AR042917A1 - Dispositivo de liberacion sostenida para la administracion ocular de agentes adrenergicos y uso de agentes adrenergicos para su preparacion - Google Patents
Dispositivo de liberacion sostenida para la administracion ocular de agentes adrenergicos y uso de agentes adrenergicos para su preparacionInfo
- Publication number
- AR042917A1 AR042917A1 ARP040100201A ARP040100201A AR042917A1 AR 042917 A1 AR042917 A1 AR 042917A1 AR P040100201 A ARP040100201 A AR P040100201A AR P040100201 A ARP040100201 A AR P040100201A AR 042917 A1 AR042917 A1 AR 042917A1
- Authority
- AR
- Argentina
- Prior art keywords
- adrenergic
- sustained release
- adrenergic agents
- adrenergic agent
- agents
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0092—Hollow drug-filled fibres, tubes of the core-shell type, coated fibres, coated rods, microtubules or nanotubes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/382—Heterocyclic compounds having sulfur as a ring hetero atom having six-membered rings, e.g. thioxanthenes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
- A61K9/0051—Ocular inserts, ocular implants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/28—Materials for coating prostheses
- A61L27/34—Macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/54—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/432—Inhibitors, antagonists
- A61L2300/434—Inhibitors, antagonists of enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
- A61L2300/606—Coatings
- A61L2300/608—Coatings having two or more layers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/16—Materials or treatment for tissue regeneration for reconstruction of eye parts, e.g. intraocular lens, cornea
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Ophthalmology & Optometry (AREA)
- Dermatology (AREA)
- Biomedical Technology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Molecular Biology (AREA)
- Surgery (AREA)
- Neurosurgery (AREA)
- Emergency Medicine (AREA)
- Nanotechnology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
La presente provee un dispositivo para tratar y/o prevenir la presión intraocular elevada, tal como la asociada con el glaucoma o el uso de corticosteroides, con agentes adrenérgicos. La presente provee dispositivos de liberación sostenida insertables adaptados para mantener una concentración terapéuticamente eficaz de uno o más agentes adrenérgicos durante un período de tiempo prolongado, y el uso de los agentes adrenérgicos para la preparación del dispositivo de liberación sostenida. Reivindicación 1: Un dispositivo para fármaco de liberación sostenida adaptado para la implantación en o adyacente al ojo de un paciente, comprendiendo el dispositivo de administración del fármaco: i) un núcleo de fármaco interior que comprende un agente adrenérgico; ii) un primer recubrimiento sobre la superficie del núcleo del fármaco, que es sustancialmente impermeable al pasaje del agente adrenérgico, que tiene una o más aberturas en el mismo que permiten la difusión del agente adrenérgico, y que es sustancialmente insoluble e inerte en los fluidos corporales y compatible con los tejidos corporales; y iii) uno o más recubrimientos adicionales que son permeables al pasaje del agente adrenérgico, y que son sustancialmente insolubles e inertes en los fluidos corporales y compatibles con los tejidos corporales; donde los recubrimientos primero y adicionales están dispuestos cerca del núcleo de fármaco interior para producir, cuando están implantados, una velocidad de liberación sustancialmente constante del agente adrenérgico del dispositivo.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US44249903P | 2003-01-24 | 2003-01-24 | |
