AP2157A - 2-substituted pyrimidines. - Google Patents

2-substituted pyrimidines.

Info

Publication number
AP2157A
AP2157A AP2006003497A AP2006003497A AP2157A AP 2157 A AP2157 A AP 2157A AP 2006003497 A AP2006003497 A AP 2006003497A AP 2006003497 A AP2006003497 A AP 2006003497A AP 2157 A AP2157 A AP 2157A
Authority
AP
ARIPO
Prior art keywords
substituted pyrimidines
pyrimidines
substituted
Prior art date
Application number
AP2006003497A
Other languages
English (en)
Other versions
AP2006003497A0 (en
Inventor
Anja Dr Schwogler
Markus Dr Gewehr
Bernd Dr Mueller
Original Assignee
Basf Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Ag filed Critical Basf Ag
Publication of AP2006003497A0 publication Critical patent/AP2006003497A0/xx
Application granted granted Critical
Publication of AP2157A publication Critical patent/AP2157A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/42—One nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/30—Halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AP2006003497A 2003-07-24 2004-07-15 2-substituted pyrimidines. AP2157A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10333857 2003-07-24
DE10357714 2003-12-09
PCT/EP2004/007877 WO2005012261A1 (fr) 2003-07-24 2004-07-15 Pyrimidines substituees en 2

Publications (2)

Publication Number Publication Date
AP2006003497A0 AP2006003497A0 (en) 2006-02-28
AP2157A true AP2157A (en) 2010-09-13

Family

ID=34117367

Family Applications (1)

Application Number Title Priority Date Filing Date
AP2006003497A AP2157A (en) 2003-07-24 2004-07-15 2-substituted pyrimidines.

Country Status (30)

Country Link
US (1) US7375108B2 (fr)
EP (1) EP1651618B1 (fr)
JP (1) JP2006528603A (fr)
KR (1) KR20060052857A (fr)
AP (1) AP2157A (fr)
AR (1) AR045100A1 (fr)
AT (1) ATE350370T1 (fr)
AU (1) AU2004261373B8 (fr)
BR (1) BRPI0412891A (fr)
CA (1) CA2532718A1 (fr)
CO (1) CO5660292A2 (fr)
CR (1) CR8184A (fr)
CY (1) CY1106391T1 (fr)
DE (1) DE502004002570D1 (fr)
DK (1) DK1651618T3 (fr)
EA (1) EA010566B1 (fr)
EC (1) ECSP066278A (fr)
ES (1) ES2279395T3 (fr)
HR (1) HRP20070057T3 (fr)
IL (1) IL172848A0 (fr)
MA (1) MA27949A1 (fr)
MX (1) MXPA06000038A (fr)
NZ (1) NZ545103A (fr)
PE (1) PE20050882A1 (fr)
PL (1) PL1651618T3 (fr)
PT (1) PT1651618E (fr)
SI (1) SI1651618T1 (fr)
TW (1) TW200516075A (fr)
UY (1) UY28436A1 (fr)
WO (1) WO2005012261A1 (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080132522A1 (en) * 2004-07-14 2008-06-05 Basf Aktiengesellschaft 2-Substituted Pyrimidines, Method for Their Production and Their Use for Controlling Pathogenic Fungi
CL2007002231A1 (es) * 2006-08-02 2008-04-11 Basf Ag Uso de compuestos derivados de 5-(het) arilpirimidina para combatir hongos daninos; compuestos derivados de 5-(het) arilpirimidina; agente fungicida; y agente farmaceutico.
PT2640709T (pt) * 2010-11-16 2016-07-13 Acetylon Pharmaceuticals Inc Compostos de pirimidina hidroxiamida como inibidores de proteína desacetilase e métodos de utilização dos mesmos
EP3054952B1 (fr) 2013-10-08 2022-10-26 Acetylon Pharmaceuticals, Inc. Combinaisons d'inhibiteurs d'histone désacétylase 6 et de l'inhibiteur d'her2 lapatinib pour le traitement du cancer du sein
US9278963B2 (en) 2013-10-10 2016-03-08 Acetylon Pharmaceuticals, Inc. Pyrimidine hydroxy amide compounds as histone deacetylase inhibitors
EP3060217B1 (fr) 2013-10-24 2022-06-08 Mayo Foundation for Medical Education and Research Traitement des maladies polykystiques avec un inhibiteur hdac6
CA2932411A1 (fr) 2013-12-03 2015-06-11 Acetylon Pharmaceuticals, Inc. Combinaisons d'inhibiteurs d'histone desacetylase et medicaments immunomodulateurs
US9464073B2 (en) 2014-02-26 2016-10-11 Acetylon Pharmaceuticals, Inc. Pyrimidine hydroxy amide compounds as HDAC6 selective inhibitors
EP3166603B1 (fr) 2014-07-07 2020-02-12 Acetylon Pharmaceuticals, Inc. Traitement de la leucémie par des inhibiteurs des histone désacétylases
CA2969790A1 (fr) 2014-12-05 2016-06-09 University of Modena and Reggio Emilia Combinaisons d'inhibiteurs d'histone deacetylase et de bendamustine
US10272084B2 (en) 2015-06-01 2019-04-30 Regenacy Pharmaceuticals, Llc Histone deacetylase 6 selective inhibitors for the treatment of cisplatin-induced peripheral neuropathy
JP2019515909A (ja) 2016-04-19 2019-06-13 アセチロン ファーマシューティカルズ インコーポレイテッドＡｃｅｔｙｌｏｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ，Ｉｎｃ． 慢性リンパ性白血病の治療を目的とするｈｄａｃ阻害剤単独またはｂｔｋ阻害剤との配合物

