US3906092A
(en)
|
1971-11-26 |
1975-09-16 |
Merck & Co Inc |
Stimulation of antibody response
|
US4790987A
(en)
|
1985-11-15 |
1988-12-13 |
Research Corporation |
Viral glycoprotein subunit vaccine
|
CA1335429C
(en)
|
1986-03-07 |
1995-05-02 |
Geoffrey L. Smith |
Processes for the production of hcmv glycoproteins, antibodies thereto and hcmv vaccines, and recombinant vectors therefor
|
NZ224422A
(en)
|
1987-05-05 |
1990-11-27 |
Molecular Eng Ass |
Composition adapted for intranasal immunisation against viral infection comprising a glycoprotein complexed with a lipid
|
EP0413695B1
(en)
|
1988-04-22 |
1994-05-04 |
The Upjohn Company |
Chimeric glycoproteins containing immunogenic segments of human parainfluenza virus type 3.
|
EP0465529B1
(en)
|
1989-03-21 |
1998-04-29 |
Vical, Inc. |
Expression of exogenous polynucleotide sequences in a vertebrate
|
GB9200117D0
(en)
|
1992-01-06 |
1992-02-26 |
Connaught Lab |
Production of recombinant chimeric proteins for vaccine use
|
EP0625049A4
(en)
|
1992-01-23 |
1995-07-12 |
Vical Inc |
EX VIVO GENTRANSFER.
|
IL112820A0
(en)
|
1994-03-07 |
1995-05-26 |
Merck & Co Inc |
Coordinate in vivo gene expression
|
WO1995026204A1
(en)
|
1994-03-25 |
1995-10-05 |
Isis Pharmaceuticals, Inc. |
Immune stimulation by phosphorothioate oligonucleotide analogs
|
WO1995033835A1
(en)
|
1994-06-02 |
1995-12-14 |
Chiron Corporation |
Nucleic acid immunization using a virus-based infection/transfection system
|
US5795587A
(en)
|
1995-01-23 |
1998-08-18 |
University Of Pittsburgh |
Stable lipid-comprising drug delivery complexes and methods for their production
|
US6019980A
(en)
|
1995-06-07 |
2000-02-01 |
Connaught Laboratories Limited |
Nucleic acid respiratory syncytial virus vaccines
|
US6214966B1
(en)
|
1996-09-26 |
2001-04-10 |
Shearwater Corporation |
Soluble, degradable poly(ethylene glycol) derivatives for controllable release of bound molecules into solution
|
EP0855184A1
(en)
|
1997-01-23 |
1998-07-29 |
Grayson B. Dr. Lipford |
Pharmaceutical composition comprising a polynucleotide and an antigen especially for vaccination
|
US7208161B1
(en)
|
1997-05-23 |
2007-04-24 |
The United States Of America, Represented By The Secretary, Department Of Health And Human Services |
Production of attenuated parainfluenza virus vaccines from cloned nucleotide sequences
|
AU7983198A
(en)
|
1997-06-23 |
1999-01-04 |
Ludwig Institute For Cancer Research |
Improved methods for inducing an immune response
|
CA2305785A1
(en)
|
1997-10-07 |
1999-04-15 |
University Of Maryland Biotechnology Institute |
Method for introducing and expressing rna in animal cells
|
WO1999033982A2
(en)
|
1997-12-23 |
1999-07-08 |
Chiron Corporation |
Human genes and gene expression products i
|
US6514948B1
(en)
|
1999-07-02 |
2003-02-04 |
The Regents Of The University Of California |
Method for enhancing an immune response
|
ATE289630T1
(de)
|
1999-09-09 |
2005-03-15 |
Curevac Gmbh |
Transfer von mrnas unter verwendung von polykationischen verbindungen
|
AU7725500A
(en)
|
1999-09-30 |
2001-04-30 |
National Jewish Medical And Research Center |
Method for inhibition of pathogenic microorganisms
|
US7060291B1
(en)
|
1999-11-24 |
2006-06-13 |
Transave, Inc. |
Modular targeted liposomal delivery system
|
US6998115B2
(en)
|
2000-10-10 |
2006-02-14 |
Massachusetts Institute Of Technology |
Biodegradable poly(β-amino esters) and uses thereof
|
US7708915B2
(en)
|
2004-05-06 |
2010-05-04 |
Castor Trevor P |
Polymer microspheres/nanospheres and encapsulating therapeutic proteins therein
|
US20030232061A1
(en)
|
2001-10-18 |
2003-12-18 |
Fouchier Ronaldus Adrianus Maria |
Recombinant parainfluenza virus expression systems and vaccines comprising heterologous antigens derived from metapneumovirus
|
US8927206B2
(en)
|
2001-01-19 |
2015-01-06 |
Vironovative B.V. |
Virus causing respiratory tract illness in susceptible mammals
|
EP1604688B1
(de)
|
2001-06-05 |
2010-02-03 |
CureVac GmbH |
Stabilisierte Tumorantigen-mRNA mit erhöhtem G/C-Gehalt
|
EP1412065A2
(en)
|
2001-07-27 |
2004-04-28 |
President And Fellows Of Harvard College |
Laminar mixing apparatus and methods
|
CA2462593A1
(en)
|
2001-10-03 |
2003-04-10 |
Kam W. Leong |
Compositions for oral gene therapy and methods of using same
|
DE10162480A1
(de)
|
2001-12-19 |
2003-08-07 |
Ingmar Hoerr |
Die Applikation von mRNA für den Einsatz als Therapeutikum gegen Tumorerkrankungen
|
MXPA04008088A
(es)
|
2002-02-21 |
2005-09-30 |
Medimmune Vaccines Inc |
Sistema de expresion del virus de parainfluenza recombinante y vacunas que comprenden antigenos heterologos derivados del metapneumovirus.
|
WO2003092665A2
(en)
|
2002-05-02 |
2003-11-13 |
Massachusetts Eye And Ear Infirmary |
Ocular drug delivery systems and use thereof
|
DE10221836A1
(de)
|
2002-05-16 |
2003-12-04 |
Lohmann Animal Health Gmbh |
Attenuierung von Metapneumovirus
|
DE10229872A1
(de)
|
2002-07-03 |
2004-01-29 |
Curevac Gmbh |
Immunstimulation durch chemisch modifizierte RNA
|
CA2494485A1
(en)
|
2002-07-25 |
2004-02-05 |
Medimmune, Inc. |
Methods of treating and preventing rsv, hmpv, and piv using anti-rsv, anti-hmpv, and anti-piv antibodies
|
WO2004076645A2
(en)
|
2003-02-27 |
2004-09-10 |
University Of Massachusetts |
Compositions and methods for cytomegalovirus treatment
|
KR101187955B1
(ko)
|
2003-04-25 |
2012-10-08 |
비로노바티브 비브이 |
메타뉴모바이러스 유래 이종 항원을 포함하는 재조합파라인플루엔자 바이러스 발현 시스템 및 백신
|
EP2494986A1
(en)
|
2003-04-25 |
2012-09-05 |
MedImmune Vaccines, Inc. |
Metapneumovirus strains and their use in vaccine formulations and as vectors for expression of antigenic sequences and methods for propagating virus
|
WO2005009346A2
(en)
|
2003-06-24 |
2005-02-03 |
Mirus Corporation |
Inhibition of gene function by delivery of polynucleotide-based gene expression inhibitors to mammalian cells in vivo
|
KR100992646B1
(ko)
|
2003-07-09 |
2010-11-05 |
제이에스알 가부시끼가이샤 |
파장판
|
DE10335833A1
(de)
|
2003-08-05 |
2005-03-03 |
Curevac Gmbh |
Transfektion von Blutzellen mit mRNA zur Immunstimulation und Gentherapie
|
WO2005027963A2
(en)
*
|
2003-09-15 |
2005-03-31 |
The United States Of America As Represented By Thesecretary Of Health And Human Services, Nih |
METHODS AND COMPOSITIONS FOR THE GENERATION OF A PROTECTIVE IMMUNE RESPONSE AGAINTS SARS-CoV
|
US8957034B2
(en)
|
2004-01-28 |
2015-02-17 |
