MA46643A - Méthodes et compositions pour le mappage d'arn - Google Patents

Méthodes et compositions pour le mappage d'arn

Info

Publication number
MA46643A
MA46643A MA046643A MA46643A MA46643A MA 46643 A MA46643 A MA 46643A MA 046643 A MA046643 A MA 046643A MA 46643 A MA46643 A MA 46643A MA 46643 A MA46643 A MA 46643A
Authority
MA
Morocco
Prior art keywords
compositions
methods
rna mapping
rna
mapping
Prior art date
Application number
MA046643A
Other languages
English (en)
Inventor
Nicholas J Amato
Serenus Hua
Tao Jiang
Huijuan Li
David Marquardt
Edward John Miracco
Original Assignee
Modernatx Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Modernatx Inc filed Critical Modernatx Inc
Publication of MA46643A publication Critical patent/MA46643A/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6809Methods for determination or identification of nucleic acids involving differential detection
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
MA046643A 2016-10-26 2017-10-26 Méthodes et compositions pour le mappage d'arn MA46643A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201662412932P 2016-10-26 2016-10-26

Publications (1)

Publication Number Publication Date
MA46643A true MA46643A (fr) 2019-09-04

Family

ID=62025494

Family Applications (1)

Application Number Title Priority Date Filing Date
MA046643A MA46643A (fr) 2016-10-26 2017-10-26 Méthodes et compositions pour le mappage d'arn

Country Status (4)

Country Link
US (2) US20180274009A1 (fr)
EP (1) EP3532613A4 (fr)
MA (1) MA46643A (fr)
WO (1) WO2018081462A1 (fr)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9464124B2 (en) 2011-09-12 2016-10-11 Moderna Therapeutics, Inc. Engineered nucleic acids and methods of use thereof
HRP20220070T1 (hr) 2014-04-23 2022-04-01 Modernatx, Inc. Cjepiva nukleinske kiseline
US11364292B2 (en) 2015-07-21 2022-06-21 Modernatx, Inc. CHIKV RNA vaccines
EP3324979B1 (fr) 2015-07-21 2022-10-12 ModernaTX, Inc. Vaccins contre une maladie infectieuse
WO2017031232A1 (fr) 2015-08-17 2017-02-23 Modernatx, Inc. Procédés de préparation de particules et compositions associées
JP2018531290A (ja) 2015-10-22 2018-10-25 モデルナティーエックス, インコーポレイテッド 性感染症ワクチン
DK3718565T3 (da) 2015-10-22 2022-06-20 Modernatx Inc Vacciner mod respiratorisk virus
JP6921833B2 (ja) 2015-10-22 2021-08-18 モデルナティーエックス, インコーポレイテッド ヒトサイトメガロウイルスワクチン
WO2017070624A1 (fr) 2015-10-22 2017-04-27 Modernatx, Inc. Vaccins contre des maladies tropicales
JP6925688B2 (ja) 2015-10-22 2021-08-25 モデルナティーエックス, インコーポレイテッド 水痘帯状疱疹ウイルス(vzv)のための核酸ワクチン
SI3386484T1 (sl) 2015-12-10 2022-06-30 Modernatx, Inc. Sestave in metode za dovajanje terapevtskih sredstev
KR20230074598A (ko) 2016-05-18 2023-05-30 모더나티엑스, 인크. 릴랙신을 인코딩하는 폴리뉴클레오타이드
SG11201901941YA (en) 2016-09-14 2019-04-29 Modernatx Inc High purity rna compositions and methods for preparation thereof
JP6980780B2 (ja) 2016-10-21 2021-12-15 モデルナティーエックス, インコーポレイテッド ヒトサイトメガロウイルスワクチン
US10925958B2 (en) 2016-11-11 2021-02-23 Modernatx, Inc. Influenza vaccine
US11103578B2 (en) 2016-12-08 2021-08-31 Modernatx, Inc. Respiratory virus nucleic acid vaccines
US11384352B2 (en) 2016-12-13 2022-07-12 Modernatx, Inc. RNA affinity purification
EP3582790A4 (fr) 2017-02-16 2020-11-25 ModernaTX, Inc. Compositions immunogènes très puissantes
EP3609534A4 (fr) 2017-03-15 2021-01-13 ModernaTX, Inc. Vaccin à large spectre contre le virus de la grippe
WO2018170256A1 (fr) 2017-03-15 2018-09-20 Modernatx, Inc. Vaccin contre le virus de l'herpès simplex
WO2018170270A1 (fr) 2017-03-15 2018-09-20 Modernatx, Inc. Vaccin contre le virus varicelle-zona
WO2018170260A1 (fr) 2017-03-15 2018-09-20 Modernatx, Inc. Vaccin contre le virus respiratoire syncytial
WO2018170347A1 (fr) 2017-03-17 2018-09-20 Modernatx, Inc. Vaccins à base d'arn contre des maladies zoonotiques
US11905525B2 (en) 2017-04-05 2024-02-20 Modernatx, Inc. Reduction of elimination of immune responses to non-intravenous, e.g., subcutaneously administered therapeutic proteins
EP3638215A4 (fr) 2017-06-15 2021-03-24 Modernatx, Inc. Formulations d'arn
WO2019036683A1 (fr) 2017-08-18 2019-02-21 Modernatx, Inc. Procédés analytiques par hplc
MA49913A (fr) 2017-08-18 2021-05-05 Modernatx Inc Variants d'arn polymérase
WO2019036685A1 (fr) 2017-08-18 2019-02-21 Modernatx, Inc. Procédés pour analyse par clhp
AU2018326799A1 (en) 2017-08-31 2020-02-27 Modernatx, Inc. Methods of making lipid nanoparticles
EP3681514A4 (fr) 2017-09-14 2021-07-14 ModernaTX, Inc. Vaccins à arn contre le virus zika
EP3724355A1 (fr) * 2017-12-15 2020-10-21 Novartis AG Analyse de longueur de queue poly(a) d'arn par spectrométrie de masse
MA54676A (fr) 2018-01-29 2021-11-17 Modernatx Inc Vaccins à base d'arn contre le vrs
US11351242B1 (en) 2019-02-12 2022-06-07 Modernatx, Inc. HMPV/hPIV3 mRNA vaccine composition
CA3130888A1 (fr) 2019-02-20 2020-08-27 Modernatx, Inc. Variants d'arn polymerase pour le coiffage co-transcriptionnel
US11851694B1 (en) 2019-02-20 2023-12-26 Modernatx, Inc. High fidelity in vitro transcription
MX2022001664A (es) 2019-08-09 2022-07-19 Nutcracker Therapeutics Inc Aparato microfluídico y metodos de uso del mismo.
AU2020348860A1 (en) * 2019-09-19 2022-04-07 Modernatx, Inc. Cap guides and methods of use thereof for RNA mapping
JP2021185136A (ja) 2020-04-22 2021-12-09 ビオエンテッヒ・アールエヌエイ・ファーマシューティカルズ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング コロナウイルスワクチン
US11406703B2 (en) 2020-08-25 2022-08-09 Modernatx, Inc. Human cytomegalovirus vaccine
US11524023B2 (en) 2021-02-19 2022-12-13 Modernatx, Inc. Lipid nanoparticle compositions and methods of formulating the same
AU2022249357A1 (en) * 2021-04-01 2023-10-12 Modernatx, Inc. Methods for identification and ratio determination of rna species in multivalent rna compositions
US20230111049A1 (en) * 2021-10-08 2023-04-13 Waters Technologies Corporation Sample preparation for lc-ms based sequence mapping of nucleic acids
WO2024002985A1 (fr) 2022-06-26 2024-01-04 BioNTech SE Vaccin contre le coronavirus

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8911948B2 (en) * 2008-04-30 2014-12-16 Integrated Dna Technologies, Inc. RNase H-based assays utilizing modified RNA monomers
US10501512B2 (en) 2012-04-02 2019-12-10 Modernatx, Inc. Modified polynucleotides
US20160032273A1 (en) * 2013-03-15 2016-02-04 Moderna Therapeutics, Inc. Characterization of mrna molecules
WO2017031241A1 (fr) * 2015-08-17 2017-02-23 Modernatx, Inc. Cartographie/profilage de l'arn

Also Published As

Publication number Publication date
WO2018081462A1 (fr) 2018-05-03
US20180274009A1 (en) 2018-09-27
EP3532613A4 (fr) 2020-05-06
US20230212645A1 (en) 2023-07-06
EP3532613A1 (fr) 2019-09-04

Similar Documents

Publication Publication Date Title
MA46643A (fr) Méthodes et compositions pour le mappage d'arn
MA49421A (fr) Formulations d'arn
MA49913A (fr) Variants d'arn polymérase
MA46481A (fr) Compositions d'oligonucléotides et méthodes associées
MA49403A (fr) Compositions de pde5 et méthodes d'immunothérapie
MA44479A (fr) Arn transrepliquant
MA45188A (fr) Oligonucléotides, compositions et méthodes associées
MA50269A (fr) Compositions d'acides nucléiques-polypeptides et méthodes d'induction de saut d'exon
DK3804737T3 (da) Sammensætninger omfattende bakteriestammer
MA47680A (fr) Arn thérapeutique
MA50833A (fr) Compositions et méthodes pour l'édition génique pour l'hémophilie a
MA55629A (fr) Compositions d'anticorps pour le traitement de tumeurs
FR3016945B1 (fr) Plaque d'amortissement
EP3464313A4 (fr) Nucléotides modifiés 5 '-cyclo-phosphonate
MA46963A (fr) Méthodes pour déterminer le dosage de céllules car-t
MA45656A (fr) Nouveaux pyrimidine carboxamides utilisées comme inhibiteurs de l'enzyme vanin-1
MA43378A (fr) Compositions et méthodes pour la reduction de la réponse immunitaire contre récepteurs d'antigène chimériques
DK3600363T3 (da) Sammensætninger omfattende bakteriestammer
FR3016407B1 (fr) Boitier d'entrainement pour equipements
FR3022462B1 (fr) Composition orale d'anticorps anti-tnfalpha
MA54143A (fr) Compositions et méthodes
MA49006A (fr) Inhibiteurs d'ip6k
MA49576A (fr) Compositions et méthodes pour le traitement d'infections fongiques
MA43230A (fr) Méthodes et compositions pour le traitement d'une épidermolyse bulleuse
MA53831A (fr) Méthodes permettant de réduire l'agrégation d'anticorps bispécifiques