ZA985918B - Process for the production of indole derivatives. - Google Patents

Process for the production of indole derivatives.

Info

Publication number
ZA985918B
ZA985918B ZA9805918A ZA985918A ZA985918B ZA 985918 B ZA985918 B ZA 985918B ZA 9805918 A ZA9805918 A ZA 9805918A ZA 985918 A ZA985918 A ZA 985918A ZA 985918 B ZA985918 B ZA 985918B
Authority
ZA
South Africa
Prior art keywords
production
indole derivatives
indole
derivatives
Prior art date
Application number
ZA9805918A
Other languages
English (en)
Inventor
David Charles Waite
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of ZA985918B publication Critical patent/ZA985918B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/01Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms
    • C07C311/02Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C311/03Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atoms of the sulfonamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/01Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms
    • C07C311/02Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C311/03Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atoms of the sulfonamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C311/04Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atoms of the sulfonamide groups bound to hydrogen atoms or to acyclic carbon atoms to acyclic carbon atoms of hydrocarbon radicals substituted by singly-bound oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C07D209/16Tryptamines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA9805918A 1997-07-08 1998-07-06 Process for the production of indole derivatives. ZA985918B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9714383.8A GB9714383D0 (en) 1997-07-08 1997-07-08 Improved process

Publications (1)

Publication Number Publication Date
ZA985918B true ZA985918B (en) 2000-01-10

Family

ID=10815557

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9805918A ZA985918B (en) 1997-07-08 1998-07-06 Process for the production of indole derivatives.

Country Status (15)

Country Link
US (1) US6281357B1 (da)
EP (1) EP0975594B1 (da)
AR (1) AR013183A1 (da)
AT (1) ATE224367T1 (da)
AU (1) AU8339798A (da)
CA (1) CA2286720A1 (da)
DE (1) DE69808068T2 (da)
DK (1) DK0975594T3 (da)
ES (1) ES2182342T3 (da)
GB (1) GB9714383D0 (da)
IL (1) IL132442A0 (da)
PL (1) PL337000A1 (da)
PT (1) PT975594E (da)
WO (1) WO1999002493A1 (da)
ZA (1) ZA985918B (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9801690D0 (en) * 1998-01-27 1998-03-25 Pfizer Ltd Therapeutic agents
US6100291A (en) * 1998-03-16 2000-08-08 Allelix Biopharmaceuticals Inc. Pyrrolidine-indole compounds having 5-HT6 affinity
CA2508290C (en) 2002-12-20 2017-02-28 Ciba Specialty Chemicals Holding Inc. Synthesis of amines and intermediates for the synthesis thereof
US20100022581A1 (en) * 2008-07-02 2010-01-28 Memory Pharmaceuticals Corporation Pyrrolidine-substituted azaindole compounds having 5-ht6 receptor affinity
CN102775342A (zh) * 2011-05-12 2012-11-14 上海医药工业研究院 一种抗偏头痛药物阿莫曲坦的制备方法
NZ763766A (en) 2017-03-20 2023-07-28 Novo Nordisk Healthcare Ag Pyrrolopyrrole compositions as pyruvate kinase (pkr) activators
EP3852791B1 (en) 2018-09-19 2024-07-03 Novo Nordisk Health Care AG Activating pyruvate kinase r
BR112021005188A2 (pt) 2018-09-19 2021-06-08 Forma Therapeutics, Inc. tratamento de anemia falciforme com um composto de ativação de piruvato cinase r
CN110483341A (zh) * 2019-07-23 2019-11-22 上海药明康德新药开发有限公司 一种1-氰基-n-甲基甲磺酰胺的合成方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8419575D0 (en) * 1984-08-01 1984-09-05 Glaxo Group Ltd Chemical compounds
RO111767B1 (ro) * 1990-10-15 1997-01-30 Pfizer Derivati de indol, procedee si intermediari pentru prepararea acestora, compozitii farmaceutice si metoda pentru tratarea unor afectiuni
GB9103770D0 (en) * 1991-02-22 1991-04-10 Glaxo Group Ltd Chemical compounds
CA2084531A1 (en) * 1991-12-19 1993-06-20 David W. Smith Antimigraine 4-pyrimidinyl and pyridinyl derivatives of indol-3yl-alkyl piperazines

Also Published As

Publication number Publication date
EP0975594B1 (en) 2002-09-18
PL337000A1 (en) 2000-07-31
PT975594E (pt) 2002-12-31
IL132442A0 (en) 2001-03-19
DE69808068T2 (de) 2003-02-06
WO1999002493A1 (en) 1999-01-21
DK0975594T3 (da) 2002-10-14
CA2286720A1 (en) 1999-01-21
AR013183A1 (es) 2000-12-13
GB9714383D0 (en) 1997-09-10
ES2182342T3 (es) 2003-03-01
DE69808068D1 (de) 2002-10-24
EP0975594A1 (en) 2000-02-02
AU8339798A (en) 1999-02-08
US6281357B1 (en) 2001-08-28
ATE224367T1 (de) 2002-10-15

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