ZA973961B - Crystalline(-)3R,4R-trans-7-methoxy-2,2-dimethyl-3-phenyl-4-(4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)chromane, hydrogen fumarate. - Google Patents

Crystalline(-)3R,4R-trans-7-methoxy-2,2-dimethyl-3-phenyl-4-(4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)chromane, hydrogen fumarate.

Info

Publication number
ZA973961B
ZA973961B ZA9703961A ZA973961A ZA973961B ZA 973961 B ZA973961 B ZA 973961B ZA 9703961 A ZA9703961 A ZA 9703961A ZA 973961 A ZA973961 A ZA 973961A ZA 973961 B ZA973961 B ZA 973961B
Authority
ZA
South Africa
Prior art keywords
phenyl
chromane
ethoxy
trans
methoxy
Prior art date
Application number
ZA9703961A
Other languages
English (en)
Inventor
Svend Treppendahl
Klaus Snej Jensen
Scott E Mcgraw
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of ZA973961B publication Critical patent/ZA973961B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pyrrole Compounds (AREA)
ZA9703961A 1996-05-08 1997-05-08 Crystalline(-)3R,4R-trans-7-methoxy-2,2-dimethyl-3-phenyl-4-(4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)chromane, hydrogen fumarate. ZA973961B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK55296 1996-05-08

Publications (1)

Publication Number Publication Date
ZA973961B true ZA973961B (en) 1997-12-04

Family

ID=8094838

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9703961A ZA973961B (en) 1996-05-08 1997-05-08 Crystalline(-)3R,4R-trans-7-methoxy-2,2-dimethyl-3-phenyl-4-(4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)chromane, hydrogen fumarate.

Country Status (17)

Country Link
EP (1) EP0912543B1 (no)
JP (1) JP2951410B2 (no)
KR (1) KR20000010644A (no)
CN (1) CN1218462A (no)
AT (1) ATE262516T1 (no)
AU (1) AU710334B2 (no)
BR (1) BR9709060A (no)
CA (1) CA2253284A1 (no)
CZ (1) CZ359898A3 (no)
DE (1) DE69728271D1 (no)
HU (1) HUP9901738A3 (no)
IL (1) IL126345A (no)
NO (1) NO985205D0 (no)
PL (1) PL329624A1 (no)
RU (1) RU2182149C2 (no)
WO (1) WO1997042184A1 (no)
ZA (1) ZA973961B (no)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104166678B (zh) * 2014-07-09 2018-04-10 苏州市职业大学 一种面向汉语微博的多种潜在属性整体挖掘系统及方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5280040A (en) * 1993-03-11 1994-01-18 Zymogenetics, Inc. Methods for reducing bone loss using centchroman derivatives
US5407955A (en) * 1994-02-18 1995-04-18 Eli Lilly And Company Methods for lowering serum cholesterol and inhibiting smooth muscle cell proliferation, restenosis, endometriosis, and uterine fibroid disease

Also Published As

Publication number Publication date
BR9709060A (pt) 1999-08-03
CA2253284A1 (en) 1997-11-13
WO1997042184A1 (en) 1997-11-13
NO985205L (no) 1998-11-06
JP2951410B2 (ja) 1999-09-20
EP0912543A1 (en) 1999-05-06
DE69728271D1 (en) 2004-04-29
ATE262516T1 (de) 2004-04-15
HUP9901738A2 (en) 2000-07-28
IL126345A0 (en) 1999-05-09
AU710334B2 (en) 1999-09-16
NO985205D0 (no) 1998-11-06
EP0912543B1 (en) 2004-03-24
JPH11501953A (ja) 1999-02-16
IL126345A (en) 2001-07-24
KR20000010644A (ko) 2000-02-25
CN1218462A (zh) 1999-06-02
HUP9901738A3 (en) 2000-12-28
CZ359898A3 (cs) 1999-05-12
RU2182149C2 (ru) 2002-05-10
PL329624A1 (en) 1999-03-29
AU2763897A (en) 1997-11-26

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