ZA989999B - New process for the preparation of 5-methoxy-2-(((4-methoxy-3,5-dimethyl-2-pyridinyl)methyl)sulfinyl)1H-benzimidazole - Google Patents

New process for the preparation of 5-methoxy-2-(((4-methoxy-3,5-dimethyl-2-pyridinyl)methyl)sulfinyl)1H-benzimidazole

Info

Publication number
ZA989999B
ZA989999B ZA989999A ZA989999A ZA989999B ZA 989999 B ZA989999 B ZA 989999B ZA 989999 A ZA989999 A ZA 989999A ZA 989999 A ZA989999 A ZA 989999A ZA 989999 B ZA989999 B ZA 989999B
Authority
ZA
South Africa
Prior art keywords
methoxy
sulfinyl
benzimidazole
pyridinyl
dimethyl
Prior art date
Application number
ZA989999A
Other languages
English (en)
Inventor
Hanna Cotton
Magnus Larsson
Anders Mattson
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Ab filed Critical Astra Ab
Publication of ZA989999B publication Critical patent/ZA989999B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Electrical Discharge Machining, Electrochemical Machining, And Combined Machining (AREA)
ZA989999A 1997-11-14 1998-11-02 New process for the preparation of 5-methoxy-2-(((4-methoxy-3,5-dimethyl-2-pyridinyl)methyl)sulfinyl)1H-benzimidazole ZA989999B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9704183A SE9704183D0 (sv) 1997-11-14 1997-11-14 New process

Publications (1)

Publication Number Publication Date
ZA989999B true ZA989999B (en) 1999-06-17

Family

ID=20408989

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA989999A ZA989999B (en) 1997-11-14 1998-11-02 New process for the preparation of 5-methoxy-2-(((4-methoxy-3,5-dimethyl-2-pyridinyl)methyl)sulfinyl)1H-benzimidazole

Country Status (35)

Country Link
US (1) US6303788B1 (ko)
EP (1) EP0964859A1 (ko)
JP (1) JP2001508466A (ko)
KR (1) KR20000070069A (ko)
CN (1) CN1145624C (ko)
AR (1) AR013740A1 (ko)
AU (1) AU750743B2 (ko)
BR (1) BR9806871A (ko)
CA (1) CA2276753A1 (ko)
DE (1) DE964859T1 (ko)
DZ (1) DZ2641A1 (ko)
EE (1) EE04154B1 (ko)
ES (1) ES2138950T1 (ko)
GR (1) GR990300046T1 (ko)
HR (1) HRP990218A2 (ko)
HU (1) HUP0003737A3 (ko)
ID (1) ID21999A (ko)
IL (1) IL130647A0 (ko)
IN (1) IN190801B (ko)
IS (1) IS5106A (ko)
MA (1) MA26564A1 (ko)
MY (1) MY118199A (ko)
NO (1) NO318197B1 (ko)
NZ (1) NZ336447A (ko)
PL (1) PL334701A1 (ko)
RU (1) RU2211218C2 (ko)
SE (1) SE9704183D0 (ko)
SK (1) SK87299A3 (ko)
TN (1) TNSN98202A1 (ko)
TR (1) TR199901643T1 (ko)
TW (1) TW588046B (ko)
UA (1) UA68342C2 (ko)
WO (1) WO1999025711A1 (ko)
YU (1) YU31199A (ko)
ZA (1) ZA989999B (ko)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9301830D0 (sv) * 1993-05-28 1993-05-28 Ab Astra New compounds
US5840737A (en) 1996-01-04 1998-11-24 The Curators Of The University Of Missouri Omeprazole solution and method for using same
US6489346B1 (en) 1996-01-04 2002-12-03 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
IL142703A (en) 1998-11-10 2006-04-10 Astrazeneca Ab Crystalline form of omeprazole
UA72748C2 (en) 1998-11-10 2005-04-15 Astrazeneca Ab A novel crystalline form of omeprazole
CN1781918A (zh) * 2001-02-02 2006-06-07 特瓦制药工业有限公司 制备硫酯化合物的方法
SE0203092D0 (en) * 2002-10-18 2002-10-18 Astrazeneca Ab Method for the synthesis of a benzimidazole compound
US8993599B2 (en) 2003-07-18 2015-03-31 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
US8906940B2 (en) 2004-05-25 2014-12-09 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
US7915422B2 (en) 2004-10-11 2011-03-29 Ranbaxy Laboratories Limited Processes for the preparation of substituted sulfoxides
EP1801110A1 (en) 2005-12-22 2007-06-27 KRKA, tovarna zdravil, d.d., Novo mesto Esomeprazole arginine salt
CN1810803B (zh) * 2006-02-17 2010-11-17 中国科学院上海有机化学研究所 高对映体选择性制备(s)-奥美拉唑的方法
CN101538264A (zh) * 2008-03-19 2009-09-23 中国科学院成都有机化学有限公司 手性亚砜类化合物的制备新方法
CN102603621B (zh) * 2012-02-07 2013-09-04 成都苑东药业有限公司 一种新型手性亚砜化合物和以该化合物制备埃索美拉唑钠的方法
CN106083819A (zh) * 2016-06-08 2016-11-09 扬子江药业集团有限公司 一种奥美拉唑的制备方法
ES2948511A1 (es) * 2021-09-08 2023-09-13 Fundacion Para La Investigacion Biomedica Del Hospital Univ De La Princesa Derivados de n-sulfonilureas y su uso terapeutico