Johns Hopkins University |
Drugs and gene carrier particles that rapidly move through mucous barriers
|
CN101084016A
(zh)
|
2004-04-15 |
2007-12-05 |
克艾思马有限公司 |
能够容易穿透生物学障碍的组合物
|
EP1751178A2
(en)
|
2004-06-04 |
2007-02-14 |
Institut Pasteur |
Nucleic acids, polypeptides, methods of expression, and immunogenic compositions associated with sars corona virus spike protein
|
DE102004035227A1
(de)
|
2004-07-21 |
2006-02-16 |
Curevac Gmbh |
mRNA-Gemisch zur Vakzinierung gegen Tumorerkrankungen
|
DE102004042546A1
(de)
|
2004-09-02 |
2006-03-09 |
Curevac Gmbh |
Kombinationstherapie zur Immunstimulation
|
WO2006056027A1
(en)
|
2004-11-29 |
2006-06-01 |
The Council Of The Queensland Institute Of Medical Research |
Human cytomegalovirus immunotherapy
|
US8354476B2
(en)
|
2004-12-10 |
2013-01-15 |
Kala Pharmaceuticals, Inc. |
Functionalized poly(ether-anhydride) block copolymers
|
WO2006071903A2
(en)
|
2004-12-28 |
2006-07-06 |
Ptc Therapeutics, Inc. |
Cell based methods and systems for the identification of rna regulatory sequences and compounds that modulate their functions
|
GB0504436D0
(en)
|
2005-03-03 |
2005-04-06 |
Glaxosmithkline Biolog Sa |
Vaccine
|
EP2290363B1
(en)
|
2005-03-11 |
2014-01-08 |
Firalis SAS |
Biomarkers for cardiovascular side-effects induced by cox-2 inhibitory compounds
|
KR101288729B1
(ko)
|
2005-04-01 |
2013-07-23 |
인터자인 테크놀로지스, 인코포레이티드 |
약물 전달용 중합체성 마이셀
|
WO2006110214A2
(en)
|
2005-04-08 |
2006-10-19 |
Medimmune, Inc. |
Antibodies against mammalian metapneumovirus
|
US8273339B2
(en)
|
2005-04-12 |
2012-09-25 |
Nektar Therapeutics |
Polymer-based compositions and conjugates of antimicrobial agents
|
EP2279758B1
(en)
|
2005-06-16 |
2015-02-25 |
Nektar Therapeutics |
Conjugates having a degradable linkage and polymeric reagents useful in preparing such conjugates
|
ES2735531T3
(es)
|
2005-08-23 |
2019-12-19 |
Univ Pennsylvania |
ARN que contiene nucleósidos modificados y métodos de uso del mismo
|
WO2007038862A1
(en)
*
|
2005-10-03 |
2007-04-12 |
Seneca College Of Applied Arts & Technology |
Nucleic acid immunological composition for human metapneumovirus
|
EP2026839A4
(en)
|
2005-12-14 |
2009-04-01 |
Univ Oklahoma |
RNA VIRUS VACCINE AND METHODS
|
DE102006007433A1
(de)
|
2006-02-17 |
2007-08-23 |
Curevac Gmbh |
Adjuvanz in Form einer Lipid-modifizierten Nukleinsäure
|
CN103030801B
(zh)
|
2006-02-21 |
2015-07-22 |
尼克塔治疗公司 |
嵌段可降解聚合物及由其制备的轭合物
|
CN101415405A
(zh)
|
2006-04-04 |
2009-04-22 |
Stc.Unm公司 |
用于药物递送的可溶胀颗粒
|
FR2899902B1
(fr)
|
2006-04-18 |
2012-01-27 |
Agronomique Inst Nat Rech |
Proteines de fusion proteine n d'un virus de la famille des paramyxoviridae-proteine d'interet et leurs utilisations pour la vaccination et la vectorisation intra-cellulaire.
|
CN101573141B
(zh)
|
2006-05-15 |
2016-05-04 |
麻省理工学院 |
用于功能性颗粒的聚合物
|
AU2007280690C1
(en)
|
2006-07-31 |
2012-08-23 |
Curevac Gmbh |
Nucleic acid of formula (I): GIXmGn, or (II): CIXmCn, in particular as an immune-stimulating agent/adjuvant
|
US20100215580A1
(en)
|
2006-09-08 |
2010-08-26 |
The Johns Hopkins University |
Compositions and methods for enhancing transport through mucus
|
US20110135645A1
(en)
|
2006-10-04 |
2011-06-09 |
The Scripps Research Institute |
Human antibodies neutralizing human metapneumovirus
|
MX2009003680A
(es)
|
2006-10-05 |
2009-07-17 |
Univ Johns Hopkins |
Formulaciones orales, parenterales y topicas dispersables en agua para farmacos deficientemente solubles en agua con el uso de nanoparticulas polimericas inteligentes.
|
DE102006051516A1
(de)
|
2006-10-31 |
2008-05-08 |
Curevac Gmbh |
(Basen-)modifizierte RNA zur Expressionssteigerung eines Proteins
|
US8399007B2
(en)
|
2006-12-05 |
2013-03-19 |
Landec Corporation |
Method for formulating a controlled-release pharmaceutical formulation
|
EP2120859B1
(en)
|
2006-12-21 |
2013-11-20 |
Stryker Corporation |
Sustained-release formulations comprising bmp-7 crystals
|
DE102007001370A1
(de)
|
2007-01-09 |
2008-07-10 |
Curevac Gmbh |
RNA-kodierte Antikörper
|
WO2009030254A1
(en)
|
2007-09-04 |
2009-03-12 |
Curevac Gmbh |
Complexes of rna and cationic peptides for transfection and for immunostimulation
|
US20090162395A1
(en)
|
2007-09-26 |
2009-06-25 |
Crowe Jr James E |
Vaccine for rsv and mpv
|
HUE034775T2
(hu)
|
2007-09-28 |
2018-02-28 |
Pfizer |
Rákos sejt célzása nanorészecskék alkalmazásával
|
WO2009046738A1
(en)
|
2007-10-09 |
2009-04-16 |
Curevac Gmbh |
Composition for treating lung cancer, particularly of non-small lung cancers (nsclc)
|
WO2009046739A1
(en)
|
2007-10-09 |
2009-04-16 |
Curevac Gmbh |
Composition for treating prostate cancer (pca)
|
KR101483715B1
(ko)
|
2008-01-31 |
2015-01-19 |
큐어백 게엠바하 |
면역증강제/애주번트인 화학식(NuGlXmGnNv)a를 포함하는 핵산 및 이의 유도체
|
WO2009127230A1
(en)
|
2008-04-16 |
2009-10-22 |
Curevac Gmbh |
MODIFIED (m)RNA FOR SUPPRESSING OR AVOIDING AN IMMUNOSTIMULATORY RESPONSE AND IMMUNOSUPPRESSIVE COMPOSITION
|
US8613951B2
(en)
|
2008-06-16 |
2013-12-24 |
Bind Therapeutics, Inc. |
Therapeutic polymeric nanoparticles with mTor inhibitors and methods of making and using same
|
EA020753B1
(ru)
|
2008-06-16 |
2015-01-30 |
Бинд Терапьютикс, Инк. |
Терапевтические полимерные наночастицы, содержащие алкалоиды vinca, и их применение
|
WO2010005740A2
(en)
|
2008-06-16 |
2010-01-14 |
Bind Biosciences, Inc. |
Methods for the preparation of targeting agent functionalized diblock copolymers for use in fabrication of therapeutic targeted nanoparticles
|
JP2012501965A
(ja)
|
2008-06-16 |
2012-01-26 |
バインド バイオサイエンシズ インコーポレイテッド |
薬剤を装填したポリマーナノ粒子及びその製造方法と使用方法
|
WO2010030763A2
(en)
|
2008-09-10 |
2010-03-18 |
Bind Biosciences, Inc. |
High throughput fabrication of nanoparticles
|
WO2010037408A1
(en)
|
2008-09-30 |
2010-04-08 |
Curevac Gmbh |
Composition comprising a complexed (m)rna and a naked mrna for providing or enhancing an immunostimulatory response in a mammal and uses thereof
|
CA2984026C
(en)
|
2008-10-09 |
2020-02-11 |
Arbutus Biopharma Corporation |
Improved amino lipids and methods for the delivery of nucleic acids
|
AU2015210364B2
(en)
|
2008-10-09 |
2017-03-09 |
Arbutus Biopharma Corporation |
Improved amino lipids and methods for the delivery of nucleic acids
|
MX359674B
(es)
|
2008-11-10 |
2018-10-05 |
Alnylam Pharmaceuticals Inc |
Lipidos y composiciones novedosas para el suministro de terapeuticos.
