ZA989450B - Novel use of compounds for anti-pruritic activity - Google Patents

Novel use of compounds for anti-pruritic activity

Info

Publication number
ZA989450B
ZA989450B ZA989450A ZA989450A ZA989450B ZA 989450 B ZA989450 B ZA 989450B ZA 989450 A ZA989450 A ZA 989450A ZA 989450 A ZA989450 A ZA 989450A ZA 989450 B ZA989450 B ZA 989450B
Authority
ZA
South Africa
Prior art keywords
compounds
novel use
pruritic activity
pruritic
activity
Prior art date
Application number
ZA989450A
Other languages
English (en)
Inventor
Don E Griswold
Siegfried B Christensen Iv
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Publication of ZA989450B publication Critical patent/ZA989450B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/04—Antipruritics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ZA989450A 1997-10-17 1998-10-16 Novel use of compounds for anti-pruritic activity ZA989450B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US6374697P 1997-10-17 1997-10-17

Publications (1)

Publication Number Publication Date
ZA989450B true ZA989450B (en) 1999-04-19

Family

ID=22051225

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA989450A ZA989450B (en) 1997-10-17 1998-10-16 Novel use of compounds for anti-pruritic activity

Country Status (18)

Country Link
EP (1) EP1030666A4 (tr)
JP (1) JP2001520196A (tr)
KR (1) KR20010031149A (tr)
CN (1) CN1306426A (tr)
AR (1) AR015966A1 (tr)
AU (1) AU740875B2 (tr)
BR (1) BR9814080A (tr)
CA (1) CA2306985A1 (tr)
CO (1) CO4810374A1 (tr)
CZ (1) CZ20001376A3 (tr)
HU (1) HUP0003792A3 (tr)
IL (1) IL135581A0 (tr)
NO (1) NO20001847L (tr)
NZ (1) NZ503551A (tr)
PL (1) PL341062A1 (tr)
TR (1) TR200001040T2 (tr)
WO (1) WO1999020280A1 (tr)
ZA (1) ZA989450B (tr)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60113731T2 (de) 2001-01-31 2006-06-29 Pfizer Products Inc., Groton Als inhibitoren von pde4-isozymen geeignete etherderivate
US7250518B2 (en) 2001-01-31 2007-07-31 Pfizer Inc. Nicotinamide acids, amides, and their mimetics active as inhibitors of PDE4 isozymes
KR20030072614A (ko) 2001-01-31 2003-09-15 화이자 프로덕츠 인크. Ｐｄｅ４ 이소자임 억제제로 유용한 티아졸릴-,옥사졸릴-, 피롤릴- 및 이미다졸릴-산 아미드 유도체
CA2436535A1 (en) 2001-01-31 2002-08-08 Prizer Products Inc. Nicotinamide biaryl derivatives useful as inhibitors of pde4 isozymes
US20030175314A1 (en) * 2001-11-19 2003-09-18 Didriksen Erik Johannes Pharmaceutical composition for dermal application
US20060258703A1 (en) * 2003-07-17 2006-11-16 Ono Pharmaceutical Co., Ltd. Remedy for pruritus comprising piperidine derivative as the active ingredient
WO2005053672A1 (ja) * 2003-12-04 2005-06-16 Santen Pharmaceutical Co., Ltd. シロミラストまたはその塩を有効成分とする掻痒治療剤
JP2005187458A (ja) * 2003-12-04 2005-07-14 Santen Pharmaceut Co Ltd シロミラストまたはその塩を有効成分とする掻痒治療剤
JP5001012B2 (ja) 2004-02-14 2012-08-15 グラクソスミスクライン・リミテッド・ライアビリティ・カンパニー Ｈｍ７４ａ受容体活性を有する薬剤
JP2008137892A (ja) * 2005-03-04 2008-06-19 Eisai Co Ltd 止痒剤
EP2272848B1 (en) 2005-08-10 2012-12-26 Glaxosmithkline LLC Xanthine derivatives as selective HM74A agonists
TWI404709B (zh) * 2006-02-21 2013-08-11 Eisai R&D Man Co Ltd 4- (3-benzamidophenyl) -6,7-dimethoxy-2-methylamine quinazoline derivatives
AU2007218725B2 (en) * 2006-02-21 2011-12-01 Eisai R & D Management Co., Ltd. 4-(3-benzoylaminophenyl)-6,7-dimethoxy-2- methylaminoquinazoline derivative
CA2678477A1 (en) 2007-02-16 2008-08-21 Eisai R&D Management Co., Ltd. Crystal, amorphous form and salt of methyl n-[3-(6,7-dimethoxy-2-methylaminoquinazolin-4-yl)phenyl]terephthalamic acid
EP2202229B1 (en) 2007-08-17 2012-03-14 Eisai R&D Management Co., Ltd. Novel preparation for external use
ATE538102T1 (de) 2007-08-17 2012-01-15 Eisai R&D Man Co Ltd Verfahren zur herstellung eines chinazolinderivats
ES2659458T3 (es) 2011-06-28 2018-03-15 Mitsubishi Tanabe Pharma Corporation Compuestos de naftaleno para tratar el prurito
WO2016119570A1 (zh) 2015-01-30 2016-08-04 上海珊顿医药科技有限公司 尿酸性或痛风性疾病的预防或治疗

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2098846A1 (en) * 1990-12-21 1992-06-22 David G. Smith Xanthine derivatives
SI0889886T1 (en) * 1996-03-26 2003-02-28 Altana Pharma Ag Novel phenanthridines substituted in the 6 position
PT912568E (pt) * 1996-05-15 2003-04-30 Altana Pharma Ag Imidazopiridinas
SI0968211T1 (en) * 1997-03-07 2004-02-29 Altana Pharma Ag Tetrazole derivatives
SK122199A3 (en) * 1997-03-18 2000-12-11 Basf Ag Methods and compositions for modulating responsiveness to corticosteroids
DK0988302T3 (da) * 1997-06-03 2003-06-02 Altana Pharma Ag Benzonaphthyridiner

Also Published As

Publication number Publication date
HUP0003792A2 (hu) 2001-10-28
NO20001847D0 (no) 2000-04-10
IL135581A0 (en) 2001-05-20
JP2001520196A (ja) 2001-10-30
NO20001847L (no) 2000-04-10
EP1030666A1 (en) 2000-08-30
NZ503551A (en) 2002-05-31
PL341062A1 (en) 2001-03-26
KR20010031149A (ko) 2001-04-16
AU1093899A (en) 1999-05-10
EP1030666A4 (en) 2002-10-16
CO4810374A1 (es) 1999-06-30
AR015966A1 (es) 2001-05-30
TR200001040T2 (tr) 2001-01-22
BR9814080A (pt) 2000-09-26
WO1999020280A1 (en) 1999-04-29
CA2306985A1 (en) 1999-04-29
HUP0003792A3 (en) 2001-12-28
CN1306426A (zh) 2001-08-01
CZ20001376A3 (cs) 2002-06-12
AU740875B2 (en) 2001-11-15

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