WO2009138882A4 - Doppler motion sensor apparatus and method of using same - Google Patents

Doppler motion sensor apparatus and method of using same Download PDF

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Publication number
WO2009138882A4
WO2009138882A4 PCT/IB2009/006082 IB2009006082W WO2009138882A4 WO 2009138882 A4 WO2009138882 A4 WO 2009138882A4 IB 2009006082 W IB2009006082 W IB 2009006082W WO 2009138882 A4 WO2009138882 A4 WO 2009138882A4
Authority
WO
WIPO (PCT)
Prior art keywords
blood
acoustic energy
transducer
sensing device
vessel
Prior art date
Application number
PCT/IB2009/006082
Other languages
French (fr)
Other versions
WO2009138882A3 (en
WO2009138882A2 (en
Inventor
Dan Gur Furman
Original Assignee
Cardio Art Technologies, Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US12/119,462 external-priority patent/US9037208B2/en
Priority claimed from US12/206,885 external-priority patent/US20090048518A1/en
Application filed by Cardio Art Technologies, Ltd. filed Critical Cardio Art Technologies, Ltd.
Priority to CN200980122318.4A priority Critical patent/CN102065773B/en
Priority to JP2011509041A priority patent/JP5405564B2/en
Priority to CA2722659A priority patent/CA2722659A1/en
Priority to EP09746177A priority patent/EP2285288A4/en
Publication of WO2009138882A2 publication Critical patent/WO2009138882A2/en
Publication of WO2009138882A3 publication Critical patent/WO2009138882A3/en
Publication of WO2009138882A4 publication Critical patent/WO2009138882A4/en
Priority to IL209213A priority patent/IL209213A/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A61B5/1459—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters invasive, e.g. introduced into the body by a catheter
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/02007—Evaluating blood vessel condition, e.g. elasticity, compliance
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14542—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring blood gases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/48—Other medical applications
    • A61B5/4887—Locating particular structures in or on the body
    • A61B5/489—Blood vessels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/04—Measuring blood pressure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/06—Measuring blood flow
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/12—Diagnosis using ultrasonic, sonic or infrasonic waves in body cavities or body tracts, e.g. by using catheters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/44—Constructional features of the ultrasonic, sonic or infrasonic diagnostic device
    • A61B8/4483—Constructional features of the ultrasonic, sonic or infrasonic diagnostic device characterised by features of the ultrasound transducer
    • A61B8/4494—Constructional features of the ultrasonic, sonic or infrasonic diagnostic device characterised by features of the ultrasound transducer characterised by the arrangement of the transducer elements

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Vascular Medicine (AREA)
  • Optics & Photonics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Physiology (AREA)
  • Cardiology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
  • Measuring And Recording Apparatus For Diagnosis (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating Or Analyzing Materials By The Use Of Ultrasonic Waves (AREA)
  • Optical Measuring Cells (AREA)

Abstract

An apparatus for, and method of, sensing characteristics of a vessel and a fluid conveyed therein In one embodiment, the sensing device for acquiring signals and computing measurements comprises a sensor Including one or more transducers for transmitting acoustic energy, receiving acoustic energy, and converting the received acoustic'energy into one or more signals, the one or more transducers facing a side of a vessel, a computing device operating the one or more transducers and processing the one or more signals to obtain measurement values, and a housing enclosing the sensor and the computing device

