AP2015008504A0 - Use of telomerase inhibitors for the treatment of myeloproliferative disorders and myeloprolifarative neoplasms - Google Patents
Use of telomerase inhibitors for the treatment of myeloproliferative disorders and myeloprolifarative neoplasmsInfo
- Publication number
- AP2015008504A0 AP2015008504A0 AP2015008504A AP2015008504A AP2015008504A0 AP 2015008504 A0 AP2015008504 A0 AP 2015008504A0 AP 2015008504 A AP2015008504 A AP 2015008504A AP 2015008504 A AP2015008504 A AP 2015008504A AP 2015008504 A0 AP2015008504 A0 AP 2015008504A0
- Authority
- AP
- ARIPO
- Prior art keywords
- myeloprolifarative
- neoplasms
- treatment
- myeloproliferative disorders
- telomerase inhibitors
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/7125—Nucleic acids or oligonucleotides having modified internucleoside linkage, i.e. other than 3'-5' phosphodiesters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Oncology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Dermatology (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Otolaryngology (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Compounds Of Unknown Constitution (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261734941P | 2012-12-07 | 2012-12-07 | |
| US201361799069P | 2013-03-15 | 2013-03-15 | |
| US13/841,711 US9375485B2 (en) | 2012-12-07 | 2013-03-15 | Use of telomerase inhibitors for the treatment of myeloproliferative disorders and myeloproliferative neoplasms |
| US201361900347P | 2013-11-05 | 2013-11-05 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AP2015008504A0 true AP2015008504A0 (en) | 2015-06-30 |
Family
ID=50883867
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AP2015008504A AP2015008504A0 (en) | 2012-12-07 | 2013-11-15 | Use of telomerase inhibitors for the treatment of myeloproliferative disorders and myeloprolifarative neoplasms |
Country Status (34)
| Country | Link |
|---|---|
| EP (3) | EP3456333B8 (hr) |
| JP (5) | JP6433911B2 (hr) |
| KR (3) | KR20230028590A (hr) |
| CN (2) | CN111617252A (hr) |
| AP (1) | AP2015008504A0 (hr) |
| AU (4) | AU2013356533B2 (hr) |
| BR (1) | BR112015013260A2 (hr) |
| CA (2) | CA2892907C (hr) |
| CL (2) | CL2015001530A1 (hr) |
| CY (2) | CY1122169T1 (hr) |
| DK (3) | DK3646876T3 (hr) |
| EA (1) | EA032973B1 (hr) |
| ES (3) | ES2744790T3 (hr) |
| FI (1) | FI3646876T3 (hr) |
| HK (2) | HK1210940A1 (hr) |
| HR (3) | HRP20240624T1 (hr) |
| HU (3) | HUE045098T2 (hr) |
| IL (2) | IL239266B (hr) |
| LT (3) | LT2928477T (hr) |
| MA (2) | MA45504B1 (hr) |
| ME (1) | ME03538B (hr) |
| MX (3) | MX2015007169A (hr) |
| MY (1) | MY180634A (hr) |
| NZ (1) | NZ708920A (hr) |
| PH (1) | PH12015501282A1 (hr) |
| PL (3) | PL3456333T3 (hr) |
| PT (3) | PT3456333T (hr) |
| RS (2) | RS59363B1 (hr) |
| SG (3) | SG11201504383TA (hr) |
| SI (3) | SI2928477T1 (hr) |
| TN (1) | TN2015000249A1 (hr) |
| UA (3) | UA126015C2 (hr) |
| WO (1) | WO2014088785A1 (hr) |
| ZA (2) | ZA201504124B (hr) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7485717B2 (en) | 2004-07-02 | 2009-02-03 | Geron Corporation | Synthesis of protected 3′-amino nucleoside monomers |
| CA2929809C (en) | 2013-11-06 | 2022-05-17 | Ayalew Tefferi | Methods and materials for treating hematological malignancies |
| AU2016250576C1 (en) * | 2015-04-23 | 2021-05-06 | Geron Corporation | Methods of polynucleotide preparation using multivalent cation salt compositions |
