AR027578A1 - Derivados de indano - Google Patents
Derivados de indanoInfo
- Publication number
- AR027578A1 AR027578A1 ARP010100942A ARP010100942A AR027578A1 AR 027578 A1 AR027578 A1 AR 027578A1 AR P010100942 A ARP010100942 A AR P010100942A AR P010100942 A ARP010100942 A AR P010100942A AR 027578 A1 AR027578 A1 AR 027578A1
- Authority
- AR
- Argentina
- Prior art keywords
- compounds
- prodrugs
- heteroaryl
- oxides
- indano
- Prior art date
Links
- 240000001546 Byrsonima crassifolia Species 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 150000001204 N-oxides Chemical class 0.000 abstract 2
- 125000003118 aryl group Chemical group 0.000 abstract 2
- 125000001072 heteroaryl group Chemical group 0.000 abstract 2
- 229940002612 prodrug Drugs 0.000 abstract 2
- 239000000651 prodrug Substances 0.000 abstract 2
- 229920006395 saturated elastomer Polymers 0.000 abstract 2
- 108010008212 Integrin alpha4beta1 Proteins 0.000 abstract 1
- 108010000134 Vascular Cell Adhesion Molecule-1 Proteins 0.000 abstract 1
- 102100023543 Vascular cell adhesion protein 1 Human genes 0.000 abstract 1
- 239000002253 acid Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 125000005842 heteroatom Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 230000003993 interaction Effects 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
- C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
- C07D263/58—Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/30—Nitrogen atoms not forming part of a nitro radical
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0004686.2A GB0004686D0 (en) | 2000-02-28 | 2000-02-28 | Chemical compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR027578A1 true AR027578A1 (es) | 2003-04-02 |
Family
ID=9886551
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP010100942A AR027578A1 (es) | 2000-02-28 | 2001-02-28 | Derivados de indano |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US6762199B2 (https=) |
| EP (1) | EP1259495B1 (https=) |
| JP (1) | JP5021133B2 (https=) |
| AR (1) | AR027578A1 (https=) |
| AT (1) | ATE277023T1 (https=) |
| AU (1) | AU3579001A (https=) |
| CA (1) | CA2401441C (https=) |
| DE (1) | DE60105771T2 (https=) |
| ES (1) | ES2227137T3 (https=) |
| GB (1) | GB0004686D0 (https=) |
| IL (1) | IL150724A0 (https=) |
| MX (1) | MXPA02008375A (https=) |
| WO (1) | WO2001064659A2 (https=) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4212358B2 (ja) | 2000-12-28 | 2009-01-21 | 第一三共株式会社 | Vla−4阻害薬 |
| GB0123765D0 (en) * | 2001-10-03 | 2001-11-21 | Bayer Ag | Para-amino benzoic acids |
| US8005919B2 (en) | 2002-11-18 | 2011-08-23 | Aol Inc. | Host-based intelligent results related to a character stream |
| CA2506585A1 (en) | 2002-11-18 | 2004-06-03 | Valerie Kucharewski | People lists |
| CA2528586A1 (en) | 2003-07-24 | 2005-02-03 | Daiichi Pharmaceutical Co., Ltd. | Cyclohexanecarboxylic acid compound |
| JP2006056830A (ja) * | 2004-08-20 | 2006-03-02 | Dai Ichi Seiyaku Co Ltd | 2−アリールアミノベンゾオキサゾール誘導体 |
| WO2012074980A2 (en) * | 2010-12-01 | 2012-06-07 | Dara Biosciences, Inc. | Methods of treating or preventing autoimmune disorders and liver disorders using indane acetic acid derivatives |
| US12522583B2 (en) | 2018-11-07 | 2026-01-13 | Dana-Farber Cancer Institute, Inc. | Benzimidazole derivatives and aza-benzimidazole derivatives as Janus kinase 2 inhibitors and uses thereof |
| EP3877371A4 (en) | 2018-11-07 | 2022-07-27 | Dana-Farber Cancer Institute, Inc. | IMIDAZOPYRIDINE DERIVATIVES AND AZA-IMIDAZOPYRIDINE DERIVATIVES AS JANUS KINASE 2 INHIBITORS AND USES THEREOF |
| EP3876939A4 (en) | 2018-11-07 | 2022-08-10 | Dana-Farber Cancer Institute, Inc. | Benzothiazole derivatives and 7-aza-benzothiazole derivatives as janus kinase 2 inhibitors and uses thereof |
| US11691963B2 (en) | 2020-05-06 | 2023-07-04 | Ajax Therapeutics, Inc. | 6-heteroaryloxy benzimidazoles and azabenzimidazoles as JAK2 inhibitors |
| US12043632B2 (en) | 2020-12-23 | 2024-07-23 | Ajax Therapeutics, Inc. | 6-heteroaryloxy benzimidazoles and azabenzimidazoles as JAK2 inhibitors |
| US12162881B2 (en) | 2021-11-09 | 2024-12-10 | Ajax Therapeutics, Inc. | Forms and compositions of inhibitors of JAK2 |
| WO2023086319A1 (en) | 2021-11-09 | 2023-05-19 | Ajax Therapeutics, Inc. | 6-he tero aryloxy benzimidazoles and azabenzimidazoles as jak2 inhibitors |
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| GB9916374D0 (en) * | 1998-07-23 | 1999-09-15 | Zeneca Ltd | Chemical compounds |
| JP2002521375A (ja) * | 1998-07-23 | 2002-07-16 | アストラゼネカ アクチエボラーク | 化合物 |
| WO2000049005A1 (en) * | 1999-02-16 | 2000-08-24 | Aventis Pharma Limited | Bicyclic compounds and their use as integrin receptor ligands |
| ES2321055T3 (es) * | 1999-05-05 | 2009-06-02 | Aventis Pharma Limited | Compuestos biblicos sustituidos. |
-
2000
- 2000-02-28 GB GBGB0004686.2A patent/GB0004686D0/en not_active Ceased
-
2001
- 2001-02-28 AR ARP010100942A patent/AR027578A1/es unknown
- 2001-02-28 DE DE60105771T patent/DE60105771T2/de not_active Expired - Lifetime
- 2001-02-28 ES ES01907923T patent/ES2227137T3/es not_active Expired - Lifetime
- 2001-02-28 JP JP2001563500A patent/JP5021133B2/ja not_active Expired - Lifetime
- 2001-02-28 EP EP01907923A patent/EP1259495B1/en not_active Expired - Lifetime
- 2001-02-28 CA CA2401441A patent/CA2401441C/en not_active Expired - Lifetime
- 2001-02-28 AT AT01907923T patent/ATE277023T1/de not_active IP Right Cessation
- 2001-02-28 WO PCT/GB2001/000844 patent/WO2001064659A2/en not_active Ceased
- 2001-02-28 MX MXPA02008375A patent/MXPA02008375A/es active IP Right Grant
- 2001-02-28 IL IL15072401A patent/IL150724A0/xx unknown
- 2001-02-28 AU AU35790/01A patent/AU3579001A/en not_active Abandoned
-
2002
- 2002-08-28 US US10/229,592 patent/US6762199B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| MXPA02008375A (es) | 2002-12-13 |
| JP5021133B2 (ja) | 2012-09-05 |
| WO2001064659A3 (en) | 2001-12-27 |
| GB0004686D0 (en) | 2000-04-19 |
| CA2401441C (en) | 2011-11-15 |
| EP1259495A2 (en) | 2002-11-27 |
| WO2001064659A2 (en) | 2001-09-07 |
| DE60105771T2 (de) | 2006-02-16 |
| CA2401441A1 (en) | 2001-09-07 |
| JP2003525281A (ja) | 2003-08-26 |
| IL150724A0 (en) | 2003-02-12 |
| EP1259495B1 (en) | 2004-09-22 |
| ES2227137T3 (es) | 2005-04-01 |
| US20030199564A1 (en) | 2003-10-23 |
| DE60105771D1 (de) | 2004-10-28 |
| US6762199B2 (en) | 2004-07-13 |
| ATE277023T1 (de) | 2004-10-15 |
| AU3579001A (en) | 2001-09-12 |
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