Claims

29AMENDED CLAIMS [Received by the International Bureau on 01 April 2010 (01.04.10)]
1. A sensing device for acquiring signals and computing measurements comprising: a sensor including a first transducer for transmitting acoustic energy, receiving acoustic energy, and converting the received acoustic energy into one or more signals, the first transducer comprising two transducer portions oriented in different directions toward a blood conveying vessel of a mammal such that at least one of the two transducer portions is oriented at an angle of at most about 20 degrees relative to the longitudinal axis of the blood conveying vessel measured where the acoustic energy impinges on the blood conveying vessel; a computing device operating the first transducer and calculating a blood parameter based on the one or more signals; and a housing enclosing the sensor and the computing device, the housing having a vessel facing wall through which the acoustic energy passes and further including attachment features configured Io attach the housing to the mammal in a spaced apart relation with the vessel.
2. The sensing device of claim 1 , further including a second transducer oriented at an angle greater than zero relative to the first transducer.
3. The sensing device of claim 2, wherein the first and the second transducers transmit the acoustic energy through, respectively, a first window and a second window, and where the first window is at least partially surrounded by blocking material that reduces acoustic interference between the first and the second transducers.
4. The sensing device of claim 2, wherein the first transducer and the second transducer transmit acoustic energy at different frequencies.
5. The sensing device of claim 1, wherein the blood parameter comprises blood velocity.
6. The sensing device of claim 5, wherein the sensing device further includes an optical sensor configured to transmit and receive a plurality of optical signals, wherein the computing device calculates the diameter of the blood vessel and a distance between the blood vessel and the vessel facing wall based on the optical signals, and wherein the computing device further calculates blood pressure based on the blood velocity, the diameter, and the distance. 30
7. The sensing device of claim 1 , further including a communication device for transmitting and receiving a communication signal.
8. The sensing device of claim 7, wherein the communication signal includes the distance.
9. The sensing device of claim 8, wherein the computing device further calculates blood pressure based on the blood velocity and the diameter.
10. The sensing device of claim 7, wherein the communication signal includes an alarm.
11. The sensing device of claim 1, wherein the computing device diagnoses a condition using the blood parameter and performs a function in response to the condition.
12. The sensing device of claim 11, wherein the function comprises at least one of communicating an alarm, initiating a treatment, applying an electric shock, delivering a drug, and communicating data with the communication device on a continuous basis.
13. The sensing device of claim 1, wherein the sensing device includes a connector adapted to operably couple to one or more of a docking station, a second sensing device, and an energy source.
14. The sensing device of claim 1, wherein the housing is configured for subcutaneous implantation.
15. The sensing device of claim 1, wherein the sensing device is dimensioned about the same as two stacked quarter dollar coins.
16. The sensing device of claim 1, further including an energy storage device and an energy coupler for receiving energy to recharge the energy storage device.
17. A method for acquiring signals and transmitting data comprising: providing a sensing device including a sensor spaced apart from a vessel, the sensor including one or more transducers for transmitting acoustic energy, receiving acoustic energy, and converting the received acoustic energy into one or more signals, the one or more transducers facing a side of the vessel, at least one of the transducers comprising two transducer portions oriented in different directions such that at least one of the two transducer portions is oriented at an angle of ai most about 20 degrees relative to the longitudinal axis of the vessel measured where the acoustic energy impinges on the vessel; a computing device for operating the one or more transducers and processing the one or more signals to obtain measurement values, and a housing enclosing the sensor and the computing device; transmitting acoustic energy from the one or more transducers; receiving acoustic energy from the one or more transducers to obtain one or more signals; processing the one or more signals to obtain measurement values; analyzing the measurement values to obtain a parameter value indicative of a characteristic of the fluid.
18. The method of claim 17, wherein the fluid is blood and the parameter is one of blood pressure and blood velocity.
19. The method of claim 17, further including the step of obtaining relative position values and storing the relative position values in memory.
20. The method of claim 19, wherein the obtaining step includes receiving relative position values from the communication device and storing the relative position values in memory.
21. The method of claim 18, wherein the sensing device includes an optical sensor, wherein the obtaining step includes receiving relative position information from the optical sensor and converting the relative position information into relative position values.
22. The method of claim 17, further including the steps of diagnosing a condition using the parameter value and performing a function in response to the diagnosing step.
23. The method of claim 28, wherein the function comprises at least one of communicating an alarm, initialing a treatment, applying an electric shock, delivering a drug, and communicating data with the communication device on a continuous basis.
24. The method of claim 17, wherein the receiving step includes sequentially obtaining signals from at least some of the one or more transducers to compute a parameter value.
25. The method of claim 17, wherein each of the one or more transducers comprises a linear array of transducer segments.
26. The method of claim 25, further including the step of selecting one or more transducer segments and preventing transmission and reception of acoustic energy by unsclcctcd transducer segments. 32
27. The method of claim 26, wherein the selecting step includes determining an incidence angle Of acoustic energy relative to the direction of fluid flow and choosing transducer segments when the incidence angle is smaller than, or equal to, 20 degrees.
28. The method of claim 26, wherein the sensing device further includes the optical sensor, and the selecting step includes identifying with the optical sensor any transducer segment where the acoustic energy transmitted by the transducer segment is obstructed and choosing unobstructed transducer segments.
29. A device for acoustically measuring a characteristic of at least one of a blood vessel and blood flowing through the blood vessel of a mammal, the device including: a housing having a first side and a second side; a sensor assembly mounted to the housing and including one or more transducers for transmitting acoustic energy through the first side of the housing, receiving acoustic energy though the first side of the housing, and converting the acoustic energy into signals, the one or more transducers including a first transducer comprising two transducer portions oriented in different directions toward the blood vessel such that one of the two transducer portions is oriented at an angle of at most about 20 degrees relative to the longitudinal axis of the blood vessel measured where the acoustic energy impinges on the blood vessel; and a computing device configured to activate the one or more transducers and interpret the signals to determine the characteristic, wherein the housing encloses the sensor and the computing device, and wherein the housing includes attachment features configured to attach the housing to the mammal in a spaced apart relation with the vessel.
30. The device of claim 29, wherein the sensor assembly comprises acoustic energy blocking material and includes windows for transmitting and receiving acoustic energy.
31. The device of claim 29, wherein the housing is made of acoustic energy blocking material and includes windows for transmitting and receiving acoustic energy.
32. A system for acquiring signals and computing measurements comprising: a cardiac device implanted in a patient; 33
a sensor spaced apart from a blood vessel, the sensor including one or more transducers for transmitting acoustic energy, receiving acoustic energy, and converting the received acoustic energy into one or more signals, the one or more transducers facing a side of the blood vessel, at least one of the transducers comprising two transducer portions oriented in different directions such that at least one of the two transducer portions is oriented at an angle of at most about 20 degrees relative to the longitudinal axis of the blood vessel measured where the acoustic energy impinges on the blood vessel; a computing device operating the one or more transducers and processing the one or more signals to obtain a blood velocity value of blood flowing in-the blood vessel; and a housing enclosing the sensor and the computing device.
33. The system of claim 32, further including a communication device for transmitting and receiving a communication signal based on the one or more signals obtained from the one or more transducers.
34. The system of claim 32, wherein the cardiac device is enclosed within the housing.
35. The system of claim 32, wherein the sensor and the computing device arc operably coupled to the cardiac device which is positioned outside the housing.
36. The sensing device of claim 32, wherein the transducer segments are selectively activated to transmit and to receive acoustic energy.
37. A sensing device configured to measure blood pressure, including: a Doppler sensor having a plurality of transducers for emitting source waves and delecting reflected waves, the Doppler sensor having an associated reference location; an optica) sensor including a plurality of emitters and a plurality of detectors for generating a plurality of signals representing a first distance between the reference location and a near wall of the vessel and a second distance between the reference location and a far wall of the vessel; a computing device configured to, for each of a plurality of pressure calculations, determine the first and second distances to compute an area of the vessel and to determine a segment of a transducer that detects reflected waves from blood 34
flowing through the vessel to thereby determine the velocity of the blood, the velocity and area being used to compute blood pressure; and a housing enclosing the Doppler sensor, the optical sensor, and the computing device.
38. The sensing device of claim 37, wherein the segment of the transducer that detects reflected waves is determined by determining a direction of blood flow and selecting from the plurality of transducers the segment detecting reflected waves having a wave orientation falling within +/- 20 degrees of the direction of blood flow.
39. The sensing device of claim 37, wherein the blood pressure is based on a maximum and a minimum blood velocity calculated from a plurality of blood velocity measurements corresponding to systolic and diastolic pressure, respectively, derived from the reflected waves detected by the segment of the transducer, and a maximum and a minimum diameter of the vessel computed based on first and second distance measurements obtained at times corresponding to the systolic and diastolic pressures.
PCT/IB2009/006082 2008-05-12 2009-05-12 Doppler motion sensor apparatus and method of using same WO2009138882A2 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
CN200980122318.4A CN102065773B (en) 2008-05-12 2009-05-12 Doppler motion sensor apparatus and method of using same
JP2011509041A JP5405564B2 (en) 2008-05-12 2009-05-12 Doppler motion sensor device and method of use thereof
CA2722659A CA2722659A1 (en) 2008-05-12 2009-05-12 Doppler motion sensor apparatus and method of using same
EP09746177A EP2285288A4 (en) 2008-05-12 2009-05-12 Doppler motion sensor apparatus and method of using same
IL209213A IL209213A (en) 2008-05-12 2010-11-09 Doppler motion sensor apparatus

