AR033631A1 - 1-oxa-3,9-diaza-espiro[5.5]undecan-2-onas - Google Patents

1-oxa-3,9-diaza-espiro[5.5]undecan-2-onas

Info

Publication number
AR033631A1
AR033631A1 ARP020101705A ARP020101705A AR033631A1 AR 033631 A1 AR033631 A1 AR 033631A1 AR P020101705 A ARP020101705 A AR P020101705A AR P020101705 A ARP020101705 A AR P020101705A AR 033631 A1 AR033631 A1 AR 033631A1
Authority
AR
Argentina
Prior art keywords
lower alkyl
compounds
espiro
onas
undecan
Prior art date
Application number
ARP020101705A
Other languages
English (en)
Spanish (es)
Inventor
Hai-Ying Cai
Michael Patrick Dillon
Guido Galley
Annick Goergler
Sabine Kolczewski
Dawn Marie Muszynski
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of AR033631A1 publication Critical patent/AR033631A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/10—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/537—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines spiro-condensed or forming part of bridged ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Psychiatry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
ARP020101705A 2001-05-14 2002-05-10 1-oxa-3,9-diaza-espiro[5.5]undecan-2-onas AR033631A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP01111644 2001-05-14

Publications (1)

Publication Number Publication Date
AR033631A1 true AR033631A1 (es) 2003-12-26

Family

ID=8177412

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP020101705A AR033631A1 (es) 2001-05-14 2002-05-10 1-oxa-3,9-diaza-espiro[5.5]undecan-2-onas

Country Status (17)

Country Link
US (1) US6599900B2 (OSRAM)
EP (1) EP1390372B1 (OSRAM)
JP (1) JP4056887B2 (OSRAM)
KR (1) KR100618063B1 (OSRAM)
CN (1) CN1264847C (OSRAM)
AR (1) AR033631A1 (OSRAM)
AT (1) ATE401333T1 (OSRAM)
AU (1) AU2002342238B2 (OSRAM)
BR (1) BR0209604A (OSRAM)
CA (1) CA2447329C (OSRAM)
DE (1) DE60227657D1 (OSRAM)
DK (1) DK1390372T3 (OSRAM)
ES (1) ES2310206T3 (OSRAM)
MX (1) MXPA03010321A (OSRAM)
PT (1) PT1390372E (OSRAM)
WO (1) WO2002092604A1 (OSRAM)
ZA (1) ZA200308535B (OSRAM)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2554671A1 (en) 2004-02-10 2005-08-18 F.Hoffmann-La Roche Ag Chemokine ccr5 receptor modulators
UA90708C2 (ru) 2005-02-25 2010-05-25 Ф. Хоффманн-Ля Рош Аг Таблетки с улучшенной дисперсностью лекарственного вещества
EA012421B1 (ru) * 2005-03-03 2009-10-30 Янссен Фармацевтика Н. В. Замещённые производные оксадиазаспиро[5.5]ундеканона и их применение в качестве антагонистов нейрокинина
CN101137657B (zh) 2005-03-08 2011-02-02 詹森药业有限公司 作为神经激肽（nk1）拮抗剂的二氮杂-螺-[4.4]-壬烷衍生物
US7470684B2 (en) * 2007-01-03 2008-12-30 Hoffmann-La Roche Inc. Spiropiperidine derivatives as NK3 antagonists
EP2117538A1 (en) 2007-01-24 2009-11-18 Glaxo Group Limited Pharmaceutical compositions comprising 2-methoxy-5- (5-trifluoromethyl-tetrazol-i-yl-benzyl) - (2s-phenyl-piperidin-3s-yl-)
BRPI0809646A2 (pt) 2007-03-29 2014-09-23 Hoffmann La Roche Compostod antivirais heterocíclicos
CN107849017B (zh) 2015-07-31 2021-03-30 辉瑞公司 作为magl抑制剂的1,1,1-三氟-3-羟基丙-2-基氨基甲酸酯衍生物及1,1,1-三氟-4-羟基丁-2-基氨基甲酸酯衍生物
AU2018208846A1 (en) 2017-01-20 2019-07-25 Pfizer Inc. 1,1,1-trifluoro-3-hydroxypropan-2-yl carbamate derivatives as magl inhibitors
WO2018134698A1 (en) 2017-01-23 2018-07-26 Pfizer Inc. Heterocyclic spiro compounds as magl inhibitors
WO2020048826A1 (en) 2018-09-03 2020-03-12 Bayer Aktiengesellschaft 5-substituted 1-oxa-3,9-diazaspiro[5.5]undecan-2-one compounds
WO2020048827A1 (en) 2018-09-03 2020-03-12 Bayer Aktiengesellschaft 1, 3, 9-triazaspiro[5.5] undecan-2-one compounds

