ZA988754B - An enzymatic process for preparing 7beta- (4-carboxy-butanamido) cephalosporanic acid using the modified D-amino acid oxydase enzyme from trigonopsis variabilis produced in escherichia coli - Google Patents

An enzymatic process for preparing 7beta- (4-carboxy-butanamido) cephalosporanic acid using the modified D-amino acid oxydase enzyme from trigonopsis variabilis produced in escherichia coli

Info

Publication number
ZA988754B
ZA988754B ZA988754A ZA988754A ZA988754B ZA 988754 B ZA988754 B ZA 988754B ZA 988754 A ZA988754 A ZA 988754A ZA 988754 A ZA988754 A ZA 988754A ZA 988754 B ZA988754 B ZA 988754B
Authority
ZA
South Africa
Prior art keywords
butanamido
carboxy
modified
produced
escherichia coli
Prior art date
Application number
ZA988754A
Other languages
English (en)
Inventor
Jose Luis Garcia Lopez
Estrella Cortes Rubio
Jorge Alonso Palacios
Encarnacion Mellado Duran
Bruno Diez Garcia
Jose Manuel Guisan Seijas
Francisco Salto Maldonado
Jose Luis Barredo Fuente
Original Assignee
Antibioticos Sau
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Antibioticos Sau filed Critical Antibioticos Sau
Publication of ZA988754B publication Critical patent/ZA988754B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
    • C12N9/0014—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4)
    • C12N9/0022—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4) with oxygen as acceptor (1.4.3)
    • C12N9/0024—D-Amino acid oxidase (1.4.3.3)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P35/00—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin
    • C12P35/06—Cephalosporin C; Derivatives thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
ZA988754A 1997-09-25 1998-09-23 An enzymatic process for preparing 7beta- (4-carboxy-butanamido) cephalosporanic acid using the modified D-amino acid oxydase enzyme from trigonopsis variabilis produced in escherichia coli ZA988754B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES009702008A ES2131018B1 (es) 1997-09-25 1997-09-25 Un procedimiento enzimatico para preparar acido 7beta-(4-carboxibutanamido)cefalosporanico utilizando la enzima d-aminoacido oxidasa de trigonopsis variabilis modificada producida en escherichia coli.

Publications (1)

Publication Number Publication Date
ZA988754B true ZA988754B (en) 1999-06-28

Family

ID=8300695

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA988754A ZA988754B (en) 1997-09-25 1998-09-23 An enzymatic process for preparing 7beta- (4-carboxy-butanamido) cephalosporanic acid using the modified D-amino acid oxydase enzyme from trigonopsis variabilis produced in escherichia coli

Country Status (17)

Country Link
US (1) US6635458B2 (zh)
EP (1) EP0969088A1 (zh)
JP (1) JP2001506868A (zh)
KR (1) KR20000069110A (zh)
CN (1) CN1246147A (zh)
AU (1) AU9162898A (zh)
CA (1) CA2272354A1 (zh)
CZ (1) CZ182399A3 (zh)
EE (1) EE9900205A (zh)
ES (1) ES2131018B1 (zh)
HU (1) HUP0000797A2 (zh)
IL (1) IL129533A0 (zh)
LT (1) LT4628B (zh)
LV (1) LV12359B (zh)
SK (1) SK64899A3 (zh)
WO (1) WO1999015632A1 (zh)
ZA (1) ZA988754B (zh)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100342014C (zh) * 2004-04-08 2007-10-10 百瑞全球有限公司 重组d－氨基酸氧化酶
CN1912130B (zh) * 2005-08-08 2011-06-15 百瑞全球有限公司 一种用于制备7-氨基头孢霉烷酸的两步酶法
CN101016540B (zh) * 2006-02-10 2010-04-07 台湾尖端先进生技医药股份有限公司 C-端含有组氨酸标记的hoxb4重组蛋白质的制造方法及用途

