ATE556047T1 - Kristalline feste form der (2s-5z)-2-amino-7- - Google Patents

Kristalline feste form der (2s-5z)-2-amino-7-

Info

Publication number
ATE556047T1
ATE556047T1 AT03793292T AT03793292T ATE556047T1 AT E556047 T1 ATE556047 T1 AT E556047T1 AT 03793292 T AT03793292 T AT 03793292T AT 03793292 T AT03793292 T AT 03793292T AT E556047 T1 ATE556047 T1 AT E556047T1
Authority
AT
Austria
Prior art keywords
amino
solid form
crystalline solid
crystalline
solid
Prior art date
Application number
AT03793292T
Other languages
English (en)
Inventor
Ann HALLINAN
Original Assignee
Pharmacia Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia Corp filed Critical Pharmacia Corp
Application granted granted Critical
Publication of ATE556047T1 publication Critical patent/ATE556047T1/de

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C257/00Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines
    • C07C257/10Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines
    • C07C257/14Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines having carbon atoms of amidino groups bound to acyclic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/155Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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    • A61P1/12Antidiarrhoeals
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P1/14Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
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    • A61P1/18Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
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    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
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    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychiatry (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Dermatology (AREA)
  • Pulmonology (AREA)
  • Addiction (AREA)
  • Ophthalmology & Optometry (AREA)
  • Psychology (AREA)
  • Urology & Nephrology (AREA)
  • Hospice & Palliative Care (AREA)
  • Obesity (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Emergency Medicine (AREA)
  • Rheumatology (AREA)
  • Vascular Medicine (AREA)
  • Reproductive Health (AREA)
AT03793292T 2002-08-23 2003-08-22 Kristalline feste form der (2s-5z)-2-amino-7- ATE556047T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US40552602P 2002-08-23 2002-08-23
PCT/US2003/026347 WO2004018412A1 (en) 2002-08-23 2003-08-22 Crystalline solid form of (2s-5z)-2-amino-7-(ethanimidoylamino)-2-methylhept-5-enoic acid

Publications (1)

Publication Number Publication Date
ATE556047T1 true ATE556047T1 (de) 2012-05-15

Family

ID=31946886

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03793292T ATE556047T1 (de) 2002-08-23 2003-08-22 Kristalline feste form der (2s-5z)-2-amino-7-

Country Status (21)

Country Link
US (1) US6998503B2 (de)
EP (1) EP1534668B1 (de)
JP (1) JP4708024B2 (de)
KR (1) KR100893647B1 (de)
CN (1) CN100588647C (de)
AR (1) AR041038A1 (de)
AT (1) ATE556047T1 (de)
AU (1) AU2003258327B2 (de)
BR (1) BR0313752A (de)
CA (1) CA2494583C (de)
ES (1) ES2384969T3 (de)
HK (1) HK1078562A1 (de)
IL (2) IL166599A0 (de)
MX (1) MXPA05001708A (de)
NO (1) NO20050609L (de)
NZ (1) NZ538184A (de)
PL (1) PL375557A1 (de)
RU (1) RU2314290C2 (de)
TW (1) TWI340133B (de)
WO (1) WO2004018412A1 (de)
ZA (1) ZA200501134B (de)

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9127376D0 (en) 1991-12-24 1992-02-19 Wellcome Found Amidino derivatives
PT751930E (pt) 1994-03-24 2000-04-28 Searle & Co Derivados amidino uteis como inibidores da sintetase de oxido nitrico
US5684008A (en) 1994-11-09 1997-11-04 G. D. Searle & Co. Aminotetrazole derivatives useful as nitric oxide synthase inhibitors
US5945408A (en) 1996-03-06 1999-08-31 G.D. Searle & Co. Hydroxyanidino derivatives useful as nitric oxide synthase inhibitors
TWI290130B (en) * 2000-09-15 2007-11-21 Pharmacia Corp 2-Amino-2alkyl-5 heptenoic and heptynoic acid derivatives useful as nitric oxide synthase inhibitors
GB0031179D0 (en) * 2000-12-21 2001-01-31 Glaxo Group Ltd Nitric oxide synthase inhibitors
US7012098B2 (en) * 2001-03-23 2006-03-14 Pharmacia Corporation Inhibitors of inducible nitric oxide synthase for chemoprevention and treatment of cancers

Also Published As

Publication number Publication date
RU2314290C2 (ru) 2008-01-10
AU2003258327A1 (en) 2004-03-11
ES2384969T3 (es) 2012-07-16
KR20050058443A (ko) 2005-06-16
TWI340133B (en) 2011-04-11
CN1678572A (zh) 2005-10-05
WO2004018412A1 (en) 2004-03-04
NO20050609L (no) 2005-03-21
HK1078562A1 (en) 2006-03-17
KR100893647B1 (ko) 2009-04-17
JP4708024B2 (ja) 2011-06-22
US6998503B2 (en) 2006-02-14
CN100588647C (zh) 2010-02-10
ZA200501134B (en) 2006-10-25
AR041038A1 (es) 2005-04-27
IL166599A (en) 2010-12-30
AU2003258327B2 (en) 2009-05-21
CA2494583C (en) 2010-02-02
IL166599A0 (en) 2006-01-15
CA2494583A1 (en) 2004-03-04
EP1534668A1 (de) 2005-06-01
JP2005536541A (ja) 2005-12-02
PL375557A1 (en) 2005-11-28
BR0313752A (pt) 2005-06-21
US20040132822A1 (en) 2004-07-08
NZ538184A (en) 2008-02-29
EP1534668B1 (de) 2012-05-02
TW200413291A (en) 2004-08-01
MXPA05001708A (es) 2005-04-19
RU2005104954A (ru) 2005-07-20

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