|
US8734853B2
(en)
|
2008-11-17 |
2014-05-27 |
University Of North Texas Health Science Center At Fort Worth |
HDL particles for delivery of nucleic acids
|
JP2012512175A
(ja)
|
2008-12-15 |
2012-05-31 |
バインド バイオサイエンシズ インコーポレイテッド |
治療薬を徐放するための長時間循環性ナノ粒子
|
AU2010208035B2
(en)
|
2009-01-29 |
2016-06-23 |
Arbutus Biopharma Corporation |
Improved lipid formulation for the delivery of nucleic acids
|
WO2010088927A1
(en)
|
2009-02-09 |
2010-08-12 |
Curevac Gmbh |
Use of pei for the improvement of endosomal release and expression of transfected nucleic acids, complexed with cationic or polycationic compounds
|
CN103200961B
(zh)
|
2009-03-27 |
2017-10-27 |
中央研究院 |
抗病毒免疫的方法和组合物
|
JP5622254B2
(ja)
|
2009-03-31 |
2014-11-12 |
国立大学法人東京大学 |
二本鎖リボ核酸ポリイオンコンプレックス
|
KR20120022984A
(ko)
|
2009-04-21 |
2012-03-12 |
셀렉타 바이오사이언시즈, 인크. |
Th1 편향 반응을 제공하는 면역나노치료법
|
US8460680B2
(en)
*
|
2009-04-24 |
2013-06-11 |
National Health Research Institutes |
Polyvalent chimeric rubella virus-based vaccines
|
WO2010127159A2
(en)
|
2009-04-30 |
2010-11-04 |
Intezyne Technologies, Incorporated |
Polymeric micelles for polynucleotide encapsulation
|
JP5769701B2
(ja)
|
2009-05-05 |
2015-08-26 |
テクミラ ファーマシューティカルズ コーポレイションTekmira Pharmaceuticals Corporation |
脂質組成物
|
CN102481376B
(zh)
|
2009-05-27 |
2016-12-21 |
西莱克塔生物科技公司 |
免疫调节剂-聚合物化合物
|
KR102205886B1
(ko)
|
2009-06-10 |
2021-01-21 |
알닐람 파마슈티칼스 인코포레이티드 |
향상된 지질 조성물
|
US9937196B2
(en)
|
2009-06-19 |
2018-04-10 |
University Of Maryland, College Park |
Genomic sequence of avian paramyxovirus type 2 and uses thereof
|
AU2010264686A1
(en)
|
2009-06-24 |
2012-01-19 |
Glaxosmithkline Biologicals S.A. |
Vaccine
|
EP2449114B9
(en)
|
2009-07-01 |
2017-04-19 |
Protiva Biotherapeutics Inc. |
Novel lipid formulations for delivery of therapeutic agents to solid tumors
|
CA2766907A1
(en)
|
2009-07-06 |
2011-01-13 |
Novartis Ag |
Self replicating rna molecules and uses thereof
|
US20110053829A1
(en)
|
2009-09-03 |
2011-03-03 |
Curevac Gmbh |
Disulfide-linked polyethyleneglycol/peptide conjugates for the transfection of nucleic acids
|
RU2573409C2
(ru)
|
2009-11-04 |
2016-01-20 |
Дзе Юниверсити Оф Бритиш Коламбиа |
Содержащие нуклеиновые кислоты липидные частицы и относящиеся к ним способы
|
US8449916B1
(en)
|
2009-11-06 |
2013-05-28 |
Iowa State University Research Foundation, Inc. |
Antimicrobial compositions and methods
|
GB0920304D0
(en)
|
2009-11-20 |
2010-01-06 |
Medical Res Council |
Novel liposome nanoparticles for tumour magnetic resonance imaging
|
TR201901311T4
(tr)
|
2009-12-01 |
2019-02-21 |
Translate Bio Inc |
İnsan genetik hastalıklarında mRNA'nın teslimi için steroid türevi.
|
WO2011069529A1
(en)
|
2009-12-09 |
2011-06-16 |
Curevac Gmbh |
Mannose-containing solution for lyophilization, transfection and/or injection of nucleic acids
|
EA201290499A1
(ru)
|
2009-12-15 |
2013-01-30 |
Байнд Байосайенсиз, Инк. |
Композиции терапевтических полимерных наночастиц с высокой температурой стеклования и высокомолекулярными сополимерами
|
WO2011084518A2
(en)
|
2009-12-15 |
2011-07-14 |
Bind Biosciences, Inc. |
Therapeutic polymeric nanoparticles comprising corticosteroids and methods of making and using same
|
JP5898627B2
(ja)
|
2009-12-15 |
2016-04-06 |
バインド セラピューティックス インコーポレイテッド |
エポチロンを含む治療用ポリマーナノ粒子ならびにそれを製造および使用する方法
|
DE102009058769A1
(de)
|
2009-12-16 |
2011-06-22 |
MagForce Nanotechnologies AG, 10589 |
Temperaturabhängige Aktivierung von katalytischen Nukleinsäuren zur kontrollierten Wirkstofffreisetzung
|
WO2012082165A1
(en)
|
2010-01-24 |
2012-06-21 |
Novartis Ag |
Irradiated biodegradable polymer microparticles
|
US20110262491A1
(en)
|
2010-04-12 |
2011-10-27 |
Selecta Biosciences, Inc. |
Emulsions and methods of making nanocarriers
|
EP2387999A1
(en)
|
2010-05-21 |
2011-11-23 |
CureVac GmbH |
Histidine-containing solution for transfection and/or injection of nucleic acids and uses thereof
|
WO2011149733A2
(en)
|
2010-05-24 |
2011-12-01 |
Merck Sharp & Dohme Corp. |
Novel amino alcohol cationic lipids for oligonucleotide delivery
|
AU2011258156B2
(en)
|
2010-05-26 |
2016-11-24 |
Selecta Biosciences, Inc. |
Multivalent synthetic nanocarrier vaccines
|
WO2011150320A2
(en)
|
2010-05-27 |
2011-12-01 |
University Of Georgia Research Foundation, Inc. |
Activators of innate immunity
|
US8748667B2
(en)
|
2010-06-04 |
2014-06-10 |
Sirna Therapeutics, Inc. |
Low molecular weight cationic lipids for oligonucleotide delivery
|
BRPI1001959A2
(pt)
|
2010-06-15 |
2012-03-06 |
Instituto De Pesquisas Tecnológicas Do Est. S. Paulo S/a - Ipt |
Nanocarreadores coloidais para ativos hidrofílicos e processo de produção
|
WO2011163483A2
(en)
|
2010-06-25 |
2011-12-29 |
Massachusetts Institute Of Technology |
Polymers for biomaterials and therapeutics
|
KR101130137B1
(ko)
|
2010-07-02 |
2012-03-28 |
연세대학교 산학협력단 |
발광다이오드 모듈
|
US9192661B2
(en)
|
2010-07-06 |
2015-11-24 |
Novartis Ag |
Delivery of self-replicating RNA using biodegradable polymer particles
|
US9770463B2
(en)
|
2010-07-06 |
2017-09-26 |
Glaxosmithkline Biologicals Sa |
Delivery of RNA to different cell types
|
PL3243526T3
(pl)
|
2010-07-06 |
2020-05-18 |
Glaxosmithkline Biologicals S.A. |
Dostarczanie rna w celu wyzwolenia wielu szlaków immunologicznych
|
US10487332B2
(en)
*
|
2010-07-06 |
2019-11-26 |
Glaxosmithkline Biologicals Sa |
Immunisation of large mammals with low doses of RNA
|
EP2955230A1
(en)
|
2010-07-30 |
2015-12-16 |
CureVac AG |
Complexation of nucleic acids with disulfide-crosslinked cationic components for transfection and immunostimulation
|
WO2012019168A2
(en)
|
2010-08-06 |
2012-02-09 |
Moderna Therapeutics, Inc. |
Engineered nucleic acids and methods of use thereof
|
WO2012021516A2
(en)
|
2010-08-09 |
2012-02-16 |
The Trustees Of The University Of Pennsylvania |
Nanoparticle-oligonucletide hybrid structures and methods of use thereof
|
WO2012019630A1
(en)
|
2010-08-13 |
2012-02-16 |
Curevac Gmbh |
Nucleic acid comprising or coding for a histone stem-loop and a poly(a) sequence or a polyadenylation signal for increasing the expression of an encoded protein
|
US8956646B2
(en)
|
2010-08-14 |
2015-02-17 |
The Regents Of The University Of California |
Zwitterionic lipids
|
AU2011291522A1
(en)
|
2010-08-20 |
2013-01-24 |
Selecta Biosciences, Inc. |
Synthetic nanocarrier vaccines comprising peptides obtained or derived from human influenza A virus M2E
|
DK3981427T3
(da)
*
|
2010-08-31 |
2022-07-11 |
Glaxosmithkline Biologicals Sa |
Pegylerede liposomer til afgivelse af immunogen-kodende RNA
|
ES2727583T3
(es)
|
2010-08-31 |
2019-10-17 |
Glaxosmithkline Biologicals Sa |
Lípidos adecuados para la administración liposómica de ARN que codifica proteínas
|
FI4043040T3
(fi)
|
2010-08-31 |
2023-04-04 |
Glaxosmithkline Biologicals Sa |
Pieniä liposomeja immunogeeniä koodaavan rna:n toimittamiseksi
|
WO2012039979A2
(en)
|
2010-09-10 |
2012-03-29 |
The Johns Hopkins University |
Rapid diffusion of large polymeric nanoparticles in the mammalian brain
|
DE19177059T1
(de)
|
2010-10-01 |
2021-10-07 |
Modernatx, Inc. |
N1-methyl-pseudouracile enthältendes ribonucleinsäuren sowie ihre verwendungen
|
US20150056300A1
(en)
|
2010-10-22 |
2015-02-26 |
Bind Therapeutics, Inc. |
Therapeutic nanoparticles with high molecular weight copolymers
|
AU2011323250B2
(en)
|
2010-11-05 |
2015-11-19 |
The Johns Hopkins University |
Compositions and methods relating to reduced mucoadhesion
|
WO2012089231A1
(en)
*
|
2010-12-30 |
2012-07-05 |
Okairòs Ag |
Paramyxovirus vaccines
|
US20120177701A1
(en)
|
2010-12-31 |
2012-07-12 |
Selecta Biosciences, Inc. |
Compositions comprising immunostimulatory nucleic acids and related methods
|
DK3202760T3
(da)
|
2011-01-11 |
2019-11-25 |
Alnylam Pharmaceuticals Inc |
Pegylerede lipider og deres anvendelse til lægemiddelfremføring
|
US20120189700A1
(en)
|
2011-01-19 |
2012-07-26 |
Zoraida Aguilar |
Nanoparticle Based Immunological Stimulation
|
JP2014505477A
(ja)
|
2011-01-28 |
2014-03-06 |
メディミューン,エルエルシー |
哺乳類細胞中の可溶性ウイルス融合糖タンパク質の発現
|
US20140066363A1
(en)
|
2011-02-07 |
2014-03-06 |
Arun K. Bhunia |
Carbohydrate nanoparticles for prolonged efficacy of antimicrobial peptide
|
WO2012116715A1
(en)
|
2011-03-02 |
2012-09-07 |
Curevac Gmbh |
Vaccination in newborns and infants
|
WO2012116714A1
(en)
|
2011-03-02 |
2012-09-07 |
Curevac Gmbh |
Vaccination in elderly patients
|
AU2012237260A1
(en)
|
2011-03-31 |
2013-11-14 |
Ingell Technologies Holding B.V. |
Biodegradable compositions suitable for controlled release
|
DE12722942T1
(de)
|
2011-03-31 |
2021-09-30 |
Modernatx, Inc. |
Freisetzung und formulierung von manipulierten nukleinsäuren
|
EP2691078A1
(en)
|
2011-03-31 |
2014-02-05 |
Ingell Technologies Holding B.V. |
Biodegradable compositions suitable for controlled release
|
AU2012255913A1
(en)
|
2011-05-17 |
2013-11-21 |
Moderna Therapeutics, Inc. |
Engineered nucleic acids and methods of use thereof for non-human vertebrates
|
US8691750B2
(en)
|
2011-05-17 |
2014-04-08 |
Axolabs Gmbh |
Lipids and compositions for intracellular delivery of biologically active compounds
|
WO2012166923A2
(en)
|
2011-05-31 |
2012-12-06 |
Bind Biosciences |
Drug loaded polymeric nanoparticles and methods of making and using same
|
ES2685333T3
(es)
|
2011-06-02 |
2018-10-08 |
The Regents Of The University Of California |
Nanopartículas encapsuladas en membrana y método de utilización
|
US8916696B2
(en)
|
2011-06-12 |
2014-12-23 |
City Of Hope |
Aptamer-mRNA conjugates for targeted protein or peptide expression and methods for their use
|
JP6018197B2
(ja)
|
2011-07-21 |
2016-11-02 |
クローダ インターナショナル パブリック リミティド カンパニー |
分枝状ポリエーテル−ポリアミドブロックコポリマー並びにそれらの製造方法及び使用方法
|
WO2013019658A2
(en)
|
2011-07-29 |
2013-02-07 |
Selecta Biosciences, Inc. |
Synthetic nanocarriers comprising polymers comprising multiple immunomodulatory agents
|
CA2842039A1
(en)
|
2011-08-26 |
2013-03-07 |
Arrowhead Research Corporation |
Poly(vinyl ester) polymers for in vivo nucleic acid delivery
|
JP2014527071A
(ja)
|
2011-08-31 |
2014-10-09 |
マリンクロッド エルエルシー |
H−ホスホネートによるナノ粒子pegの改変
|
TR201900264T4
(tr)
|
2011-08-31 |
2019-02-21 |
Glaxosmithkline Biologicals Sa |
İmmünojen şifreleyici rna'nın verilmesi için pegile edilmiş lipozomlar.
|
US9464124B2
(en)
|
2011-09-12 |
2016-10-11 |
Moderna Therapeutics, Inc. |
Engineered nucleic acids and methods of use thereof
|
WO2013039861A2
(en)
|
2011-09-12 |
2013-03-21 |
modeRNA Therapeutics |
Engineered nucleic acids and methods of use thereof
|
JP2014531456A
(ja)
|
2011-09-22 |
2014-11-27 |
バインド セラピューティックス インコーポレイテッド |
治療用ナノ粒子と癌を治療する方法
|
WO2013072929A2
(en)
|
2011-09-23 |
2013-05-23 |
Indian Institute Of Technology |
Nanop article based cosmetic composition
|
JP6113737B2
(ja)
|
2011-10-03 |
2017-04-12 |
モデルナティエックス インコーポレイテッドModernaTX,Inc. |
修飾型のヌクレオシド、ヌクレオチドおよび核酸、ならびにそれらの使用方法
|
WO2013055905A1
(en)
|
2011-10-11 |
2013-04-18 |
Novartis Ag |
Recombinant self-replicating polycistronic rna molecules
|
MX2014004415A
(es)
|
2011-10-14 |
2015-06-05 |
Stc Unm |
Bicapas lipidicas soportadas por nanoparticulas porosas (protecelulas) para suministro dirigido, incluido el suministro transdermico de carga, y los metodos relacionados.
|
ES2745373T3
(es)
|
2011-10-18 |
2020-03-02 |
Dicerna Pharmaceuticals Inc |
Lípidos catiónicos de amina y uso de los mismos
|
WO2013059922A1
(en)
|
2011-10-25 |
2013-05-02 |
The University Of British Columbia |
Limit size lipid nanoparticles and related methods
|
CA3119789A1
(en)
|
2011-10-27 |
2013-05-02 |
Massachusetts Institute Of Technology |
Amino acid derivatives functionalized on the n-terminal capable of forming drug encapsulating microspheres
|
CA2851828A1
(en)
|
2011-10-28 |
2013-05-02 |
Presage Biosciences, Inc. |
Methods for drug delivery
|
WO2013078199A2
(en)
|
2011-11-23 |
2013-05-30 |
Children's Medical Center Corporation |
Methods for enhanced in vivo delivery of synthetic, modified rnas
|
EP2785326A2
(en)
|
2011-11-29 |
2014-10-08 |
The University of North Carolina at Chapel Hill |
Geometrically engineered particles and methods for modulating macrophage or immune responses
|
WO2013086373A1
(en)
|
2011-12-07 |
2013-06-13 |
Alnylam Pharmaceuticals, Inc. |
Lipids for the delivery of active agents
|
EP2791159A4
(en)
|
2011-12-14 |
2015-10-14 |
Moderna Therapeutics Inc |
MODIFIED NUCLEIC ACIDS, AND SHORT-TERM CARE USES THEREOF
|
US20140378538A1
(en)
|
2011-12-14 |
2014-12-25 |
Moderma Therapeutics, Inc. |
Methods of responding to a biothreat
|
MX2014007233A
(es)
*
|
2011-12-16 |
2015-02-04 |
Moderna Therapeutics Inc |
Composiciones de nucleosidos, nucleotidos y acidos nucleicos modificados.
|
WO2013090601A2
(en)
|
2011-12-16 |
2013-06-20 |
Massachusetts Institute Of Technology |
Compact nanoparticles for biological applications
|
CN104968354A
(zh)
|
2011-12-21 |
2015-10-07 |
现代治疗公司 |
增加器官或器官外植体的活力或寿命的方法
|
EP4372081A2
(en)
|
2011-12-30 |
2024-05-22 |
Cellscript, Llc |
Making and using in vitro-synthesized ssrna for introducing into mammalian cells to induce a biological or biochemical effect
|
WO2013105101A1
(en)
|
2012-01-13 |
2013-07-18 |
Department Of Biotechnology |
Solid lipid nanoparticles entrapping hydrophilic/ amphiphilic drug and a process for preparing the same
|
CN104936620B
(zh)
|
2012-01-19 |
2019-08-09 |
约翰霍普金斯大学 |
增强粘膜渗透的纳米粒子调配物
|
EP3312155B1
(en)
|
2012-02-03 |
2020-08-05 |
Rutgers, The State University of New Jersey |
Polymeric biomaterials derived from phenolic monomers and their medical uses
|
KR102019297B1
(ko)
|
2012-02-09 |
2019-09-06 |
라이프 테크놀로지스 코포레이션 |
친수성 중합체성 입자 및 그의 제조 방법
|
US20150337068A1
(en)
|
2012-02-10 |
2015-11-26 |
Karl K Berggren |
Preparation, purification and use of high-x diblock copolymers
|
WO2013120499A1
(en)
|
2012-02-15 |
2013-08-22 |
Curevac Gmbh |
Nucleic acid comprising or coding for a histone stem-loop and a poly (a) sequence or a polyadenylation signal for increasing the expression of an encoded pathogenic antigen
|
WO2013120497A1
(en)
|
2012-02-15 |
2013-08-22 |
Curevac Gmbh |
Nucleic acid comprising or coding for a histone stem-loop and a poly(a) sequence or a polyadenylation signal for increasing the expression of an encoded therapeutic protein
|
CN104394853B
(zh)
|
2012-02-19 |
2017-10-10 |
纳维基因股份有限公司 |
多孔性纳米结构在递送中的用途
|
US10322089B2
(en)
|
2012-03-14 |
2019-06-18 |
The Board Of Trustees Of The Leland Stanford Junior University |
Nanoparticles, nanoparticle delivery methods, and systems of delivery
|
AU2013237874B2
(en)
|
2012-03-29 |
2018-01-18 |
Translate Bio, Inc. |
Lipid-derived neutral nanoparticles
|
US9283287B2
(en)
|
2012-04-02 |
2016-03-15 |
Moderna Therapeutics, Inc. |
Modified polynucleotides for the production of nuclear proteins
|
US10501513B2
(en)
|
2012-04-02 |
2019-12-10 |
Modernatx, Inc. |
Modified polynucleotides for the production of oncology-related proteins and peptides
|
EP2834259A4
(en)
|
2012-04-02 |
2016-08-24 |
Moderna Therapeutics Inc |
MODIFIED POLYNUCLEOTIDES
|
US10501512B2
(en)
|
2012-04-02 |
2019-12-10 |
Modernatx, Inc. |
Modified polynucleotides
|
EP2858679B1
(en)
*
|
2012-06-08 |
2021-02-24 |
Translate Bio, Inc. |
Pulmonary delivery of mrna to non-lung target cells
|
CA2873274C
(en)
|
2012-06-08 |
2021-06-01 |
Ethris Gmbh |
Pulmonary delivery of messenger rna
|
WO2014028429A2
(en)
|
2012-08-14 |
2014-02-20 |
Moderna Therapeutics, Inc. |
Enzymes and polymerases for the synthesis of rna
|
CA2892529C
(en)
|
2012-11-26 |
2023-04-25 |
Moderna Therapeutics, Inc. |
Terminally modified rna
|
US20150366997A1
(en)
*
|
2012-12-07 |
2015-12-24 |
Shire Human Genetics Therapies, Inc. |
COMPOSITIONS AND METHODS FOR mRNA DELIVERY
|
CA2891911C
(en)
|
2012-12-07 |
2023-03-07 |
Alnylam Pharmaceuticals, Inc. |
Improved nucleic acid lipid particle formulations
|
EP2931319B1
(en)
|
2012-12-13 |
2019-08-21 |
ModernaTX, Inc. |
Modified nucleic acid molecules and uses thereof
|
WO2014093574A1
(en)
|
2012-12-13 |
2014-06-19 |
Moderna Therapeutics, Inc. |
Modified polynucleotides for altering cell phenotype
|
MX2015011955A
(es)
|
2013-03-08 |
2016-04-07 |
Novartis Ag |
Lipidos y composiciones de lipidos para el suministro de agentes activos.
|
KR20220139415A
(ko)
|
2013-03-13 |
2022-10-14 |
더 유나이티드 스테이츠 오브 어메리카, 애즈 리프리젠티드 바이 더 세크러테리, 디파트먼트 오브 헬쓰 앤드 휴먼 서비씨즈 |
선융합(prefusion) RSV F 단백질 및 이의 용도
|
US20160024181A1
(en)
|
2013-03-13 |
2016-01-28 |
Moderna Therapeutics, Inc. |
Long-lived polynucleotide molecules
|
ES2692363T3
(es)
|
2013-03-14 |
2018-12-03 |
Translate Bio, Inc. |
Composiciones terapéuticas de ARNm y su uso para tratar enfermedades y trastornos
|
US10258698B2
(en)
|
2013-03-14 |
2019-04-16 |
Modernatx, Inc. |
Formulation and delivery of modified nucleoside, nucleotide, and nucleic acid compositions
|
US20160032316A1
(en)
|
2013-03-14 |
2016-02-04 |
The Trustees Of The University Of Pennsylvania |
Purification and Purity Assessment of RNA Molecules Synthesized with Modified Nucleosides
|
SI2970456T1
(sl)
*
|
2013-03-14 |
2022-01-31 |
Translate Bio, Inc. |
Postopki in sestavki za dostavo MRNA-kodiranih protiteles
|
ES2670529T3
(es)
*
|
2013-03-15 |
2018-05-30 |
Translate Bio, Inc. |
Mejora sinergística de la entrega de ácidos nucleicos a través de formulaciones mezcladas
|
WO2014172045A1
(en)
|
2013-03-15 |
2014-10-23 |
The University Of British Columbia |
Lipid nanoparticles for transfection and related methods
|
US8980864B2
(en)
|
2013-03-15 |
2015-03-17 |
Moderna Therapeutics, Inc. |
Compositions and methods of altering cholesterol levels
|
WO2014152031A1
(en)
|
2013-03-15 |
2014-09-25 |
Moderna Therapeutics, Inc. |
Ribonucleic acid purification
|
US9693958B2
(en)
|
2013-03-15 |
2017-07-04 |
Cureport, Inc. |
Methods and devices for preparation of lipid nanoparticles
|
EP2983804A4
(en)
|
2013-03-15 |
2017-03-01 |
Moderna Therapeutics, Inc. |
Ion exchange purification of mrna
|
US10077439B2
(en)
|
2013-03-15 |
2018-09-18 |
Modernatx, Inc. |
Removal of DNA fragments in mRNA production process
|
WO2014144711A1
(en)
|
2013-03-15 |
2014-09-18 |
Moderna Therapeutics, Inc. |
Analysis of mrna heterogeneity and stability
|
EP3578663A1
(en)
|
2013-03-15 |
2019-12-11 |
ModernaTX, Inc. |
Manufacturing methods for production of rna transcripts
|
WO2014144039A1
(en)
|
2013-03-15 |
2014-09-18 |
Moderna Therapeutics, Inc. |
Characterization of mrna molecules
|
WO2014144153A2
(en)
|
2013-03-15 |
2014-09-18 |
Ohio State Innovation Foundation |
Metapneumovirus immunogens and related materials and methods
|
TW201534578A
(zh)
|
2013-07-08 |
2015-09-16 |
Daiichi Sankyo Co Ltd |
新穎脂質
|
JP7019233B2
(ja)
|
2013-07-11 |
2022-02-15 |
モデルナティエックス インコーポレイテッド |
CRISPR関連タンパク質をコードする合成ポリヌクレオチドおよび合成sgRNAを含む組成物ならびに使用方法
|
CN105473157A
(zh)
|
2013-08-21 |
2016-04-06 |
库瑞瓦格股份公司 |
组合疫苗
|
SG10201801428RA
(en)
|
2013-08-21 |
2018-03-28 |
Curevac Ag |
Method for increasing expression of rna-encoded proteins
|
AU2014310934B2
(en)
|
2013-08-21 |
2019-09-12 |
CureVac SE |
Respiratory syncytial virus (RSV) vaccine
|
EP3041938A1
(en)
|
2013-09-03 |
2016-07-13 |
Moderna Therapeutics, Inc. |
Circular polynucleotides
|
WO2015048744A2
(en)
|
2013-09-30 |
2015-04-02 |
Moderna Therapeutics, Inc. |
Polynucleotides encoding immune modulating polypeptides
|
EP3052511A4
(en)
|
2013-10-02 |
2017-05-31 |
Moderna Therapeutics, Inc. |
Polynucleotide molecules and uses thereof
|
CA2926218A1
(en)
|
2013-10-03 |
2015-04-09 |
Moderna Therapeutics, Inc. |
Polynucleotides encoding low density lipoprotein receptor
|
AU2014337156A1
(en)
|
2013-10-18 |
2016-05-12 |
Modernatx, Inc. |
Compositions and methods for tolerizing cellular systems
|
JP6412131B2
(ja)
|
2013-11-29 |
2018-10-24 |
ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア |
MERS‐CoVワクチン
|
EP3083556B1
(en)
*
|
2013-12-19 |
2019-12-25 |
Novartis AG |
Lipids and lipid compositions for the delivery of active agents
|
US10426737B2
(en)
|
2013-12-19 |
2019-10-01 |
Novartis Ag |
Lipids and lipid compositions for the delivery of active agents
|
DK3090053T3
(en)
|
2013-12-30 |
2019-02-25 |
Curevac Ag |
Artificial nucleic acid molecules
|
CA2927254C
(en)
|
2013-12-30 |
2023-10-24 |
Curevac Ag |
Artificial nucleic acid molecules
|
WO2015130584A2
(en)
*
|
2014-02-25 |
2015-09-03 |
Merck Sharp & Dohme Corp. |
Lipid nanoparticle vaccine adjuvants and antigen delivery systems
|
WO2015143335A1
(en)
|
2014-03-20 |
2015-09-24 |
The University Of North Carolina At Chapel Hill |
Methods and compositions for chimeric coronavirus spike proteins
|
RU2746406C2
(ru)
|
2014-04-23 |
2021-04-13 |
МОДЕРНАТиЭкс, ИНК. |
Вакцины на основе нуклеиновых кислот
|
US10286086B2
(en)
|
2014-06-19 |
2019-05-14 |
Modernatx, Inc. |
Alternative nucleic acid molecules and uses thereof
|
US20170204152A1
(en)
|
2014-07-16 |
2017-07-20 |
Moderna Therapeutics, Inc. |
Chimeric polynucleotides
|
WO2016011306A2
(en)
|
2014-07-17 |
2016-01-21 |
Moderna Therapeutics, Inc. |
Terminal modifications of polynucleotides
|
EP3236998A1
(en)
|
2014-12-24 |
2017-11-01 |
The U.S.A. as represented by the Secretary, Department of Health and Human Services |
Recombinant metapneumovirus f proteins and their use
|
WO2016118724A1
(en)
|
2015-01-21 |
2016-07-28 |
Moderna Therapeutics, Inc. |
Lipid nanoparticle compositions
|
CA2975853A1
(en)
|
2015-02-08 |
2016-08-11 |
Tongli Biomedical Co., Ltd. |
Lipid nanoparticles and uses thereof
|
EP3261665A1
(en)
|
2015-02-24 |
2018-01-03 |
The United States of America, as represented by The Secretary, Department of Health and Human Services |
Middle east respiratory syndrome coronavirus immunogens, antibodies, and their use
|
WO2016164762A1
(en)
|
2015-04-08 |
2016-10-13 |
Moderna Therapeutics, Inc. |
Polynucleotides encoding low density lipoprotein receptor egf-a and intracellular domain mutants and methods of using the same
|
EP3307305A4
(en)
|
2015-06-10 |
2019-05-22 |
Modernatx, Inc. |
TARGETED ADAPTIVE VACCINES
|
WO2017011773A2
(en)
|
2015-07-15 |
2017-01-19 |
Modernatx, Inc. |
Codon-optimized nucleic acids encoding antibodies
|
MA42502A
(fr)
|
2015-07-21 |
2018-05-30 |
Modernatx Inc |
Vaccins contre une maladie infectieuse
|
WO2017015457A1
(en)
|
2015-07-21 |
2017-01-26 |
Modernatx, Inc. |
Ebola vaccine
|
WO2017019935A1
(en)
|
2015-07-30 |
2017-02-02 |
Modernatx, Inc. |
Multimeric mrna
|
US20190008938A1
(en)
|
2015-07-30 |
2019-01-10 |
Modernatx, Inc. |
Concatemeric peptide epitope rnas
|
US20180237849A1
(en)
|
2015-08-17 |
2018-08-23 |
Modernatx, Inc. |
Rna mapping/fingerprinting
|
US11564893B2
(en)
|
2015-08-17 |
2023-01-31 |
Modernatx, Inc. |
Methods for preparing particles and related compositions
|
US11311615B2
(en)
|
2015-09-16 |
2022-04-26 |
Shin Nippon Biomedical Laboratories, Ltd. |
Vaccine compositions
|
RS63030B1
(sr)
|
2015-09-17 |
2022-04-29 |
Modernatx Inc |
Jedinjenja i kompozicije za intracelularno isporučivanje terapeutskih sredstava
|
AU2016336344A1
(en)
|
2015-10-05 |
2018-04-19 |
Modernatx, Inc. |
Methods for therapeutic administration of messenger ribonucleic acid drugs
|
WO2017066789A1
(en)
|
2015-10-16 |
2017-04-20 |
Modernatx, Inc. |
Mrna cap analogs with modified sugar
|
HRP20220872T1
(hr)
|
2015-10-22 |
2022-12-23 |
Modernatx, Inc. |
Cjepiva protiv respiratornih virusa
|
EP3364950A4
(en)
|
2015-10-22 |
2019-10-23 |
ModernaTX, Inc. |
VACCINES AGAINST TROPICAL DISEASES
|
CA3003090A1
(en)
|
2015-10-22 |
2017-04-27 |
Modernatx, Inc. |
Cancer vaccines
|
PE20181529A1
(es)
|
2015-10-22 |
2018-09-26 |
Modernatx Inc |
Vacunas de acido nucleico para el virus varicela-zoster (vzv)
|
WO2017070620A2
(en)
|
2015-10-22 |
2017-04-27 |
Modernatx, Inc. |
Broad spectrum influenza virus vaccine
|
US20180303929A1
(en)
|
2015-10-22 |
2018-10-25 |
Moderna TX, Inc. |
Herpes simplex virus vaccine
|
WO2017070613A1
(en)
|
2015-10-22 |
2017-04-27 |
Modernatx, Inc. |
Human cytomegalovirus vaccine
|
AU2016342376A1
(en)
|
2015-10-22 |
2018-06-07 |
Modernatx, Inc. |
Sexually transmitted disease vaccines
|
BR112018008102A2
(pt)
|
2015-10-22 |
2018-11-06 |
Modernatx Inc |
vacina de vírus sincicial respiratório
|
CA3003267A1
(en)
|
2015-10-26 |
2017-05-04 |
Translate Bio Ma, Inc. |
Nanoparticle formulations for delivery of nucleic acid complexes
|
WO2017075531A1
(en)
|
2015-10-28 |
2017-05-04 |
Acuitas Therapeutics, Inc. |
Novel lipids and lipid nanoparticle formulations for delivery of nucleic acids
|
WO2017081082A2
(en)
|
2015-11-09 |
2017-05-18 |
Curevac Ag |
Optimized nucleic acid molecules
|
MD3386484T2
(ro)
|
2015-12-10 |
2022-11-30 |
Modernatx Inc |
Compoziții și metode de livrare a unor agenți terapeutici
|
EP3390630A1
(en)
|
2015-12-17 |
2018-10-24 |
Modernatx, Inc. |
POLYNUCLEOTIDES ENCODING METHYLMALONYL-CoA MUTASE
|
JP7114465B2
(ja)
|
2015-12-22 |
2022-08-08 |
モデルナティエックス インコーポレイテッド |
薬剤の細胞内送達のための化合物および組成物
|
US10465190B1
(en)
|
2015-12-23 |
2019-11-05 |
Modernatx, Inc. |
In vitro transcription methods and constructs
|
WO2017127750A1
(en)
|
2016-01-22 |
2017-07-27 |
Modernatx, Inc. |
Messenger ribonucleic acids for the production of intracellular binding polypeptides and methods of use thereof
|
MX2018012095A
(es)
|
2016-04-05 |
2019-01-10 |
Janssen Vaccines & Prevention Bv |
Vacuna contra vrs.
|
CA3024507A1
(en)
|
2016-05-18 |
2017-11-23 |
Modernatx, Inc. |
Polynucleotides encoding .alpha.-galactosidase a for the treatment of fabry disease
|
US11001861B2
(en)
|
2016-05-18 |
2021-05-11 |
Modernatx, Inc. |
Polynucleotides encoding galactose-1-phosphate uridylyltransferase for the treatment of galactosemia type 1
|
WO2017201317A1
(en)
|
2016-05-18 |
2017-11-23 |
Modernatx, Inc. |
Polyribonucleotides containing reduced uracil content and uses thereof
|
US20200085916A1
(en)
|
2016-05-18 |
2020-03-19 |
Modernatx, Inc. |
Polynucleotides encoding porphobilinogen deaminase for the treatment of acute intermittent porphyria
|
EP3458107B1
(en)
|
2016-05-18 |
2024-03-13 |
ModernaTX, Inc. |
Polynucleotides encoding jagged1 for the treatment of alagille syndrome
|
US20190390181A1
(en)
|
2016-05-18 |
2019-12-26 |
Modernatx, Inc. |
Polynucleotides Encoding Lipoprotein Lipase for the Treatment of Hyperlipidemia
|
AU2017268396B2
(en)
|
2016-05-18 |
2023-05-18 |
Modernatx, Inc. |
Polynucleotides encoding citrin for the treatment of citrullinemia type 2
|
CA3024509A1
(en)
|
2016-05-18 |
2017-11-23 |
Modernatx, Inc. |
Mrna combination therapy for the treatment of cancer
|
BR112018073683A2
(pt)
|
2016-05-18 |
2019-02-26 |
Modernatx, Inc. |
polinucleotídeos codificadores de relaxina
|
EP3458108A4
(en)
|
2016-05-18 |
2020-04-22 |
ModernaTX, Inc. |
POLYNUCLEOTIDES FOR CODING THE TRANSMEMBRANE CONDUCTIVE REGULATOR OF CYSTIC FIBROSE FOR TREATING CYSTIC FIBROSE
|
JP7246930B2
(ja)
|
2016-05-18 |
2023-03-28 |
モデルナティエックス インコーポレイテッド |
インターロイキン-12(il12)をコードするポリヌクレオチドおよびその使用
|
WO2017201332A1
(en)
|
2016-05-18 |
2017-11-23 |
Modernatx, Inc. |
Polynucleotides encoding acyl-coa dehydrogenase, very long-chain for the treatment of very long-chain acyl-coa dehydrogenase deficiency
|
EP3468537A1
(en)
|
2016-06-14 |
2019-04-17 |
Modernatx, Inc. |
Stabilized formulations of lipid nanoparticles
|
AU2017286980B2
(en)
|
2016-06-30 |
2023-10-26 |
Arbutus Biopharma Corporation |
Compositions and methods for delivering messenger RNA
|
MX2019002904A
(es)
|
2016-09-14 |
2019-09-26 |
Modernatx Inc |
Composiciones de arn de alta pureza y métodos para su preparación.
|
WO2018075980A1
(en)
|
2016-10-21 |
2018-04-26 |
Modernatx, Inc. |
Human cytomegalovirus vaccine
|
JP7289265B2
(ja)
|
2016-10-26 |
2023-06-09 |
キュアバック エスイー |
脂質ナノ粒子mRNAワクチン
|
JP2019532657A
(ja)
|
2016-10-26 |
2019-11-14 |
モデルナティーエックス, インコーポレイテッド |
免疫応答を増強するためのメッセンジャーリボ核酸及びその使用方法
|
MA46643A
(fr)
|
2016-10-26 |
2019-09-04 |
Modernatx Inc |
Méthodes et compositions pour le mappage d'arn
|
US11583504B2
(en)
|
2016-11-08 |
2023-02-21 |
Modernatx, Inc. |
Stabilized formulations of lipid nanoparticles
|
CN110167587A
(zh)
|
2016-11-11 |
2019-08-23 |
摩登纳特斯有限公司 |
流感疫苗
|
EP3551193A4
(en)
|
2016-12-08 |
2020-08-19 |
Modernatx, Inc. |
NUCLEIC ACID VACCINES AGAINST RESPIRATORY VIRUSES
|
WO2018111967A1
(en)
|
2016-12-13 |
2018-06-21 |
Modernatx, Inc. |
Rna affinity purification
|
US11524066B2
(en)
|
2016-12-23 |
2022-12-13 |
CureVac SE |
Henipavirus vaccine
|
US20180243225A1
(en)
|
2017-01-25 |
2018-08-30 |
Modernatx, Inc. |
Ebola/marburg vaccines
|
EP3577221A4
(en)
|
2017-02-01 |
2020-12-23 |
ModernaTX, Inc. |
SECONDARY POLYNUCLEOTIDE STRUCTURE
|
BR112019015797A2
(pt)
|
2017-02-01 |
2020-03-17 |
Modernatx, Inc. |
Composições de mrna terapêuticas imunomoduladoras que codificam peptídeos de mutação de oncogene de ativação
|
NZ755780A
(en)
|
2017-02-01 |
2023-10-27 |
Modernatx Inc |
Rna cancer vaccines
|
EP3582790A4
(en)
|
2017-02-16 |
2020-11-25 |
ModernaTX, Inc. |
VERY POWERFUL IMMUNOGENIC COMPOSITIONS
|
WO2018157009A1
(en)
|
2017-02-24 |
2018-08-30 |
Modernatx, Inc. |
Nucleic acid-based therapy of muscular dystrophies
|
US11045540B2
(en)
|
2017-03-15 |
2021-06-29 |
Modernatx, Inc. |
Varicella zoster virus (VZV) vaccine
|
JP7332478B2
(ja)
|
2017-03-15 |
2023-08-23 |
モデルナティエックス インコーポレイテッド |
脂質ナノ粒子製剤
|
SG11201907916TA
(en)
|
2017-03-15 |
2019-09-27 |
Modernatx Inc |
Compounds and compositions for intracellular delivery of therapeutic agents
|
WO2018170260A1
(en)
|
2017-03-15 |
2018-09-20 |
Modernatx, Inc. |
Respiratory syncytial virus vaccine
|
US11752206B2
(en)
|
2017-03-15 |
2023-09-12 |
Modernatx, Inc. |
Herpes simplex virus vaccine
|
WO2018170245A1
(en)
|
2017-03-15 |
2018-09-20 |
Modernatx, Inc. |
Broad spectrum influenza virus vaccine
|
WO2018170347A1
(en)
|
2017-03-17 |
2018-09-20 |
Modernatx, Inc. |
Zoonotic disease rna vaccines
|
WO2018175783A1
(en)
|
2017-03-22 |
2018-09-27 |
Modernatx, Inc. |
Rna bacterial vaccines
|
WO2018187590A1
(en)
|
2017-04-05 |
2018-10-11 |
Modernatx, Inc. |
Reduction or elimination of immune responses to non-intravenous, e.g., subcutaneously administered therapeutic proteins
|
WO2018200737A1
(en)
|
2017-04-26 |
2018-11-01 |
Modernatx, Inc. |
Herpes simplex virus vaccine
|
WO2018232355A1
(en)
|
2017-06-15 |
2018-12-20 |
Modernatx, Inc. |
Rna antibodies
|
WO2018232357A1
(en)
|
2017-06-15 |
2018-12-20 |
Modernatx, Inc. |
Rna formulations
|
US20200254086A1
(en)
|
2017-08-18 |
2020-08-13 |
Moderna TX, Inc. |
Efficacious mrna vaccines
|
WO2019036685A1
(en)
|
2017-08-18 |
2019-02-21 |
Modernatx, Inc. |
METHODS FOR HPLC ANALYSIS
|
JP7408098B2
(ja)
|
2017-08-18 |
2024-01-05 |
モデルナティエックス インコーポレイテッド |
Rnaポリメラーゼバリアント
|
EP3668977A4
(en)
|
2017-08-18 |
2021-04-21 |
Modernatx, Inc. |
HPLC ANALYTICAL PROCESSES
|
EP3675817A1
(en)
|
2017-08-31 |
2020-07-08 |
Modernatx, Inc. |
Methods of making lipid nanoparticles
|
WO2019055807A1
(en)
|
2017-09-14 |
2019-03-21 |
Modernatx, Inc. |
RNA VACCINES AGAINST ZIKA VIRUS
|
BR112020008404A2
(pt)
|
2017-10-31 |
2020-11-03 |
Modernatx, Inc. |
nanopartículas lipídicas para a entrega de rna modificado codificando um polipeptídeo vegf-a
|
US20190192646A1
(en)
|
2017-11-03 |
2019-06-27 |
Modernatx, Inc. |
Salmonella vaccines
|
AU2018372922A1
(en)
|
2017-11-21 |
2020-06-11 |
Modernatx, Inc. |
Epstein-Barr virus vaccines
|
US11911453B2
(en)
|
2018-01-29 |
2024-02-27 |
Modernatx, Inc. |
RSV RNA vaccines
|
EP4227319A1
(en)
|
2018-04-17 |
2023-08-16 |
CureVac SE |
Novel rsv rna molecules and compositions for vaccination
|
US20210268086A1
(en)
|
2018-06-27 |
2021-09-02 |
Modernatx, Inc. |
Personalized cancer vaccine epitope selection
|
AU2019338557A1
(en)
|
2018-09-13 |
2021-03-25 |
Modernatx, Inc. |
Modified mRNA for the treatment of progressive familial intrahepatic cholestasis disorders
|
AU2019345067A1
(en)
|
2018-09-19 |
2021-04-08 |
Modernatx, Inc. |
High-purity peg lipids and uses thereof
|
JP2022501359A
(ja)
|
2018-09-19 |
2022-01-06 |
モデルナティーエックス, インコーポレイテッド |
Peg脂質及びそれらの使用
|
WO2020061367A1
(en)
|
2018-09-19 |
2020-03-26 |
Modernatx, Inc. |
Compounds and compositions for intracellular delivery of therapeutic agents
|
JP2022501367A
(ja)
|
2018-09-20 |
2022-01-06 |
モデルナティエックス インコーポレイテッドModernaTX, Inc. |
脂質ナノ粒子の調製及びその投与方法
|
JP2022506839A
(ja)
|
2018-11-07 |
2022-01-17 |
モデルナティエックス インコーポレイテッド |
Rnaがんワクチン
|
AU2020214843A1
(en)
|
2019-01-31 |
2021-08-19 |
Modernatx, Inc. |
Methods of preparing lipid nanoparticles
|
US11351242B1
(en)
|
2019-02-12 |
2022-06-07 |
Modernatx, Inc. |
HMPV/hPIV3 mRNA vaccine composition
|
CA3130888A1
(en)
|
2019-02-20 |
2020-08-27 |
Modernatx, Inc. |
Rna polymerase variants for co-transcriptional capping
|
CA3132975A1
(en)
|
2019-03-11 |
2020-09-17 |
Modernatx, Inc. |
Fed-batch in vitro transcription process
|
WO2020190750A1
(en)
|
2019-03-15 |
2020-09-24 |
Modernatx, Inc. |
Hiv rna vaccines
|
BR112021018526A2
(pt)
|
2019-03-19 |
2021-11-23 |
Arcturus Therapeutics Inc |
Método de fabricação de nanopartículas de rna encapsuladas em lipídio
|
US20220236253A1
(en)
|
2019-05-31 |
2022-07-28 |
Modernatx, Inc. |
Expanded t cell assay
|
US20220348900A1
(en)
|
2019-08-14 |
2022-11-03 |
Modernatx, Inc. |
Processes for purifying downstream products of in vitro transcription
|
JP2022547313A
(ja)
|
2019-09-11 |
2022-11-11 |
モデルナティエックス インコーポレイテッド |
ヒトサイトメガロウイルスワクチン
|
EP4031666A4
(en)
|
2019-09-19 |
2023-11-15 |
ModernaTX, Inc. |
CAP GUIDES AND METHODS OF USE FOR RNA MAPPING
|
WO2021055833A1
(en)
|
2019-09-19 |
2021-03-25 |
Modernatx, Inc. |
Branched tail lipid compounds and compositions for intracellular delivery of therapeutic agents
|
CN110974954B
(zh)
|
2019-12-24 |
2021-03-16 |
珠海丽凡达生物技术有限公司 |
一种用于增强核酸疫苗免疫效果的脂质纳米颗粒及其制备方法
|
WO2021142306A1
(en)
|
2020-01-10 |
2021-07-15 |
Modernatx, Inc. |
Variational autoencoder for biological sequence generation
|
US20210228707A1
(en)
|
2020-01-28 |
2021-07-29 |
Modernatx, Inc. |
Coronavirus rna vaccines
|
MX2022009429A
(es)
|
2020-01-30 |
2022-08-25 |
Modernatx Inc |
Composiciones para la inmunizacion contra virus respiratorios.
|
MX2022009410A
(es)
|
2020-01-31 |
2022-10-18 |
Modernatx Inc |
Metodos de preparacion de nanoparticulas lipidicas.
|
IL295377A
(en)
|
2020-02-07 |
2022-10-01 |
Modernatx Inc |
sars-cov-2 mRNA domain vaccines
|
CN114206827B
(zh)
|
2020-04-09 |
2023-05-23 |
苏州艾博生物科技有限公司 |
脂质纳米颗粒组合物
|
WO2021211343A1
(en)
|
2020-04-13 |
2021-10-21 |
Modernatx, Inc. |
Zika virus mrna vaccines
|
KR20230015351A
(ko)
|
2020-04-22 |
2023-01-31 |
화이자 인코포레이티드 |
코로나바이러스 백신
|
WO2021222304A1
(en)
|
2020-04-27 |
2021-11-04 |
Modernatx, Inc. |
Sars-cov-2 rna vaccines
|
WO2021159130A2
(en)
|
2020-05-15 |
2021-08-12 |
Modernatx, Inc. |
Coronavirus rna vaccines and methods of use
|
JP2023526284A
(ja)
|
2020-05-15 |
2023-06-21 |
トランスレイト バイオ, インコーポレイテッド |
mRNA送達のための脂質ナノ粒子製剤
|
US20230142529A1
(en)
|
2020-05-15 |
2023-05-11 |
Modernatx, Inc. |
Rna formulations for high volume distribution
|
US20230190761A1
(en)
|
2020-05-21 |
2023-06-22 |
Modernatx, Inc. |
Methylene blue stabilized mrna compositions
|
AU2021283934A1
(en)
|
2020-06-05 |
2023-01-19 |
Modernatx, Inc. |
Bacterial strains for DNA production
|
US20230285310A1
(en)
|
2020-08-06 |
2023-09-14 |
Modernatx, Inc. |
Compositions for the delivery of payload molecules to airway epithelium
|
US11406703B2
(en)
|
2020-08-25 |
2022-08-09 |
Modernatx, Inc. |
Human cytomegalovirus vaccine
|
WO2022067010A1
(en)
|
2020-09-25 |
2022-03-31 |
Modernatx, Inc. |
Multi-proline-substituted coronavirus spike protein vaccines
|
JP2023544197A
(ja)
|
2020-10-06 |
2023-10-20 |
トランスレイト バイオ, インコーポレイテッド |
脂質ナノ粒子の改善された方法および製剤
|
TW202233232A
(zh)
|
2020-11-06 |
2022-09-01 |
法商賽諾菲公司 |
遞送mRNA疫苗的脂質奈米顆粒
|
US20240041785A1
(en)
|
2020-11-16 |
2024-02-08 |
BioNTech SE |
Compositions and methods for stabilization of lipid nanoparticle mrna vaccines
|
WO2022137133A1
(en)
|
2020-12-22 |
2022-06-30 |
Curevac Ag |
Rna vaccine against sars-cov-2 variants
|
US20230000970A1
(en)
|
2021-01-11 |
2023-01-05 |
Modernatx, Inc. |
Seasonal rna influenza virus vaccines
|
AU2022208057A1
(en)
|
2021-01-15 |
2023-08-03 |
Modernatx, Inc. |
Variant strain-based coronavirus vaccines
|
WO2022155530A1
(en)
|
2021-01-15 |
2022-07-21 |
Modernatx, Inc. |
Variant strain-based coronavirus vaccines
|
EP4301405A1
(en)
|
2021-03-05 |
2024-01-10 |
ModernaTX, Inc. |
Vlp enteroviral vaccines
|
EP4313072A1
(en)
|
2021-03-26 |
2024-02-07 |
ModernaTX, Inc. |
Pertussis vaccine
|
EP4314000A1
(en)
|
2021-03-31 |
2024-02-07 |
ModernaTX, Inc. |
Synthesis of trinucleotide and tetranucleotide caps for mrna production
|
AU2022249357A1
(en)
|
2021-04-01 |
2023-10-12 |
Modernatx, Inc. |
Methods for identification and ratio determination of rna species in multivalent rna compositions
|
JP2024515035A
(ja)
|
2021-04-01 |
2024-04-04 |
モデルナティエックス インコーポレイテッド |
mRNAによる抗体構造及びアイソタイプの粘膜発現
|
CN117529335A
(zh)
|
2021-04-13 |
2024-02-06 |
摩登纳特斯有限公司 |
爱泼斯坦-巴尔病毒mrna疫苗
|
WO2022221336A1
(en)
|
2021-04-13 |
2022-10-20 |
Modernatx, Inc. |
Respiratory syncytial virus mrna vaccines
|
JP2024514182A
(ja)
|
2021-04-13 |
2024-03-28 |
モデルナティエックス インコーポレイテッド |
呼吸器ウイルス組み合わせワクチン
|
JP2024513999A
(ja)
|
2021-04-14 |
2024-03-27 |
モデルナティエックス インコーポレイテッド |
インフルエンザ-コロナウイルス組み合わせワクチン
|
WO2022232585A1
(en)
|
2021-04-29 |
2022-11-03 |
Modernatx, Inc. |
Lyophilization methods for preparing lipid formulated therapeutics
|
US20220363937A1
(en)
|
2021-05-14 |
2022-11-17 |
Armstrong World Industries, Inc. |
Stabilization of antimicrobial coatings
|
EP4355761A1
(en)
|
2021-06-14 |
2024-04-24 |
ModernaTX, Inc. |
Mrna vaccines encoding flexible coronavirus spike proteins
|
WO2022266012A1
(en)
|
2021-06-14 |
2022-12-22 |
Modernatx, Inc. |
Coronavirus glycosylation variant vaccines
|
WO2022266389A1
(en)
|
2021-06-17 |
2022-12-22 |
Modernatx, Inc. |
Alternative rna purification strategies
|
WO2023283642A2
(en)
|
2021-07-09 |
2023-01-12 |
Modernatx, Inc. |
Pan-human coronavirus concatemeric vaccines
|
WO2023283645A1
(en)
|
2021-07-09 |
2023-01-12 |
Modernatx, Inc. |
Pan-human coronavirus domain vaccines
|
WO2023283651A1
(en)
|
2021-07-09 |
2023-01-12 |
Modernatx, Inc. |
Pan-human coronavirus vaccines
|
WO2023014649A1
(en)
|
2021-08-02 |
2023-02-09 |
Modernatx, Inc. |
Extraction-less reverse phase (rp) chromatography of mrna encapsulated in lipid nanoparticles for mrna purity assessment
|
WO2023018773A1
(en)
|
2021-08-11 |
2023-02-16 |
Modernatx, Inc. |
Lipid nanoparticle formulations and methods of synthesis thereof
|
WO2023019181A1
(en)
|
2021-08-11 |
2023-02-16 |
Modernatx, Inc. |
Sars-cov-2 lipid nanoparticle vaccine formulations
|
TW202321446A
(zh)
|
2021-08-13 |
2023-06-01 |
美商現代公司 |
多管柱層析mRNA純化
|
WO2023092069A1
(en)
|
2021-11-18 |
2023-05-25 |
Modernatx, Inc. |
Sars-cov-2 mrna domain vaccines and methods of use
|
WO2023107999A2
(en)
|
2021-12-08 |
2023-06-15 |
Modernatx, Inc. |
Herpes simplex virus mrna vaccines
|
WO2023114307A1
(en)
|
2021-12-15 |
2023-06-22 |
Modernatx, Inc. |
Determination of encapsulation efficiency of lipid nanoparticles
|
WO2023132885A1
(en)
|
2022-01-04 |
2023-07-13 |
Modernatx, Inc. |
Methods of purifying dna for gene synthesis
|
WO2023137149A1
(en)
|
2022-01-14 |
2023-07-20 |
Modernatx, Inc. |
In vitro transcription dna purification and recycling
|
WO2023150256A1
(en)
|
2022-02-03 |
2023-08-10 |
Modernatx, Inc. |
Continuous precipitation for mrna purification
|