DE68927437D1 - Verfahren zur herstellung von luciferase durch rekombinante expression eines luciferase-kodierenden gens - Google Patents

Verfahren zur herstellung von luciferase durch rekombinante expression eines luciferase-kodierenden gens

Info

Publication number
DE68927437D1
DE68927437D1 DE68927437T DE68927437T DE68927437D1 DE 68927437 D1 DE68927437 D1 DE 68927437D1 DE 68927437 T DE68927437 T DE 68927437T DE 68927437 T DE68927437 T DE 68927437T DE 68927437 D1 DE68927437 D1 DE 68927437D1
Authority
DE
Germany
Prior art keywords
luciferase
recombinant expression
encoding gene
producing
dna sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE68927437T
Other languages
English (en)
Other versions
DE68927437T2 (de
Inventor
Jun Kazami
Haruji Nakamura
Toshio Goto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Toray Industries Inc
Original Assignee
Toray Industries Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toray Industries Inc filed Critical Toray Industries Inc
Application granted granted Critical
Publication of DE68927437D1 publication Critical patent/DE68927437D1/de
Publication of DE68927437T2 publication Critical patent/DE68927437T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0069Oxidoreductases (1.) acting on single donors with incorporation of molecular oxygen, i.e. oxygenases (1.13)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6897Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids involving reporter genes operably linked to promoters
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y113/00Oxidoreductases acting on single donors with incorporation of molecular oxygen (oxygenases) (1.13)
    • C12Y113/12Oxidoreductases acting on single donors with incorporation of molecular oxygen (oxygenases) (1.13) with incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases)(1.13.12)
    • C12Y113/12006Cypridina-luciferin 2-monooxygenase (1.13.12.6), i.e. cypridina-luciferase

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE68927437T 1988-08-09 1989-08-09 Verfahren zur herstellung von luciferase durch rekombinante expression eines luciferase-kodierenden gens Expired - Fee Related DE68927437T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP19929588 1988-08-09
JP20417388 1988-08-17
PCT/JP1989/000811 WO1990001542A1 (en) 1988-08-09 1989-08-09 Luciferase, luciferase-coding gene, and process for preparing luciferase

Publications (2)

Publication Number Publication Date
DE68927437D1 true DE68927437D1 (de) 1996-12-12
DE68927437T2 DE68927437T2 (de) 1997-03-06

Family

ID=26511452

Family Applications (1)

Application Number Title Priority Date Filing Date
DE68927437T Expired - Fee Related DE68927437T2 (de) 1988-08-09 1989-08-09 Verfahren zur herstellung von luciferase durch rekombinante expression eines luciferase-kodierenden gens

Country Status (5)

Country Link
EP (1) EP0387355B1 (de)
KR (1) KR900702010A (de)
AT (1) ATE145004T1 (de)
DE (1) DE68927437T2 (de)
WO (1) WO1990001542A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6247995B1 (en) 1996-02-06 2001-06-19 Bruce Bryan Bioluminescent novelty items
US5876995A (en) 1996-02-06 1999-03-02 Bryan; Bruce Bioluminescent novelty items
US6416960B1 (en) 1996-08-08 2002-07-09 Prolume, Ltd. Detection and visualization of neoplastic tissues and other tissues
US6458547B1 (en) 1996-12-12 2002-10-01 Prolume, Ltd. Apparatus and method for detecting and identifying infectious agents
AU765703B2 (en) 1998-03-27 2003-09-25 Bruce J. Bryan Luciferases, fluorescent proteins, nucleic acids encoding the luciferases and fluorescent proteins and the use thereof in diagnostics, high throughput screening and novelty items
EP1925320A3 (de) 1998-03-27 2008-09-03 Prolume, Ltd. Luciferasen, fluoreszierende Proteine, Nukleinsäuren zur Kodierung der Luciferasen und der fluoreszierenden Proteine sowie deren Verwendung zur Diagnose, zum Screening mit hohem Durchsatz und zur Behandlung neuartiger Probleme
US7879540B1 (en) 2000-08-24 2011-02-01 Promega Corporation Synthetic nucleic acid molecule compositions and methods of preparation
US7728118B2 (en) 2004-09-17 2010-06-01 Promega Corporation Synthetic nucleic acid molecule compositions and methods of preparation
US7989621B2 (en) 2005-09-26 2011-08-02 National Institute Of Advanced Industrial Science And Technology Method for producing substituted imidazo[1,2-A]pyrazines of (s)-1-(3-(2-sec-butyl-6-(1h-indol-3-yl)-3-oxo-3,7-dihydroimadazo[1,2-a]pyrazin-8-yl)propyl)guanidine

