AR037760A1 - Comprimido matricial con recubrimiento pelicular con liberacion controlada de una mezcla natural de estrogenos conjugados obtenidos a partir de la orina de yeguas prenadas y su procedimiento de preparacion. - Google Patents
Comprimido matricial con recubrimiento pelicular con liberacion controlada de una mezcla natural de estrogenos conjugados obtenidos a partir de la orina de yeguas prenadas y su procedimiento de preparacion.Info
- Publication number
- AR037760A1 AR037760A1 ARP020104765A ARP020104765A AR037760A1 AR 037760 A1 AR037760 A1 AR 037760A1 AR P020104765 A ARP020104765 A AR P020104765A AR P020104765 A ARP020104765 A AR P020104765A AR 037760 A1 AR037760 A1 AR 037760A1
- Authority
- AR
- Argentina
- Prior art keywords
- pharmaceutical
- matrix
- group
- mixture
- active substance
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 6
- 238000013270 controlled release Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 210000002700 urine Anatomy 0.000 title 1
- 239000011159 matrix material Substances 0.000 abstract 5
- 229920000168 Microcrystalline cellulose Polymers 0.000 abstract 3
- 239000013543 active substance Substances 0.000 abstract 3
- 235000019813 microcrystalline cellulose Nutrition 0.000 abstract 3
- 241000283073 Equus caballus Species 0.000 abstract 2
- 229940011871 estrogen Drugs 0.000 abstract 2
- 239000000262 estrogen Substances 0.000 abstract 2
- 239000007888 film coating Substances 0.000 abstract 2
- 238000009501 film coating Methods 0.000 abstract 2
- 229920003168 pharmaceutical polymer Polymers 0.000 abstract 2
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 abstract 1
- 229920000881 Modified starch Polymers 0.000 abstract 1
- 239000003831 antifriction material Substances 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 239000011230 binding agent Substances 0.000 abstract 1
- 229920002678 cellulose Polymers 0.000 abstract 1
- 235000010980 cellulose Nutrition 0.000 abstract 1
- 239000001913 cellulose Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 230000006835 compression Effects 0.000 abstract 1
- 238000007906 compression Methods 0.000 abstract 1
- 230000003111 delayed effect Effects 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 238000001035 drying Methods 0.000 abstract 1
- 239000000945 filler Substances 0.000 abstract 1
- -1 flow regulators Substances 0.000 abstract 1
- 230000003054 hormonal effect Effects 0.000 abstract 1
- 229920001477 hydrophilic polymer Polymers 0.000 abstract 1
- 230000002209 hydrophobic effect Effects 0.000 abstract 1
- 239000008101 lactose Substances 0.000 abstract 1
- 239000000314 lubricant Substances 0.000 abstract 1
- 239000013563 matrix tablet Substances 0.000 abstract 1
- 239000008108 microcrystalline cellulose Substances 0.000 abstract 1
- 229940016286 microcrystalline cellulose Drugs 0.000 abstract 1
- 235000019426 modified starch Nutrition 0.000 abstract 1
- 239000002357 osmotic agent Substances 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 239000004014 plasticizer Substances 0.000 abstract 1
- 239000011148 porous material Substances 0.000 abstract 1
- 238000005507 spraying Methods 0.000 abstract 1
- 239000003826 tablet Substances 0.000 abstract 1
- 239000003981 vehicle Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
- A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/30—Oestrogens
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Biophysics (AREA)
- Endocrinology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Reproductive Health (AREA)
- Diabetes (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP01129830 | 2001-12-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR037760A1 true AR037760A1 (es) | 2004-12-01 |
Family
ID=8179548
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP020104765A AR037760A1 (es) | 2001-12-14 | 2002-12-09 | Comprimido matricial con recubrimiento pelicular con liberacion controlada de una mezcla natural de estrogenos conjugados obtenidos a partir de la orina de yeguas prenadas y su procedimiento de preparacion. |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US8268351B2 (https=) |
| EP (1) | EP1465602B1 (https=) |
| JP (1) | JP4695837B2 (https=) |
| CN (1) | CN100542538C (https=) |
| AR (1) | AR037760A1 (https=) |
| AT (1) | ATE438384T1 (https=) |
| AU (1) | AU2002361396B2 (https=) |
| BR (1) | BR0215044A (https=) |
| CA (1) | CA2470207C (https=) |
| DE (1) | DE50213751D1 (https=) |
| DK (1) | DK1465602T3 (https=) |
| ES (1) | ES2328910T3 (https=) |
| MX (1) | MXPA04005769A (https=) |
| PL (1) | PL205739B1 (https=) |
| PT (1) | PT1465602E (https=) |
| SI (1) | SI1465602T1 (https=) |
| TW (1) | TWI252111B (https=) |
| WO (1) | WO2003051336A1 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7303763B2 (en) * | 2001-02-12 | 2007-12-04 | Watson Laboratories, Inc. | Compositions for conjugated estrogens and associated methods |
| CA2476201C (en) * | 2002-02-21 | 2009-09-01 | Biovail Laboratories Incorporated | Modified release formulations of at least one form of tramadol |
| US8323692B2 (en) | 2002-02-21 | 2012-12-04 | Valeant International Bermuda | Controlled release dosage forms |
| US6992075B2 (en) * | 2003-04-04 | 2006-01-31 | Barr Laboratories, Inc. | C(14) estrogenic compounds |
| GB0329498D0 (en) * | 2003-12-19 | 2004-01-28 | Novartis Ag | Organic compounds |
| JP4521554B2 (ja) * | 2004-03-31 | 2010-08-11 | マイラン製薬株式会社 | シクロスポリン製剤 |
| DE102004035938A1 (de) * | 2004-07-23 | 2006-02-16 | Röhm GmbH & Co. KG | Verfahren zur Herstellung von überzogenen Arzneiformen mit stabilem Wirkstofffreigabeprofil |
| EP1679065A1 (en) | 2005-01-07 | 2006-07-12 | OctoPlus Sciences B.V. | Controlled release compositions for interferon based on PEGT/PBT block copolymers |
| JP5162141B2 (ja) * | 2007-02-20 | 2013-03-13 | エスエス製薬株式会社 | フィルムコーティング用組成物 |
| JP4864024B2 (ja) * | 2008-02-15 | 2012-01-25 | エスエス製薬株式会社 | 時限放出製剤 |
| US20090232897A1 (en) * | 2008-03-14 | 2009-09-17 | Bijayananda Sahoo | Pharmaceutical compositions comprising conjugated estrogens |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3753767A (en) * | 1971-08-02 | 1973-08-21 | Colgate Palmolive Co | Method of sugar-coating tablets |
| DE3535536A1 (de) * | 1985-10-04 | 1987-04-09 | Lentia Gmbh | Verfahren zum gleichzeitigen trocknen und granulieren von extraktstoffen aus enteiweisstem kaelberblut |
| US5208225A (en) * | 1986-02-27 | 1993-05-04 | Warner-Lambert Company | Compositions containing fixed combinations |
| US5108995A (en) * | 1987-09-24 | 1992-04-28 | Jencap Research Ltd. | Hormone preparation and method |
| EP0322020A1 (en) * | 1987-12-22 | 1989-06-28 | Akzo N.V. | Pharmaceutical dosage unit for treating climacteric complaints and osteoporosis |
| HU9500322D0 (en) * | 1994-02-08 | 1995-03-28 | Solvay Deutschland | Process for separating estrogenes from the urine of mares with foal |
| US5458887A (en) * | 1994-03-02 | 1995-10-17 | Andrx Pharmaceuticals, Inc. | Controlled release tablet formulation |
| DE4447714C2 (de) * | 1994-08-09 | 1998-02-05 | Jenapharm Gmbh | Verwendung von Estra-1,3,5(10)-trien-Derivaten zur Hormonsubstitutions-Therapie |
| IE80467B1 (en) * | 1995-07-03 | 1998-07-29 | Elan Corp Plc | Controlled release formulations for poorly soluble drugs |
| WO1997004752A1 (en) * | 1995-07-26 | 1997-02-13 | Duramed Pharmaceuticals, Inc. | Pharmaceutical compositions of conjugated estrogens and methods for their use |
| DE19540253C2 (de) * | 1995-10-28 | 1998-06-04 | Jenapharm Gmbh | Mehrphasenpräparat zur Kontrazeption auf der Basis natürlicher Estrogene |
| CN1101683C (zh) * | 1996-08-30 | 2003-02-19 | 索尔瓦药物有限公司 | 由牝马尿获取雌激素的方法 |
