AR030019A1 - Anticuerpos monoclonales humanos y fragmentos funcionales del mismo, un procedimiento para su produccion, composiciones farmaceuticas que los comprenden, una molecula aislada de acido nucleico, un plasmido recombinante, una celula hospedante y el uso de dichos anticuerpos para la manufactura de un m - Google Patents
Anticuerpos monoclonales humanos y fragmentos funcionales del mismo, un procedimiento para su produccion, composiciones farmaceuticas que los comprenden, una molecula aislada de acido nucleico, un plasmido recombinante, una celula hospedante y el uso de dichos anticuerpos para la manufactura de un mInfo
- Publication number
- AR030019A1 AR030019A1 ARP000102352A ARP000102352A AR030019A1 AR 030019 A1 AR030019 A1 AR 030019A1 AR P000102352 A ARP000102352 A AR P000102352A AR P000102352 A ARP000102352 A AR P000102352A AR 030019 A1 AR030019 A1 AR 030019A1
- Authority
- AR
- Argentina
- Prior art keywords
- monoclonal antibodies
- human monoclonal
- nucleic acid
- pharmaceutical compositions
- production
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 102000039446 nucleic acids Human genes 0.000 title abstract 2
- 108020004707 nucleic acids Proteins 0.000 title abstract 2
- 150000007523 nucleic acids Chemical class 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 239000012634 fragment Substances 0.000 title 1
- 210000003205 muscle Anatomy 0.000 title 1
- 241000725643 Respiratory syncytial virus Species 0.000 abstract 2
- 206010061603 Respiratory syncytial virus infection Diseases 0.000 abstract 1
- 239000000032 diagnostic agent Substances 0.000 abstract 1
- 229940039227 diagnostic agent Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 108020001507 fusion proteins Proteins 0.000 abstract 1
- 102000037865 fusion proteins Human genes 0.000 abstract 1
- 239000013612 plasmid Substances 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56983—Viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
- C07K16/1027—Paramyxoviridae, e.g. respiratory syncytial virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
- G01N2333/08—RNA viruses
- G01N2333/115—Paramyxoviridae, e.g. parainfluenza virus
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US13470299P | 1999-05-18 | 1999-05-18 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR030019A1 true AR030019A1 (es) | 2003-08-13 |
Family
ID=22464579
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP000102352A AR030019A1 (es) | 1999-05-18 | 2000-05-16 | Anticuerpos monoclonales humanos y fragmentos funcionales del mismo, un procedimiento para su produccion, composiciones farmaceuticas que los comprenden, una molecula aislada de acido nucleico, un plasmido recombinante, una celula hospedante y el uso de dichos anticuerpos para la manufactura de un m |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP1178829A4 (fr) |
JP (1) | JP2002543822A (fr) |
AR (1) | AR030019A1 (fr) |
AU (1) | AU5441000A (fr) |
CO (1) | CO5280147A1 (fr) |
WO (1) | WO2000069462A1 (fr) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8597911B2 (en) | 2003-06-11 | 2013-12-03 | Chugai Seiyaku Kabushiki Kaisha | Process for producing antibodies |
TW200530269A (en) | 2003-12-12 | 2005-09-16 | Chugai Pharmaceutical Co Ltd | Anti-Mpl antibodies |
WO2006106905A1 (fr) | 2005-03-31 | 2006-10-12 | Chugai Seiyaku Kabushiki Kaisha | Procede pour la production de polypeptide au moyen de la regulation d’un ensemble |
US9493569B2 (en) | 2005-03-31 | 2016-11-15 | Chugai Seiyaku Kabushiki Kaisha | Structural isomers of sc(Fv)2 |
AU2006256041B2 (en) | 2005-06-10 | 2012-03-29 | Chugai Seiyaku Kabushiki Kaisha | Stabilizer for protein preparation comprising meglumine and use thereof |
AU2006256030B2 (en) * | 2005-06-10 | 2012-06-21 | Chugai Seiyaku Kabushiki Kaisha | Pharmaceutical compositions containing sc(Fv)2 |
KR101360671B1 (ko) | 2005-06-10 | 2014-02-07 | 추가이 세이야쿠 가부시키가이샤 | sc(Fv)2를 함유하는 의약조성물 |
US9670269B2 (en) | 2006-03-31 | 2017-06-06 | Chugai Seiyaku Kabushiki Kaisha | Methods of modifying antibodies for purification of bispecific antibodies |
EP1997830A1 (fr) * | 2007-06-01 | 2008-12-03 | AIMM Therapeutics B.V. | Molécules à liaison spécifiques RSV et leur moyen de fabrication |
DK2285408T3 (en) | 2008-06-05 | 2019-02-04 | Ablynx Nv | AMINO ACID SEQUENCES AGAINST COATING PROTEINS IN A VIRUS AND POLYPEPTIDES INCLUDING THESE FOR TREATMENT OF VIRUSAL DISEASES |
SG176095A1 (en) | 2009-06-05 | 2011-12-29 | Ablynx Nv | Monovalent, bivalent and trivalent anti human respiratory syncytial virus (hrsv) nanobody constructs for the prevention and/or treatment of respiratory tract infections |
US8568726B2 (en) | 2009-10-06 | 2013-10-29 | Medimmune Limited | RSV specific binding molecule |
