AP2157A - 2-substituted pyrimidines. - Google Patents
2-substituted pyrimidines.Info
- Publication number
- AP2157A AP2157A AP2006003497A AP2006003497A AP2157A AP 2157 A AP2157 A AP 2157A AP 2006003497 A AP2006003497 A AP 2006003497A AP 2006003497 A AP2006003497 A AP 2006003497A AP 2157 A AP2157 A AP 2157A
- Authority
- AP
- ARIPO
- Prior art keywords
- substituted pyrimidines
- pyrimidines
- substituted
- Prior art date
Links
- -1 2-substituted pyrimidines Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/42—One nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/30—Halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10333857 | 2003-07-24 | ||
| DE10357714 | 2003-12-09 | ||
| PCT/EP2004/007877 WO2005012261A1 (de) | 2003-07-24 | 2004-07-15 | 2-substituierte pyrimidine |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AP2006003497A0 AP2006003497A0 (en) | 2006-02-28 |
| AP2157A true AP2157A (en) | 2010-09-13 |
Family
ID=34117367
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AP2006003497A AP2157A (en) | 2003-07-24 | 2004-07-15 | 2-substituted pyrimidines. |
Country Status (30)
| Country | Link |
|---|---|
| US (1) | US7375108B2 (da) |
| EP (1) | EP1651618B1 (da) |
| JP (1) | JP2006528603A (da) |
| KR (1) | KR20060052857A (da) |
| AP (1) | AP2157A (da) |
| AR (1) | AR045100A1 (da) |
| AT (1) | ATE350370T1 (da) |
| AU (1) | AU2004261373B8 (da) |
| BR (1) | BRPI0412891A (da) |
| CA (1) | CA2532718A1 (da) |
| CO (1) | CO5660292A2 (da) |
| CR (1) | CR8184A (da) |
| CY (1) | CY1106391T1 (da) |
| DE (1) | DE502004002570D1 (da) |
| DK (1) | DK1651618T3 (da) |
| EA (1) | EA010566B1 (da) |
| EC (1) | ECSP066278A (da) |
| ES (1) | ES2279395T3 (da) |
| HR (1) | HRP20070057T3 (da) |
| IL (1) | IL172848A0 (da) |
| MA (1) | MA27949A1 (da) |
| MX (1) | MXPA06000038A (da) |
| NZ (1) | NZ545103A (da) |
| PE (1) | PE20050882A1 (da) |
| PL (1) | PL1651618T3 (da) |
| PT (1) | PT1651618E (da) |
| SI (1) | SI1651618T1 (da) |
| TW (1) | TW200516075A (da) |
| UY (1) | UY28436A1 (da) |
| WO (1) | WO2005012261A1 (da) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20080132522A1 (en) * | 2004-07-14 | 2008-06-05 | Basf Aktiengesellschaft | 2-Substituted Pyrimidines, Method for Their Production and Their Use for Controlling Pathogenic Fungi |
| CL2007002231A1 (es) * | 2006-08-02 | 2008-04-11 | Basf Ag | Uso de compuestos derivados de 5-(het) arilpirimidina para combatir hongos daninos; compuestos derivados de 5-(het) arilpirimidina; agente fungicida; y agente farmaceutico. |
| JP6041808B2 (ja) * | 2010-11-16 | 2016-12-14 | アセチロン ファーマシューティカルズ インコーポレイテッドＡｃｅｔｙｌｏｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ，Ｉｎｃ． | 蛋白質脱アセチル化酵素抑制剤としてのピリミジン水酸基アミド化合物およびその利用方法 |
| US9403779B2 (en) | 2013-10-08 | 2016-08-02 | Acetylon Pharmaceuticals, Inc. | Combinations of histone deacetylase inhibitors and either Her2 inhibitors or PI3K inhibitors |
| EP3055299B1 (en) | 2013-10-10 | 2021-01-06 | Acetylon Pharmaceuticals, Inc. | Pyrimidine hydroxy amide compounds as histone deacetylase inhibitors |
| JP2016534069A (ja) | 2013-10-24 | 2016-11-04 | メイヨ・ファウンデーション・フォー・メディカル・エデュケーション・アンド・リサーチ | Ｈｄａｃ６阻害剤での多嚢胞性疾患の治療 |
| US9949972B2 (en) | 2013-12-03 | 2018-04-24 | Acetylon Pharmaceuticals, Inc | Combinations of histone deacetylase inhibitors and immunomodulatory drugs |
| US9464073B2 (en) | 2014-02-26 | 2016-10-11 | Acetylon Pharmaceuticals, Inc. | Pyrimidine hydroxy amide compounds as HDAC6 selective inhibitors |
| EP3166603B1 (en) | 2014-07-07 | 2020-02-12 | Acetylon Pharmaceuticals, Inc. | Treatment of leukemia with histone deacetylase inhibitors |
| CA2969790A1 (en) | 2014-12-05 | 2016-06-09 | University of Modena and Reggio Emilia | Combinations of histone deacetylase inhibitors and bendamustine |
