AP2109A - Combinations of a pyrimidine containing NNRTI withRT inhibitors - Google Patents

Combinations of a pyrimidine containing NNRTI withRT inhibitors

Info

Publication number
AP2109A
AP2109A AP2006003551A AP2006003551A AP2109A AP 2109 A AP2109 A AP 2109A AP 2006003551 A AP2006003551 A AP 2006003551A AP 2006003551 A AP2006003551 A AP 2006003551A AP 2109 A AP2109 A AP 2109A
Authority
AP
ARIPO
Prior art keywords
withrt
inhibitors
combinations
pyrimidine containing
nnrti
Prior art date
Application number
AP2006003551A
Other languages
English (en)
Other versions
AP2006003551A0 (en
Inventor
Paul Stoffels
Original Assignee
Tibotec Pharm Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34280181&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AP2109(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Tibotec Pharm Ltd filed Critical Tibotec Pharm Ltd
Publication of AP2006003551A0 publication Critical patent/AP2006003551A0/xx
Application granted granted Critical
Publication of AP2109A publication Critical patent/AP2109A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
AP2006003551A 2003-09-03 2004-09-03 Combinations of a pyrimidine containing NNRTI withRT inhibitors AP2109A (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US49977103P 2003-09-03 2003-09-03
EP03103275 2003-09-03
EP03103319 2003-09-08
EP03103335 2003-09-10
EP03103668 2003-10-02
US50848603P 2003-10-03 2003-10-03
PCT/EP2004/052028 WO2005021001A1 (en) 2003-09-03 2004-09-03 Combinations of a pyrimidine containing nnrti with rt inhibitors

Publications (2)

Publication Number Publication Date
AP2006003551A0 AP2006003551A0 (en) 2006-04-30
AP2109A true AP2109A (en) 2010-02-26

Family

ID=34280181

Family Applications (1)

Application Number Title Priority Date Filing Date
AP2006003551A AP2109A (en) 2003-09-03 2004-09-03 Combinations of a pyrimidine containing NNRTI withRT inhibitors

Country Status (24)

Country Link
US (9) US20080200435A1 (enExample)
EP (1) EP1663240B2 (enExample)
JP (3) JP5507791B2 (enExample)
KR (1) KR20060090658A (enExample)
CN (1) CN101060844B (enExample)
AP (1) AP2109A (enExample)
AU (5) AU2004268390B2 (enExample)
BE (1) BE2015C053I2 (enExample)
CA (1) CA2537095C (enExample)
CY (5) CY2015038I1 (enExample)
FI (1) FI1663240T4 (enExample)
FR (5) FR15C0073I2 (enExample)
HR (1) HRP20150798T4 (enExample)
HU (5) HUS1500054I1 (enExample)
IL (2) IL173438A (enExample)
LT (2) LTPA2016045I1 (enExample)
LU (3) LU92853I2 (enExample)
MX (1) MXPA06002437A (enExample)
MY (1) MY169670A (enExample)
NL (2) NL300781I2 (enExample)
NO (6) NO334877B1 (enExample)
NZ (1) NZ545306A (enExample)
PL (1) PL1663240T5 (enExample)
WO (1) WO2005021001A1 (enExample)

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US8101629B2 (en) 2001-08-13 2012-01-24 Janssen Pharmaceutica N.V. Salt of 4-[[4-[[4-(2-cyanoethenyl)-2,6-dimethylphenyl]amino]-2-pyrimidinyl]amino]benzonitrile
MY169670A (en) 2003-09-03 2019-05-08 Tibotec Pharm Ltd Combinations of a pyrimidine containing nnrti with rt inhibitors
PL208533B1 (pl) 2002-08-09 2011-05-31 Janssen Pharmaceutica Nv Sposób otrzymywania 4-[[4-[[4-(2-cyjanoetenylo)-2,6-dimetylofenylo]amino]-2-pirymidynylo]amino]benzonitrylu oraz sposób otrzymywania związku pośredniego
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Also Published As

