AP2386A - Quinoline derivatives as antibacterial agents. - Google Patents

Quinoline derivatives as antibacterial agents.

Info

Publication number
AP2386A
AP2386A AP2008004303A AP2008004303A AP2386A AP 2386 A AP2386 A AP 2386A AP 2008004303 A AP2008004303 A AP 2008004303A AP 2008004303 A AP2008004303 A AP 2008004303A AP 2386 A AP2386 A AP 2386A
Authority
AP
ARIPO
Prior art keywords
antibacterial agents
quinoline derivatives
quinoline
derivatives
antibacterial
Prior art date
Application number
AP2008004303A
Other languages
English (en)
Inventor
Koenraad Jozef Lodewijk Marcel Andries
Anil Koul
Jerome Emile Georges Guillemont
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34940244&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AP2386(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Application granted granted Critical
Publication of AP2386A publication Critical patent/AP2386A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/04—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to the ring carbon atoms
    • C07D215/06—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to the ring carbon atoms having only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AP2008004303A 2005-06-28 2006-06-26 Quinoline derivatives as antibacterial agents. AP2386A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP05105762 2005-06-28

Publications (1)

Publication Number Publication Date
AP2386A true AP2386A (en) 2012-03-23

Family

ID=34940244

Family Applications (1)

Application Number Title Priority Date Filing Date
AP2008004303A AP2386A (en) 2005-06-28 2006-06-26 Quinoline derivatives as antibacterial agents.

Country Status (32)

Country Link
US (1) US8841321B2 (pl)
EP (1) EP1898914B1 (pl)
JP (1) JP5193858B2 (pl)
KR (1) KR101329585B1 (pl)
CN (1) CN101247811B (pl)
AP (1) AP2386A (pl)
AR (1) AR054626A1 (pl)
AU (1) AU2006263883B2 (pl)
BR (1) BRPI0612498A8 (pl)
CA (1) CA2612619C (pl)
CY (1) CY1113579T1 (pl)
DK (1) DK1898914T3 (pl)
EA (1) EA014423B1 (pl)
ES (1) ES2393203T3 (pl)
HK (1) HK1122730A1 (pl)
HR (1) HRP20120912T1 (pl)
IL (1) IL188393A0 (pl)
JO (1) JO2752B1 (pl)
ME (1) ME01484B (pl)
MX (1) MX2008000081A (pl)
MY (1) MY153291A (pl)
NO (1) NO342701B1 (pl)
NZ (1) NZ564379A (pl)
PA (1) PA8683801A1 (pl)
PL (1) PL1898914T3 (pl)
PT (1) PT1898914E (pl)
RS (1) RS52517B (pl)
SI (1) SI1898914T1 (pl)
TW (1) TWI387457B (pl)
UA (1) UA92175C2 (pl)
WO (1) WO2007000435A1 (pl)
ZA (1) ZA200711165B (pl)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JO2683B1 (en) * 2006-12-06 2013-03-03 جانسين فارماسوتيكا ان. في Quinoline antibacterial derivatives
JO2970B1 (en) 2006-12-06 2016-03-15 جانسين فارماسوتيكا ان. في Quinoline antibacterial derivatives
CN104254527B (zh) 2012-04-27 2017-05-31 詹森药业有限公司 抗菌的喹啉衍生物
AU2013254670B2 (en) 2012-04-27 2017-03-30 Janssen Pharmaceutica Nv Antibacterial quinoline derivatives
CN107001272A (zh) 2014-12-23 2017-08-01 阿尔比马尔公司 用于合成烷基化甲吡酮类似物的一步法
CN106928139B (zh) * 2017-05-08 2019-06-25 福建省微生物研究所 一种贝达喹啉杂质的合成方法

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004011436A1 (en) * 2002-07-25 2004-02-05 Janssen Pharmaceutica N.V. Quinoline derivatives and their use as mycobacterial inhibitors
WO2005033108A1 (en) * 2003-09-22 2005-04-14 Janssen Pharmaceutica, N.V. 7-amino alkylidenyl-heterocyclic quinolones and naphthyridones
WO2005117875A1 (en) * 2004-05-28 2005-12-15 Janssen Pharmaceutica N.V. Use of substituted quinoline derivatives for the treatment of drug resistant mycobacterial diseases
WO2006067048A1 (en) * 2004-12-24 2006-06-29 Janssen Pharmaceutica N.V. Quinoline derivatives for the treatment of latent tuberculosis

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19937116A1 (de) * 1999-08-06 2001-02-08 Bayer Ag Moxifloxacin Kochsalzformulierung
WO2007000434A1 (en) 2005-06-28 2007-01-04 Janssen Pharmaceutica N.V. Quinoline derivatives as antibacterial agents

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004011436A1 (en) * 2002-07-25 2004-02-05 Janssen Pharmaceutica N.V. Quinoline derivatives and their use as mycobacterial inhibitors
WO2005033108A1 (en) * 2003-09-22 2005-04-14 Janssen Pharmaceutica, N.V. 7-amino alkylidenyl-heterocyclic quinolones and naphthyridones
WO2005117875A1 (en) * 2004-05-28 2005-12-15 Janssen Pharmaceutica N.V. Use of substituted quinoline derivatives for the treatment of drug resistant mycobacterial diseases
WO2006067048A1 (en) * 2004-12-24 2006-06-29 Janssen Pharmaceutica N.V. Quinoline derivatives for the treatment of latent tuberculosis

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
DESAI P K ET AL *

Also Published As

Publication number Publication date
MY153291A (en) 2015-01-29
EP1898914A1 (en) 2008-03-19
PL1898914T3 (pl) 2013-01-31
BRPI0612498A2 (pt) 2010-11-23
TW200740437A (en) 2007-11-01
JO2752B1 (en) 2014-03-15
MX2008000081A (es) 2008-03-24
NZ564379A (en) 2010-11-26
EA200800154A1 (ru) 2008-10-30
JP5193858B2 (ja) 2013-05-08
JP2008543964A (ja) 2008-12-04
AR054626A1 (es) 2007-07-04
US8841321B2 (en) 2014-09-23
NO342701B1 (no) 2018-07-09
DK1898914T3 (da) 2012-11-26
HK1122730A1 (en) 2009-05-29
CA2612619A1 (en) 2007-01-04
EP1898914B1 (en) 2012-08-15
PA8683801A1 (es) 2007-01-17
US20100048585A1 (en) 2010-02-25
KR101329585B1 (ko) 2013-11-15
HRP20120912T1 (hr) 2012-12-31
IL188393A0 (en) 2008-08-07
CY1113579T1 (el) 2016-06-22
PT1898914E (pt) 2012-11-20
NO20080501L (no) 2008-02-28
KR20080021156A (ko) 2008-03-06
ME01484B (me) 2014-04-20
AU2006263883A1 (en) 2007-01-04
CA2612619C (en) 2015-12-01
AU2006263883B2 (en) 2012-12-13
CN101247811A (zh) 2008-08-20
CN101247811B (zh) 2013-01-02
EA014423B1 (ru) 2010-12-30
BRPI0612498A8 (pt) 2018-01-02
TWI387457B (zh) 2013-03-01
WO2007000435A1 (en) 2007-01-04
ZA200711165B (en) 2011-05-25
ES2393203T3 (es) 2012-12-19
UA92175C2 (ru) 2010-10-11
RS52517B (en) 2013-04-30
SI1898914T1 (sl) 2013-01-31

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