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU7751687A (en) * 1986-07-22 1988-02-10 Boyce Thompson Institute For Plant Research Inc. Use of bacterial luciferase structural genes for cloning and monitoring gene expression in microorganisms and for tagging and identification of genetically engineered organisms
JPH088863B2 (ja) * 1987-11-30 1996-01-31 キッコーマン株式会社 ルシフェラーゼ

Also Published As

Publication number Publication date
DE68927437T2 (de) 1997-03-06
EP0387355A1 (de) 1990-09-19
EP0387355A4 (en) 1991-01-23
EP0387355B1 (de) 1996-11-06
WO1990001542A1 (en) 1990-02-22
KR900702010A (ko) 1990-12-05
ATE145004T1 (de) 1996-11-15

Similar Documents

Publication Publication Date Title
IE811463L (en) Interferons
KR880014110A (ko) 인체 프로아포지방단백질 a-i의 발현
ATE91716T1 (de) Verfahren zur herstellung vielkettige polypeptide oder proteine.
DE59610898D1 (de) Verfahren zur herstellung von erythropoietin frei von tierischen proteinen
ATE282093T1 (de) Verfahren zur herstellung von proteinprodukten in aspergillus-oryzae und in aspergillus zu verwendender promotor
ATE121781T1 (de) Verwendung von dns-fragmenten, die ein signalpeptid kodieren zur sekretion von reifen proteinen in rekombinanten hefen, expressions- kassetten, transformierte hefen und verfahren zur herstellung dieser proteine.
DE68927437D1 (de) Verfahren zur herstellung von luciferase durch rekombinante expression eines luciferase-kodierenden gens
DE69738079D1 (de) Systeme zur massenherstellung von proteinen oder peptiden durch mikroorganismen der gattung humicola
DE69013811D1 (de) Verfahren zur Herstellung von antiviralem Protein unter Benützung von E.coli-Transformant, das Gen, das für dieses Protein kodiert und E.coli-Vektor benützt in diesem Verfahren.
DE3785798D1 (de) Verfahren zur gentechnologischengewinnung von proteinen unter verwendung gramnegativer wirtzellen.
DE59410401D1 (de) VERFAHREN ZUR HERSTELLUNG REKOMBINANTER PilC-PROTEINE
DE139216T1 (de) Adult t-zell-leukemiavirus-antigenpeptid.
ATE162852T1 (de) Biosynthetisches verfahren zur herstellung von protein
ATE45184T1 (de) Vektor, teilweise oder voellig modifiziert mit dem lam b gen und mit diesem vektor modifizierte mikroorganismen befaehigt zum synthetisieren eines bestimmten externmembran-proteins, kodiert durch ein inserat ebenfalls enthalten im genannten vektor.
DE68920321D1 (de) Verfahren zur herstellung eines menschlichen "neutrophil chemotactic factor"-polypeptids.
EE03074B1 (et) Rekombinantsed eukarüootsed rakud, nende saamiseks vajalikud DNA järjestused, meetod eukarüootsete rakkude konstrueerimiseks ja sekreteeritavate valkude ning biomassi tootmismeetod
DE3882455D1 (de) Verfahren zur herstellung von proteinen in loeslicher form.
EP0422217A4 (en) Human recombinant placental ribonuclease inhibitor and method of production
EP0171000A3 (de) Verfahren zur Herstellung eines heterologen, reifen Proteins oder Peptids
RU96121465A (ru) Биосинтез рибофлавина в грибах
DK82391D0 (da) Ekspression og bearbejdning i gaer af autentiske humane fibroblastvaekstfaktorer
ATE191007T1 (de) Verfahren zur rekombinanten herstellung von proteinen in der hefe hansenula
DE69922071D1 (de) Tumor-suppressorgen Del-27 und das dadurch kodierte Protein, verfahren zu deren Herstellung und Nutzung
EP0165759A3 (de) Säugetierpromotoren verwendbar in Hefeexpression
HUT47633A (en) Process for producing artificial gene and protein product

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee