ZA981976B - Indolyl-pyrrolydenemethylpyrrole derivatives and process for their preparation - Google Patents

Indolyl-pyrrolydenemethylpyrrole derivatives and process for their preparation

Info

Publication number
ZA981976B
ZA981976B ZA981976A ZA981976A ZA981976B ZA 981976 B ZA981976 B ZA 981976B ZA 981976 A ZA981976 A ZA 981976A ZA 981976 A ZA981976 A ZA 981976A ZA 981976 B ZA981976 B ZA 981976B
Authority
ZA
South Africa
Prior art keywords
pyrrolydenemethylpyrrole
indolyl
derivatives
preparation
pyrrolydenemethylpyrrole derivatives
Prior art date
Application number
ZA981976A
Other languages
English (en)
Inventor
Roberto D Alessio
Marcellino Tibolla
Alberto Bargiotti
Anna Maria Isetta
Mario Ferrari
Francesco Colotta
Original Assignee
Pharmacia & Upjohn Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia & Upjohn Spa filed Critical Pharmacia & Upjohn Spa
Publication of ZA981976B publication Critical patent/ZA981976B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Transplantation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Pyrrole Compounds (AREA)
ZA981976A 1997-03-11 1998-03-09 Indolyl-pyrrolydenemethylpyrrole derivatives and process for their preparation ZA981976B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9705035.5A GB9705035D0 (en) 1997-03-11 1997-03-11 Indolyl-pyrrolydenemethylpyrrole derivatives and process for their preparation

Publications (1)

Publication Number Publication Date
ZA981976B true ZA981976B (en) 1998-09-09

Family

ID=10809054

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA981976A ZA981976B (en) 1997-03-11 1998-03-09 Indolyl-pyrrolydenemethylpyrrole derivatives and process for their preparation

Country Status (26)

Country Link
US (1) US6071947A (fr)
EP (1) EP0909271B1 (fr)
JP (1) JP2000510873A (fr)
KR (1) KR20000010913A (fr)
CN (1) CN1089763C (fr)
AR (1) AR011964A1 (fr)
AT (1) ATE206118T1 (fr)
AU (1) AU740583B2 (fr)
BR (1) BR9805938A (fr)
CA (1) CA2253588A1 (fr)
DE (1) DE69801795T2 (fr)
DK (1) DK0909271T3 (fr)
EA (1) EA001055B1 (fr)
ES (1) ES2165150T3 (fr)
GB (1) GB9705035D0 (fr)
HU (1) HUP0003614A3 (fr)
IL (1) IL126839A (fr)
MY (1) MY117159A (fr)
NO (1) NO316754B1 (fr)
NZ (1) NZ333015A (fr)
PL (1) PL329808A1 (fr)
PT (1) PT909271E (fr)
TW (1) TW568911B (fr)
UA (1) UA56169C2 (fr)
WO (1) WO1998040380A1 (fr)
ZA (1) ZA981976B (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU775373B2 (en) 1999-10-01 2004-07-29 Immunogen, Inc. Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents
US20040014987A1 (en) 2000-01-26 2004-01-22 Gemin X Biotechnologies Inc. Pyrrole-Type compounds, compositions, and methods for treating cancer or viral diseases
US6407244B1 (en) 2000-01-26 2002-06-18 Gemin X Biotechnologies Inc. Pyrrole-type compounds, compositions, and methods for treating cancer or viral diseases
DE10038699A1 (de) * 2000-07-31 2002-02-14 Michael Sittinger Mittel zur Verringrung der Abstoßungsreaktionen bei Transplantaten
US7144912B2 (en) 2001-07-18 2006-12-05 Gemin X Biotechnologies Inc. Pyrrole-type compounds, compositions, and methods for treating cancer, treating viral diseases and causing immunosuppression
US7192939B2 (en) * 2002-01-30 2007-03-20 Montana State University Pestalotiopsis microsporia isolates and compounds derived therefrom
US7968569B2 (en) * 2002-05-17 2011-06-28 Celgene Corporation Methods for treatment of multiple myeloma using 3-(4-amino-1-oxo-1,3-dihydro-isoindol-2-yl)-piperidine-2,6-dione
SI1644363T1 (sl) * 2003-05-30 2012-07-31 Gemin X Pharmaceuticals Canada Inc Triheterociklične spojine sestavki in postopki za zdravljenje raka
US20110104186A1 (en) 2004-06-24 2011-05-05 Nicholas Valiante Small molecule immunopotentiators and assays for their detection
JP5224818B2 (ja) * 2004-12-28 2013-07-03 ジェミン エックス ファーマシューティカルズ カナダ インコーポレイテッド ジピロール化合物およびそれを含む医薬組成物
WO2006089397A1 (fr) * 2005-02-22 2006-08-31 Gemin X Biotechnologies Inc. Procédés pour traiter l’arthrite à l’aide de composés trihétérocycliques
DE102005025225A1 (de) 2005-06-01 2006-12-07 Sanofi-Aventis Deutschland Gmbh Verfahren zur Herstellung von 2-(2-Amino-pyrimidin-4-yl)-1H-indol-5-carbonsäure-derivaten
US20080051400A1 (en) * 2006-07-06 2008-02-28 Gemin X Biotechnologies Inc. Methods for treating or preventing anemia or thrombocytopenia using a triheterocyclic compound
CN113845524B (zh) * 2021-10-29 2023-11-07 四川农业大学 一种螺吡咯吲哚酮类化合物及其制备方法和应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61280429A (ja) * 1985-06-06 1986-12-11 Chugai Pharmaceut Co Ltd 免疫抑制剤
CN1121348A (zh) * 1993-04-22 1996-04-24 辉瑞研究及发展公司 吲哚衍生物作为5-ht1类激动剂用于治疗周期性偏头痛
GB9326284D0 (en) * 1993-12-23 1994-02-23 Erba Carlo Spa Pyrrolydenemethyl-derivatives and process for their preparation
GB9603212D0 (en) * 1996-02-15 1996-04-17 Pharmacia Spa Process for the preparation of 2,2'-bipyrrolyl-pyrromethane derivatives

Also Published As

Publication number Publication date
AU740583B2 (en) 2001-11-08
MY117159A (en) 2004-05-31
EP0909271A1 (fr) 1999-04-21
EP0909271B1 (fr) 2001-09-26
NO985248D0 (no) 1998-11-10
IL126839A (en) 2002-12-01
HUP0003614A2 (hu) 2001-10-28
TW568911B (en) 2004-01-01
KR20000010913A (ko) 2000-02-25
HUP0003614A3 (en) 2003-04-28
PT909271E (pt) 2002-03-28
NO316754B1 (no) 2004-04-26
DE69801795T2 (de) 2002-05-23
IL126839A0 (en) 1999-09-22
NO985248L (no) 1999-01-11
NZ333015A (en) 2000-04-28
CA2253588A1 (fr) 1998-09-17
CN1222911A (zh) 1999-07-14
EA199801004A1 (ru) 1999-06-24
DE69801795D1 (de) 2001-10-31
CN1089763C (zh) 2002-08-28
BR9805938A (pt) 1999-08-31
PL329808A1 (en) 1999-04-12
AU6828398A (en) 1998-09-29
GB9705035D0 (en) 1997-04-30
DK0909271T3 (da) 2002-01-28
ATE206118T1 (de) 2001-10-15
ES2165150T3 (es) 2002-03-01
WO1998040380A1 (fr) 1998-09-17
AR011964A1 (es) 2000-09-13
UA56169C2 (uk) 2003-05-15
EA001055B1 (ru) 2000-08-28
JP2000510873A (ja) 2000-08-22
US6071947A (en) 2000-06-06

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