AP2444A - New benzothiazinone derivatives and their use as antibacterial agents - Google Patents
New benzothiazinone derivatives and their use as antibacterial agentsInfo
- Publication number
- AP2444A AP2444A AP2008004723A AP2008004723A AP2444A AP 2444 A AP2444 A AP 2444A AP 2008004723 A AP2008004723 A AP 2008004723A AP 2008004723 A AP2008004723 A AP 2008004723A AP 2444 A AP2444 A AP 2444A
- Authority
- AP
- ARIPO
- Prior art keywords
- antibacterial agents
- new
- benzothiazinone derivatives
- derivatives
- new benzothiazinone
- Prior art date
Links
- MJNPHLBKHKJDEF-UHFFFAOYSA-N 2h-1$l^{4},2-benzothiazine 1-oxide Chemical class C1=CC=C2S(=O)NC=CC2=C1 MJNPHLBKHKJDEF-UHFFFAOYSA-N 0.000 title 1
- 239000003242 anti bacterial agent Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/5415—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/08—Antibacterial agents for leprosy
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
- C07D491/113—Spiro-condensed systems with two or more oxygen atoms as ring hetero atoms in the oxygen-containing ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pulmonology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/EP2006/004942 WO2007134625A1 (fr) | 2006-05-24 | 2006-05-24 | Nouveaux dÉrivÉs de la benzothiazinone et leur utilisation en tant qu'agents ANTIBACTÉRIENS |
Publications (2)
Publication Number | Publication Date |
---|---|
AP2008004723A0 AP2008004723A0 (en) | 2008-12-31 |
AP2444A true AP2444A (en) | 2012-08-31 |
Family
ID=37595033
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AP2008004723A AP2444A (en) | 2006-05-24 | 2006-05-24 | New benzothiazinone derivatives and their use as antibacterial agents |
Country Status (24)
Country | Link |
---|---|
US (2) | US7863268B2 (fr) |
EP (1) | EP2029583B1 (fr) |
JP (1) | JP5068813B2 (fr) |
KR (1) | KR101314999B1 (fr) |
CN (1) | CN101472922B (fr) |
AP (1) | AP2444A (fr) |
AT (1) | ATE470667T1 (fr) |
AU (1) | AU2006343832B2 (fr) |
BR (1) | BRPI0621693B8 (fr) |
CA (1) | CA2652841C (fr) |
CR (1) | CR10519A (fr) |
CY (1) | CY1110769T1 (fr) |
DE (1) | DE602006014885D1 (fr) |
DK (1) | DK2029583T3 (fr) |
EA (1) | EA015910B1 (fr) |
ES (1) | ES2345902T3 (fr) |
IL (1) | IL195453A (fr) |
MX (1) | MX2008014958A (fr) |
NZ (1) | NZ573833A (fr) |
PL (1) | PL2029583T3 (fr) |
PT (1) | PT2029583E (fr) |
SI (1) | SI2029583T1 (fr) |
TN (1) | TNSN08474A1 (fr) |
WO (1) | WO2007134625A1 (fr) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2029583B1 (fr) | 2006-05-24 | 2010-06-09 | Leibniz-Institut für Naturstoff-Forschung und Infektionsbiologie e.V. Hans-Knöll-Institut | Nouveaux dérivés de la benzothiazinone et leur utilisation en tant qu'agents antibactériens |
EP2020406A1 (fr) * | 2007-07-16 | 2009-02-04 | Leibniz-Institut für Naturstoff-Forschung und Infektionsbiologie e.V. Hans-Knöll-Institut | Nouveaux composés antimicrobiens, leur synthèse et utilisation pour le traitement des infections liées aux mammifères |