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2131021B (en) * 1982-11-24 1985-12-18 Erba Farmitalia Antipsychotic benzoxazines
IL111960A (en) * 1993-12-17 1999-12-22 Merck & Co Inc Morpholines and thiomorpholines their preparation and pharmaceutical compositions containing them
DE69633245T2 (de) * 1995-09-29 2005-09-08 Eli Lilly And Co., Indianapolis Spiroverbindungen als Inhibitoren der Fibrinogen-abhängigen Blutplättchenaggregation

Also Published As

Publication number Publication date
PT1390372E (pt) 2008-08-25
CN1507449A (zh) 2004-06-23
CA2447329C (en) 2009-07-28
DE60227657D1 (de) 2008-08-28
CA2447329A1 (en) 2002-11-21
CN1264847C (zh) 2006-07-19
JP2004534758A (ja) 2004-11-18
EP1390372B1 (en) 2008-07-16
BR0209604A (pt) 2004-03-23
ES2310206T3 (es) 2009-01-01
US20030004163A1 (en) 2003-01-02
WO2002092604A1 (en) 2002-11-21
ATE401333T1 (de) 2008-08-15
US6599900B2 (en) 2003-07-29
KR20030094405A (ko) 2003-12-11
MXPA03010321A (es) 2004-02-17
DK1390372T3 (da) 2008-09-15
KR100618063B1 (ko) 2006-08-30
ZA200308535B (en) 2005-01-31
JP4056887B2 (ja) 2008-03-05
EP1390372A1 (en) 2004-02-25
AU2002342238B2 (en) 2007-01-25

Similar Documents

Publication Publication Date Title
AR033631A1 (es) 1-oxa-3,9-diaza-espiro[5.5]undecan-2-onas
DK0562956T3 (da) Hidtil ukendte naphthylalkylaminer, fremgangsmåde til fremstilling heraf og farmaceutiske midler, som indeholder dem
AR037489A1 (es) Quinolinas sustituidas y proceso para su preparacion
PE20010009A1 (es) Derivados de fenil - y piridinilo como antagonistas del receptor de la neuroquinina 1
AR030507A1 (es) Compuesto de pirazolopiridina y los usos farmaceuticos del mismo
NO902954D0 (no) Fremgangsmaate for fremstilling av substituerte kinazolinoner som angitensin ii-antagonister.
PA8592001A1 (es) Activadores de glocoquinasa heteroaromaticos de seis miembros 5-sustituidos
ES2184772T3 (es) Derivados de bifenilo, procedimiento para su preparacion y su utilizacion como medicamentos.
PA8491101A1 (es) Derivados de 4-fenil-piridin.
ECSP034932A (es) Derivados de tetrahidroquinolina
SE0104332D0 (sv) Therapeutic agents
ES2151192T3 (es) Compuestos de quinolina y quinazolina utiles en terapia.
CO5130004A1 (es) 1-aril-3-arilmetil-1,8-naftiridin-4(1h)-onas
DE69838662D1 (de) Morphinanderivate und ihre medizinische Anwendung
PA8575001A1 (es) Fluorobenzamidas como inhibidores de maob
ES2141787T3 (es) Derivados de la 1,2,3,4-tetrahidro-9-acridinamina.
NO20050664L (no) 2,4 substituerte indoler og anvendelse derav som 5-HT6 modulatorer
NO20050666L (no) 2,7-substituerte indoler og deres anvendelse som 5-HT6 modulatorer
AR037221A1 (es) Compuestos derivados de piridina, uso de los mismos, un procedimiento para su preparacion y un medicamento que contiene uno o mas de dichos compuestos
IL169257A0 (en) Cycloalkene dicarboxylic acid compounds as anti-infammatory, immunomodulatory and anti-proliferatory agents
UY27232A1 (es) Nuevos compuestos de dihidropirimidina ciano substituidos y su uso para tratar padecimientos
NO20000737L (no) Tetrahydro <gamma>-karboliner
AR041898A1 (es) Derivados de 4(fenil-piperazinil-metil) benzamida y sus usos para el tratamiento del dolor y desordenes gastrointestinales
PE25998A1 (es) DERIVADOS DE OCTAHIDRO-PIRROLO(1,2-a)-PIRAZINA 2,7-SUSTITUIDOS
YU86603A (sh) Novi derivati piperidinkarboksamida, postupak za njihovo pripremanje i farmaceutske kompozicije koje ih sadrže

Legal Events

Date Code Title Description
FB Suspension of granting procedure