AR043831A1 - Derivados de pirrodilina y procedimiento para prepararlos - Google Patents
Derivados de pirrodilina y procedimiento para prepararlosInfo
- Publication number
- AR043831A1 AR043831A1 ARP040101113A ARP040101113A AR043831A1 AR 043831 A1 AR043831 A1 AR 043831A1 AR P040101113 A ARP040101113 A AR P040101113A AR P040101113 A ARP040101113 A AR P040101113A AR 043831 A1 AR043831 A1 AR 043831A1
- Authority
- AR
- Argentina
- Prior art keywords
- oxo
- formula
- compound
- imino
- hal
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10315377A DE10315377A1 (de) | 2003-04-03 | 2003-04-03 | Carbonylverbindungen |
| DE10327428A DE10327428A1 (de) | 2003-06-18 | 2003-06-18 | Ethinylprolinderivate |
| DE2003129295 DE10329295A1 (de) | 2003-06-30 | 2003-06-30 | Carbonylverbindungen |
| DE10329457A DE10329457A1 (de) | 2003-04-03 | 2003-07-01 | Ethinylprolinderivate |
| DE2003134174 DE10334174A1 (de) | 2003-07-26 | 2003-07-26 | Pyrrolidinderivate und Verfahren zur Herstellung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR043831A1 true AR043831A1 (es) | 2005-08-17 |
Family
ID=33136213
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP040101113A AR043831A1 (es) | 2003-04-03 | 2004-04-02 | Derivados de pirrodilina y procedimiento para prepararlos |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US7504500B2 (enExample) |
| EP (1) | EP1608646B1 (enExample) |
| JP (1) | JP4634369B2 (enExample) |
| KR (1) | KR20050118709A (enExample) |
| AR (1) | AR043831A1 (enExample) |
| AT (1) | ATE366732T1 (enExample) |
| AU (1) | AU2004226280B2 (enExample) |
| BR (1) | BRPI0408888A (enExample) |
| CA (1) | CA2520893C (enExample) |
| DE (2) | DE10329457A1 (enExample) |
| ES (1) | ES2287708T3 (enExample) |
| MX (1) | MXPA05010433A (enExample) |
| PE (1) | PE20050395A1 (enExample) |
| PL (1) | PL377138A1 (enExample) |
| TW (1) | TW200500339A (enExample) |
| WO (1) | WO2004087695A1 (enExample) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050119266A1 (en) * | 2003-10-01 | 2005-06-02 | Yan Shi | Pyrrolidine and piperidine derivatives as factor Xa inhibitors |
| DE102004004731A1 (de) * | 2004-01-30 | 2005-08-18 | Merck Patent Gmbh | Harnstoffderivate |
| DE102004045796A1 (de) * | 2004-09-22 | 2006-03-23 | Merck Patent Gmbh | Arzneimittel enthaltend Carbonylverbindungen sowie deren Verwendung |
| DE102004047254A1 (de) * | 2004-09-29 | 2006-04-13 | Merck Patent Gmbh | Carbonylverbindungen |
| DE102004050283A1 (de) * | 2004-10-15 | 2006-04-27 | Lanxess Deutschland Gmbh | 4-Aminophenyl-morpholinon-Derivate und deren Herstellung |
| US7301817B2 (en) | 2005-10-27 | 2007-11-27 | Sandisk Corporation | Method for programming of multi-state non-volatile memory using smart verify |
| KR101020440B1 (ko) * | 2005-11-16 | 2011-03-08 | 에프. 호프만-라 로슈 아게 | 응고 인자 Ｘａ의 억제제로서의 피롤리딘 유도체 |
| EP1818330A1 (de) * | 2006-02-14 | 2007-08-15 | Boehringer Ingelheim Pharma GmbH & Co.KG | Substituierte Prolinamide, deren Herstellung und deren Verwendung als Arzneimittel |
| JP5263686B2 (ja) | 2006-05-16 | 2013-08-14 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 置換プロリンアミド、その製造及び薬物としての使用 |
| US8673920B2 (en) | 2009-05-06 | 2014-03-18 | Merck Sharp & Dohme Corp. | Inhibitors of the renal outer medullary potassium channel |
| EP2632465B1 (en) | 2010-10-27 | 2015-12-30 | Merck Sharp & Dohme Corp. | Inhibitors of the renal outer medullary potassium channel |
| WO2012058134A1 (en) | 2010-10-29 | 2012-05-03 | Merck Sharp & Dohme Corp. | Inhibitors of the renal outer medullary potassium channel |
| CA2844310A1 (en) | 2011-08-19 | 2013-02-28 | Merck Sharp & Dohme Corp. | Inhibitors of the renal outer medullary potassium channel |
| TW201317213A (zh) | 2011-09-16 | 2013-05-01 | Merck Sharp & Dohme | 腎外髓質鉀通道抑制劑 |
| EP2771005B1 (en) | 2011-10-25 | 2016-05-18 | Merck Sharp & Dohme Corp. | Inhibitors of the renal outer medullary potassium channel |
| WO2013062900A1 (en) | 2011-10-25 | 2013-05-02 | Merck Sharp & Dohme Corp. | Inhibitors of the renal outer medullary potassium channel |
| EP2773351B1 (en) | 2011-10-31 | 2017-08-23 | Merck Sharp & Dohme Corp. | Inhibitors of the renal outer medullary potassium channel |
