AR012601A1 - Derivados de amidina, formulaciones farmaceuticas que los contiene, uso de dichos derivados en la preparacion de medicamentos y proceso para lapreparacion de dichos derivados - Google Patents

Derivados de amidina, formulaciones farmaceuticas que los contiene, uso de dichos derivados en la preparacion de medicamentos y proceso para lapreparacion de dichos derivados

Info

Publication number
AR012601A1
AR012601A1 ARP980101928A ARP980101928A AR012601A1 AR 012601 A1 AR012601 A1 AR 012601A1 AR P980101928 A ARP980101928 A AR P980101928A AR P980101928 A ARP980101928 A AR P980101928A AR 012601 A1 AR012601 A1 AR 012601A1
Authority
AR
Argentina
Prior art keywords
derivatives
preparation
amidine
medicines
pharmaceutical formulations
Prior art date
Application number
ARP980101928A
Other languages
English (en)
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of AR012601A1 publication Critical patent/AR012601A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychology (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Derivados de amidina de formula (I), en la cual R1 representa un anillo de 2-tienilo o 3-tienilo y R2 representa hidrogeno o alquilo C 1 a 4 y susisomeros opticos y racematos y sus sales farmacéuticamente aceptables; procesos para su preparacion, composiciones que los contienen y su uso para prepararmedicamentos utiles en la inhibicion selectiva de la isoforma neuronal de la sintasa de oxido nítrico.
ARP980101928A 1997-05-05 1998-04-24 Derivados de amidina, formulaciones farmaceuticas que los contiene, uso de dichos derivados en la preparacion de medicamentos y proceso para lapreparacion de dichos derivados AR012601A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9701681A SE9701681D0 (sv) 1997-05-05 1997-05-05 New compounds

Publications (1)

Publication Number Publication Date
AR012601A1 true AR012601A1 (es) 2000-11-08

Family

ID=20406835

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP980101928A AR012601A1 (es) 1997-05-05 1998-04-24 Derivados de amidina, formulaciones farmaceuticas que los contiene, uso de dichos derivados en la preparacion de medicamentos y proceso para lapreparacion de dichos derivados

Country Status (25)

Country Link
US (1) US6489322B1 (es)
EP (1) EP0983268B1 (es)
JP (1) JP2001523262A (es)
KR (1) KR20010012228A (es)
CN (1) CN1255131A (es)
AR (1) AR012601A1 (es)
AT (1) ATE221065T1 (es)
AU (1) AU734391B2 (es)
BR (1) BR9809218A (es)
CA (1) CA2288333A1 (es)
DE (1) DE69806750T2 (es)
EE (1) EE9900474A (es)
HU (1) HUP0001873A3 (es)
ID (1) ID22885A (es)
IL (1) IL132678A0 (es)
IS (1) IS5236A (es)
MX (1) MXPA99009882A (es)
NO (1) NO995403L (es)
NZ (1) NZ500675A (es)
PL (1) PL336853A1 (es)
SE (1) SE9701681D0 (es)
SK (1) SK140599A3 (es)
TR (1) TR199902720T2 (es)
WO (1) WO1998050382A1 (es)
ZA (1) ZA983736B (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI243164B (en) * 2001-02-13 2005-11-11 Aventis Pharma Gmbh Acylated indanyl amines and their use as pharmaceuticals
US20030045449A1 (en) * 2001-08-15 2003-03-06 Pfizer, Inc. Pharmaceutical combinations for the treatment of neurodegenerative diseases
WO2006118104A1 (ja) * 2005-04-26 2006-11-09 Kabushiki Kaisha Toshiba 白色ｌｅｄおよびそれを用いたバックライト並びに液晶表示装置
US20100105657A1 (en) * 2005-07-05 2010-04-29 Astrazeneca Ab Compounds, Process for their Preparation, Intermediates, Pharmaceutical Compositions and their use in the Treatment of 5-HT6 Mediated Disorders such as Alzheimer's Disease, Cognitive Disorders, Cognitive Impairment Associated with Schizophrenia, Obesity and Parkinson's Disease
MY148644A (en) 2005-07-18 2013-05-15 Orion Corp New pharmaceutical compounds
EP2077846B1 (en) * 2006-11-02 2011-10-12 Piramal Life Sciences Limited Benzoxazepine compounds, their preparation and use
JP5497429B2 (ja) 2007-03-07 2014-05-21 武田薬品工業株式会社 ベンゾオキサゼピン誘導体およびその用途
WO2008144483A2 (en) * 2007-05-18 2008-11-27 Armgo Pharma, Inc. Agents for treating disorders involving modulation of ryanodine receptors
AU2010249790A1 (en) * 2009-05-22 2011-12-08 Exelixis, Inc. Benzoxazepines based P13K/mT0R inhibitors against proliferative diseases

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995005363A1 (en) 1993-08-12 1995-02-23 Astra Aktiebolag Amidine derivatives with nitric oxide synthetase activities
EP0723438A1 (en) 1993-10-04 1996-07-31 The Wellcome Foundation Limited Substituted urea and isothiourea derivatives as no synthase inhibitors
JPH09504028A (ja) 1993-10-21 1997-04-22 ジー．ディー．サール アンド カンパニー 酸化窒素シンターゼ抑制剤として有用なアミジノ誘導体
ES2137512T3 (es) * 1994-05-07 1999-12-16 Astra Ab Derivados de amidina biciclicos como inhibidores de la sintetasa de oxido nitrico.
TW397812B (en) 1995-02-11 2000-07-11 Astra Ab Bicyclic isothiourea derivatives useful in therapy
EE9700207A (et) 1995-08-10 1998-02-16 Astra Aktiebolag Teraapias kasutatavad bitsüklilised amidiini derivaadid
TW458978B (en) * 1995-11-07 2001-10-11 Astra Ab Amidine and isothiourea derivatives as inhibitors of nitric oxide synthase

Also Published As

Publication number Publication date
SK140599A3 (en) 2000-06-12
US6489322B1 (en) 2002-12-03
TR199902720T2 (xx) 2000-02-21
ZA983736B (en) 1998-11-05
ATE221065T1 (de) 2002-08-15
AU734391B2 (en) 2001-06-14
IS5236A (is) 1999-11-01
DE69806750T2 (de) 2003-03-06
EP0983268B1 (en) 2002-07-24
HUP0001873A2 (hu) 2001-01-29
SE9701681D0 (sv) 1997-05-05
ID22885A (id) 1999-12-16
CN1255131A (zh) 2000-05-31
PL336853A1 (en) 2000-07-17
NO995403D0 (no) 1999-11-04
CA2288333A1 (en) 1998-11-12
JP2001523262A (ja) 2001-11-20
NZ500675A (en) 2001-05-25
DE69806750D1 (de) 2002-08-29
IL132678A0 (en) 2001-03-19
MXPA99009882A (es) 2005-11-22
KR20010012228A (ko) 2001-02-15
EP0983268A1 (en) 2000-03-08
EE9900474A (et) 2000-06-15
WO1998050382A1 (en) 1998-11-12
HUP0001873A3 (en) 2001-12-28
NO995403L (no) 2000-01-05
AU7459898A (en) 1998-11-27
BR9809218A (pt) 2000-06-27

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