AR003138A1 - Composicion farmaceutica para tratar canceres y virus con (1h-1,2,4- triazoles) y composicion de unidad de dosis que la comprende - Google Patents

Composicion farmaceutica para tratar canceres y virus con (1h-1,2,4- triazoles) y composicion de unidad de dosis que la comprende

Info

Publication number
AR003138A1
AR003138A1 ARP960103045A AR10304596A AR003138A1 AR 003138 A1 AR003138 A1 AR 003138A1 AR P960103045 A ARP960103045 A AR P960103045A AR 10304596 A AR10304596 A AR 10304596A AR 003138 A1 AR003138 A1 AR 003138A1
Authority
AR
Argentina
Prior art keywords
composition
pharmaceutical composition
triazoles
viruses
dosage unit
Prior art date
Application number
ARP960103045A
Other languages
English (en)
Original Assignee
Procter & Gamble
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter & Gamble filed Critical Procter & Gamble
Publication of AR003138A1 publication Critical patent/AR003138A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4196—1,2,4-Triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Hematology (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Se revela una composición farmacéutica y correspondiente composición de unidad de dosis, que inhibe el crecimiento de tumores y cánceres en mamíferos,particularmente en humanos y animales de sangre caliente, así como que puede utilizarse paratratar infecciones virales. Estas composiciones comprendenderivados del 1H-1,2,4-triazol de fórmula general (I), donde Z es un alquileno seleccionado entre el grupo que comprende: CH2-CH2-, -CH2-CH2-CH2, -CH(CH3)-CH(CH3)- y -CH2CH(alquilo) dondedic ho alquilo tiene entre 1 y 10 átomos de carbono; y Ar es un miembro seleccionado entre el grupo que comprende fenilo,fenilo sustituido, tienilo, halotienilo, naftilo y fluorenilo. Las sales ácidas de adición del compuesto anterior tambiénpueden incluirse en los alcances deesta invención.
ARP960103045A 1995-06-07 1996-06-07 Composicion farmaceutica para tratar canceres y virus con (1h-1,2,4- triazoles) y composicion de unidad de dosis que la comprende AR003138A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/473,819 US5770616A (en) 1995-06-07 1995-06-07 Pharmaceutical composition for inhibiting the growth of cancers

Publications (1)

Publication Number Publication Date
AR003138A1 true AR003138A1 (es) 1998-07-08

Family

ID=23881121

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP960103045A AR003138A1 (es) 1995-06-07 1996-06-07 Composicion farmaceutica para tratar canceres y virus con (1h-1,2,4- triazoles) y composicion de unidad de dosis que la comprende

Country Status (20)