Applications Claiming Priority (10)

Application Number Priority Date Filing Date Title
US12/119,462 US9037208B2 (en) 2005-12-08 2008-05-12 Method and system for monitoring a health condition
US12/119,462 2008-05-12
US12/119,325 US8298148B2 (en) 2005-12-08 2008-05-12 Integrated heart monitoring device and method of using same
US12/119,339 2008-05-12
US12/119,315 US8442606B2 (en) 2006-12-10 2008-05-12 Optical sensor apparatus and method of using same
US12/119,339 US20080287800A1 (en) 2006-12-10 2008-05-12 Doppler motion sensor apparatus and method of using same
US12/119,325 2008-05-12
US12/119,315 2008-05-12
US12/206,885 2008-09-09
US12/206,885 US20090048518A1 (en) 2006-12-10 2008-09-09 Doppler motion sensor apparatus and method of using same

Publications (3)

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WO2009138882A2 WO2009138882A2 (en) 2009-11-19
WO2009138882A3 WO2009138882A3 (en) 2010-04-08
WO2009138882A4 true WO2009138882A4 (en) 2010-05-27

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PCT/IB2009/006088 WO2009138883A2 (en) 2008-05-12 2009-05-12 Integrated heart monitoring device and method of using same
PCT/IB2009/006082 WO2009138882A2 (en) 2008-05-12 2009-05-12 Doppler motion sensor apparatus and method of using same
PCT/IB2009/006081 WO2009138881A2 (en) 2008-05-12 2009-05-12 Method and system for monitoring a health condition
PCT/IB2009/006078 WO2009138880A2 (en) 2008-05-12 2009-05-12 Optical sensor apparatus and method of using same

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PCT/IB2009/006078 WO2009138880A2 (en) 2008-05-12 2009-05-12 Optical sensor apparatus and method of using same

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EP (4) EP2282671A4 (en)
JP (4) JP5650104B2 (en)
CN (4) CN102046085B (en)
CA (4) CA2722662A1 (en)
IL (4) IL209213A (en)
WO (4) WO2009138883A2 (en)

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