AR030275A1 - Composicion que inhibe la apoptosis y uso de un compuesto 15-ceto-prostaglandina- para producirla - Google Patents
Composicion que inhibe la apoptosis y uso de un compuesto 15-ceto-prostaglandina- para producirlaInfo
- Publication number
- AR030275A1 AR030275A1 ARP010101368A ARP010101368A AR030275A1 AR 030275 A1 AR030275 A1 AR 030275A1 AR P010101368 A ARP010101368 A AR P010101368A AR P010101368 A ARP010101368 A AR P010101368A AR 030275 A1 AR030275 A1 AR 030275A1
- Authority
- AR
- Argentina
- Prior art keywords
- group
- heterocyclic
- oxo
- aryl
- hydroxyl
- Prior art date
Links
- 230000006907 apoptotic process Effects 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title abstract 2
- 239000002131 composite material Substances 0.000 title 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 4
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 125000003118 aryl group Chemical group 0.000 abstract 3
- 229910052736 halogen Inorganic materials 0.000 abstract 3
- 150000002367 halogens Chemical class 0.000 abstract 3
- 125000000623 heterocyclic group Chemical group 0.000 abstract 3
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 3
- 125000004043 oxo group Chemical group O=* 0.000 abstract 3
- 125000001931 aliphatic group Chemical group 0.000 abstract 2
- 125000004104 aryloxy group Chemical group 0.000 abstract 2
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 2
- 229920006395 saturated elastomer Polymers 0.000 abstract 2
- 125000004423 acyloxy group Chemical group 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 125000002768 hydroxyalkyl group Chemical group 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
- A61K31/5575—Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
- A61K31/558—Eicosanoids, e.g. leukotrienes or prostaglandins having heterocyclic rings containing oxygen as the only ring hetero atom, e.g. thromboxanes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Ophthalmology & Optometry (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Hospice & Palliative Care (AREA)
- Vascular Medicine (AREA)
- Psychiatry (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US19175500P | 2000-03-24 | 2000-03-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR030275A1 true AR030275A1 (es) | 2003-08-20 |
Family
ID=22706808
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP010101368A AR030275A1 (es) | 2000-03-24 | 2001-03-23 | Composicion que inhibe la apoptosis y uso de un compuesto 15-ceto-prostaglandina- para producirla |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US7129272B2 (https=) |
| EP (1) | EP1267882B1 (https=) |
| JP (1) | JP2003527430A (https=) |
| KR (1) | KR100788226B1 (https=) |
| CN (1) | CN1443070A (https=) |
| AR (1) | AR030275A1 (https=) |
| AT (1) | ATE428429T1 (https=) |
| AU (2) | AU3955101A (https=) |
| CA (1) | CA2403086C (https=) |
| DE (1) | DE60138371D1 (https=) |
| NZ (1) | NZ521464A (https=) |
| TW (1) | TWI284535B (https=) |
| WO (1) | WO2001070233A2 (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1420794B1 (en) | 2001-08-31 | 2017-12-27 | Sucampo AG | Prostaglandin analogs as chloride channel openers |
| CN1605336A (zh) | 2003-10-10 | 2005-04-13 | 中国医学科学院药物研究所 | 左旋丁基苯酞在制备预防和治疗脑梗塞的药物中的应用 |
| DK1841433T3 (da) * | 2005-01-27 | 2012-01-16 | Sucampo Ag | Præparat til behandling af lidelser i centralnervesystemet |
| KR101396731B1 (ko) * | 2005-03-31 | 2014-05-19 | 산텐 세이야꾸 가부시키가이샤 | 프로스타글란딘 Ｆ２ａ 유도체를 유효 성분으로서 함유하는망막신경세포 보호제 |
| CN101160128B (zh) | 2005-04-13 | 2010-08-18 | 宇部兴产株式会社 | 含有吲唑衍生物作为有效成分的视网膜神经细胞保护剂 |
| US20070037193A1 (en) * | 2005-08-12 | 2007-02-15 | Rong-Hwa Lin | Modulation of peroxisome proliferator-activated receptors |
| US8871752B2 (en) | 2008-02-19 | 2014-10-28 | Sucampo Ag | Method for modulating stem cell growth |
