IL126839A - History of indolyl-pyrrolidinemethylpyrol, process for their preparation and pharmaceutical preparations containing them - Google Patents

History of indolyl-pyrrolidinemethylpyrol, process for their preparation and pharmaceutical preparations containing them

Info

Publication number
IL126839A
IL126839A IL12683998A IL12683998A IL126839A IL 126839 A IL126839 A IL 126839A IL 12683998 A IL12683998 A IL 12683998A IL 12683998 A IL12683998 A IL 12683998A IL 126839 A IL126839 A IL 126839A
Authority
IL
Israel
Prior art keywords
methyl
pyrrol
ylidene
pyrrole
indol
Prior art date
Application number
IL12683998A
Other languages
English (en)
Hebrew (he)
Other versions
IL126839A0 (en
Original Assignee
Pharmacia & Upjohn Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia & Upjohn Spa filed Critical Pharmacia & Upjohn Spa
Publication of IL126839A0 publication Critical patent/IL126839A0/xx
Publication of IL126839A publication Critical patent/IL126839A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Transplantation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Pyrrole Compounds (AREA)
IL12683998A 1997-03-11 1998-02-27 History of indolyl-pyrrolidinemethylpyrol, process for their preparation and pharmaceutical preparations containing them IL126839A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9705035.5A GB9705035D0 (en) 1997-03-11 1997-03-11 Indolyl-pyrrolydenemethylpyrrole derivatives and process for their preparation
PCT/EP1998/001285 WO1998040380A1 (fr) 1997-03-11 1998-02-27 Derives d'indolyl-pyrrolydenemethylpyrrole et procede de preparation

Publications (2)

Publication Number Publication Date
IL126839A0 IL126839A0 (en) 1999-09-22
IL126839A true IL126839A (en) 2002-12-01

Family

ID=10809054

Family Applications (1)

Application Number Title Priority Date Filing Date
IL12683998A IL126839A (en) 1997-03-11 1998-02-27 History of indolyl-pyrrolidinemethylpyrol, process for their preparation and pharmaceutical preparations containing them

Country Status (26)

Country Link
US (1) US6071947A (fr)
EP (1) EP0909271B1 (fr)
JP (1) JP2000510873A (fr)
KR (1) KR20000010913A (fr)
CN (1) CN1089763C (fr)
AR (1) AR011964A1 (fr)
AT (1) ATE206118T1 (fr)
AU (1) AU740583B2 (fr)
BR (1) BR9805938A (fr)
CA (1) CA2253588A1 (fr)
DE (1) DE69801795T2 (fr)
DK (1) DK0909271T3 (fr)
EA (1) EA001055B1 (fr)
ES (1) ES2165150T3 (fr)
GB (1) GB9705035D0 (fr)
HU (1) HUP0003614A3 (fr)
IL (1) IL126839A (fr)
MY (1) MY117159A (fr)
NO (1) NO316754B1 (fr)
NZ (1) NZ333015A (fr)
PL (1) PL329808A1 (fr)
PT (1) PT909271E (fr)
TW (1) TW568911B (fr)
UA (1) UA56169C2 (fr)
WO (1) WO1998040380A1 (fr)
ZA (1) ZA981976B (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU775373B2 (en) 1999-10-01 2004-07-29 Immunogen, Inc. Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents
US20040014987A1 (en) 2000-01-26 2004-01-22 Gemin X Biotechnologies Inc. Pyrrole-Type compounds, compositions, and methods for treating cancer or viral diseases
US6407244B1 (en) 2000-01-26 2002-06-18 Gemin X Biotechnologies Inc. Pyrrole-type compounds, compositions, and methods for treating cancer or viral diseases
DE10038699A1 (de) * 2000-07-31 2002-02-14 Michael Sittinger Mittel zur Verringrung der Abstoßungsreaktionen bei Transplantaten
US7144912B2 (en) 2001-07-18 2006-12-05 Gemin X Biotechnologies Inc. Pyrrole-type compounds, compositions, and methods for treating cancer, treating viral diseases and causing immunosuppression
US7192939B2 (en) * 2002-01-30 2007-03-20 Montana State University Pestalotiopsis microsporia isolates and compounds derived therefrom
US7968569B2 (en) * 2002-05-17 2011-06-28 Celgene Corporation Methods for treatment of multiple myeloma using 3-(4-amino-1-oxo-1,3-dihydro-isoindol-2-yl)-piperidine-2,6-dione
SI1644363T1 (sl) * 2003-05-30 2012-07-31 Gemin X Pharmaceuticals Canada Inc Triheterociklične spojine sestavki in postopki za zdravljenje raka
US20110104186A1 (en) 2004-06-24 2011-05-05 Nicholas Valiante Small molecule immunopotentiators and assays for their detection
JP5224818B2 (ja) * 2004-12-28 2013-07-03 ジェミン エックス ファーマシューティカルズ カナダ インコーポレイテッド ジピロール化合物およびそれを含む医薬組成物
WO2006089397A1 (fr) * 2005-02-22 2006-08-31 Gemin X Biotechnologies Inc. Procédés pour traiter l’arthrite à l’aide de composés trihétérocycliques
DE102005025225A1 (de) 2005-06-01 2006-12-07 Sanofi-Aventis Deutschland Gmbh Verfahren zur Herstellung von 2-(2-Amino-pyrimidin-4-yl)-1H-indol-5-carbonsäure-derivaten
US20080051400A1 (en) * 2006-07-06 2008-02-28 Gemin X Biotechnologies Inc. Methods for treating or preventing anemia or thrombocytopenia using a triheterocyclic compound
CN113845524B (zh) * 2021-10-29 2023-11-07 四川农业大学 一种螺吡咯吲哚酮类化合物及其制备方法和应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61280429A (ja) * 1985-06-06 1986-12-11 Chugai Pharmaceut Co Ltd 免疫抑制剤
CN1121348A (zh) * 1993-04-22 1996-04-24 辉瑞研究及发展公司 吲哚衍生物作为5-ht1类激动剂用于治疗周期性偏头痛
GB9326284D0 (en) * 1993-12-23 1994-02-23 Erba Carlo Spa Pyrrolydenemethyl-derivatives and process for their preparation
GB9603212D0 (en) * 1996-02-15 1996-04-17 Pharmacia Spa Process for the preparation of 2,2'-bipyrrolyl-pyrromethane derivatives

Also Published As

Publication number Publication date
AU740583B2 (en) 2001-11-08
MY117159A (en) 2004-05-31
EP0909271A1 (fr) 1999-04-21
EP0909271B1 (fr) 2001-09-26
NO985248D0 (no) 1998-11-10
HUP0003614A2 (hu) 2001-10-28
TW568911B (en) 2004-01-01
KR20000010913A (ko) 2000-02-25
HUP0003614A3 (en) 2003-04-28
PT909271E (pt) 2002-03-28
NO316754B1 (no) 2004-04-26
DE69801795T2 (de) 2002-05-23
IL126839A0 (en) 1999-09-22
NO985248L (no) 1999-01-11
NZ333015A (en) 2000-04-28
CA2253588A1 (fr) 1998-09-17
CN1222911A (zh) 1999-07-14
EA199801004A1 (ru) 1999-06-24
DE69801795D1 (de) 2001-10-31
CN1089763C (zh) 2002-08-28
BR9805938A (pt) 1999-08-31
PL329808A1 (en) 1999-04-12
AU6828398A (en) 1998-09-29
GB9705035D0 (en) 1997-04-30
DK0909271T3 (da) 2002-01-28
ATE206118T1 (de) 2001-10-15
ZA981976B (en) 1998-09-09
ES2165150T3 (es) 2002-03-01
WO1998040380A1 (fr) 1998-09-17
AR011964A1 (es) 2000-09-13
UA56169C2 (uk) 2003-05-15
EA001055B1 (ru) 2000-08-28
JP2000510873A (ja) 2000-08-22
US6071947A (en) 2000-06-06

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Legal Events

Date Code Title Description
FF Patent granted
FF Patent granted
KB Patent renewed
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees
MM9K Patent not in force due to non-payment of renewal fees