Publication number Publication date
CN101060844B (zh) 2012-01-04
FR15C0072I2 (fr) 2019-05-17
AU2011201123B2 (en) 2013-10-10
HUS1500054I1 (hu) 2016-03-29
FI1663240T4 (fi) 2023-04-25
US20140349971A1 (en) 2014-11-27
EP1663240B1 (en) 2015-04-22
NO2014031I1 (no) 2015-01-05
NL300768I1 (enExample) 2015-12-16
JP2007520443A (ja) 2007-07-26
US20200171027A1 (en) 2020-06-04
JP2012051915A (ja) 2012-03-15
FR15C0073I1 (enExample) 2015-04-12
NO20061374L (no) 2006-03-27
HUS1600059I1 (hu) 2017-02-28
NO2014031I2 (no) 2014-12-18
AU2016210733B2 (en) 2018-11-08
US20220008417A1 (en) 2022-01-13
JP5820045B2 (ja) 2015-11-24
NO2014030I1 (no) 2015-01-05
AP2006003551A0 (en) 2006-04-30
NO2014032I2 (no) 2014-12-18
CY2015040I2 (el) 2016-08-31
NZ545306A (en) 2009-11-27
FR16C1024I1 (fr) 2017-02-03
NL300768I2 (nl) 2023-08-09
US20180228800A1 (en) 2018-08-16
HRP20150798T1 (hr) 2015-09-11
CY2015039I2 (el) 2016-08-31
US8841310B2 (en) 2014-09-23
CY2015039I1 (el) 2016-08-31
AU2019200813A1 (en) 2019-02-28
EP1663240B2 (en) 2023-03-01
NO2016025I1 (enExample) 2016-12-20
AU2014203484A1 (en) 2014-07-17
CA2537095C (en) 2012-05-29
AU2004268390A1 (en) 2005-03-10
MXPA06002437A (es) 2006-06-20
FR16C1022I1 (fr) 2017-02-03
FR15C0071I2 (fr) 2016-02-12
NL300781I1 (enExample) 2016-04-19
CY2015038I2 (el) 2016-08-31
LTC1663240I2 (lt) 2022-05-25
NO2014030I2 (no) 2014-12-18
IL213104A0 (en) 2011-07-31
WO2005021001A1 (en) 2005-03-10
US20150283135A1 (en) 2015-10-08
CY2016049I1 (el) 2017-07-12
AU2011201123A1 (en) 2011-04-07
CA2537095A1 (en) 2005-03-10
AU2014203484B2 (en) 2016-09-29
EP1663240A1 (en) 2006-06-07
CY2015038I1 (el) 2016-08-31
FR15C0071I1 (enExample) 2015-04-12
CY2016048I1 (el) 2017-07-12
NO2014032I1 (no) 2015-01-05
US20170100398A1 (en) 2017-04-13
CY2015040I1 (el) 2016-08-31
US20190216807A1 (en) 2019-07-18
MY169670A (en) 2019-05-08
PL1663240T5 (pl) 2024-02-26
LU92853I2 (fr) 2015-12-21
FR15C0072I1 (enExample) 2015-04-12
NO334877B1 (no) 2014-06-23
LTPA2016045I1 (lt) 2017-01-10
LTPA2016044I1 (lt) 2017-01-10
CY2016049I2 (el) 2017-07-12
HRP20150798T4 (hr) 2023-06-09
JP5507791B2 (ja) 2014-05-28
HUS1600058I1 (hu) 2017-02-28
JP2015044839A (ja) 2015-03-12
CN101060844A (zh) 2007-10-24
IL213104A (en) 2016-02-29
CY2016048I2 (el) 2017-07-12
BE2015C053I2 (enExample) 2023-12-14
LU92854I2 (fr) 2015-12-21
KR20060090658A (ko) 2006-08-14
NO2016026I1 (no) 2016-12-20
FR15C0073I2 (fr) 2016-02-12
AU2016210733A1 (en) 2016-08-25
HUS1500052I1 (hu) 2016-03-29
IL173438A (en) 2012-03-29
HK1092698A1 (en) 2007-02-16
US20100029591A1 (en) 2010-02-04
LU92855I2 (fr) 2015-12-21
NL300781I2 (enExample) 2016-04-19
US20080200435A1 (en) 2008-08-21
HUS1500053I1 (hu) 2016-03-29
AU2004268390B2 (en) 2011-03-31
IL173438A0 (en) 2006-06-11
PL1663240T3 (pl) 2015-10-30

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