| US9108947B2 (en) | 2011-10-31 | 2015-08-18 | Merck Sharp & Dohme Corp. | Inhibitors of the Renal Outer Medullary Potassium channel |
| US9139585B2 (en) | 2011-10-31 | 2015-09-22 | Merck Sharp & Dohme Corp. | Inhibitors of the Renal Outer Medullary Potassium channel |
| WO2013090271A1 (en) | 2011-12-16 | 2013-06-20 | Merck Sharp & Dohme Corp. | Inhibitors of the renal outer medullary potassium channel |
| AR092031A1 (es) | 2012-07-26 | 2015-03-18 | Merck Sharp & Dohme | Inhibidores del canal de potasio medular externo renal |
| WO2014085210A1 (en) | 2012-11-29 | 2014-06-05 | Merck Sharp & Dohme Corp. | Inhibitors of the renal outer medullary potassium channel |
| WO2014099633A2 (en) | 2012-12-19 | 2014-06-26 | Merck Sharp & Dohme Corp. | Inhibitors of the renal outer medullary potassium channel |
| EP2956142B1 (en) | 2013-02-18 | 2017-09-20 | Merck Sharp & Dohme Corp. | Inhibitors of the renal outer medullary potassium channel |
| EP2968288B1 (en) | 2013-03-15 | 2018-07-04 | Merck Sharp & Dohme Corp. | Inhibitors of the renal outer medullary potassium channel |
| WO2015017305A1 (en) | 2013-07-31 | 2015-02-05 | Merck Sharp & Dohme Corp | Inhibitors of the renal outer medullary potassium channel |
| WO2015065866A1 (en) | 2013-10-31 | 2015-05-07 | Merck Sharp & Dohme Corp. | Inhibitors of the renal outer medullary potassium channel |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5822111B2 (ja) | 1977-10-29 | 1983-05-06 | 協和醗酵工業株式会社 | 柑橘類果実の改質剤 |
| JPS63232846A (ja) | 1987-03-20 | 1988-09-28 | Haruo Ogura | 新規な固定相担体 |
| WO1998022432A1 (en) * | 1996-11-18 | 1998-05-28 | Yamanouchi Pharmaceutical Co., Ltd. | Novel acylamino-substituted acylanilide derivatives or pharmaceutical composition comprising the same |
| US7030141B2 (en) * | 2001-11-29 | 2006-04-18 | Christopher Franklin Bigge | Inhibitors of factor Xa and other serine proteases involved in the coagulation cascade |
-
2003
- 2003-07-01 DE DE10329457A patent/DE10329457A1/de not_active Withdrawn
-
2004
- 2004-03-09 EP EP04718646A patent/EP1608646B1/de not_active Expired - Lifetime
- 2004-03-09 DE DE502004004294T patent/DE502004004294D1/de not_active Expired - Lifetime
- 2004-03-09 CA CA2520893A patent/CA2520893C/en not_active Expired - Fee Related
- 2004-03-09 AU AU2004226280A patent/AU2004226280B2/en not_active Ceased
- 2004-03-09 JP JP2006504602A patent/JP4634369B2/ja not_active Expired - Fee Related
- 2004-03-09 AT AT04718646T patent/ATE366732T1/de not_active IP Right Cessation
- 2004-03-09 PL PL377138A patent/PL377138A1/pl unknown
- 2004-03-09 ES ES04718646T patent/ES2287708T3/es not_active Expired - Lifetime
- 2004-03-09 MX MXPA05010433A patent/MXPA05010433A/es not_active Application Discontinuation
- 2004-03-09 BR BRPI0408888-3A patent/BRPI0408888A/pt not_active Application Discontinuation
- 2004-03-09 US US10/551,670 patent/US7504500B2/en not_active Expired - Fee Related
- 2004-03-09 WO PCT/EP2004/002405 patent/WO2004087695A1/de not_active Ceased
- 2004-03-09 KR KR1020057018640A patent/KR20050118709A/ko not_active Withdrawn
- 2004-03-31 TW TW093108904A patent/TW200500339A/zh unknown
- 2004-04-02 PE PE2004000349A patent/PE20050395A1/es not_active Application Discontinuation
- 2004-04-02 AR ARP040101113A patent/AR043831A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU2004226280A1 (en) | 2004-10-14 |
| PE20050395A1 (es) | 2005-06-04 |
| US20060211692A1 (en) | 2006-09-21 |
| KR20050118709A (ko) | 2005-12-19 |
| EP1608646A1 (de) | 2005-12-28 |
| PL377138A1 (pl) | 2006-01-23 |
| AU2004226280B2 (en) | 2010-06-17 |
| TW200500339A (en) | 2005-01-01 |
| ATE366732T1 (de) | 2007-08-15 |
| CA2520893C (en) | 2012-07-10 |
| MXPA05010433A (es) | 2005-11-04 |
| ES2287708T3 (es) | 2007-12-16 |
| JP4634369B2 (ja) | 2011-02-16 |
| BRPI0408888A (pt) | 2006-04-11 |
| DE10329457A1 (de) | 2005-01-20 |
| JP2006522037A (ja) | 2006-09-28 |
| WO2004087695A1 (de) | 2004-10-14 |
| CA2520893A1 (en) | 2004-10-14 |
| US7504500B2 (en) | 2009-03-17 |
| EP1608646B1 (de) | 2007-07-11 |
| DE502004004294D1 (de) | 2007-08-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |