ZW4889A1 - Piperidine compounds and their preparation and use t - Google Patents
Piperidine compounds and their preparation and use tInfo
- Publication number
- ZW4889A1 ZW4889A1 ZW48/89A ZW4889A ZW4889A1 ZW 4889 A1 ZW4889 A1 ZW 4889A1 ZW 48/89 A ZW48/89 A ZW 48/89A ZW 4889 A ZW4889 A ZW 4889A ZW 4889 A1 ZW4889 A1 ZW 4889A1
- Authority
- ZW
- Zimbabwe
- Prior art keywords
- alkoxy
- alkyl
- cyano
- aryl
- halogen
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
- C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Endocrinology (AREA)
- Rheumatology (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Cephalosporin Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DK231088A DK231088D0 (da) | 1988-04-28 | 1988-04-28 | Piperidinforbindelser, deres fremstilling og anvendelse |
Publications (1)
Publication Number | Publication Date |
---|---|
ZW4889A1 true ZW4889A1 (en) | 1989-08-09 |
Family
ID=8111522
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZW48/89A ZW4889A1 (en) | 1988-04-28 | 1989-04-12 | Piperidine compounds and their preparation and use t |
Country Status (17)
Country | Link |
---|---|
EP (1) | EP0339579B1 (fr) |
JP (1) | JP2857414B2 (fr) |
KR (1) | KR900016175A (fr) |
CN (1) | CN1037332A (fr) |
AT (1) | ATE168375T1 (fr) |
AU (1) | AU631121B2 (fr) |
DE (1) | DE68928735T2 (fr) |
DK (1) | DK231088D0 (fr) |
ES (1) | ES2118708T3 (fr) |
FI (1) | FI92822C (fr) |
HU (1) | HUT55387A (fr) |
IL (1) | IL89903A0 (fr) |
NO (1) | NO173826C (fr) |
NZ (1) | NZ228895A (fr) |
PT (1) | PT90412B (fr) |
ZA (1) | ZA893003B (fr) |
ZW (1) | ZW4889A1 (fr) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK640289D0 (da) * | 1989-12-18 | 1989-12-18 | Ferrosan As | Ny heterocyklisk kemi |
IL98757A (en) * | 1990-07-18 | 1997-01-10 | Novo Nordisk As | Piperidine derivatives their preparation and pharmaceutical compositions containing them |
GB9226111D0 (en) * | 1992-12-15 | 1993-02-10 | Smithkline Beecham Plc | Madicaments |
US6197833B1 (en) | 1995-07-24 | 2001-03-06 | Apollo Biopharmaceutics, Inc. | Neuroprotective effects of polycyclic phenolic compounds |
US6319914B1 (en) | 1993-11-05 | 2001-11-20 | Apollo Biopharmaceuticals, Inc. | Cytoprotective effect of polycyclic phenolic compounds |
US5859001A (en) * | 1996-01-11 | 1999-01-12 | University Of Florida Research Foundation, Inc. | Neuroprotective effects of polycyclic phenolic compounds |
ES2102295B1 (es) * | 1994-03-18 | 1998-04-01 | Ferrer Int | Nuevos compuestos derivados de la n-benzoilmetil-piperidina. |
KR100502229B1 (ko) * | 1995-02-28 | 2005-11-08 | 다이이찌 산토리 파마 가부시키가이샤 | 아릴피페리딘및아릴피페라진유도체,및이를함유하는약제 |
WO1997003661A1 (fr) * | 1995-07-24 | 1997-02-06 | University Of Florida Research Foundation, Incorporated | Utilisation de composes phenoliques polycycliques non ×strogeniques pour la fabrication d'un medicament visant a conferer une neuroprotection cellulaire |
ES2117557B1 (es) * | 1996-02-29 | 1999-07-01 | Ferrer Int | Nuevo procedimiento de obtencion de (-)-trans -n-p-fluorobenzoilmetil-4-(p-fluorofenil)-3- ((3,4-(metilendioxi)fenoxi ) metil)-piperidina. |
WO1998003172A1 (fr) * | 1996-07-22 | 1998-01-29 | Suntory Limited | Derives arylpiperidinol et arylpiperidine et medicaments les contenant |
AU710594B2 (en) | 1996-07-22 | 1999-09-23 | Asubio Pharma Co., Ltd. | Arylpiperidinol and arylpiperidine derivatives and pharmaceuticals containing the same |
ES2329739T3 (es) | 1997-04-07 | 2009-11-30 | Georgetown University | Analogos de cocaina. |
US6376672B1 (en) * | 1999-04-27 | 2002-04-23 | Hoffmann-La Roche Inc. | Naphthalenylmethoxypiperidines as renin inhibitors |
AU1018801A (en) * | 1999-10-29 | 2001-05-14 | Novo Nordisk A/S | Use of 3,4-substituted piperidines |
WO2004043921A1 (fr) * | 2002-11-11 | 2004-05-27 | Natco Pharma Limited | Nouveau procede de preparation de 4-aryl-3-hydroxymethyl-1-methylpiperidines |
US20070142389A1 (en) * | 2005-12-20 | 2007-06-21 | Pfizer Inc. | Piperidine derivatives |
HUE058819T2 (hu) * | 2015-09-02 | 2022-09-28 | Trevena Inc | 6-tagú aza-heterociklusos delta-opioid receptort moduláló vegyületek, felhasználásuk és elõállításuk módszerei |
EP3582779B1 (fr) | 2017-02-17 | 2024-04-17 | Trevena, Inc. | Composés modulateurs du récepteur delta des opioïdes contenant des aza-hétérocycles à 5 chaînons, leurs procédés d'utilisation et de fabrication |
BR112019016775A2 (pt) | 2017-02-17 | 2020-03-31 | Trevena, Inc. | Compostos moduladores de receptor delta-opioide contendo aza-heterocíclico com 7 membros, métodos de uso e produção dos mesmos |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1422263A (en) * | 1973-01-30 | 1976-01-21 | Ferrosan As | 4-phenyl-piperidine compounds |
EP0190496A3 (fr) * | 1984-12-13 | 1987-05-27 | Beecham Group Plc | Dérivés de la pipéridine à activité gastro-intestinale |
EP0223403B1 (fr) * | 1985-10-25 | 1993-08-04 | Beecham Group Plc | Dérivé de pipéridine, sa préparation et son utilisation comme médicament |
IE66332B1 (en) * | 1986-11-03 | 1995-12-27 | Novo Nordisk As | Piperidine compounds and their preparation and use |
-
1988
- 1988-04-28 DK DK231088A patent/DK231088D0/da not_active Application Discontinuation
-
1989
- 1989-04-10 IL IL89903A patent/IL89903A0/xx not_active IP Right Cessation
- 1989-04-12 ZW ZW48/89A patent/ZW4889A1/xx unknown
- 1989-04-24 AU AU33366/89A patent/AU631121B2/en not_active Ceased
- 1989-04-24 ZA ZA893003A patent/ZA893003B/xx unknown
- 1989-04-25 DE DE68928735T patent/DE68928735T2/de not_active Expired - Fee Related
- 1989-04-25 AT AT89107481T patent/ATE168375T1/de active
- 1989-04-25 ES ES89107481T patent/ES2118708T3/es not_active Expired - Lifetime
- 1989-04-25 EP EP89107481A patent/EP0339579B1/fr not_active Expired - Lifetime
- 1989-04-26 NZ NZ228895A patent/NZ228895A/en unknown
- 1989-04-27 NO NO891762A patent/NO173826C/no unknown
- 1989-04-27 FI FI892012A patent/FI92822C/fi not_active IP Right Cessation
- 1989-04-27 HU HU892019A patent/HUT55387A/hu unknown
- 1989-04-28 KR KR1019890005606A patent/KR900016175A/ko not_active Application Discontinuation
- 1989-04-28 PT PT90412A patent/PT90412B/pt not_active IP Right Cessation
- 1989-04-28 CN CN89102923A patent/CN1037332A/zh active Pending
- 1989-04-28 JP JP1107889A patent/JP2857414B2/ja not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
AU3336689A (en) | 1989-11-02 |
EP0339579B1 (fr) | 1998-07-15 |
NO891762L (no) | 1989-10-30 |
DK231088D0 (da) | 1988-04-28 |
KR900016175A (ko) | 1990-11-12 |
HUT55387A (en) | 1991-05-28 |
DE68928735T2 (de) | 1998-11-19 |
ES2118708T3 (es) | 1998-10-01 |
JPH01313461A (ja) | 1989-12-18 |
NO173826B (no) | 1993-11-01 |
AU631121B2 (en) | 1992-11-19 |
NO891762D0 (no) | 1989-04-27 |
ATE168375T1 (de) | 1998-08-15 |
EP0339579A3 (fr) | 1991-12-18 |
EP0339579A2 (fr) | 1989-11-02 |
ZA893003B (en) | 1989-12-27 |
JP2857414B2 (ja) | 1999-02-17 |
DE68928735D1 (de) | 1998-08-20 |
CN1037332A (zh) | 1989-11-22 |
FI92822C (fi) | 1995-01-10 |
NZ228895A (en) | 1992-05-26 |
IL89903A0 (en) | 1989-12-15 |
FI92822B (fi) | 1994-09-30 |
FI892012A0 (fi) | 1989-04-27 |
NO173826C (no) | 1994-02-09 |
PT90412B (pt) | 1994-09-30 |
FI892012A (fi) | 1989-10-29 |
PT90412A (pt) | 1989-11-10 |
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