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002074753A2 (fr) * 2001-03-15 2002-09-26 Basf Aktiengesellschaft 5-phenylpyrimidines, procede et produits intermediaires utilises pour les produire et leur utilisation pour lutter contre des champignons nuisibles
WO2003043993A1 (fr) * 2001-11-19 2003-05-30 Basf Aktiengesellschaft 5-phenylpyrimidines, procede pour les produire, agents les contenant et leur utilisation

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU778913B2 (en) 2000-06-13 2004-12-23 Basf Aktiengesellschaft Fungicidal 5-phenyl substituted 2-(cyanoamino) pyrimidines

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002074753A2 (fr) * 2001-03-15 2002-09-26 Basf Aktiengesellschaft 5-phenylpyrimidines, procede et produits intermediaires utilises pour les produire et leur utilisation pour lutter contre des champignons nuisibles
WO2003043993A1 (fr) * 2001-11-19 2003-05-30 Basf Aktiengesellschaft 5-phenylpyrimidines, procede pour les produire, agents les contenant et leur utilisation

Also Published As

Publication number Publication date
NZ545103A (en) 2008-06-30
US20070105873A1 (en) 2007-05-10
MXPA06000038A (es) 2006-03-21
PL1651618T3 (pl) 2007-05-31
ATE350370T1 (de) 2007-01-15
AP2006003497A0 (en) 2006-02-28
UY28436A1 (es) 2005-02-28
CR8184A (es) 2006-10-06
PT1651618E (pt) 2007-03-30
TW200516075A (en) 2005-05-16
JP2006528603A (ja) 2006-12-21
AU2004261373B8 (en) 2010-11-04
SI1651618T1 (sl) 2007-06-30
EP1651618A1 (fr) 2006-05-03
CO5660292A2 (es) 2006-07-31
IL172848A0 (en) 2006-06-11
KR20060052857A (ko) 2006-05-19
ECSP066278A (es) 2006-07-28
PE20050882A1 (es) 2005-12-01
CA2532718A1 (fr) 2005-02-10
EP1651618B1 (fr) 2007-01-03
US7375108B2 (en) 2008-05-20
CY1106391T1 (el) 2011-10-12
ES2279395T3 (es) 2007-08-16
HRP20070057T3 (en) 2007-07-31
AU2004261373A1 (en) 2005-02-10
MA27949A1 (fr) 2006-06-01
AR045100A1 (es) 2005-10-12
WO2005012261A1 (fr) 2005-02-10
BRPI0412891A (pt) 2006-10-03
DK1651618T3 (da) 2007-05-14
EA200600212A1 (ru) 2006-08-25
DE502004002570D1 (de) 2007-02-15
AU2004261373B2 (en) 2010-08-19
EA010566B1 (ru) 2008-10-30

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