AR028775A1 - Derivados de la pirimidina y su uso para la profilaxis y la terapia de isquemia cerebral - Google Patents

Derivados de la pirimidina y su uso para la profilaxis y la terapia de isquemia cerebral

Info

Publication number
AR028775A1
AR028775A1 ARP010103153A ARP010103153A AR028775A1 AR 028775 A1 AR028775 A1 AR 028775A1 AR P010103153 A ARP010103153 A AR P010103153A AR P010103153 A ARP010103153 A AR P010103153A AR 028775 A1 AR028775 A1 AR 028775A1
Authority
AR
Argentina
Prior art keywords
therapy
cerebral ischemia
profilaxis
pyrimidine
derivatives
Prior art date
Application number
ARP010103153A
Other languages
English (en)
Original Assignee
Knoll Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Knoll Ag filed Critical Knoll Ag
Publication of AR028775A1 publication Critical patent/AR028775A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D495/14—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

Un derivado 3-sustituido de 5,6,7,8-tetrahidropirido [4,3:4,5]tieno[2,3-d]pirimidin-4(3H)-ona de la formula (1), donde R1 es hidrogeno o alquilo C1-4, y las sales fisiologicamente toleradas de ellos. Uso de los compuestos de formula (1) para producir drogas para la profilaxis y la terapia de la neurodegeneracion, el trauma cerebral y la isquemia cerebral, en particular el ataque apoplético, y de las secuelas ocasionadas por estas enfermedades.
ARP010103153A 2000-07-03 2001-07-02 Derivados de la pirimidina y su uso para la profilaxis y la terapia de isquemia cerebral AR028775A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10031389A DE10031389A1 (de) 2000-07-03 2000-07-03 Pyrimidinderivate und ihre Verwendung zur Prophylaxe und Therapie der zerebralen Ischämie

Publications (1)

Publication Number Publication Date
AR028775A1 true AR028775A1 (es) 2003-05-21

Family

ID=7647038

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP010103153A AR028775A1 (es) 2000-07-03 2001-07-02 Derivados de la pirimidina y su uso para la profilaxis y la terapia de isquemia cerebral

Country Status (4)

Country Link
AR (1) AR028775A1 (es)
AU (1) AU2001287578A1 (es)
DE (1) DE10031389A1 (es)
WO (1) WO2002002569A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1497415B1 (en) * 2002-04-19 2010-12-29 ZymoGenetics, L.L.C. Methods for detection or modulation of the interaction of a cytokine receptor with its ligand

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19636769A1 (de) * 1996-09-10 1998-03-12 Basf Ag 3-Substituierte Pyrido [4',3':4,5]thieno[2,3-d]pyrimidin-Derivate, ihre Herstellung und Verwendung
DE19724980A1 (de) * 1997-06-13 1998-12-17 Basf Ag 3-Substituierte 3,4-Dihydro-thieno[2,3-d]pyrimidin-Derivate, ihre Herstellung und Verwendung
DE19724979A1 (de) * 1997-06-13 1998-12-17 Basf Ag 3-substituierte Pyrido [3,4,5]thieno[2,3-d]pyrimidin-Derivate, ihre Herstellung und Verwendung
US5960613A (en) * 1997-08-28 1999-10-05 Murray, Inc. Ride-on mower having bag-full indicator
DE19900545A1 (de) * 1999-01-11 2000-07-13 Basf Ag Verwendung von Pyrimidinderivaten zur Prophylaxe und Therapie der zerebralen Ischämie
DE19900673A1 (de) * 1999-01-11 2000-07-13 Basf Ag Verwendung von Bindungspartnern für 5-HT5-Rezeptoren zur Behandlung neurodegenerativer und neuropsychiatrischer Störungen

Also Published As

Publication number Publication date
AU2001287578A1 (en) 2002-01-14
WO2002002569A1 (de) 2002-01-10
DE10031389A1 (de) 2002-01-17

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