US48267703P | 2003-06-26 | 2003-06-26 | |
US48331603P | 2003-06-26 | 2003-06-26 | |
US50197403P | 2003-09-11 | 2003-09-11 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR042917A1 true AR042917A1 (es) | 2005-07-06 |
Family
ID=32831098
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP040100201A AR042917A1 (es) | 2003-01-24 | 2004-01-23 | Dispositivo de liberacion sostenida para la administracion ocular de agentes adrenergicos y uso de agentes adrenergicos para su preparacion |
Country Status (15)
Country | Link |
---|---|
EP (1) | EP1592408B1 (es) |
JP (1) | JP2006516618A (es) |
KR (1) | KR20050118161A (es) |
AR (1) | AR042917A1 (es) |
AT (1) | ATE440595T1 (es) |
AU (1) | AU2004207506B2 (es) |
BR (1) | BRPI0406879B1 (es) |
CA (1) | CA2513751C (es) |
DE (1) | DE602004022776D1 (es) |
DK (1) | DK1592408T3 (es) |
ES (1) | ES2332720T3 (es) |
MX (1) | MXPA05007719A (es) |
SI (1) | SI1592408T1 (es) |
TW (1) | TWI356714B (es) |
WO (1) | WO2004066979A2 (es) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AR043356A1 (es) * | 2003-01-24 | 2005-07-27 | Control Delivery Sys Inc | Dispositvo de liberacion sostenida para la administracion ocular de inhibidores de la anhidrasa carbonica y uso de inhibidores de la anhidrasa carbonica para su preparacion |
US8425929B2 (en) * | 2004-04-30 | 2013-04-23 | Allergan, Inc. | Sustained release intraocular implants and methods for preventing retinal dysfunction |
US20050244463A1 (en) * | 2004-04-30 | 2005-11-03 | Allergan, Inc. | Sustained release intraocular implants and methods for treating ocular vasculopathies |
US7922702B2 (en) | 2004-07-02 | 2011-04-12 | Qlt Inc. | Treatment medium delivery device and methods for delivery of such treatment mediums to the eye using such a delivery device |
US8795711B2 (en) * | 2006-03-31 | 2014-08-05 | Mati Therapeutics Inc. | Drug delivery methods, structures, and compositions for nasolacrimal system |
CN101505696B (zh) * | 2006-06-21 | 2012-11-14 | 庄臣及庄臣视力保护公司 | 用于递送活性试剂的泪点塞 |
US9173773B2 (en) | 2006-06-21 | 2015-11-03 | Johnson & Johnson Vision Care, Inc. | Punctal plugs for the delivery of active agents |
FR2906712A1 (fr) * | 2006-10-09 | 2008-04-11 | France Chirurgie Instr | Bouchon meatique a pose simplifiee. |
AU2007339929A1 (en) * | 2006-12-26 | 2008-07-10 | Qlt Inc. | Drug delivery implants for inhibition of optical defects |
DK2207529T3 (en) * | 2007-09-07 | 2015-03-09 | Mati Therapeutics Inc | PHARMACEUTICAL cores for the sustained release of therapeutic agents |
KR20100050566A (ko) * | 2007-09-07 | 2010-05-13 | 큐엘티 플러그 딜리버리, 인코포레이티드 | 눈물 임플랜트 및 이에 관련된 방법 |
US20090264477A1 (en) * | 2008-04-18 | 2009-10-22 | Warsaw Orthopedic, Inc., An Indiana Corporation | Beta adrenergic receptor agonists for treatment of pain and/or inflammation |
JP2011520805A (ja) * | 2008-05-09 | 2011-07-21 | キューエルティー プラグ デリバリー,インク. | 緑内障および高眼圧症治療のための活性剤の持続送達 |
US10064819B2 (en) | 2008-05-12 | 2018-09-04 | University Of Utah Research Foundation | Intraocular drug delivery device and associated methods |
TW201012469A (en) * | 2008-06-24 | 2010-04-01 | Qlt Plug Delivery Inc | Combination treatment of glaucoma |
US9095506B2 (en) | 2008-11-17 | 2015-08-04 | Allergan, Inc. | Biodegradable alpha-2 agonist polymeric implants and therapeutic uses thereof |