CN101971031A (zh) | 2008-02-13 | 2011-02-09 | 森迪奈尔Ch有限责任公司 | 用于治疗结核病的有效的新药物靶标 |
EP2380886A1 (fr) | 2010-04-23 | 2011-10-26 | Vadim A. Makarov | Procédé de préparation de 2-aminosubstituted 1,3-benzothiazine-4-ones |
CN103221399A (zh) * | 2010-11-19 | 2013-07-24 | 洛桑联邦理工学院(Epfl) | 2-哌嗪-1-基-4h-1,3-苯并噻嗪-4-酮衍生物及其用于治疗哺乳动物感染的用途 |
EP2468746A1 (fr) | 2010-12-23 | 2012-06-27 | The University of Queensland | Composés benzothiazinone et leur utilisation comme anti-tuberculeux |
US8486717B2 (en) | 2011-01-18 | 2013-07-16 | Symbolics, Llc | Lateral flow assays using two dimensional features |
CN102276598B (zh) * | 2011-05-27 | 2014-11-05 | 四川大学 | 苯并噻嗪硫酮衍生物及其制备方法和用途 |
CN102367239B (zh) * | 2011-07-20 | 2015-10-28 | 沈阳药科大学 | 2-芳基-2,3-二氢-4h-1,3-苯并噻嗪-4-酮衍生物及其用途 |
EP2570413A1 (fr) | 2011-09-15 | 2013-03-20 | The University Of Queensland | Dérivés de benzothiazinone en tant qu'agents anti-tuberculose |
CN103508980B (zh) * | 2012-06-14 | 2016-07-06 | 四川大学 | 苯并噻嗪-4-酮衍生物及其制备方法和用途 |
US9874556B2 (en) | 2012-07-18 | 2018-01-23 | Symbolics, Llc | Lateral flow assays using two dimensional features |
CN104211708B (zh) * | 2013-05-29 | 2018-08-24 | 中国医学科学院药物研究所 | 苯并噁嗪酮衍生物及其作为抗菌剂的应用 |
WO2015038978A1 (fr) | 2013-09-13 | 2015-03-19 | Symbolics, Llc | Measures d'écoulement latéral utilisant des motifs d'essai bidimensionnel et de lecture de signal témoin |
CN105705486B (zh) | 2013-11-18 | 2019-03-01 | 格里洛工厂股份有限公司 | 用于自烷烃和发烟硫酸制备烷基磺酸的新型引发剂 |
DE102014012546A1 (de) * | 2014-09-26 | 2016-03-31 | Martin-Luther-Universität Halle-Wittenberg | Antimykobakteriell wirksame Substanzen, Verfahren zu ihrer Herstellung und deren Verwendung |
EP3072889A1 (fr) | 2015-03-23 | 2016-09-28 | Ecole Polytechnique Federale De Lausanne (Epfl) | Dàrivés de 2-homopipérazine-1-yl-4h-1,3-benzothiazine-4-one et procédé pour la préparation d'hydrochlorures de 2- (homo) pipérazine 1,3-benzothiazine-4-one |
CN105622596B (zh) * | 2016-02-19 | 2018-10-30 | 浙江司太立制药股份有限公司 | 含有烷氧亚胺基氮杂环片段的苯并噻嗪-4-酮类化合物及其制备方法 |
CN105669664B (zh) * | 2016-02-19 | 2019-05-10 | 浙江司太立制药股份有限公司 | 含有碱性氮杂环片段的苯并噻嗪-4-酮类化合物及其制备方法 |
JP7125941B2 (ja) * | 2016-09-22 | 2022-08-25 | ライプニッツ-インスティトゥート フュア ナチュルストフ-フォルスチュング ウント インフェクションズバイオロジー エー.フェー. ハンス-ノール インスティトゥート (ハーカーイー) | 新しい抗微生物化合物、哺乳動物感染症の治療のためのそれらの使用及び新しい代謝メカニズム |
RU2663848C1 (ru) * | 2018-03-23 | 2018-08-10 | Федеральное государственное бюджетное учреждение науки Институт органического синтеза им. И.Я. Постовского Уральского отделения Российской академии наук (ИОС УрО РАН) | 5-Фтор-2-(4-этоксикарбонилпиперазин-1-ил)-1,3-бензотиазин-4-он, обладающий противотуберкулезной активностью |
CN111269197A (zh) * | 2020-04-08 | 2020-06-12 | 苏州大学 | 苯并噻嗪酮化合物及其制备方法与作为抗结核药物的应用 |
CN113121521B (zh) * | 2021-03-26 | 2022-11-04 | 苏州大学 | 6-位三氟甲基取代的苯并噻嗪酮衍生物及其制备方法与应用 |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3522247A (en) * | 1967-11-07 | 1970-07-28 | Pfizer & Co C | 2-amino-6,7-disubstituted-4h-1,3-benzothiazine-4-ones as bronchodilators |