| CN1101682C (zh) * | 1996-08-30 | 2003-02-19 | 索尔瓦药物有限公司 | 由牝马尿液获取雌激素的方法 |
| DE59610985D1 (de) | 1996-08-30 | 2004-05-19 | Solvay Pharm Gmbh | Verfahren zur gewinnung von oestrogenen aus stutenharn |
| HU228765B1 (hu) | 1996-08-30 | 2013-05-28 | Abbott Products Gmbh | Eljárás ösztrogének kinyerésére kancavizeletbõl |
| PT1003476E (pt) * | 1997-08-11 | 2005-05-31 | Alza Corp | Forma de dosagem de agente activo de libertacao prolongada adaptada para retencao gastrica |
| US6022554A (en) * | 1997-12-15 | 2000-02-08 | American Home Products Corporation | Polymeric microporous film coated subcutaneous implant |
| DE19845358A1 (de) * | 1998-10-02 | 2000-04-06 | Roehm Gmbh | Überzogene Arzneiformen mit kontrollierter Wirkstoffabgabe |
| ATE433318T1 (de) * | 1999-02-10 | 2009-06-15 | Pfizer Prod Inc | Osmotisches system zur verabreichung von wirkstoffen, die feste amorphe dispersionen enthalten |
| US6706283B1 (en) * | 1999-02-10 | 2004-03-16 | Pfizer Inc | Controlled release by extrusion of solid amorphous dispersions of drugs |
| US6632451B2 (en) * | 1999-06-04 | 2003-10-14 | Dexcel Pharma Technologies Ltd. | Delayed total release two pulse gastrointestinal drug delivery system |
| EP1183014B1 (en) * | 1999-06-14 | 2003-10-08 | Cosmo S.p.A. | Controlled release and taste masking oral pharmaceutical compositions |
| US20010034340A1 (en) * | 2000-03-20 | 2001-10-25 | American Home Products Corporation | Hormone replacement therapy |
-
2002
- 2002-11-29 TW TW091134751A patent/TWI252111B/zh not_active IP Right Cessation
- 2002-12-09 AR ARP020104765A patent/AR037760A1/es not_active Application Discontinuation
- 2002-12-12 PT PT02796612T patent/PT1465602E/pt unknown
- 2002-12-12 AU AU2002361396A patent/AU2002361396B2/en not_active Ceased
- 2002-12-12 SI SI200230848T patent/SI1465602T1/sl unknown
- 2002-12-12 CA CA2470207A patent/CA2470207C/en not_active Expired - Fee Related
- 2002-12-12 EP EP02796612A patent/EP1465602B1/de not_active Expired - Lifetime
- 2002-12-12 PL PL369367A patent/PL205739B1/pl unknown
- 2002-12-12 CN CNB028262034A patent/CN100542538C/zh not_active Expired - Fee Related
- 2002-12-12 ES ES02796612T patent/ES2328910T3/es not_active Expired - Lifetime
- 2002-12-12 DE DE50213751T patent/DE50213751D1/de not_active Expired - Lifetime
- 2002-12-12 DK DK02796612T patent/DK1465602T3/da active
- 2002-12-12 BR BR0215044-1A patent/BR0215044A/pt active Search and Examination
- 2002-12-12 MX MXPA04005769A patent/MXPA04005769A/es active IP Right Grant
- 2002-12-12 WO PCT/EP2002/014103 patent/WO2003051336A1/de not_active Ceased
- 2002-12-12 JP JP2003552269A patent/JP4695837B2/ja not_active Expired - Fee Related
- 2002-12-12 AT AT02796612T patent/ATE438384T1/de active
-
2004
- 2004-06-14 US US10/866,094 patent/US8268351B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| TW200408414A (en) | 2004-06-01 |
| CN1607943A (zh) | 2005-04-20 |
| TWI252111B (en) | 2006-04-01 |
| CA2470207C (en) | 2012-07-10 |
| HK1075005A1 (zh) | 2005-12-02 |
| SI1465602T1 (sl) | 2009-12-31 |
| US8268351B2 (en) | 2012-09-18 |
| PL369367A1 (en) | 2005-04-18 |
| ES2328910T3 (es) | 2009-11-19 |
| ATE438384T1 (de) | 2009-08-15 |
| US20050019408A1 (en) | 2005-01-27 |
| WO2003051336A1 (de) | 2003-06-26 |
| AU2002361396B2 (en) | 2008-02-14 |
| DE50213751D1 (de) | 2009-09-17 |
| PT1465602E (pt) | 2009-09-07 |
| EP1465602A1 (de) | 2004-10-13 |
| JP4695837B2 (ja) | 2011-06-08 |
| BR0215044A (pt) | 2004-11-03 |
| MXPA04005769A (es) | 2004-09-10 |
| CA2470207A1 (en) | 2003-06-26 |
| PL205739B1 (pl) | 2010-05-31 |
| EP1465602B1 (de) | 2009-08-05 |
| AU2002361396A1 (en) | 2003-06-30 |
| JP2005513059A (ja) | 2005-05-12 |
| CN100542538C (zh) | 2009-09-23 |
| DK1465602T3 (da) | 2009-09-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal |