AR016229A1 - Genes utiles para incrementar el contenido proteico de plantas, proteinas codificadas por dichos genes, celulas de plantas transfectadas con dichos genesy metodos para incrementar el contenido proteico o no proteico de plantas - Google Patents
Genes utiles para incrementar el contenido proteico de plantas, proteinas codificadas por dichos genes, celulas de plantas transfectadas con dichos genesy metodos para incrementar el contenido proteico o no proteico de plantasInfo
- Publication number
- AR016229A1 AR016229A1 ARP990101938A ARP990101938A AR016229A1 AR 016229 A1 AR016229 A1 AR 016229A1 AR P990101938 A ARP990101938 A AR P990101938A AR P990101938 A ARP990101938 A AR P990101938A AR 016229 A1 AR016229 A1 AR 016229A1
- Authority
- AR
- Argentina
- Prior art keywords
- protein
- equal
- plants
- gene
- genes
- Prior art date
Links
- 108090000623 proteins and genes Proteins 0.000 title abstract 26
- 102000004169 proteins and genes Human genes 0.000 title abstract 16
- 238000000034 method Methods 0.000 title abstract 2
- 125000000539 amino acid group Chemical group 0.000 abstract 4
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 abstract 4
- 102000004877 Insulin Human genes 0.000 abstract 2
- 108090001061 Insulin Proteins 0.000 abstract 2
- 230000002209 hydrophobic effect Effects 0.000 abstract 2
- 229940125396 insulin Drugs 0.000 abstract 2
- 238000004519 manufacturing process Methods 0.000 abstract 2
- 235000016709 nutrition Nutrition 0.000 abstract 2
- 244000038559 crop plants Species 0.000 abstract 1
- 235000020776 essential amino acid Nutrition 0.000 abstract 1
- 239000003797 essential amino acid Substances 0.000 abstract 1
- 230000031787 nutrient reservoir activity Effects 0.000 abstract 1
- 230000035764 nutrition Effects 0.000 abstract 1
- 230000009261 transgenic effect Effects 0.000 abstract 1
- 230000014616 translation Effects 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
- C12N15/8251—Amino acid content, e.g. synthetic storage proteins, altering amino acid biosynthesis
- C12N15/8253—Methionine or cysteine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
- C12N15/8251—Amino acid content, e.g. synthetic storage proteins, altering amino acid biosynthesis
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
- C12N15/8251—Amino acid content, e.g. synthetic storage proteins, altering amino acid biosynthesis
- C12N15/8254—Tryptophan or lysine
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
- Y02A40/10—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in agriculture
- Y02A40/146—Genetically Modified [GMO] plants, e.g. transgenic plants
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Plant Pathology (AREA)
- Nutrition Science (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
Un gen que codifica una proteína seleccionada del grupo que consiste en )i) una proteína que comprende una secuencia alfa-helicoidal anfifílica donde dichasecuencia comprende (H)u((h)x(H)y)z(h)w donde H es un residuo de aminoácido hidrofílico y puedevariar a lo largo de dicha proteína, h es un residuo deaminoácido hidrofobico y puede variar a lo largo de dicha proteína, u es igual a 0 o 1, x es igual a 1 o 2, y es igual a 1 o 2, z está seleccionado del grupoque consiste en 5,6,7,8,9,10,11,12,13,14,15,16, 17, 18, 19, 20, y cualquier numero entero superior a 20, y w es igual a 0,1 o 2, y donde el valor de x en un((h)x(H)y) no necesita ser igual al valor de x en otro ((h)x(H)y) y donde el valor de y en un ((h)x(H)y) no necesita ser igual al valor de y en otro ((h)x(H)y)y (ii) una proteína que comprende una secuencia de una lámina beta-plegada donde dicha secuencia comprende (H)r(hH)s(h)t donde H es un residuo de aminoácidohidrofílico y puede variar a lo largo de dicha proteína, h es un residuo de aminoácido hidrofobico y puede variar a lo largo de dicha proteína r, es igual a 0o 1, s es cualquier numero entero superior a 0 y t es igual a 0,1 o 2. La proteína codificada es una proteína disenada de novo, de almacenamiento artificial hasido expresada establemente en plantas.Esta proteína fue disenada para poseer elevados niveles de todos los aminoácidos esenciales necesarios para la nutricionhumana. La expresion del gen que codifica para esta proteína en plantas de cultivo mejorará enormemente la calidad nutricional de los cultivos resultantes. Seha observado también que el gen aumenta el nivel general de produccion de proteínas en una planta. Esta propiedad permite mejorar los niveles de produccion deotras proteínas valiosasen una planta. Por ejemplo, una planta transgénica con un gen que codifica para la insulina puede producir niveles más elevados deinsulina cuando la planta expresa también un gen para una proteína de almacenamiento artificial. El método permite también mejorar la produccion de losproductos no proteicos. La co-transformacion con un gen de interés puede dar como resultado niveles incrementados del producto proteico del gen, de interés o
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US6605698A | 1998-04-27 | 1998-04-27 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR016229A1 true AR016229A1 (es) | 2001-06-20 |
Family
ID=22066979
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP990101938A AR016229A1 (es) | 1998-04-27 | 1999-04-27 | Genes utiles para incrementar el contenido proteico de plantas, proteinas codificadas por dichos genes, celulas de plantas transfectadas con dichos genesy metodos para incrementar el contenido proteico o no proteico de plantas |
Country Status (4)
Country | Link |
---|---|
AR (1) | AR016229A1 (es) |
AU (1) | AU3868199A (es) |
CA (1) | CA2325463A1 (es) |
WO (1) | WO1999055890A1 (es) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MXPA05013723A (es) * | 2003-06-17 | 2006-03-13 | Sembiosys Genetics Inc | Metodos para loa produccion de insulina en plantas. |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0675960A1 (en) * | 1987-11-02 | 1995-10-11 | Louisiana State University and Agricultural and Mechanical College | Plants genetically enhanced for disease resistance |
WO1993003160A1 (en) * | 1991-08-09 | 1993-02-18 | E.I. Du Pont De Nemours And Company | Synthetic storage proteins with defined structure containing programmable levels of essential amino acids for improvement of the nutritional value of plants |
FR2744134B1 (fr) * | 1996-01-29 | 1998-04-03 | Biocem | Proteines de reserve de plantes enrichies en acides amines, notamment alpha-zeine de mais enrichie en lysine plantes exprimant ces proteines |
-
1999
- 1999-04-27 WO PCT/US1999/009067 patent/WO1999055890A1/en active Application Filing
- 1999-04-27 AR ARP990101938A patent/AR016229A1/es unknown
- 1999-04-27 AU AU38681/99A patent/AU3868199A/en not_active Abandoned
- 1999-04-27 CA CA002325463A patent/CA2325463A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
AU3868199A (en) | 1999-11-16 |
CA2325463A1 (en) | 1999-11-04 |
WO1999055890A1 (en) | 1999-11-04 |
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