AP363A - Heteroanthracycline antitumor analogs. - Google Patents

Heteroanthracycline antitumor analogs. Download PDF

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Publication number
AP363A
AP363A APAP/P/1992/000361A AP9200361A AP363A AP 363 A AP363 A AP 363A AP 9200361 A AP9200361 A AP 9200361A AP 363 A AP363 A AP 363A
Authority
AP
ARIPO
Prior art keywords
group
formula
alkyl
hydrogen
amino
Prior art date
Application number
APAP/P/1992/000361A
Other languages
English (en)
Other versions
AP9200361A0 (en
Inventor
Giorgio Attardo
Bernard Belleau
Original Assignee
Iaf Biochem Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/751,092 external-priority patent/US5348946A/en
Application filed by Iaf Biochem Int filed Critical Iaf Biochem Int
Publication of AP9200361A0 publication Critical patent/AP9200361A0/xx
Application granted granted Critical
Publication of AP363A publication Critical patent/AP363A/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C313/00—Sulfinic acids; Sulfenic acids; Halides, esters or anhydrides thereof; Amides of sulfinic or sulfenic acids, i.e. compounds having singly-bound oxygen atoms of sulfinic or sulfenic groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C313/08—Sulfenic acids; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/56—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds
    • C07C45/57—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom
    • C07C45/60—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom in six-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00—Compounds having —CHO groups
    • C07C47/52—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
    • C07C47/575—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
    • C07D319/06—1,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/72—Benzo[c]thiophenes; Hydrogenated benzo[c]thiophenes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
APAP/P/1992/000361A 1991-02-28 1992-02-18 Heteroanthracycline antitumor analogs. AP363A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US66137691A 1991-02-28 1991-02-28
US07/751,092 US5348946A (en) 1991-02-28 1991-08-28 Heteroanthracycline antitumor analogs

Publications (2)

Publication Number Publication Date
AP9200361A0 AP9200361A0 (en) 1992-04-30
AP363A true AP363A (en) 1994-09-23

Family

ID=27098299

Family Applications (1)

Application Number Title Priority Date Filing Date
APAP/P/1992/000361A AP363A (en) 1991-02-28 1992-02-18 Heteroanthracycline antitumor analogs.

Country Status (12)

Country Link
EP (1) EP0502661A2 (enrdf_load_stackoverflow)
JP (1) JPH06505007A (enrdf_load_stackoverflow)
AP (1) AP363A (enrdf_load_stackoverflow)
AU (1) AU1230992A (enrdf_load_stackoverflow)
CA (1) CA2104768A1 (enrdf_load_stackoverflow)
FI (1) FI933777L (enrdf_load_stackoverflow)
IE (1) IE920480A1 (enrdf_load_stackoverflow)
IL (1) IL100962A0 (enrdf_load_stackoverflow)
MX (1) MX9200834A (enrdf_load_stackoverflow)
NO (1) NO933064L (enrdf_load_stackoverflow)
NZ (1) NZ241606A (enrdf_load_stackoverflow)
WO (1) WO1992015601A2 (enrdf_load_stackoverflow)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL110289A (en) * 1993-08-06 1998-01-04 Policlinico San Matteo Istitut Pharmaceutical preparations containing 4-iodo-4-deoxydoxorubicin for the treatment of amyloidosis
US9486457B2 (en) 2010-02-23 2016-11-08 The Regents Of The University Of California Use of cinnabarinic acid as a modulator of immune responses in autoimmune disorders
TW202023625A (zh) 2018-08-23 2020-07-01 美商西雅圖遺傳學公司 抗tigit抗體

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CS158975B1 (enrdf_load_stackoverflow) * 1971-11-18 1974-12-27
FR2444701A1 (fr) * 1978-12-21 1980-07-18 Bbc Brown Boveri & Cie Melange de cristaux liquides renfermant un colorant anthraquinonique

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CS158976B1 (enrdf_load_stackoverflow) * 1971-11-25 1974-12-27
US4585760A (en) * 1981-07-16 1986-04-29 American Cyanamid Company Dimethylfurano heterocyclic analogs of daunomycin
DE3150629A1 (de) * 1981-12-21 1983-06-30 Basf Ag, 6700 Ludwigshafen Verfahren zur herstellung von 1,2-benzisothiazolin-3-onen
US4530572A (en) * 1982-12-30 1985-07-23 Minnesota Mining And Manufacturing Company Substituted anthraquinone-type isotropic dyes for liquid crystal display devices
CA1269370C (en) * 1986-11-17 1990-05-22 SULFONO AND SULFOXO ANALOGS OF DAUNOMYCIN AND ADRIAMYCIN
GB2225781A (en) * 1988-05-13 1990-06-13 Erba Carlo Spa 10-Noranthracyclines

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CS158975B1 (enrdf_load_stackoverflow) * 1971-11-18 1974-12-27
FR2444701A1 (fr) * 1978-12-21 1980-07-18 Bbc Brown Boveri & Cie Melange de cristaux liquides renfermant un colorant anthraquinonique

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Chemical Abstracts, vol. 84, 1976, Columbus, Ohio, US; see page 503, column 1, abstract 89900y, & CS,B1, 158975 (J. MAJER et al.) 15 July 1975 *

Also Published As

Publication number Publication date
CA2104768A1 (en) 1992-08-29
IL100962A0 (en) 1992-11-15
NO933064L (no) 1993-08-30
FI933777A7 (fi) 1993-08-27
FI933777A0 (fi) 1993-08-27
WO1992015601A3 (en) 1992-10-29
EP0502661A3 (enrdf_load_stackoverflow) 1994-03-30
FI933777L (fi) 1993-08-27
MX9200834A (es) 1992-10-01
IE920480A1 (en) 1992-09-09
NO933064D0 (no) 1993-08-27
AU1230992A (en) 1992-10-06
JPH06505007A (ja) 1994-06-09
WO1992015601A2 (en) 1992-09-17
EP0502661A2 (en) 1992-09-09
AP9200361A0 (en) 1992-04-30
NZ241606A (en) 1994-08-26

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