| WO2010027040A1 (ja) * | 2008-09-04 | 2010-03-11 | 参天製薬株式会社 | １５，１５－ジフルオロプロスタグランジンＦ2α誘導体を有効成分として含有する毛髪成長促進剤 |
| US9084815B2 (en) * | 2009-09-16 | 2015-07-21 | Sucampo Ag | Method for treating damage induced by an anti-tumor agent, treating mucositis and treating tumor |
| WO2014159679A1 (en) | 2013-03-12 | 2014-10-02 | The United States Of America, As Represented By The Secretary, Department Of Health & Human Services | Methods for using lubiprostone to absorb fluid from the subretinal space |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5166174A (en) | 1987-01-28 | 1992-11-24 | K.K. Ueno Seiyaku Oyo Kenkyujo | Prostaglandins E and anti-ulcers containing same |
| CA1322749C (en) | 1987-01-28 | 1993-10-05 | Ryuzo Ueno | Prostaglandins of the d series, and tranquilizers and soporifics containing the same |
| US5221763A (en) | 1987-04-30 | 1993-06-22 | R-Tech Ueno, Ltd. | Prostaglandins of the F series |
| ES2052735T3 (es) * | 1987-09-18 | 1994-07-16 | R Tech Ueno Ltd | Un metodo para producir un agente hipotensor ocular. |
| CA2030345C (en) * | 1989-11-22 | 1998-12-08 | Ryuji Ueno | Use of 15-keto-prostaglandin compound for improvement of encephalic function |
| JPH0761944B2 (ja) * | 1989-11-22 | 1995-07-05 | 株式会社アールテック・ウエノ | 脳機能改善処置剤 |
| TW224942B (https=) | 1990-04-04 | 1994-06-11 | Adka Ueno Kk | |
| CA2150287C (en) | 1994-06-03 | 2004-08-10 | Ryuji Ueno | Agent for treating hepato-biliary diseases |
| JP3625946B2 (ja) * | 1995-03-10 | 2005-03-02 | 株式会社アールテック・ウエノ | 視神経障害改善剤 |
| JPH08277222A (ja) * | 1995-04-05 | 1996-10-22 | Green Cross Corp:The | 神経疾患の予防治療剤 |
| US6087395A (en) | 1997-10-21 | 2000-07-11 | Japan Science And Technology Corporation | Isocarbacyclin derivatives as apoptosis inhibitors |
| JP3964060B2 (ja) * | 1997-10-21 | 2007-08-22 | 独立行政法人科学技術振興機構 | アポトーシス抑制剤 |
| JP2000169394A (ja) * | 1998-12-04 | 2000-06-20 | Yoshitomi Pharmaceut Ind Ltd | アポトーシス誘導剤 |
-
2001
- 2001-03-23 EP EP01914192A patent/EP1267882B1/en not_active Expired - Lifetime
- 2001-03-23 KR KR1020027012410A patent/KR100788226B1/ko not_active Expired - Fee Related
- 2001-03-23 NZ NZ521464A patent/NZ521464A/en not_active IP Right Cessation
- 2001-03-23 AR ARP010101368A patent/AR030275A1/es unknown
- 2001-03-23 JP JP2001568431A patent/JP2003527430A/ja active Pending
- 2001-03-23 CA CA2403086A patent/CA2403086C/en not_active Expired - Fee Related
- 2001-03-23 WO PCT/JP2001/002307 patent/WO2001070233A2/en not_active Ceased
- 2001-03-23 AU AU3955101A patent/AU3955101A/xx active Pending
- 2001-03-23 TW TW090107002A patent/TWI284535B/zh not_active IP Right Cessation
- 2001-03-23 AT AT01914192T patent/ATE428429T1/de not_active IP Right Cessation
- 2001-03-23 CN CN01809737A patent/CN1443070A/zh active Pending
- 2001-03-23 DE DE60138371T patent/DE60138371D1/de not_active Expired - Lifetime
- 2001-03-23 AU AU2001239551A patent/AU2001239551B8/en not_active Ceased
- 2001-03-26 US US09/816,655 patent/US7129272B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| WO2001070233A2 (en) | 2001-09-27 |
| TWI284535B (en) | 2007-08-01 |
| AU2001239551B8 (en) | 2005-11-24 |
| NZ521464A (en) | 2004-09-24 |
| JP2003527430A (ja) | 2003-09-16 |
| CA2403086C (en) | 2010-08-17 |
| ATE428429T1 (de) | 2009-05-15 |
| DE60138371D1 (de) | 2009-05-28 |
| CA2403086A1 (en) | 2001-09-27 |
| EP1267882B1 (en) | 2009-04-15 |
| WO2001070233A3 (en) | 2002-06-13 |
| KR20020081474A (ko) | 2002-10-26 |
| AU2001239551B2 (en) | 2005-07-21 |
| EP1267882A2 (en) | 2003-01-02 |
| US7129272B2 (en) | 2006-10-31 |
| CN1443070A (zh) | 2003-09-17 |
| US20020025985A1 (en) | 2002-02-28 |
| KR100788226B1 (ko) | 2007-12-26 |
| AU3955101A (en) | 2001-10-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |