ZA973894B - 6-0 substituted erythromycins and method for making same. - Google Patents

6-0 substituted erythromycins and method for making same.

Info

Publication number
ZA973894B
ZA973894B ZA9703894A ZA973894A ZA973894B ZA 973894 B ZA973894 B ZA 973894B ZA 9703894 A ZA9703894 A ZA 9703894A ZA 973894 A ZA973894 A ZA 973894A ZA 973894 B ZA973894 B ZA 973894B
Authority
ZA
South Africa
Prior art keywords
making same
erythromycins
substituted
substituted erythromycins
making
Prior art date
Application number
ZA9703894A
Other languages
English (en)
Inventor
Yat Sun Or
Richard F Clark
Zhenkun Ma
George Griesgraber
Leping Li
Daniel T Chu
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of ZA973894B publication Critical patent/ZA973894B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
ZA9703894A 1996-05-07 1997-05-06 6-0 substituted erythromycins and method for making same. ZA973894B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US64647796A 1996-05-07 1996-05-07

Publications (1)

Publication Number Publication Date
ZA973894B true ZA973894B (en) 1998-02-23

Family

ID=24593227

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9703894A ZA973894B (en) 1996-05-07 1997-05-06 6-0 substituted erythromycins and method for making same.

Country Status (8)

Country Link
US (1) US6075011A (xx)
EP (1) EP0918783A1 (xx)
JP (2) JP2000509712A (xx)
AR (1) AR007040A1 (xx)
AU (1) AU2340797A (xx)
CA (1) CA2253338C (xx)
WO (1) WO1997042204A1 (xx)
ZA (1) ZA973894B (xx)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998018808A1 (en) * 1996-10-31 1998-05-07 Taisho Pharmaceutical Co., Ltd. Erythromycin a derivatives
JP2000198795A (ja) * 1996-10-31 2000-07-18 Taisho Pharmaceut Co Ltd エリスロマイシンａ誘導体
ZA987689B (en) * 1997-09-02 1999-02-24 Abbott Lab 3-descladinose 6-O substituted erythromycin derivatives
AU1528299A (en) * 1997-12-01 1999-06-16 Abbott Laboratories Chemical synthesis of 6-o-alkyl erythromycin c
DK0941998T3 (da) * 1998-03-03 2004-09-20 Pfizer Prod Inc 3,6-ketalmakrolidantibiotika
CA2349338C (en) * 1998-11-03 2005-12-06 Pfizer Products Inc. Novel macrolide antibiotics
HRP990116B1 (en) * 1999-04-20 2007-10-31 GlaxoSmithKline istra�iva�ki centar Zagreb d.o.o. NOVEL 8a AND 9a- 15-MEMBERED LACTAMES
AP2001002302A0 (en) * 1999-05-24 2001-10-25 Pfizer Prod Inc 13-Methyl erythromycin derivatives.
DK1259923T3 (da) * 2000-02-24 2006-05-01 Abbott Lab Antiinfektionsmiddel, der er anvendeligt mod multilægemiddelresistente bakteriestammer
US6946446B2 (en) 2000-02-24 2005-09-20 Abbott Laboratories Anti-infective agents useful against multidrug-resistant strains of bacteria
US6605707B1 (en) * 2000-03-23 2003-08-12 Abbott Laboratories Process for the preparation of 6-O-propargyl erythromycin derivatives
EP1146051A3 (en) * 2000-04-10 2001-10-31 Pfizer Products Inc. Erythromycin A derivatives
US6455680B1 (en) 2000-12-21 2002-09-24 Abbott Laboratories Methods utilizing aryl thioimines in synthesis of erythromycin derivatives
