ZA97905B - Continuous processes for the hydrolysis of cyanopyridines under substantially adiabatic conditions. - Google Patents

Continuous processes for the hydrolysis of cyanopyridines under substantially adiabatic conditions.

Info

Publication number
ZA97905B
ZA97905B ZA9700905A ZA97905A ZA97905B ZA 97905 B ZA97905 B ZA 97905B ZA 9700905 A ZA9700905 A ZA 9700905A ZA 97905 A ZA97905 A ZA 97905A ZA 97905 B ZA97905 B ZA 97905B
Authority
ZA
South Africa
Prior art keywords
cyanopyridines
hydrolysis
under substantially
continuous processes
adiabatic conditions
Prior art date
Application number
ZA9700905A
Other languages
English (en)
Inventor
Wei Cao
Robert A Cattau
George Kreilis
Original Assignee
Reilly Ind Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Reilly Ind Inc filed Critical Reilly Ind Inc
Publication of ZA97905B publication Critical patent/ZA97905B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/84—Nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C07D213/803—Processes of preparation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyridine Compounds (AREA)
ZA9700905A 1996-02-09 1997-02-04 Continuous processes for the hydrolysis of cyanopyridines under substantially adiabatic conditions. ZA97905B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US1142496P 1996-02-09 1996-02-09

Publications (1)

Publication Number Publication Date
ZA97905B true ZA97905B (en) 1997-08-01

Family

ID=21750315

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9700905A ZA97905B (en) 1996-02-09 1997-02-04 Continuous processes for the hydrolysis of cyanopyridines under substantially adiabatic conditions.

Country Status (12)

Country Link
US (1) US5756750A (ja)
EP (1) EP1021408A4 (ja)
JP (1) JP2000504686A (ja)
KR (1) KR19990082368A (ja)
CN (1) CN1173949C (ja)
AU (1) AU2254697A (ja)
BR (1) BR9707375A (ja)
IN (1) IN182600B (ja)
RU (1) RU2175968C2 (ja)
TW (1) TW453996B (ja)
WO (1) WO1997029087A1 (ja)
ZA (1) ZA97905B (ja)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW539670B (en) 1998-07-21 2003-07-01 Reilly Ind Inc Processes for producing highly pure nicotinamide
US20050089987A1 (en) * 2003-10-27 2005-04-28 Lonza Ltd. Polyacryamide beads containing encapsulated cells
EP1982977A1 (de) * 2007-04-20 2008-10-22 Lonza Ag Verfahren zur Hydrolyse von heteroaromatischen Nitrilen in wässrigen Fluiden
CA2680356A1 (en) * 2007-04-20 2008-10-30 Lonza Ag Method for the hydrolysis of heteroaromatic nitriles in aqueous fluids
EP3162796B1 (en) * 2014-06-27 2021-06-09 Agro-Kanesho Co., Ltd. Method for producing 2-amino-6-methylnicotinic acid
CN104496894A (zh) * 2014-11-22 2015-04-08 安徽国星生物化学有限公司 一种高纯度烟酰胺及烟酸的制备方法
CN104496895B (zh) * 2014-12-18 2017-02-01 天津汉德威药业有限公司 一种水解制备异烟酸的方法
GB2588165B (en) * 2019-10-10 2021-10-20 Nelson Mandela Univ A continuous flow synthesis method for the manufacture of isoniazid

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2471518A (en) * 1949-05-31 Nicotinic acid amide and processes
US2904552A (en) * 1958-07-21 1959-09-15 Distillers Co Yeast Ltd Production of nicotinamide and isonicotinamide
US3632635A (en) * 1966-09-01 1972-01-04 Halcon International Inc Aromatic dinitrile conversion process
US3776949A (en) * 1971-09-07 1973-12-04 Lummus Co Production of aromatic polycarboxylic acids
DE2517054C2 (de) * 1975-04-17 1985-04-25 Degussa Ag, 6000 Frankfurt Verfahren zur Herstellung von Nicotinsäureamid
DE2517053A1 (de) * 1975-04-17 1976-10-28 Degussa Verfahren zur gewinnung von nicotinsaeureamid
US4008241A (en) * 1975-09-02 1977-02-15 The Lummus Company Nicotinamide production
NL7706612A (en) * 1977-06-16 1978-12-19 Stamicarbon Nicotinamide prepn. from aq. 3-cyano-pyridine soln. - by hydrolysis with anion exchanger and extraction with organic solvent
US4327219A (en) * 1980-04-21 1982-04-27 The Lummus Company Nicotinamide production
US4503231A (en) * 1983-07-25 1985-03-05 The Lummus Company Hydrolysis of nitriles to amides with quaternary ammonium hydroxide
SU1288183A1 (ru) * 1985-03-11 1987-02-07 Институт химических наук АН КазССР Способ получени изоникотиновой кислоты
DE3614019A1 (de) * 1986-04-25 1987-11-05 Degussa Verfahren zur herstellung grobkristalliner nicotinsaeure hoher reinheit
SU1553531A1 (ru) 1988-02-10 1990-03-30 Институт химических наук АН КазССР Способ получени пиридин-4-карбоксамида
JPH057000A (ja) * 1991-06-28 1993-01-14 Nippon Sheet Glass Co Ltd ａ−Ｓｉを用いた薄膜トランジスタ
JP3409353B2 (ja) * 1992-04-30 2003-05-26 住友化学工業株式会社 アミド化合物の製造方法および使用される微生物

Also Published As

Publication number Publication date
CN1214679A (zh) 1999-04-21
WO1997029087A1 (en) 1997-08-14
BR9707375A (pt) 1999-07-20
TW453996B (en) 2001-09-11
EP1021408A1 (en) 2000-07-26
EP1021408A4 (en) 2000-07-26
AU2254697A (en) 1997-08-28
CN1173949C (zh) 2004-11-03
RU2175968C2 (ru) 2001-11-20
JP2000504686A (ja) 2000-04-18
IN182600B (ja) 1999-05-15
KR19990082368A (ko) 1999-11-25
US5756750A (en) 1998-05-26

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