ZA9810668B - Use of substitued aminomethyl-chromans for the prevention of neuronal degeneration and for the promotion of neuronal regeneration - Google Patents

Use of substitued aminomethyl-chromans for the prevention of neuronal degeneration and for the promotion of neuronal regeneration

Info

Publication number
ZA9810668B
ZA9810668B ZA9810668A ZA9810668A ZA9810668B ZA 9810668 B ZA9810668 B ZA 9810668B ZA 9810668 A ZA9810668 A ZA 9810668A ZA 9810668 A ZA9810668 A ZA 9810668A ZA 9810668 B ZA9810668 B ZA 9810668B
Authority
ZA
South Africa
Prior art keywords
neuronal
chromans
substitued
aminomethyl
promotion
Prior art date
Application number
ZA9810668A
Other languages
English (en)
Inventor
Thomas Fahrig
Irene Gerlach
Ervin Horvath
Reinhard Jork
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of ZA9810668B publication Critical patent/ZA9810668B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychology (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pyrane Compounds (AREA)
ZA9810668A 1997-11-24 1998-11-23 Use of substitued aminomethyl-chromans for the prevention of neuronal degeneration and for the promotion of neuronal regeneration ZA9810668B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19751949A DE19751949A1 (de) 1997-11-24 1997-11-24 Verwendung von substituierten Aminomethyl-Chromanen zur Verhinderung der neuronalen Degeneration und zur Förderung der neuronalen Regeneration

Publications (1)

Publication Number Publication Date
ZA9810668B true ZA9810668B (en) 1999-05-26

Family

ID=7849618

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9810668A ZA9810668B (en) 1997-11-24 1998-11-23 Use of substitued aminomethyl-chromans for the prevention of neuronal degeneration and for the promotion of neuronal regeneration

Country Status (30)

Country Link
US (2) US6235774B1 (enExample)
EP (1) EP1051170B1 (enExample)
JP (1) JP2001523716A (enExample)
KR (1) KR20010032357A (enExample)
CN (1) CN1134256C (enExample)
AR (1) AR016973A1 (enExample)
AT (1) ATE206615T1 (enExample)
AU (1) AU745759B2 (enExample)
BG (1) BG64167B1 (enExample)
CA (1) CA2311126A1 (enExample)
DE (2) DE19751949A1 (enExample)
DK (1) DK1051170T3 (enExample)
ES (1) ES2164465T3 (enExample)
HN (1) HN1998000169A (enExample)
HU (1) HUP0004369A3 (enExample)
IL (1) IL135904A (enExample)
IS (1) IS5496A (enExample)
MY (1) MY118414A (enExample)
NO (1) NO20002638L (enExample)
NZ (1) NZ504656A (enExample)
PE (1) PE134999A1 (enExample)
PL (1) PL340674A1 (enExample)
PT (1) PT1051170E (enExample)
RU (1) RU2217140C2 (enExample)
SI (1) SI1051170T1 (enExample)
SV (1) SV1998000138A (enExample)
TR (1) TR200001471T2 (enExample)
TW (1) TW524690B (enExample)
WO (1) WO1999026621A1 (enExample)
ZA (1) ZA9810668B (enExample)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19751949A1 (de) * 1997-11-24 1999-05-27 Bayer Ag Verwendung von substituierten Aminomethyl-Chromanen zur Verhinderung der neuronalen Degeneration und zur Förderung der neuronalen Regeneration
UA73981C2 (en) * 2000-03-10 2005-10-17 Merck Patent Gmbh (r)-(-)-2-[5-(4-fluorophenyl)-3-pyridylmethylaminomethyl]-chromane for treatment of extrapyramidal movement disorders (variants), pharmaceutical composition and kit
MXPA02009071A (es) * 2000-03-17 2003-05-23 Alcon Inc Compuestos con actividad agonista de 5-ht 1a para tratar glaucoma..
US20030207890A1 (en) 2001-02-23 2003-11-06 Collier Robert J Compounds with 5-ht1a activity useful for treating disorders of the outer retina
DE10058119A1 (de) * 2000-11-22 2002-05-23 Bayer Ag Pepinotan-Kit
SE0004455D0 (sv) * 2000-12-01 2000-12-01 Milos Pekny Method for neuron regeneration in the central nervous system
DE10101917A1 (de) * 2001-01-16 2002-07-18 Bayer Ag Verwendung von Chromanen
AU2002355170B2 (en) * 2001-07-26 2007-06-07 Merck Patent Gmbh Novel use of 2-[5-(4-fluorophenyl)-3-pyridylmethylaminomethyl]-chromane and its physiologically acceptable salts
ATE341322T1 (de) * 2001-09-12 2006-10-15 Merck Patent Gmbh Verwendung von aminomethyl chromanen zur behandlung der nebenwirkungen von neuroleptika
DE10155075A1 (de) * 2001-11-09 2003-05-22 Merck Patent Gmbh Cyclische Sulfonamide
ITTO20030140U1 (it) * 2003-09-16 2005-03-17 Interfila Srl Matita cosmetica
CA2580584C (en) 2003-09-19 2015-07-28 Galileo Pharmaceuticals, Inc. Use of alpha-tocotrienol for treatment of mitochondrial diseases
DE102004017627A1 (de) * 2004-04-10 2005-10-27 Bayer Healthcare Ag Verwendung von vollen 5-HT1A-Agonisten zur Hemmung der opiat/opioid-induzierten Atemdepression
ES2996835T3 (en) 2016-07-29 2025-02-13 Sumitomo Pharma America Inc Compounds and compositions and uses thereof
MA45795A (fr) 2016-07-29 2019-06-05 Sunovion Pharmaceuticals Inc Composés et compositions, et utilisations associées
RU2651756C1 (ru) * 2017-05-10 2018-04-23 Федеральное государственное бюджетное образовательное учреждение Высшего Образования Кубанский Государственный Медицинский Университет Министерства Здравоохранения Российской Федерации, КубГМУ Препарат для предотвращения образования глиальных рубцов
AU2018312559B2 (en) * 2017-08-02 2022-06-02 Pgi Drug Discovery Llc Isochroman compounds and uses thereof
WO2020186165A1 (en) 2019-03-14 2020-09-17 Sunovion Pharmaceuticals Inc. Salts of a isochromanyl compound and crystalline forms, processes for preparing, therapeutic uses, and pharmaceutical compositions thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5300523A (en) 1988-07-28 1994-04-05 Bayer Aktiengesellschaft Substituted aminomethyltetralins and their heterocyclic analogues
DE3901814A1 (de) * 1988-07-28 1990-02-01 Bayer Ag Substituierte aminomethylzetraline sowie ihre heterocyclischen analoga
FR2662355B1 (fr) * 1990-05-22 1994-11-10 Sanofi Sa Utilisation de la 1-[2-(2-naphtyl)ethyl]-4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridine pour la preparation de medicaments destines au traitement de troubles cerebraux et neuronaux.
GB9012316D0 (en) * 1990-06-01 1990-07-18 Wellcome Found Pharmacologically active cns compounds
DE4135474A1 (de) 1991-10-28 1993-04-29 Bayer Ag 2-aminomethyl-chromane
DE19522088A1 (de) 1995-06-19 1997-01-02 Bayer Ag Benzisothiazolyl-substituierte Aminomethylchromane
DE19751949A1 (de) * 1997-11-24 1999-05-27 Bayer Ag Verwendung von substituierten Aminomethyl-Chromanen zur Verhinderung der neuronalen Degeneration und zur Förderung der neuronalen Regeneration

Also Published As

Publication number Publication date
DE59801724D1 (de) 2001-11-15
NO20002638D0 (no) 2000-05-23
TW524690B (en) 2003-03-21
CN1279604A (zh) 2001-01-10
EP1051170A1 (de) 2000-11-15
NO20002638L (no) 2000-05-23
IS5496A (is) 2000-05-15
AU745759B2 (en) 2002-03-28
US6235774B1 (en) 2001-05-22
ES2164465T3 (es) 2002-02-16
CN1134256C (zh) 2004-01-14
ATE206615T1 (de) 2001-10-15
AR016973A1 (es) 2001-08-01
JP2001523716A (ja) 2001-11-27
BG104466A (en) 2001-02-28
HUP0004369A3 (en) 2002-04-29
MY118414A (en) 2004-10-30
IL135904A0 (en) 2001-05-20
HN1998000169A (es) 1999-11-03
HUP0004369A2 (hu) 2001-04-28
SV1998000138A (es) 1999-05-25
PT1051170E (pt) 2002-02-28
US6331561B2 (en) 2001-12-18
NZ504656A (en) 2002-02-01
KR20010032357A (ko) 2001-04-16
TR200001471T2 (tr) 2000-10-23
PE134999A1 (es) 2000-03-05
DE19751949A1 (de) 1999-05-27
EP1051170B1 (de) 2001-10-10
US20010018530A1 (en) 2001-08-30
DK1051170T3 (da) 2001-12-27
SI1051170T1 (en) 2001-12-31
PL340674A1 (en) 2001-02-12
IL135904A (en) 2003-07-06
BG64167B1 (bg) 2004-03-31
CA2311126A1 (en) 1999-06-03
WO1999026621A1 (de) 1999-06-03
AU1668599A (en) 1999-06-15
RU2217140C2 (ru) 2003-11-27

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