ZA986390B - Piperazine derivatives - Google Patents

Piperazine derivatives

Info

Publication number
ZA986390B
ZA986390B ZA986390A ZA986390A ZA986390B ZA 986390 B ZA986390 B ZA 986390B ZA 986390 A ZA986390 A ZA 986390A ZA 986390 A ZA986390 A ZA 986390A ZA 986390 B ZA986390 B ZA 986390B
Authority
ZA
South Africa
Prior art keywords
piperazine derivatives
piperazine
derivatives
Prior art date
Application number
ZA986390A
Other languages
English (en)
Inventor
Henning Boettcher
Gerd Bartoszyk
Hartmut Greiner
Christoph Seyfried
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of ZA986390B publication Critical patent/ZA986390B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA986390A 1997-07-18 1998-07-17 Piperazine derivatives ZA986390B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19730989A DE19730989A1 (de) 1997-07-18 1997-07-18 Piperazin-Derivate

Publications (1)

Publication Number Publication Date
ZA986390B true ZA986390B (en) 1999-05-24

Family

ID=7836208

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA986390A ZA986390B (en) 1997-07-18 1998-07-17 Piperazine derivatives

Country Status (23)

Country Link
US (1) US6251908B1 (hu)
EP (1) EP0998474B1 (hu)
JP (1) JP2001510193A (hu)
KR (1) KR100528684B1 (hu)
CN (1) CN1093127C (hu)
AR (1) AR010932A1 (hu)
AT (1) ATE353326T1 (hu)
AU (1) AU731332B2 (hu)
BR (1) BR9810607A (hu)
CA (1) CA2296687A1 (hu)
DE (2) DE19730989A1 (hu)
ES (1) ES2281131T3 (hu)
HU (1) HUP0002718A3 (hu)
ID (1) ID24663A (hu)
MY (1) MY132794A (hu)
NO (1) NO20000216D0 (hu)
PL (1) PL191078B1 (hu)
RU (1) RU2194048C2 (hu)
SK (1) SK352000A3 (hu)
TW (1) TW425398B (hu)
UA (1) UA59407C2 (hu)
WO (1) WO1999003855A1 (hu)
ZA (1) ZA986390B (hu)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SK287018B6 (sk) * 1999-08-23 2009-09-07 Solvay Pharmaceuticals B. V. Deriváty fenylpiperazínov, spôsob ich prípravy, farmaceutická kompozícia s ich obsahom a ich použitie
AU1502702A (en) * 2000-11-14 2002-05-27 Merck Patent Gmbh Novel uses of combined 5-HT<sub>1A</sub> agonists and serotonin reuptake inhibitors
AR032712A1 (es) * 2001-02-21 2003-11-19 Solvay Pharm Bv Un mesilato de derivados de fenilpiperazina y composiciones farmaceuticas que lo contienen
DE10112151A1 (de) * 2001-03-14 2002-09-19 Merck Patent Gmbh Substituierte Benzofuran-2-carbonsäureamide
ATE424825T1 (de) 2001-07-20 2009-03-15 Psychogenics Inc Behandlung von hyperaktivitätsstörungen und aufmerksamkeitsdefiziten
US20030045449A1 (en) * 2001-08-15 2003-03-06 Pfizer, Inc. Pharmaceutical combinations for the treatment of neurodegenerative diseases
DE10217006A1 (de) * 2002-04-16 2003-11-06 Merck Patent Gmbh Substituierte Indole
DE10259244A1 (de) * 2002-12-17 2004-07-01 Merck Patent Gmbh N-(Indolethyl-)cycloamin-Verbindungen
DE10305739A1 (de) 2003-02-11 2004-08-19 Merck Patent Gmbh Benzofuranderivate
DE10315285A1 (de) * 2003-04-04 2004-10-14 Merck Patent Gmbh Chromenonindole
GT200600414A (es) * 2005-09-12 2007-09-20 Sal de glucuranato de compuesto de piperazine
US9066903B2 (en) 2006-02-28 2015-06-30 The United States Of America As Represented By The Department Of Veterans Affairs Pharmacological treatment of Parkinson's disease
US9447310B2 (en) 2008-04-17 2016-09-20 Thomas P. Daly Biological buffers with wide buffering ranges
US7939659B2 (en) * 2008-04-17 2011-05-10 Thomas Daly Biological buffers with wide buffering ranges
US8034951B2 (en) * 2008-04-17 2011-10-11 Thomas Daly Biological buffers with wide buffering ranges
US20170313920A1 (en) 2010-10-06 2017-11-02 Thomas P. Daly Biological Buffers with Wide Buffering Ranges
US7635791B2 (en) * 2008-04-17 2009-12-22 Tpat Ip Llc Biological buffers with wide buffering ranges
US8334402B2 (en) * 2008-04-17 2012-12-18 Thomas Daly Biological buffers with wide buffering ranges
US9090638B2 (en) 2008-04-17 2015-07-28 Thomas Daly Biological buffers with wide buffering ranges
US8519141B2 (en) 2008-04-17 2013-08-27 Thomas Daly Biological buffers with wide buffering ranges
US8822728B2 (en) 2008-04-17 2014-09-02 Thomas Daly Biological buffers with wide buffering ranges
EP2374459A1 (en) * 2008-05-30 2011-10-12 Psychogenics Inc. Treatment for neurological and mental disorders
EP2429579A1 (en) 2009-05-12 2012-03-21 Transgene SA Immortalized avian cell lines and use thereof
CN102206214B (zh) * 2011-04-07 2014-03-12 华中科技大学 苯并吡喃酮类衍生物及其应用
US9475754B2 (en) 2011-10-06 2016-10-25 Thomas P. Daly Biological buffers with wide buffering ranges
KR102151963B1 (ko) * 2012-05-23 2020-09-07 네르비아노 메디칼 사이언시스 에스.알.엘. Ｎ-[5-(3,5-디플루오로-벤질)-1ｈ-인다졸-3-일]-4-(4-메틸-피페라진-1-일)-2-(테트라하이드로-피란-4-일아미노)-벤즈아미드의 제조 방법
EP3027607B1 (en) 2013-07-29 2020-08-26 Sunshine Lake Pharma Co., Ltd. Substituted heteroaryl compounds and methods of use thereof
CN105418506B (zh) * 2014-09-19 2018-04-24 上海医药工业研究院 乙酰苄胺哌嗪类衍生物及其作为脑神经保护剂的应用
US10316025B2 (en) 2015-06-03 2019-06-11 Sunshine Lake Pharma Co., Ltd. Substituted piperazine compounds and methods of use and use thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB146691A (en) * 1919-05-29 1920-07-15 William Herbert Tripp Apparatus for indicating and recording side drift or leeway of aircraft
FR2189027B1 (hu) * 1972-06-21 1976-03-05 Leurquin Laboratoires Fr
DE4333254A1 (de) * 1993-09-30 1995-04-06 Merck Patent Gmbh Piperidine und Piperazine
AU713573B2 (en) * 1996-07-26 1999-12-02 Nissan Chemical Industries Ltd. Chroman derivatives
DE69819173T2 (de) * 1997-07-25 2004-04-15 H. Lundbeck A/S Indole und 2,3-dihydroindolderivate, ihre herstellung und verwendung

Also Published As

Publication number Publication date
HUP0002718A2 (hu) 2001-10-28
JP2001510193A (ja) 2001-07-31
CA2296687A1 (en) 1999-01-28
RU2194048C2 (ru) 2002-12-10
BR9810607A (pt) 2000-07-11
NO20000216L (no) 2000-01-17
NO20000216D0 (no) 2000-01-17
CN1264379A (zh) 2000-08-23
ES2281131T3 (es) 2007-09-16
KR20010021957A (ko) 2001-03-15
CN1093127C (zh) 2002-10-23
PL338075A1 (en) 2000-09-25
MY132794A (en) 2007-10-31
AU731332B2 (en) 2001-03-29
DE19730989A1 (de) 1999-01-21
EP0998474A1 (de) 2000-05-10
AR010932A1 (es) 2000-07-12
UA59407C2 (uk) 2003-09-15
US6251908B1 (en) 2001-06-26
HUP0002718A3 (en) 2001-11-28
ID24663A (id) 2000-07-27
TW425398B (en) 2001-03-11
AU8730298A (en) 1999-02-10
KR100528684B1 (ko) 2005-11-15
PL191078B1 (pl) 2006-03-31
WO1999003855A1 (de) 1999-01-28
ATE353326T1 (de) 2007-02-15
EP0998474B1 (de) 2007-02-07
DE59813899D1 (de) 2007-03-22
SK352000A3 (en) 2000-06-12

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