NL7706612A - Nicotinamide prepn. from aq. 3-cyano-pyridine soln. - by hydrolysis with anion exchanger and extraction with organic solvent - Google Patents

Nicotinamide prepn. from aq. 3-cyano-pyridine soln. - by hydrolysis with anion exchanger and extraction with organic solvent

Info

Publication number
NL7706612A
NL7706612A NL7706612A NL7706612A NL7706612A NL 7706612 A NL7706612 A NL 7706612A NL 7706612 A NL7706612 A NL 7706612A NL 7706612 A NL7706612 A NL 7706612A NL 7706612 A NL7706612 A NL 7706612A
Authority
NL
Netherlands
Prior art keywords
soln
pref
prepn
nicotinamide
organic solvent
Prior art date
Application number
NL7706612A
Other languages
Dutch (nl)
Original Assignee
Stamicarbon
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Stamicarbon filed Critical Stamicarbon
Priority to NL7706612A priority Critical patent/NL7706612A/en
Publication of NL7706612A publication Critical patent/NL7706612A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides

Abstract

Prepn. of nicotinamide (I) is carried out by (a) passing an aq. soln. of 3-cyanopyridine (II) over a basic anion exchanger in the OH- form, and (b) extracting the reaction mixt. with an organic solvent to obtain an aq. soln. of (I). (The hourly space velocity is pref. 0.2-1.5g of (II) per mol of ion exchanger. The feed soln. pref. contains 5-50 wt % of (II). The reaction temp. is pref. 25-60 degrees C. The ion exchanger is pref. a strongly basic type, e.g. 'Dowex 1 x 4' or 'Imac S-5-50'. The extraction solvent can be e.g. pet, ether, toluene, benzene, CHCl3 or ether, esp. toluene). The process is less expensive to operate than that of PO 78808, and the prod. can be recovered by evaporating the aq. soln. (rather than cystn.). Once-through conversions of 47-83% can be obtained, with 91-97% selectivity for (I).
NL7706612A 1977-06-16 1977-06-16 Nicotinamide prepn. from aq. 3-cyano-pyridine soln. - by hydrolysis with anion exchanger and extraction with organic solvent NL7706612A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
NL7706612A NL7706612A (en) 1977-06-16 1977-06-16 Nicotinamide prepn. from aq. 3-cyano-pyridine soln. - by hydrolysis with anion exchanger and extraction with organic solvent

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL7706612A NL7706612A (en) 1977-06-16 1977-06-16 Nicotinamide prepn. from aq. 3-cyano-pyridine soln. - by hydrolysis with anion exchanger and extraction with organic solvent

Publications (1)

Publication Number Publication Date
NL7706612A true NL7706612A (en) 1978-12-19

Family

ID=19828729

Family Applications (1)

Application Number Title Priority Date Filing Date
NL7706612A NL7706612A (en) 1977-06-16 1977-06-16 Nicotinamide prepn. from aq. 3-cyano-pyridine soln. - by hydrolysis with anion exchanger and extraction with organic solvent

Country Status (1)

Country Link
NL (1) NL7706612A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5756750A (en) * 1996-02-09 1998-05-26 Reilly Industries, Inc. Continuous processes for the hydrolysis of cyanopyridines under substantially adiabatic conditions
US6218543B1 (en) 1998-07-21 2001-04-17 Martin Grendze Processes for producing highly pure nicotinamide

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5756750A (en) * 1996-02-09 1998-05-26 Reilly Industries, Inc. Continuous processes for the hydrolysis of cyanopyridines under substantially adiabatic conditions
US6218543B1 (en) 1998-07-21 2001-04-17 Martin Grendze Processes for producing highly pure nicotinamide

Similar Documents

Publication Publication Date Title
BE847081A (en) TWO-STAGE ATTACK PROCESS OF NATURAL PRODUCTS CONTAINING XYLANE FOR THE RECOVERY OF XYLOSE,
ES550516A0 (en) PROCEDURE TO RECOVER VALUABLE AMOUNTS OF ZINC
NL7706612A (en) Nicotinamide prepn. from aq. 3-cyano-pyridine soln. - by hydrolysis with anion exchanger and extraction with organic solvent
FR2327314A1 (en) TWO-STAGE ATTACK PROCESS OF HEMICELLULOSES OF NATURAL PRODUCTS CONTAINING XYLANE FOR THE RECOVERY OF XYLOSE
BE839961A (en) PROCESS FOR EXTRACTING COPPER FROM AQUEOUS SOLUTIONS WITH HYDROXY OXIMES
KR860009057A (en) Method of producing epoxy resin
JPS5423900A (en) Recovering regeneration method of radioactive retreating waste organic solvent
IL52552A (en) Solvent extraction process for preparing phospate salts with recovery of organic solvent from the aqueous raffinate
GB1317480A (en) Method for the recovery of molybdenum
EP0051681A4 (en) Process for preparing a dibenzylidenesorbitol or a dibenzylidenexylitol.
KR830001880A (en) Recovery method of cyclohexanone oxime
JPS51136634A (en) Process for recovery of reaction residue as a powder
ES223348A1 (en) Recovery of cyclohexanone oxime
JPS5650113A (en) Recovering method for lithium from bittern
ES318064A1 (en) Process for the recovery of methionine
ES477395A1 (en) Recovery of Cr2O3 from a Chromium Bearing Solution
Shono et al. FIRST SYNTHESIS OF AN EPIMER OF (±)-PENTENOMYCIN I
JPS53133283A (en) High polymers bonded to adenine nucleotide derivatives
Martin Soil organic phosphorus
FR2432009A1 (en) Meta-phenoxy-benzaldehyde preparation - by reacting bromo-benzene with dioxolan deriv. of meta-hydroxy-benzaldehyde using copper catalyst and alkaline cpd., then acid hydrolysis
JPS53119807A (en) Separation of butanediol
Salas FUNDAMENTAL RESEARCH ON ROTOR TILLAGE & ITS POWER UNITS (8)
JPS52107489A (en) Control system of mover
JPS53137983A (en) Recovery of epsilon-caprolactam
JPS5377976A (en) Accident recorder

Legal Events

Date Code Title Description
BV The patent application has lapsed