TWI246515B (en) 2001-05-30 2006-01-01 Abbott Lab An arylation method for the functionalization of O-allyl erythromycin derivatives
AU2002316550A1 (en) 2001-07-03 2003-01-21 Chiron Corporation C12 modified erythromycin macrolides and ketolides having antibacterial activity
US6727229B2 (en) * 2002-08-19 2004-04-27 Enanta Pharmaceuticals, Inc. 11,12-substituted lactone ketolide derivatives having antibacterial activity
ES2552682T3 (es) * 2003-03-10 2015-12-01 Merck Sharp & Dohme Corp. Agentes antibacterianos novedosos
WO2004096823A2 (en) * 2003-04-25 2004-11-11 Chiron Corporation Novel ketolide derivatives
EP1618119A2 (en) * 2003-04-25 2006-01-25 Chiron Corporation Pyridyl substituted ketolide antibiotics
US20040254126A1 (en) * 2003-06-05 2004-12-16 Yao-Ling Qiu 11-12 Bicyclic erythromycin derivatives
US7414030B2 (en) * 2004-01-07 2008-08-19 Enanta Pharmaceuticals, Inc. 6-11 Bicyclic erythromycin derivatives
US7229972B2 (en) * 2004-12-07 2007-06-12 Enanta Pharmaceuticals, Inc. 3,6-Bicyclolides
JP2008522978A (ja) * 2004-12-07 2008-07-03 エナンタ ファーマシューティカルズ インコーポレイテッド ３，６−ビシクロライド
US7291602B2 (en) * 2004-12-13 2007-11-06 Enanta Pharmaceuticals, Inc. 11,12-lactone bicyclolides
UA85937C2 (uk) * 2004-12-21 2009-03-10 Пфайзер Продактс Інк. Макроліди
US7384922B2 (en) * 2005-05-04 2008-06-10 Enanta Pharmaceuticals, Inc. 6-11 bridged oxime erythromycin derivatives
US7547679B2 (en) 2005-05-10 2009-06-16 Glaxosmithkline Istrazivacki Center Zagreb D.O.O Ether linked macrolides useful for the treatment of microbial infections
US7582611B2 (en) 2005-05-24 2009-09-01 Pfizer Inc. Motilide compounds
NZ568763A (en) * 2005-12-08 2010-04-30 Pfizer Method for demethylating the 3'-dimethylamino group of erythromycin compounds
CN101326193B (zh) * 2005-12-08 2011-12-14 辉瑞大药厂 红霉素化合物中3'-二甲基氨基的脱甲基化方法
JPWO2009019868A1 (ja) 2007-08-06 2010-10-28 大正製薬株式会社 １０ａ、１２位架橋型１０ａ−アザライド化合物
WO2009053259A1 (en) * 2007-10-25 2009-04-30 Sandoz Ag Process for the production of telithromycin
US8299035B2 (en) 2008-05-15 2012-10-30 Taisho Pharmaceutucal Co., Ltd. 10a-azalide compound having 4-membered ring structure

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8506380D0 (en) * 1985-03-12 1985-04-11 Beecham Group Plc Chemical compounds
DE3689758T2 (de) * 1985-08-31 1994-08-18 Kitasato Inst Erythromycinderivat und Verfahren zu dessen Herstellung.
KR960000434B1 (ko) * 1986-12-17 1996-01-06 다이쇼 세이야꾸 가부시끼가이샤 에리스로마이신 a유도체 및 그의 제조 방법
JP2782793B2 (ja) * 1988-06-15 1998-08-06 大正製薬株式会社 エリスロマイシンａ誘導体およびその製造方法
IL99995A (en) * 1990-11-21 1997-11-20 Roussel Uclaf Erythromycin derivatives, their preparation and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
EP0918783A1 (en) 1999-06-02
AR007040A1 (es) 1999-10-13
AU2340797A (en) 1997-11-26
JP2000509712A (ja) 2000-08-02
WO1997042204A1 (en) 1997-11-13
JP2002515034A (ja) 2002-05-21
US6075011A (en) 2000-06-13
CA2253338C (en) 2007-05-08
CA2253338A1 (en) 1997-11-13

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