AP2005003451A0 - HIV integrase inhibitors. - Google Patents

HIV integrase inhibitors.

Info

Publication number
AP2005003451A0
AP2005003451A0 AP2005003451A AP2005003451A AP2005003451A0 AP 2005003451 A0 AP2005003451 A0 AP 2005003451A0 AP 2005003451 A AP2005003451 A AP 2005003451A AP 2005003451 A AP2005003451 A AP 2005003451A AP 2005003451 A0 AP2005003451 A0 AP 2005003451A0
Authority
AP
ARIPO
Prior art keywords
hiv integrase
integrase inhibitors
inhibitors
hiv
integrase
Prior art date
Application number
AP2005003451A
Other languages
English (en)
Inventor
Wim Gaston Verschueren
Inge Dierynck
Dominique Louis Nest Surleraux
Original Assignee
Tibotec Pharm Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tibotec Pharm Ltd filed Critical Tibotec Pharm Ltd
Publication of AP2005003451A0 publication Critical patent/AP2005003451A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • AIDS & HIV (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Plural Heterocyclic Compounds (AREA)
AP2005003451A 2003-04-28 2004-04-27 HIV integrase inhibitors. AP2005003451A0 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US46598703P 2003-04-28 2003-04-28
EP03101164 2003-04-28
PCT/EP2004/050621 WO2004096807A2 (en) 2003-04-28 2004-04-27 Hiv integrase inhibitors

Publications (1)

Publication Number Publication Date
AP2005003451A0 true AP2005003451A0 (en) 2005-12-31

Family

ID=33420586

Family Applications (1)

Application Number Title Priority Date Filing Date
AP2005003451A AP2005003451A0 (en) 2003-04-28 2004-04-27 HIV integrase inhibitors.

Country Status (13)

Country Link
US (1) US20060211724A1 (es)
EP (1) EP1625130A2 (es)
KR (1) KR20060006047A (es)
CN (1) CN1812992A (es)
AP (1) AP2005003451A0 (es)
AR (1) AR044518A1 (es)
AU (1) AU2004234087A1 (es)
BR (1) BRPI0409873A (es)
CA (1) CA2522990A1 (es)
MX (1) MXPA05011726A (es)
NO (1) NO20055230L (es)
TW (1) TW200507848A (es)
WO (1) WO2004096807A2 (es)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200716632A (en) * 2005-05-16 2007-05-01 Gilead Sciences Inc Integrase inhibitor compounds
AU2006246930C1 (en) 2005-05-19 2012-01-19 Merck Canada Inc. Quinoline derivatives as EP4 antagonists
AR057455A1 (es) 2005-07-22 2007-12-05 Merck & Co Inc Inhibidores de la transcriptasa reversa de vih y composicion farmaceutica
CA2616314A1 (en) * 2005-07-27 2007-02-01 Gilead Sciences, Inc. Antiviral phosphonate conjugates for inhibition of hiv
US20080039487A1 (en) * 2005-12-21 2008-02-14 Gilead Sciences, Llc Processes and intermediates useful for preparing integrase inhibitor compounds
US20090306054A1 (en) 2006-05-16 2009-12-10 Gilead Sciences ,Inc. Integrase inhibitors
EP1916249A1 (en) * 2006-10-10 2008-04-30 LEK Pharmaceuticals D.D. 3-(benzo[d][1,3]dioxol-5-ylmethyl)-4-(thio)oxo-2-(thio)oxo-azolidin-5-ylidene derivatives as antibacterial agents
DK2124562T3 (en) 2007-03-09 2016-08-01 Second Genome Inc BICYCLOHETEROARYLFORBINDELSER AS P2X7 modulators and uses thereof
WO2009067541A2 (en) * 2007-11-20 2009-05-28 Gilead Sciences, Inc. Integrase inhibitors
CN101977610B (zh) 2008-01-25 2012-05-16 奇默里克斯公司 治疗病毒感染的方法
US8822500B2 (en) 2008-03-19 2014-09-02 Chembridge Corporation Tyrosine kinase inhibitors
US9249147B2 (en) 2008-03-19 2016-02-02 Chembridge Corporation Tyrosine kinase inhibitors
AU2009226153B2 (en) 2008-03-19 2014-02-20 Chembridge Corporation Novel tyrosine kinase inhibitors
EP2417140B1 (en) * 2009-04-09 2014-11-26 Boehringer Ingelheim International GmbH Inhibitors of hiv replication
US8283366B2 (en) 2010-01-22 2012-10-09 Ambrilia Biopharma, Inc. Derivatives of pyridoxine for inhibiting HIV integrase
PT2534150T (pt) 2010-02-12 2017-05-02 Chimerix Inc Métodos para tratar uma infecção viral
US10513515B2 (en) 2017-08-25 2019-12-24 Biotheryx, Inc. Ether compounds and uses thereof
CA3106239A1 (en) 2018-07-27 2020-01-30 Biotheryx, Inc. Bifunctional compounds as cdk modulators
US11897930B2 (en) 2020-04-28 2024-02-13 Anwita Biosciences, Inc. Interleukin-2 polypeptides and fusion proteins thereof, and their pharmaceutical compositions and therapeutic applications

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6544732B1 (en) * 1999-05-20 2003-04-08 Illumina, Inc. Encoding and decoding of array sensors utilizing nanocrystals
JP2004517860A (ja) * 2000-10-12 2004-06-17 メルク　エンド　カムパニー　インコーポレーテッド Ｈｉｖインテグラーゼ阻害薬として有用なアザ−およびポリアザ−ナフタレニルカルボキサミド類
WO2004035577A2 (en) * 2002-10-16 2004-04-29 Gilead Sciences, Inc. Pre-organized tricyclic integrase inhibitor compounds
US7442773B2 (en) * 2004-01-23 2008-10-28 The Board Of Trustees Of The University Of Illinois Universal peptide-binding scaffolds and protein chips

Also Published As

Publication number Publication date
WO2004096807A3 (en) 2005-01-06
MXPA05011726A (es) 2006-01-23
CN1812992A (zh) 2006-08-02
KR20060006047A (ko) 2006-01-18
WO2004096807A8 (en) 2005-09-22
CA2522990A1 (en) 2004-11-11
NO20055230L (no) 2005-11-07
EP1625130A2 (en) 2006-02-15
BRPI0409873A (pt) 2006-05-16
AR044518A1 (es) 2005-09-14
TW200507848A (en) 2005-03-01
AU2004234087A1 (en) 2004-11-11
US20060211724A1 (en) 2006-09-21
WO2004096807A2 (en) 2004-11-11

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