Country Link
US (4) US5770616A (es)
EP (1) EP0831814A1 (es)
JP (1) JPH11508233A (es)
KR (1) KR19990022619A (es)
CN (1) CN1190344A (es)
AR (1) AR003138A1 (es)
AU (1) AU707077B2 (es)
BR (1) BR9608731A (es)
CA (1) CA2223967A1 (es)
CZ (1) CZ391797A3 (es)
HU (1) HUP9802677A3 (es)
IL (1) IL118425A (es)
NO (1) NO975662L (es)
NZ (1) NZ308391A (es)
PL (1) PL324107A1 (es)
RU (1) RU2177316C2 (es)
SK (1) SK168597A3 (es)
TR (2) TR199801323T2 (es)
WO (1) WO1996040119A1 (es)
ZA (1) ZA964374B (es)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6479526B1 (en) 1995-04-12 2002-11-12 The Procter & Gamble Company Pharmaceutical composition for inhibiting the growth of viruses and cancers
US6262093B1 (en) 1995-04-12 2001-07-17 The Proctor & Gamble Company Methods of treating cancer with benzimidazoles
US6177460B1 (en) 1995-04-12 2001-01-23 The Procter & Gamble Company Method of treatment for cancer or viral infections
US6200992B1 (en) * 1995-06-07 2001-03-13 The Procter & Gamble Company Pharmaceutical composition for inhibiting the growth of cancers
US5770616A (en) 1995-06-07 1998-06-23 The Procter & Gamble Company Pharmaceutical composition for inhibiting the growth of cancers
US6265427B1 (en) 1995-06-07 2001-07-24 The Proctor & Gamble Company Pharmaceutical composition for the method of treating leukemia
US6686391B2 (en) 1995-08-04 2004-02-03 University Of Arizona Foundation N-chlorophenylcarbamate and N-chlorophenylthiocarbamate compositions
US5908855A (en) * 1996-07-16 1999-06-01 The Procter & Gamble Company Compositions for treating viral infections
US5900429A (en) 1997-01-28 1999-05-04 The Procter & Gamble Company Method for inhibiting the growth of cancers
US6506783B1 (en) 1997-05-16 2003-01-14 The Procter & Gamble Company Cancer treatments and pharmaceutical compositions therefor
US6245789B1 (en) 1998-05-19 2001-06-12 The Procter & Gamble Company HIV and viral treatment
US6423734B1 (en) 1999-08-13 2002-07-23 The Procter & Gamble Company Method of preventing cancer
US6380232B1 (en) 2000-09-26 2002-04-30 The Procter & Gamble Company Benzimidazole urea derivatives, and pharmaceutical compositions and unit dosages thereof
US6407105B1 (en) 2000-09-26 2002-06-18 The Procter & Gamble Company Compounds and methods for use thereof in the treatment of cancer or viral infections
US6608096B1 (en) * 2000-09-26 2003-08-19 University Of Arizona Foundation Compounds and methods for use thereof in the treatment of cancer or viral infections
US6462062B1 (en) * 2000-09-26 2002-10-08 The Procter & Gamble Company Compounds and methods for use thereof in the treatment of cancer or viral infections
US6515074B2 (en) * 2001-01-22 2003-02-04 Delphi Technologies, Inc. Thermoplastic polymer alloy compositions and process for manufacture thereof
CN100334084C (zh) * 2005-04-26 2007-08-29 武汉大学 联三唑化合物及其制备方法和用途
WO2007005644A2 (en) * 2005-07-01 2007-01-11 Concert Pharmaceuticals Inc. Novel aryloxypropanamines
CA2629800A1 (en) * 2005-11-23 2007-05-31 Thomas G. Gant Substituted aryloxypropylamines with serotoninergic and/or norepinephrinergic activity