| EP3318276A1 (en) * | 2016-11-04 | 2018-05-09 | Janssen Biotech, Inc. | Combinations of a telomerase inhibitor and a bcl-2 inhibitor for the treatment of hematological cancers |
| EP3658156A1 (en) | 2017-07-28 | 2020-06-03 | Geron Corporation | Methods of treating myelodysplastic syndrome |
| TWI741286B (zh) * | 2018-04-30 | 2021-10-01 | 美商卡托斯醫療公司 | 治療癌症之方法 |
| JP7401518B2 (ja) * | 2018-07-31 | 2023-12-19 | ジェロン・コーポレーション | テロメラーゼ阻害剤による治療から利益を得る可能性が高い患者を特定する方法 |
| MX2022005354A (es) * | 2019-11-04 | 2022-10-21 | Geron Corp | Uso de un inhibidor de la cinasa janus y un inhibidor de la telomerasa para el tratamiento de neoplasias mieloproliferativas. |
| JP2021157248A (ja) * | 2020-03-25 | 2021-10-07 | パイオニア株式会社 | 状況出力装置 |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5489508A (en) | 1992-05-13 | 1996-02-06 | University Of Texas System Board Of Regents | Therapy and diagnosis of conditions related to telomere length and/or telomerase activity |
| US5958680A (en) | 1994-07-07 | 1999-09-28 | Geron Corporation | Mammalian telomerase |
| US5583016A (en) | 1994-07-07 | 1996-12-10 | Geron Corporation | Mammalian telomerase |
| US5863936A (en) | 1995-04-18 | 1999-01-26 | Geron Corporation | Telomerase inhibitors |
| US5656638A (en) | 1995-04-18 | 1997-08-12 | Geron Corporation | Telomerase inhibitors |
| US5760062A (en) | 1995-04-18 | 1998-06-02 | Geron Corporation | Telomerase inhibitors |
| US5770613A (en) | 1995-09-29 | 1998-06-23 | Geron Corporation | Telomerase inhibitors |
| US5767278A (en) | 1995-10-06 | 1998-06-16 | Geron Corporation | Telomerase inhibitors |
| US6444650B1 (en) | 1996-10-01 | 2002-09-03 | Geron Corporation | Antisense compositions for detecting and inhibiting telomerase reverse transcriptase |
| US6261836B1 (en) | 1996-10-01 | 2001-07-17 | Geron Corporation | Telomerase |
| CA2274586A1 (en) | 1996-12-20 | 1998-07-02 | Geron Corporation | Methods for detecting and inhibiting the rna component of telomerase |
| US6331399B1 (en) | 2000-05-16 | 2001-12-18 | Isis Pharmaceuticals, Inc. | Antisense inhibition of tert expression |
| JP2007525414A (ja) * | 2003-01-31 | 2007-09-06 | ジェシー エル エス オウ | スラミン、ペントサン・ポリサルフェート、テロメラーゼアンチセンス、及びテロメラーゼ阻害剤を用いるための方法及び成分 |
| CN1244592C (zh) * | 2003-07-11 | 2006-03-08 | 暨南大学 | 抑制白血病细胞端粒酶活性的反义核酸及其应用 |
| KR101319388B1 (ko) | 2003-09-09 | 2013-10-22 | 제론 코포레이션 | 텔로머라제 억제를 위한 변형 올리고뉴클레오티드 |
| US20050282893A1 (en) * | 2004-01-30 | 2005-12-22 | Au Jessie L | Methods and compositions for using suramin, pentosan, polysulfate, telomerase antisense and telomerase inhibitors |
| US7485717B2 (en) | 2004-07-02 | 2009-02-03 | Geron Corporation | Synthesis of protected 3′-amino nucleoside monomers |
| FR2877013A1 (fr) | 2004-10-27 | 2006-04-28 | Assist Publ Hopitaux De Paris | Indentification d'une mutation de jak2 impliquee dans la polyglobulie de vaquez |
| US20060166221A1 (en) | 2005-01-21 | 2006-07-27 | Bahou Wadie F | Methods of diagnosing essential thrombocythemia |
| WO2006113426A2 (en) * | 2005-04-15 | 2006-10-26 | Geron Corporation | Cancer treatment by combined inhibition of telomerase and tubulin activities |
| EP1876893B1 (en) | 2005-04-15 | 2012-04-11 | Geron Corporation | Cancer treatment by combined inhibition of proteasome and telomerase activities |
| US20070224598A1 (en) | 2006-03-15 | 2007-09-27 | The Methodist Hospital Research Institute | System and method for detection of mutations in JAK2 polynucleotides |