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2268022B1 (zh) * 1974-04-22 1977-06-24 Rhone Poulenc Ind
JPS62262994A (ja) * 1986-05-12 1987-11-16 Asahi Chem Ind Co Ltd Ｄ−アミノ酸オキシダ−ゼ遺伝子
CA1340522C (en) * 1987-03-10 1999-05-04 Heinz Dobeli Fusion proteins containing neighbouring histidines for improved purification
CA2100987C (en) 1992-07-27 1999-06-15 Kaoru Furuya A transformant capable of producing d-amino acid oxidase
US5397653A (en) 1993-04-30 1995-03-14 Westinghouse Electric Corporation Filler wire composition and method of welding turbine component with filter wire composition and its product thereof
ES2109194B1 (es) 1996-04-22 1998-07-16 Antibioticos Sa Un procedimiento para producir la enzima d-aminoacido oxidasa de rhodotorula gracilis en celulas hospedantes.

Also Published As

Publication number Publication date
CN1246147A (zh) 2000-03-01
LT99051A (en) 1999-10-25
US6635458B2 (en) 2003-10-21
LT4628B (lt) 2000-02-25
CZ182399A3 (cs) 1999-09-15
HUP0000797A2 (en) 2000-07-28
ES2131018A1 (es) 1999-07-01
WO1999015632A1 (es) 1999-04-01
ES2131018B1 (es) 2000-04-01
KR20000069110A (ko) 2000-11-25
IL129533A0 (en) 2000-02-29
SK64899A3 (en) 2000-05-16
LV12359A (lv) 1999-10-20
CA2272354A1 (en) 1999-04-01
JP2001506868A (ja) 2001-05-29
US20030119087A1 (en) 2003-06-26
AU9162898A (en) 1999-04-12
LV12359B (en) 2000-03-20
EE9900205A (et) 1999-12-15
EP0969088A1 (en) 2000-01-05

Similar Documents

Publication Publication Date Title
AU7535491A (en) Cephalosporin acetylhydrolase gene and protein encoded by said gene
ZA972439B (en) Amino acid fermentation processes.
EP0456107A3 (en) Process for the enzymatic reduction of oxo-compounds, especially acetophenone and the enzyme therefor
WO1997018234A3 (en) Extraction of proteins into carbon dioxide
AU3026399A (en) An enzymatic oil-degumming process
ZA98496B (en) Process for the production of acetic acid.
EP0678576A3 (en) Fructosyl amino acid oxidase and process for its preparation.
EP0842937A3 (en) Process for the preparation of the cephalosporin derivatives cefotaxime and ceftriaxone
AU6645294A (en) L-amino acid oxidase
AU642688B2 (en) Novel glucose isomerases with an altered PH optimum
GB2323361A (en) Improved process for the production of semi-synthetic cephalosporins via expandase activity on penicillin G
ZA988754B (en) An enzymatic process for preparing 7beta- (4-carboxy-butanamido) cephalosporanic acid using the modified D-amino acid oxydase enzyme from trigonopsis variabilis produced in escherichia coli
OA09873A (en) Process for preparing optically active cyanohydrins with enzymes.
AU9560198A (en) Process for the preparation of a beta-lactam antibiotic
AU3167497A (en) Enzymatic processes for preparing (s)-cyanohydrins
AU9257998A (en) Method for enhancing the activity of an enzyme
AU3256097A (en) Enzymatic esterification process
AU5364390A (en) Method for the production of amidase enzyme
IL133259A0 (en) D-amino acid oxidase promoter from trigonopsis variabilis
AU2389097A (en) Process for producing the enzyme d-aminoacido oxydase of (rhodotorula gracilis) in host cells
HK1052029A1 (en) Method for increasing the yield of recombinant proteins in microbial fermentation processes.
AU6833398A (en) Process for the inactivation of genes which code for enzymes for the catabolism of phenyl acetate, plasmids involved in such process and strains transformed t herewith
EP0638649A3 (en) New use of alcaligenes faecalis penicillin G acylase
ZA996751B (en) Process for the fermentative production of L-amino acids.
AU3099795A (en) Enzyme from microbial source: phthalyl amidase