WO2005092872A1 (fr) * | 2004-03-26 | 2005-10-06 | Arpida A/S | Inhibiteurs de peptide deformylase |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3470168A (en) * | 1967-03-31 | 1969-09-30 | American Home Prod | 2-substituted-4h-1,3-benzothiazin-4-one derivatives |
GB8611617D0 (en) | 1986-05-13 | 1986-06-18 | Shell Int Research | Fungicides |
AU3704400A (en) | 1999-03-04 | 2000-09-21 | E.I. Du Pont De Nemours And Company | Fused bicyclic oxazinone and thiazinone fungicides |
EP1312607A1 (fr) | 2001-11-17 | 2003-05-21 | MEDAC GmbH | Dérivés dithiocarbamiques et leur utilisation comme agents antibactériens |
AU2003289176A1 (en) | 2002-12-05 | 2004-07-29 | Takeda Pharmaceutical Company Limited | 1,3-benzothiazinone derivatives, process for producing the same and use thereof |
EP2029583B1 (fr) | 2006-05-24 | 2010-06-09 | Leibniz-Institut für Naturstoff-Forschung und Infektionsbiologie e.V. Hans-Knöll-Institut | Nouveaux dérivés de la benzothiazinone et leur utilisation en tant qu'agents antibactériens |
-
2006
- 2006-05-24 EP EP06743049A patent/EP2029583B1/fr active Active
- 2006-05-24 PL PL06743049T patent/PL2029583T3/pl unknown
- 2006-05-24 WO PCT/EP2006/004942 patent/WO2007134625A1/fr active Application Filing
- 2006-05-24 PT PT06743049T patent/PT2029583E/pt unknown
- 2006-05-24 JP JP2009511341A patent/JP5068813B2/ja active Active
- 2006-05-24 AP AP2008004723A patent/AP2444A/xx active
- 2006-05-24 CA CA2652841A patent/CA2652841C/fr not_active Expired - Fee Related
- 2006-05-24 BR BRPI0621693A patent/BRPI0621693B8/pt active IP Right Grant
- 2006-05-24 KR KR1020087031308A patent/KR101314999B1/ko active IP Right Grant
- 2006-05-24 DK DK06743049.6T patent/DK2029583T3/da active
- 2006-05-24 US US12/227,655 patent/US7863268B2/en active Active
- 2006-05-24 AT AT06743049T patent/ATE470667T1/de active
- 2006-05-24 CN CN2006800551120A patent/CN101472922B/zh active Active
- 2006-05-24 NZ NZ573833A patent/NZ573833A/en not_active IP Right Cessation
- 2006-05-24 MX MX2008014958A patent/MX2008014958A/es active IP Right Grant
- 2006-05-24 AU AU2006343832A patent/AU2006343832B2/en not_active Ceased
- 2006-05-24 ES ES06743049T patent/ES2345902T3/es active Active
- 2006-05-24 DE DE602006014885T patent/DE602006014885D1/de active Active
- 2006-05-24 SI SI200630745T patent/SI2029583T1/sl unknown
- 2006-05-24 EA EA200870564A patent/EA015910B1/ru not_active IP Right Cessation
-
2008
- 2008-11-21 TN TNP2008000474A patent/TNSN08474A1/en unknown
- 2008-11-23 IL IL195453A patent/IL195453A/en active IP Right Grant
- 2008-12-17 CR CR10519A patent/CR10519A/es unknown
-
2010
- 2010-09-07 CY CY20101100815T patent/CY1110769T1/el unknown
- 2010-12-22 US US12/976,905 patent/US20110160193A1/en not_active Abandoned
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3522247A (en) * | 1967-11-07 | 1970-07-28 | Pfizer & Co C | 2-amino-6,7-disubstituted-4h-1,3-benzothiazine-4-ones as bronchodilators |
WO2005092872A1 (fr) * | 2004-03-26 | 2005-10-06 | Arpida A/S | Inhibiteurs de peptide deformylase |
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