| US20080021013A1 (en) | 2006-07-21 | 2008-01-24 | Cephalon, Inc. | JAK inhibitors for treatment of myeloproliferative disorders |
| PL2898887T3 (pl) | 2006-10-30 | 2019-05-31 | Geron Corp | Inhibitor telomerazy skojarzony z gemcytabiną do leczenia nowotworu |
| CN101220044B (zh) * | 2008-01-21 | 2010-06-02 | 中国药科大学 | 端粒酶抑制剂及其制备方法和用途 |
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2013
- 2013-11-15 CA CA2892907A patent/CA2892907C/en active Active
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- 2013-11-15 FI FIEP19187756.2T patent/FI3646876T3/fi active
- 2013-11-15 MY MYPI2015001459A patent/MY180634A/en unknown
- 2013-11-15 CA CA3188494A patent/CA3188494A1/en active Pending
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- 2013-11-15 KR KR1020237005641A patent/KR20230028590A/ko not_active Application Discontinuation
- 2013-11-15 MA MA45504A patent/MA45504B1/fr unknown
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- 2013-11-15 PL PL13861008T patent/PL2928477T3/pl unknown
- 2013-11-15 AP AP2015008504A patent/AP2015008504A0/xx unknown
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- 2013-11-15 EP EP19187756.2A patent/EP3646876B1/en active Active
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- 2013-11-15 UA UAA201800703A patent/UA126015C2/uk unknown
- 2013-11-15 UA UAA202100419A patent/UA128370C2/uk unknown
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- 2013-11-15 HU HUE18196690A patent/HUE049858T2/hu unknown
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- 2013-11-15 SG SG10202103341SA patent/SG10202103341SA/en unknown
- 2013-11-15 PT PT138610084T patent/PT2928477T/pt unknown
- 2013-11-15 EP EP13861008.4A patent/EP2928477B1/en active Active
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- 2013-11-15 CN CN201380069553.6A patent/CN104936602B/zh active Active
- 2013-11-15 UA UAA201505480A patent/UA117116C2/uk unknown
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- 2013-11-15 HU HUE19187756A patent/HUE066402T2/hu unknown
- 2013-11-15 DK DK18196690.4T patent/DK3456333T3/da active
- 2013-11-15 WO PCT/US2013/070437 patent/WO2014088785A1/en active Application Filing
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2015
- 2015-06-04 CL CL2015001530A patent/CL2015001530A1/es unknown
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- 2015-06-05 MX MX2022015437A patent/MX2022015437A/es unknown
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- 2015-06-07 IL IL23926615A patent/IL239266B/en active IP Right Grant
- 2015-06-08 ZA ZA2015/04124A patent/ZA201504124B/en unknown
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2016
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2017
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2018
- 2018-12-20 AU AU2018282364A patent/AU2018282364A1/en not_active Abandoned
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2019
- 2019-10-02 HR HRP20191784TT patent/HRP20191784T1/hr unknown
- 2019-10-14 CY CY20191101076T patent/CY1122169T1/el unknown
- 2019-12-23 JP JP2019231517A patent/JP2020041001A/ja active Pending
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2020
- 2020-06-23 CY CY20201100568T patent/CY1123206T1/el unknown
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2021
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2022
- 2022-01-06 JP JP2022000951A patent/JP7288098B2/ja active Active
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2024
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