IL166599A0 - Crystalline solid form of (2s-5z)-2-amino-7-(ethanimidoylamino)-2-methylhept-5-enoic acid - Google Patents

Crystalline solid form of (2s-5z)-2-amino-7-(ethanimidoylamino)-2-methylhept-5-enoic acid

Info

Publication number
IL166599A0
IL166599A0 IL16659903A IL16659903A IL166599A0 IL 166599 A0 IL166599 A0 IL 166599A0 IL 16659903 A IL16659903 A IL 16659903A IL 16659903 A IL16659903 A IL 16659903A IL 166599 A0 IL166599 A0 IL 166599A0
Authority
IL
Israel
Prior art keywords
ethanimidoylamino
methylhept
amino
solid form
crystalline solid
Prior art date
Application number
IL16659903A
Other languages
English (en)
Original Assignee
Pharmacia Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia Corp filed Critical Pharmacia Corp
Publication of IL166599A0 publication Critical patent/IL166599A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C257/00—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines
    • C07C257/10—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines
    • C07C257/14—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines having carbon atoms of amidino groups bound to acyclic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
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    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
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    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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IL16659903A 2002-08-23 2003-08-22 Crystalline solid form of (2s-5z)-2-amino-7-(ethanimidoylamino)-2-methylhept-5-enoic acid IL166599A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US40552602P 2002-08-23 2002-08-23
PCT/US2003/026347 WO2004018412A1 (en) 2002-08-23 2003-08-22 Crystalline solid form of (2s-5z)-2-amino-7-(ethanimidoylamino)-2-methylhept-5-enoic acid

Publications (1)

Publication Number Publication Date
IL166599A0 true IL166599A0 (en) 2006-01-15

Family

ID=31946886

Family Applications (2)

Application Number Title Priority Date Filing Date
IL16659903A IL166599A0 (en) 2002-08-23 2003-08-22 Crystalline solid form of (2s-5z)-2-amino-7-(ethanimidoylamino)-2-methylhept-5-enoic acid
IL166599A IL166599A (en) 2002-08-23 2005-01-31 Crystalline solid form of (2s-5z) -2-amino-7-(ethanimidoylamino)-2-methylhept-5-enoic acid

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL166599A IL166599A (en) 2002-08-23 2005-01-31 Crystalline solid form of (2s-5z) -2-amino-7-(ethanimidoylamino)-2-methylhept-5-enoic acid

Country Status (21)

Country Link
US (1) US6998503B2 (xx)
EP (1) EP1534668B1 (xx)
JP (1) JP4708024B2 (xx)
KR (1) KR100893647B1 (xx)
CN (1) CN100588647C (xx)
AR (1) AR041038A1 (xx)
AT (1) ATE556047T1 (xx)
AU (1) AU2003258327B2 (xx)
BR (1) BR0313752A (xx)
CA (1) CA2494583C (xx)
ES (1) ES2384969T3 (xx)
HK (1) HK1078562A1 (xx)
IL (2) IL166599A0 (xx)
MX (1) MXPA05001708A (xx)
NO (1) NO20050609L (xx)
NZ (1) NZ538184A (xx)
PL (1) PL375557A1 (xx)
RU (1) RU2314290C2 (xx)
TW (1) TWI340133B (xx)
WO (1) WO2004018412A1 (xx)
ZA (1) ZA200501134B (xx)

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9127376D0 (en) 1991-12-24 1992-02-19 Wellcome Found Amidino derivatives
PT751930E (pt) 1994-03-24 2000-04-28 Searle & Co Derivados amidino uteis como inibidores da sintetase de oxido nitrico
US5684008A (en) 1994-11-09 1997-11-04 G. D. Searle & Co. Aminotetrazole derivatives useful as nitric oxide synthase inhibitors
US5945408A (en) 1996-03-06 1999-08-31 G.D. Searle & Co. Hydroxyanidino derivatives useful as nitric oxide synthase inhibitors
TWI290130B (en) * 2000-09-15 2007-11-21 Pharmacia Corp 2-Amino-2alkyl-5 heptenoic and heptynoic acid derivatives useful as nitric oxide synthase inhibitors
GB0031179D0 (en) * 2000-12-21 2001-01-31 Glaxo Group Ltd Nitric oxide synthase inhibitors
US7012098B2 (en) * 2001-03-23 2006-03-14 Pharmacia Corporation Inhibitors of inducible nitric oxide synthase for chemoprevention and treatment of cancers

Also Published As

Publication number Publication date
RU2314290C2 (ru) 2008-01-10
AU2003258327A1 (en) 2004-03-11
ES2384969T3 (es) 2012-07-16
KR20050058443A (ko) 2005-06-16
TWI340133B (en) 2011-04-11
CN1678572A (zh) 2005-10-05
WO2004018412A1 (en) 2004-03-04
NO20050609L (no) 2005-03-21
HK1078562A1 (en) 2006-03-17
KR100893647B1 (ko) 2009-04-17
JP4708024B2 (ja) 2011-06-22
ATE556047T1 (de) 2012-05-15
US6998503B2 (en) 2006-02-14
CN100588647C (zh) 2010-02-10
ZA200501134B (en) 2006-10-25
AR041038A1 (es) 2005-04-27
IL166599A (en) 2010-12-30
AU2003258327B2 (en) 2009-05-21
CA2494583C (en) 2010-02-02
CA2494583A1 (en) 2004-03-04
EP1534668A1 (en) 2005-06-01
JP2005536541A (ja) 2005-12-02
PL375557A1 (en) 2005-11-28
BR0313752A (pt) 2005-06-21
US20040132822A1 (en) 2004-07-08
NZ538184A (en) 2008-02-29
EP1534668B1 (en) 2012-05-02
TW200413291A (en) 2004-08-01
MXPA05001708A (es) 2005-04-19
RU2005104954A (ru) 2005-07-20

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