ZA9810668B - Use of substitued aminomethyl-chromans for the prevention of neuronal degeneration and for the promotion of neuronal regeneration - Google Patents

Use of substitued aminomethyl-chromans for the prevention of neuronal degeneration and for the promotion of neuronal regeneration

Info

Publication number
ZA9810668B
ZA9810668B ZA9810668A ZA9810668A ZA9810668B ZA 9810668 B ZA9810668 B ZA 9810668B ZA 9810668 A ZA9810668 A ZA 9810668A ZA 9810668 A ZA9810668 A ZA 9810668A ZA 9810668 B ZA9810668 B ZA 9810668B
Authority
ZA
South Africa
Prior art keywords
neuronal
chromans
substitued
aminomethyl
promotion
Prior art date
Application number
ZA9810668A
Other languages
English (en)
Inventor
Thomas Fahrig
Irene Gerlach
Ervin Horvath
Reinhard Jork
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of ZA9810668B publication Critical patent/ZA9810668B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ZA9810668A 1997-11-24 1998-11-23 Use of substitued aminomethyl-chromans for the prevention of neuronal degeneration and for the promotion of neuronal regeneration ZA9810668B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19751949A DE19751949A1 (de) 1997-11-24 1997-11-24 Verwendung von substituierten Aminomethyl-Chromanen zur Verhinderung der neuronalen Degeneration und zur Förderung der neuronalen Regeneration

Publications (1)

Publication Number Publication Date
ZA9810668B true ZA9810668B (en) 1999-05-26

Family

ID=7849618

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9810668A ZA9810668B (en) 1997-11-24 1998-11-23 Use of substitued aminomethyl-chromans for the prevention of neuronal degeneration and for the promotion of neuronal regeneration

Country Status (30)

Country Link
US (2) US6235774B1 (enExample)
EP (1) EP1051170B1 (enExample)
JP (1) JP2001523716A (enExample)
KR (1) KR20010032357A (enExample)
CN (1) CN1134256C (enExample)
AR (1) AR016973A1 (enExample)
AT (1) ATE206615T1 (enExample)
AU (1) AU745759B2 (enExample)
BG (1) BG64167B1 (enExample)
CA (1) CA2311126A1 (enExample)
DE (2) DE19751949A1 (enExample)
DK (1) DK1051170T3 (enExample)
ES (1) ES2164465T3 (enExample)
HN (1) HN1998000169A (enExample)
HU (1) HUP0004369A3 (enExample)
IL (1) IL135904A (enExample)
IS (1) IS5496A (enExample)
MY (1) MY118414A (enExample)
NO (1) NO20002638D0 (enExample)
NZ (1) NZ504656A (enExample)
PE (1) PE134999A1 (enExample)
PL (1) PL340674A1 (enExample)
PT (1) PT1051170E (enExample)
RU (1) RU2217140C2 (enExample)
SI (1) SI1051170T1 (enExample)
SV (1) SV1998000138A (enExample)
TR (1) TR200001471T2 (enExample)
TW (1) TW524690B (enExample)
WO (1) WO1999026621A1 (enExample)
ZA (1) ZA9810668B (enExample)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19751949A1 (de) * 1997-11-24 1999-05-27 Bayer Ag Verwendung von substituierten Aminomethyl-Chromanen zur Verhinderung der neuronalen Degeneration und zur Förderung der neuronalen Regeneration
UA73981C2 (en) * 2000-03-10 2005-10-17 Merck Patent Gmbh (r)-(-)-2-[5-(4-fluorophenyl)-3-pyridylmethylaminomethyl]-chromane for treatment of extrapyramidal movement disorders (variants), pharmaceutical composition and kit
MXPA02009071A (es) * 2000-03-17 2003-05-23 Alcon Inc Compuestos con actividad agonista de 5-ht 1a para tratar glaucoma..
US20030207890A1 (en) 2001-02-23 2003-11-06 Collier Robert J Compounds with 5-ht1a activity useful for treating disorders of the outer retina
DE10058119A1 (de) * 2000-11-22 2002-05-23 Bayer Ag Pepinotan-Kit
SE0004455D0 (sv) * 2000-12-01 2000-12-01 Milos Pekny Method for neuron regeneration in the central nervous system
DE10101917A1 (de) * 2001-01-16 2002-07-18 Bayer Ag Verwendung von Chromanen
BR0211358A (pt) * 2001-07-26 2004-09-21 Merck Patent Gmbh Uso do composto de 2-[5-(4-fluorofenil)-3-piridilmetilaminometil]-croman o e seus sais fisiologicamente aceitáveis
KR100886185B1 (ko) * 2001-09-12 2009-02-27 메르크 파텐트 게엠베하 운동 장애의 치료 및 추체외로 운동 장애의 치료를 위해 투여된 약물에 의해 유도된 부작용의 치료를 위한 치환된 아미노메틸 크로만의 신규한 용도
DE10155075A1 (de) * 2001-11-09 2003-05-22 Merck Patent Gmbh Cyclische Sulfonamide
ITTO20030140U1 (it) * 2003-09-16 2005-03-17 Interfila Srl Matita cosmetica
CA2580584C (en) * 2003-09-19 2015-07-28 Galileo Pharmaceuticals, Inc. Use of alpha-tocotrienol for treatment of mitochondrial diseases
DE102004017627A1 (de) * 2004-04-10 2005-10-27 Bayer Healthcare Ag Verwendung von vollen 5-HT1A-Agonisten zur Hemmung der opiat/opioid-induzierten Atemdepression
EA201990400A1 (ru) 2016-07-29 2019-07-31 Суновион Фармасьютикалз, Инк. Соединения и композиции и их применение
MX2019000982A (es) 2016-07-29 2019-07-04 Sunovion Pharmaceuticals Inc Compuestos y composiciones y usos de los mismos.
RU2651756C1 (ru) * 2017-05-10 2018-04-23 Федеральное государственное бюджетное образовательное учреждение Высшего Образования Кубанский Государственный Медицинский Университет Министерства Здравоохранения Российской Федерации, КубГМУ Препарат для предотвращения образования глиальных рубцов
JP7191085B2 (ja) * 2017-08-02 2022-12-16 サノビオン ファーマシューティカルズ インク イソクロマン化合物およびその使用
CN113784755B (zh) 2019-03-14 2024-05-10 赛诺维信制药公司 异色满基化合物的盐及其结晶形式、制备方法、治疗用途和药物组合物

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3901814A1 (de) * 1988-07-28 1990-02-01 Bayer Ag Substituierte aminomethylzetraline sowie ihre heterocyclischen analoga
US5300523A (en) 1988-07-28 1994-04-05 Bayer Aktiengesellschaft Substituted aminomethyltetralins and their heterocyclic analogues
FR2662355B1 (fr) * 1990-05-22 1994-11-10 Sanofi Sa Utilisation de la 1-[2-(2-naphtyl)ethyl]-4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridine pour la preparation de medicaments destines au traitement de troubles cerebraux et neuronaux.
GB9012316D0 (en) * 1990-06-01 1990-07-18 Wellcome Found Pharmacologically active cns compounds
DE4135474A1 (de) * 1991-10-28 1993-04-29 Bayer Ag 2-aminomethyl-chromane
DE19522088A1 (de) 1995-06-19 1997-01-02 Bayer Ag Benzisothiazolyl-substituierte Aminomethylchromane
DE19751949A1 (de) * 1997-11-24 1999-05-27 Bayer Ag Verwendung von substituierten Aminomethyl-Chromanen zur Verhinderung der neuronalen Degeneration und zur Förderung der neuronalen Regeneration

Also Published As

Publication number Publication date
TW524690B (en) 2003-03-21
ES2164465T3 (es) 2002-02-16
KR20010032357A (ko) 2001-04-16
EP1051170A1 (de) 2000-11-15
HUP0004369A2 (hu) 2001-04-28
PT1051170E (pt) 2002-02-28
WO1999026621A1 (de) 1999-06-03
NO20002638L (no) 2000-05-23
DK1051170T3 (da) 2001-12-27
PE134999A1 (es) 2000-03-05
IS5496A (is) 2000-05-15
AU745759B2 (en) 2002-03-28
MY118414A (en) 2004-10-30
AU1668599A (en) 1999-06-15
CN1134256C (zh) 2004-01-14
DE19751949A1 (de) 1999-05-27
AR016973A1 (es) 2001-08-01
US6331561B2 (en) 2001-12-18
CA2311126A1 (en) 1999-06-03
BG64167B1 (bg) 2004-03-31
BG104466A (en) 2001-02-28
HN1998000169A (es) 1999-11-03
ATE206615T1 (de) 2001-10-15
EP1051170B1 (de) 2001-10-10
HUP0004369A3 (en) 2002-04-29
IL135904A0 (en) 2001-05-20
PL340674A1 (en) 2001-02-12
NZ504656A (en) 2002-02-01
TR200001471T2 (tr) 2000-10-23
IL135904A (en) 2003-07-06
CN1279604A (zh) 2001-01-10
JP2001523716A (ja) 2001-11-27
SI1051170T1 (en) 2001-12-31
RU2217140C2 (ru) 2003-11-27
NO20002638D0 (no) 2000-05-23
DE59801724D1 (de) 2001-11-15
US20010018530A1 (en) 2001-08-30
US6235774B1 (en) 2001-05-22
SV1998000138A (es) 1999-05-25

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