WO2010071844A1 (en) * | 2008-12-19 | 2010-06-24 | Qlt Plug Delivery, Inc | Substance delivering punctum implants and methods |
JP2012514493A (ja) * | 2009-01-02 | 2012-06-28 | アルコン リサーチ, リミテッド | その場で再充填可能な眼用移植物 |
KR101769637B1 (ko) | 2009-11-09 | 2017-08-18 | 알러간, 인코포레이티드 | 모발 성장을 촉진하기 위한 조성물 및 방법 |
JP2013523821A (ja) * | 2010-04-06 | 2013-06-17 | アラーガン、インコーポレイテッド | 前房内薬剤送達のための徐放性リザーバーインプラント |
US8349005B2 (en) | 2011-01-03 | 2013-01-08 | Masatoshi Murata | Method for burying implant to choroid |
WO2013011511A1 (en) | 2011-07-18 | 2013-01-24 | Mor Research Applications Ltd. | A device for adjusting the intraocular pressure |
BR112015019546A2 (pt) | 2013-02-15 | 2017-07-18 | Allergan Inc | implante de distribuição de drogas prolongado |
JP7278223B2 (ja) * | 2017-06-13 | 2023-05-19 | アイポイント ファーマシューティカルズ,インコーポレイティド | 生体浸食性薬物送達デバイス |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5378475A (en) * | 1991-02-21 | 1995-01-03 | University Of Kentucky Research Foundation | Sustained release drug delivery devices |
US5902598A (en) * | 1997-08-28 | 1999-05-11 | Control Delivery Systems, Inc. | Sustained release drug delivery devices |
US6196993B1 (en) * | 1998-04-20 | 2001-03-06 | Eyelab Group, Llc | Ophthalmic insert and method for sustained release of medication to the eye |
US6375972B1 (en) * | 2000-04-26 | 2002-04-23 | Control Delivery Systems, Inc. | Sustained release drug delivery devices, methods of use, and methods of manufacturing thereof |
-
2004
- 2004-01-23 ES ES04704837T patent/ES2332720T3/es not_active Expired - Lifetime
- 2004-01-23 AU AU2004207506A patent/AU2004207506B2/en not_active Ceased
- 2004-01-23 DE DE602004022776T patent/DE602004022776D1/de not_active Expired - Lifetime
- 2004-01-23 JP JP2006502933A patent/JP2006516618A/ja active Pending
- 2004-01-23 AT AT04704837T patent/ATE440595T1/de not_active IP Right Cessation
- 2004-01-23 SI SI200431291T patent/SI1592408T1/sl unknown
- 2004-01-23 CA CA2513751A patent/CA2513751C/en not_active Expired - Fee Related
- 2004-01-23 EP EP04704837A patent/EP1592408B1/en not_active Expired - Lifetime
- 2004-01-23 AR ARP040100201A patent/AR042917A1/es unknown
- 2004-01-23 KR KR1020057013643A patent/KR20050118161A/ko not_active Application Discontinuation
- 2004-01-23 WO PCT/US2004/001718 patent/WO2004066979A2/en active Application Filing
- 2004-01-23 BR BRPI0406879A patent/BRPI0406879B1/pt not_active IP Right Cessation
- 2004-01-23 MX MXPA05007719A patent/MXPA05007719A/es active IP Right Grant
- 2004-01-23 DK DK04704837T patent/DK1592408T3/da active
- 2004-01-27 TW TW093101751A patent/TWI356714B/zh not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
BRPI0406879B1 (pt) | 2015-12-22 |
SI1592408T1 (sl) | 2010-01-29 |
EP1592408B1 (en) | 2009-08-26 |
AU2004207506A1 (en) | 2004-08-12 |
DK1592408T3 (da) | 2010-01-04 |
ES2332720T3 (es) | 2010-02-11 |
TWI356714B (en) | 2012-01-21 |
BRPI0406879A (pt) | 2006-01-03 |
KR20050118161A (ko) | 2005-12-15 |
CA2513751A1 (en) | 2004-08-12 |
TW200500099A (en) | 2005-01-01 |
EP1592408A2 (en) | 2005-11-09 |
ATE440595T1 (de) | 2009-09-15 |
JP2006516618A (ja) | 2006-07-06 |
DE602004022776D1 (de) | 2009-10-08 |
AU2004207506B2 (en) | 2009-10-08 |
MXPA05007719A (es) | 2005-09-30 |
WO2004066979A2 (en) | 2004-08-12 |
CA2513751C (en) | 2012-01-10 |
WO2004066979A3 (en) | 2004-09-16 |
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Legal Events
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