterias y formulaciones resultantes
SG160386A1 (en) Novel composition
UY27621A1 (es) " antígeno de superficie del virus de la hepatitis b como inmunopotenciador mucosal, formulaciones resultantes"
AR088365A1 (es) Adjuvantes para vacunas polisacaridicas y las formulaciones resultantes
CY1115921T1 (el) Εμβολιο γριπης
CU20110202A7 (es) Composición inmunogénica de polisacáridos planos adyuvados y las formulaciones resultantes
TH75448A (th) พอลิแซคคาไรด์ที่เป็นปลอกหุ้มของ Neisseria meningitidis ในการเป็นตัวกระตุ้นภูมิคุ้มกันทางเยื่อบุเมือก และสูตรผสมผลลัพธ์ที่ได้
TH62589A (th) แอนติเจนที่ผิวของไวรัสตับอักเสบ b ที่เป็นตัวเสริมภูมิคุ้มกันที่เยื่อเมือก, สารผสมตามสูตรที่ได้

Legal Events

Date Code Title Description
FB Suspension of granting procedure