| US10272084B2 (en) | 2015-06-01 | 2019-04-30 | Regenacy Pharmaceuticals, Llc | Histone deacetylase 6 selective inhibitors for the treatment of cisplatin-induced peripheral neuropathy |
| JP2019515909A (ja) | 2016-04-19 | 2019-06-13 | アセチロン ファーマシューティカルズ インコーポレイテッドＡｃｅｔｙｌｏｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ，Ｉｎｃ． | 慢性リンパ性白血病の治療を目的とするｈｄａｃ阻害剤単独またはｂｔｋ阻害剤との配合物 |
| US20210369664A1 (en) * | 2016-07-20 | 2021-12-02 | Tohoku University | Prophylactic or therapeutic agent for pulmonary hypertension which comprises ppar? agonist |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002074753A2 (de) * | 2001-03-15 | 2002-09-26 | Basf Aktiengesellschaft | 5-phenylpyrimidine, verfahren und zwischenprodukte zu ihrer herstellung und ihre verwendung zur bekaempfung von schadpilzen |
| WO2003043993A1 (de) * | 2001-11-19 | 2003-05-30 | Basf Aktiengesellschaft | 5-phenylpyrimidine, verfahren zu ihrer herstellung, sie enthaltende mittel und ihre verwendung |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2412010A1 (en) | 2000-06-13 | 2001-12-20 | Basf Aktiengesellschaft | Fungicidal 5-phenyl substituted 2-(cyanoamino) pyrimidines |
-
2004
- 2004-07-15 AU AU2004261373A patent/AU2004261373B8/en not_active Ceased
- 2004-07-15 ES ES04741053T patent/ES2279395T3/es not_active Expired - Lifetime
- 2004-07-15 SI SI200430228T patent/SI1651618T1/sl unknown
- 2004-07-15 HR HR20070057T patent/HRP20070057T3/xx unknown
- 2004-07-15 DK DK04741053T patent/DK1651618T3/da active
- 2004-07-15 MX MXPA06000038A patent/MXPA06000038A/es active IP Right Grant
- 2004-07-15 CA CA002532718A patent/CA2532718A1/en not_active Abandoned
- 2004-07-15 EA EA200600212A patent/EA010566B1/ru not_active IP Right Cessation
- 2004-07-15 JP JP2006520743A patent/JP2006528603A/ja active Pending
- 2004-07-15 DE DE502004002570T patent/DE502004002570D1/de not_active Expired - Lifetime
- 2004-07-15 EP EP04741053A patent/EP1651618B1/de not_active Expired - Lifetime
- 2004-07-15 BR BRPI0412891-5A patent/BRPI0412891A/pt not_active IP Right Cessation
- 2004-07-15 US US10/564,013 patent/US7375108B2/en not_active Expired - Fee Related
- 2004-07-15 AT AT04741053T patent/ATE350370T1/de not_active IP Right Cessation
- 2004-07-15 PL PL04741053T patent/PL1651618T3/pl unknown
- 2004-07-15 NZ NZ545103A patent/NZ545103A/en unknown
- 2004-07-15 PT PT04741053T patent/PT1651618E/pt unknown
- 2004-07-15 WO PCT/EP2004/007877 patent/WO2005012261A1/de not_active Ceased
- 2004-07-15 AP AP2006003497A patent/AP2157A/xx active
- 2004-07-15 KR KR1020067001493A patent/KR20060052857A/ko not_active Ceased
- 2004-07-22 PE PE2004000707A patent/PE20050882A1/es not_active Application Discontinuation
- 2004-07-23 TW TW093122163A patent/TW200516075A/zh unknown
- 2004-07-23 UY UY28436A patent/UY28436A1/es unknown
- 2004-07-23 AR ARP040102631A patent/AR045100A1/es active IP Right Grant
-
2005
- 2005-12-27 IL IL172848A patent/IL172848A0/en not_active IP Right Cessation
-
2006
- 2006-01-11 CR CR8184A patent/CR8184A/es unknown
- 2006-01-11 EC EC2006006278A patent/ECSP066278A/es unknown
- 2006-01-24 CO CO06006393A patent/CO5660292A2/es not_active Application Discontinuation
- 2006-02-15 MA MA28806A patent/MA27949A1/fr unknown
-
2007
- 2007-03-16 CY CY20071100372T patent/CY1106391T1/el unknown
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002074753A2 (de) * | 2001-03-15 | 2002-09-26 | Basf Aktiengesellschaft | 5-phenylpyrimidine, verfahren und zwischenprodukte zu ihrer herstellung und ihre verwendung zur bekaempfung von schadpilzen |
| WO2003043993A1 (de) * | 2001-11-19 | 2003-05-30 | Basf Aktiengesellschaft | 5-phenylpyrimidine, verfahren zu ihrer herstellung, sie enthaltende mittel und ihre verwendung |
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