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US4160838A (en) * 1977-06-02 1979-07-10 Janssen Pharmaceutica N.V. Antimicrobial and plant-growth-regulating triazole derivatives
GB2078719B (en) * 1980-06-02 1984-04-26 Ici Ltd Heterocyclic compounds
DE3262386D1 (en) * 1981-06-06 1985-03-28 Pfizer Ltd Antifungal agents, processes for their preparation, and pharmaceutical compositions containing them
US4490540A (en) * 1981-09-14 1984-12-25 Janssen Pharmaceutica N.V. (2-Aryl-4-phenylthioalkyl-1,3-dioxolan-2-ylmethyl)azole derivatives
DE3238903A1 (de) * 1982-10-21 1984-04-26 Bayer Ag, 5090 Leverkusen Antivirales mittel
DE3511411A1 (de) * 1985-03-29 1986-10-02 Basf Ag, 6700 Ludwigshafen Verwendung von azolylmethyloxiranen zur bekaempfung von viralen erkrankungen
EP0196855A3 (en) * 1985-03-29 1989-04-12 Pfizer Inc. Tioconazole and related compounds for prevention of sexually transmitted diseases and control of herpetic infections
DE3511409A1 (de) * 1985-03-29 1986-10-02 Basf Ag, 6700 Ludwigshafen Herstellung von arzneimitteln gegen viruserkrankungen
US5211736A (en) * 1988-05-09 1993-05-18 Uniroyal Chemical Company, Inc. Azole derivatives of spiroheterocycles
DE3837463A1 (de) * 1988-11-04 1990-05-10 Bayer Ag Substituierte bisazole, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
JPH02257929A (ja) * 1989-03-09 1990-10-18 Makutaa Kk 生体透過率測定器
US5114951A (en) * 1989-04-11 1992-05-19 Burroughs Wellcome Company Agents for combating multiple drug resistance
BE1004029A6 (nl) * 1990-11-22 1992-09-08 Mol Omer De Farmaceutische samenstelling en farmaceutische set voor het behandelen van kanker.
UA41295C2 (uk) 1991-09-02 2001-09-17 Яманугі Фармасетікл Ко., Лтд Триазолілзаміщені третинні амінні сполуки або їх солі як інгібітор ароматази та фармацевтична композиція на їх основі
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US5565478A (en) * 1994-03-14 1996-10-15 The United States Of America As Represented By The Department Of Health & Human Services Combination therapy using signal transduction inhibitors with paclitaxel and other taxane analogs
US5629341A (en) 1995-04-12 1997-05-13 The Procter & Gamble Company Pharmaceutical composition for inhibiting the growth of viruses and cancers
ZA962880B (en) 1995-04-12 1997-03-17 Procter & Gamble A pharmaceutical composition for inhibiting the growth of viruses and cancers
TR199701151T1 (xx) 1995-04-12 1998-03-21 The Procter & Gamble Company Vir�sler ve kanserlerin geli�mesini �nlemeye mahsus, N-klorofenil karbamatlar� ve N-klorofeniltiokarbamatlar� i�eren bir farmas�tik bile�im.
NZ305784A (en) 1995-04-12 2001-03-30 Procter & Gamble Benzimidazole containing medicaments for treating cancers, tumors and viral infections
ZA962879B (en) 1995-04-12 1997-03-17 Procter & Gamble A pharmaceutical composition for inhibiting the growth of viruses and cancers
US5656615A (en) 1995-04-12 1997-08-12 The Procter & Gamble Company Pharmaceutical composition for inhibiting the growth of cancers and viruses in mammals
US5665713A (en) 1995-04-12 1997-09-09 Procter & Gamble Company Pharmaceutical composition for inhibiting the growth of viruses and cancers
US6200992B1 (en) 1995-06-07 2001-03-13 The Procter & Gamble Company Pharmaceutical composition for inhibiting the growth of cancers
US5770616A (en) 1995-06-07 1998-06-23 The Procter & Gamble Company Pharmaceutical composition for inhibiting the growth of cancers
US5665751A (en) * 1995-06-07 1997-09-09 The Procter & Gamble Company Pharmaceutical composition for inhibiting the growth of cancers
EP0831816A1 (en) 1995-06-07 1998-04-01 The Procter & Gamble Company Use of benzimidazoles for the manufacture of a medicament for the treatment of leukemia
MX9707809A (es) 1995-06-07 1998-01-31 Procter & Gamble Una composicion farmaceutica que contiene bencimidazol para inhibir el crecimiento de canceres.
WO1997005870A2 (en) 1995-08-03 1997-02-20 The Procter & Gamble Company Use of griseofulvin for inhibiting the growth of cancers
NZ503921A (en) 1995-08-04 2002-03-01 Procter & Gamble Use of fluconazole mixed with chemotherapeutic agents for inhibiting the growth of cancers or tumors
US5908855A (en) 1996-07-16 1999-06-01 The Procter & Gamble Company Compositions for treating viral infections
US5900429A (en) 1997-01-28 1999-05-04 The Procter & Gamble Company Method for inhibiting the growth of cancers
PE11499A1 (es) 1997-05-16 1999-03-01 Procter & Gamble Tratamiento del hiv y cancer
US6506783B1 (en) 1997-05-16 2003-01-14 The Procter & Gamble Company Cancer treatments and pharmaceutical compositions therefor
US6245789B1 (en) 1998-05-19 2001-06-12 The Procter & Gamble Company HIV and viral treatment

Also Published As

Publication number Publication date
WO1996040119A1 (en) 1996-12-19
IL118425A (en) 2001-05-20
HUP9802677A3 (en) 1999-11-29
US6228876B1 (en) 2001-05-08
NO975662D0 (no) 1997-12-05
RU2177316C2 (ru) 2001-12-27
NO975662L (no) 1998-02-09
IL118425A0 (en) 1996-09-12
EP0831814A1 (en) 1998-04-01
US5770616A (en) 1998-06-23
JPH11508233A (ja) 1999-07-21
SK168597A3 (en) 1998-12-02
US6025377A (en) 2000-02-15
AU707077B2 (en) 1999-07-01
TR199801323T2 (xx) 1998-09-21
NZ308391A (en) 2000-05-26
PL324107A1 (en) 1998-05-11
BR9608731A (pt) 1999-06-29
HUP9802677A2 (hu) 1999-08-30
AU5801996A (en) 1996-12-30
KR19990022619A (ko) 1999-03-25
CZ391797A3 (cs) 1998-05-13
CN1190344A (zh) 1998-08-12
US5872142A (en) 1999-02-16
TR199701534T1 (xx) 1998-02-21
ZA964374B (en) 1997-02-17
CA2223967A1 (en) 1996-12-19

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