AR004539A1 - Un metodo para preparar delta (8,9) dehidro estrona o un derivado de la misma. - Google Patents

Un metodo para preparar delta (8,9) dehidro estrona o un derivado de la misma.

Info

Publication number
AR004539A1
AR004539A1 ARP960105050A ARP960105050A AR004539A1 AR 004539 A1 AR004539 A1 AR 004539A1 AR P960105050 A ARP960105050 A AR P960105050A AR P960105050 A ARP960105050 A AR P960105050A AR 004539 A1 AR004539 A1 AR 004539A1
Authority
AR
Argentina
Prior art keywords
derivative
dehydro
estrona
delta
preparing delta
Prior art date
Application number
ARP960105050A
Other languages
English (en)
Original Assignee
Organon Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Organon Nv filed Critical Organon Nv
Publication of AR004539A1 publication Critical patent/AR004539A1/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J1/00Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051Estrane derivatives
    • C07J1/0059Estrane derivatives substituted in position 17 by a keto group
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J1/00Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J1/00Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051Estrane derivatives
    • C07J1/0066Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa
    • C07J1/007Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J1/00Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051Estrane derivatives
    • C07J1/0081Substituted in position 17 alfa and 17 beta
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J51/00Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

La invención se refiere a un método de isomerización de equilina o un derivado de la misma a delta (8,9)-dehidro estrona [delta(8,9)DHE]caracterizado porque equilina o un derivado de la misma es tratada con una sal de litio de etilandiamina oc on amida de litio en dimetilsulfóxido
ARP960105050A 1995-11-06 1996-11-05 Un metodo para preparar delta (8,9) dehidro estrona o un derivado de la misma. AR004539A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP95202990 1995-11-06

Publications (1)

Publication Number Publication Date
AR004539A1 true AR004539A1 (es) 1998-12-16

Family

ID=8220798

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP960105050A AR004539A1 (es) 1995-11-06 1996-11-05 Un metodo para preparar delta (8,9) dehidro estrona o un derivado de la misma.

Country Status (22)

Country Link
US (1) US5739363A (es)
EP (1) EP0771816B1 (es)
JP (1) JP3845482B2 (es)
KR (1) KR100413753B1 (es)
CN (1) CN1120843C (es)
AR (1) AR004539A1 (es)
AT (1) ATE182895T1 (es)
AU (1) AU711636B2 (es)
CA (1) CA2188981C (es)
CZ (1) CZ290448B6 (es)
DE (1) DE69603565T2 (es)
DK (1) DK0771816T3 (es)
ES (1) ES2135843T3 (es)
GR (1) GR3031699T3 (es)
HU (1) HU226695B1 (es)
IL (1) IL119468A (es)
NO (1) NO306349B1 (es)
NZ (1) NZ299673A (es)
PL (1) PL182354B1 (es)
RU (1) RU2161623C2 (es)
TR (1) TR199600882A1 (es)
ZA (1) ZA968873B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5998639A (en) * 1995-11-06 1999-12-07 Akzo Nobel, N.V. Sulfatation of estrogen mixtures
IL124213A (en) * 1997-05-02 2004-12-15 Akzo Nobel Nv Sulfation of estrogen mixtures
AU5209600A (en) * 1999-04-06 2000-10-23 Akzo Nobel N.V. Orally active androgens
US20030158432A1 (en) * 2002-01-08 2003-08-21 Leonard Thomas W. Synthesis of a mixture of sulfated estrogens using a sulfur trioxide complex

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5395831A (en) * 1994-04-08 1995-03-07 American Home Products Corporation Treating cardiac disorders with Δ9(11)-dehydro-8-isoestrone

Also Published As

Publication number Publication date
IL119468A (en) 2000-02-29
CA2188981C (en) 2005-01-25
US5739363A (en) 1998-04-14
RU2161623C2 (ru) 2001-01-10
GR3031699T3 (en) 2000-02-29
KR970027101A (ko) 1997-06-24
PL182354B1 (pl) 2001-12-31
NO964685L (no) 1997-05-07
HUP9603059A3 (en) 1998-11-30
HUP9603059A2 (en) 1997-08-28
EP0771816B1 (en) 1999-08-04
NO964685D0 (no) 1996-11-05
AU7047696A (en) 1997-05-15
ATE182895T1 (de) 1999-08-15
CN1120843C (zh) 2003-09-10
KR100413753B1 (ko) 2004-03-31
EP0771816A3 (en) 1997-11-19
DK0771816T3 (da) 2000-01-31
NO306349B1 (no) 1999-10-25
MX9605380A (es) 1997-10-31
ES2135843T3 (es) 1999-11-01
JPH09169793A (ja) 1997-06-30
PL316826A1 (en) 1997-05-12
NZ299673A (en) 1998-08-26
CZ290448B6 (cs) 2002-07-17
CN1152578A (zh) 1997-06-25
AU711636B2 (en) 1999-10-21
CA2188981A1 (en) 1997-05-07
ZA968873B (en) 1997-05-28
DE69603565D1 (de) 1999-09-09
DE69603565T2 (de) 2000-01-27
JP3845482B2 (ja) 2006-11-15
TR199600882A1 (tr) 1997-05-21
HU9603059D0 (en) 1996-12-30
CZ323996A3 (en) 1997-06-11
EP0771816A2 (en) 1997-05-07
HU226695B1 (en) 2009-06-29
IL119468A0 (en) 1997-01-10

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