EP2507262A1 (fr) * | 2009-11-30 | 2012-10-10 | Ablynx N.V. | Séquences d'acides aminés améliorées dirigées contre le virus syncytial respiratoire humain (hrsv) et polypeptides comprenant celles-ci pour la prévention et/ou le traitement d'infections du tractus respiratoire |
TWI659968B (zh) * | 2013-03-14 | 2019-05-21 | 再生元醫藥公司 | 針對呼吸道融合病毒f蛋白質的人類抗體及其使用方法 |
KR102441231B1 (ko) | 2013-09-27 | 2022-09-06 | 추가이 세이야쿠 가부시키가이샤 | 폴리펩티드 이종 다량체의 제조방법 |
JO3555B1 (ar) | 2015-10-29 | 2020-07-05 | Merck Sharp & Dohme | جسم مضاد يبطل فعالية فيروس الالتهاب الرئوي البشري |
AU2016381992B2 (en) | 2015-12-28 | 2024-01-04 | Chugai Seiyaku Kabushiki Kaisha | Method for promoting efficiency of purification of Fc region-containing polypeptide |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5824307A (en) * | 1991-12-23 | 1998-10-20 | Medimmune, Inc. | Human-murine chimeric antibodies against respiratory syncytial virus |
JP3976333B2 (ja) * | 1992-09-16 | 2007-09-19 | ザ スクリップス リサーチ インスティチュート | 呼吸合胞体ウイルスに対するヒト中和性モノクローナル抗体 |
US6019980A (en) * | 1995-06-07 | 2000-02-01 | Connaught Laboratories Limited | Nucleic acid respiratory syncytial virus vaccines |
US5811524A (en) * | 1995-06-07 | 1998-09-22 | Idec Pharmaceuticals Corporation | Neutralizing high affinity human monoclonal antibodies specific to RSV F-protein and methods for their manufacture and therapeutic use thereof |
WO1998019704A1 (fr) * | 1996-11-01 | 1998-05-14 | Smithkline Beecham Corporation | Anticorps monoclonaux humains |
-
2000
- 2000-05-16 CO CO00035406A patent/CO5280147A1/es not_active Application Discontinuation
- 2000-05-16 AR ARP000102352A patent/AR030019A1/es not_active Application Discontinuation
- 2000-05-18 WO PCT/US2000/013694 patent/WO2000069462A1/fr not_active Application Discontinuation
- 2000-05-18 EP EP00939304A patent/EP1178829A4/fr not_active Withdrawn
- 2000-05-18 JP JP2000617922A patent/JP2002543822A/ja not_active Withdrawn
- 2000-05-18 AU AU54410/00A patent/AU5441000A/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
AU5441000A (en) | 2000-12-05 |
WO2000069462A1 (fr) | 2000-11-23 |
EP1178829A4 (fr) | 2005-06-08 |
JP2002543822A (ja) | 2002-12-24 |
CO5280147A1 (es) | 2003-05-30 |
EP1178829A1 (fr) | 2002-02-13 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
AR030019A1 (es) | Anticuerpos monoclonales humanos y fragmentos funcionales del mismo, un procedimiento para su produccion, composiciones farmaceuticas que los comprenden, una molecula aislada de acido nucleico, un plasmido recombinante, una celula hospedante y el uso de dichos anticuerpos para la manufactura de un m | |
ATE194291T1 (de) | Neutralisierende monoklonale antikörper gegen respiratorischen synzytialvirus | |
JP2002544238A5 (fr) | ||
CN105566497A (zh) | 融合铁蛋白在疫苗和其他方面的应用 | |
ATE267258T1 (de) | Impfstoffe für das respiratorische-synzytial- virus mit nuklein säuren | |
CA2181832A1 (fr) | Immunisation par inoculation d'une unite de transcription d'adn | |
WO2002072636A3 (fr) | Cristaux d'anticorps entiers et fragments d'anticorps et methodes de fabrication et d'utilisation associees | |
YU36302A (sh) | Novi tiotropiumski preparati - koji sadrže prah za inhaliranje | |
BR9907691A (pt) | Derivados de antìgeno associado a tumor da famìlia mage, e sequências de ácido nucléico codificando os mesmos, usados para a preparação de proteìnas de fusão e de composições para vacinação | |
JP2011521662A5 (fr) | ||
JP2004501618A5 (fr) | ||
JP2009520758A5 (fr) | ||
WO2001096587A8 (fr) | Procede d'administration de virions recombinants de virus associes aux adenovirus a des etres humains ayant ete exposes a ce type de virus | |
AR035867A1 (es) | Una particula semejante a un virus hcv formada por una proteina de envoltura de hcv, un metodo para formar dicha particula, un medicamento que la contiene, una vacuna, un metodo de deteccion, un kit de diagnostico, el uso de cepas de hansenula o saccharomyces para la expresion de una proteina hcv, e | |
CN111440229A (zh) | 新型冠状病毒t细胞表位及其应用 | |
Zhang et al. | Protective immunity induced by peptides of AMA1, RON2 and RON4 containing T-and B-cell epitopes via an intranasal route against toxoplasmosis in mice | |
CN105106945B (zh) | 一种幽门螺旋杆菌四价毒力因子多表位疫苗及其制备方法 | |
JPH02109994A (ja) | モノクローナル抗体及びそれから誘導されたフラグメントによるTNF‐αの試験管内及び生体内毒性の中和 | |
CN107849551A (zh) | 新型胰蛋白酶同功异型物和其用途 | |
HUP0401605A2 (hu) | Szembetegségek kezelésére szolgáló integrin gátlók | |
WO2003079993A3 (fr) | Preparations d'hormone de croissance humaine (hch) destinees a etre administrees par voie pulmonaire | |
CN111153988B (zh) | 广谱抗肠道病毒d68型的中和性单克隆抗体 | |
WO2004037175A3 (fr) | Compositions et methodes pour traiter une maladie a mediation par le papillomavirus humain (hpv) | |
CN116406274A (zh) | 用于治疗冠状病毒的cd3抗体 | |
Shi et al. | Expression, purification, and characterization of scar tissue neovasculature endothelial cell-targeted rhIL10 in Escherichia coli |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA | Abandonment or withdrawal |