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE7804231L (sv) 1978-04-14 1979-10-15 Haessle Ab Magsyrasekretionsmedel
SE9002043D0 (sv) 1990-06-07 1990-06-07 Astra Ab Improved method for synthesis
NZ244301A (en) 1991-09-20 1994-08-26 Merck & Co Inc Preparation of 2-pyridylmethylsulphinylbenzimidazole and pyridoimidazole derivatives from the corresponding sulphenyl compounds
SE504459C2 (sv) * 1994-07-15 1997-02-17 Astra Ab Förfarande för framställning av substituerade sulfoxider

Also Published As

Publication number Publication date
AR013740A1 (es) 2001-01-10
ES2138950T1 (es) 2000-02-01
SK87299A3 (en) 2000-02-14
EE9900391A (et) 2000-04-17
KR20000070069A (ko) 2000-11-25
HUP0003737A2 (hu) 2001-10-28
JP2001508466A (ja) 2001-06-26
IL130647A0 (en) 2000-06-01
DZ2641A1 (fr) 2003-03-15
NO993298D0 (no) 1999-07-02
US6303788B1 (en) 2001-10-16
CN1145624C (zh) 2004-04-14
PL334701A1 (en) 2000-03-13
HRP990218A2 (en) 2000-08-31
MY118199A (en) 2004-09-30
CN1243512A (zh) 2000-02-02
IN190801B (ko) 2003-08-23
DE964859T1 (de) 2000-05-04
AU750743B2 (en) 2002-07-25
NO993298L (no) 1999-07-02
CA2276753A1 (en) 1999-05-27
EP0964859A1 (en) 1999-12-22
AU1058299A (en) 1999-06-07
TW588046B (en) 2004-05-21
TNSN98202A1 (fr) 2005-03-15
NZ336447A (en) 2001-02-23
IS5106A (is) 1999-07-02
BR9806871A (pt) 2000-04-18
TR199901643T1 (xx) 2000-01-21
HUP0003737A3 (en) 2002-01-28
YU31199A (sh) 2002-06-19
UA68342C2 (en) 2004-08-16
ID21999A (id) 1999-08-19
RU2211218C2 (ru) 2003-08-27
EE04154B1 (et) 2003-10-15
MA26564A1 (fr) 2004-12-20
GR990300046T1 (en) 2000-07-31
WO1999025711A1 (en) 1999-05-27
NO318197B1 (no) 2005-02-14
SE9704183D0 (sv) 1997-11-14

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