ZA972247B - Combination of enzymes for the destruction of proliferative cells. - Google Patents

Combination of enzymes for the destruction of proliferative cells.

Info

Publication number
ZA972247B
ZA972247B ZA9702247A ZA972247A ZA972247B ZA 972247 B ZA972247 B ZA 972247B ZA 9702247 A ZA9702247 A ZA 9702247A ZA 972247 A ZA972247 A ZA 972247A ZA 972247 B ZA972247 B ZA 972247B
Authority
ZA
South Africa
Prior art keywords
destruction
enzymes
combination
proliferative cells
proliferative
Prior art date
Application number
ZA9702247A
Other languages
English (en)
Inventor
Francis Blanche
Beatrice Cameron
Michel Couder
Joel Crouzet
Original Assignee
Rhone Poulenc Rorer Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer Sa filed Critical Rhone Poulenc Rorer Sa
Publication of ZA972247B publication Critical patent/ZA972247B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86Viral vectors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/45Transferases (2)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/12Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
    • C12N9/1211Thymidine kinase (2.7.1.21)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biotechnology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Virology (AREA)
  • Biophysics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
ZA9702247A 1996-03-15 1997-03-14 Combination of enzymes for the destruction of proliferative cells. ZA972247B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9603267A FR2746016B1 (fr) 1996-03-15 1996-03-15 Combinaisons d'enzymes pour la destruction de cellules proliferatives

Publications (1)

Publication Number Publication Date
ZA972247B true ZA972247B (en) 1997-09-17

Family

ID=9490214

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9702247A ZA972247B (en) 1996-03-15 1997-03-14 Combination of enzymes for the destruction of proliferative cells.

Country Status (15)

Country Link
US (1) US6518062B1 (ko)
EP (1) EP0910654A1 (ko)
JP (1) JP2000507814A (ko)
KR (1) KR20000064581A (ko)
AU (1) AU732432B2 (ko)
BR (1) BR9708194A (ko)
CA (1) CA2248629A1 (ko)
CZ (1) CZ291398A3 (ko)
FR (1) FR2746016B1 (ko)
HU (1) HUP9902320A3 (ko)
IL (1) IL126154A0 (ko)
NO (1) NO984132L (ko)
SK (1) SK124598A3 (ko)
WO (1) WO1997035024A1 (ko)
ZA (1) ZA972247B (ko)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1025212B1 (en) 1997-10-14 2007-09-26 Darwin Molecular Corporation Thymidine kinase mutants and fusion proteins having thymidine kinase and guanylate kinase activities
EP1914304A1 (en) * 1998-10-14 2008-04-23 Darwin Molecular Corporation Thymidine kinase mutants and fusion proteins having thymidine kinase and guanylate kinase activities
GB9924981D0 (en) * 1999-10-21 1999-12-22 Univ Manchester Gene therapy
CA2342040C (en) * 2000-09-21 2012-07-10 Kyowa Hakko Kogyo Co., Ltd. Anaerobic bacterium as a drug for cancer gene therapy
WO2002056022A2 (en) * 2000-11-27 2002-07-18 Minerva Biotechnologies Corp Diagnostics, drug screening and treatment for cancer
ES2364663T3 (es) * 2004-08-12 2011-09-08 Cedars-Sinai Medical Center Terapia génica combinada para el tratamiento de gliomas macroscópicos.
WO2008095027A2 (en) * 2007-01-30 2008-08-07 Cedars-Sinai Medical Center Adenoviral vector comprising herpes simplex virus type 1 thymidine kinase and a transgene for increasing the expression of the transgene
US11746159B2 (en) 2015-02-10 2023-09-05 Minerva Biotechnologies Corporation Humanized anti-MUC1* antibodies
WO2016171529A1 (ko) 2015-04-24 2016-10-27 포항공과대학교 산학협력단 스마트 콘택트 렌즈 및 스마트 안경
KR102303140B1 (ko) 2018-05-30 2021-09-16 이화여자대학교 산학협력단 신규 바이페닐 유도체 화합물 및 이의 용도

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE72122T1 (de) * 1987-04-24 1992-02-15 Wellcome Found Antivirale mischungen.
EP0758387B1 (en) * 1994-05-02 2001-12-19 University of Washington Thymidine kinase mutants
FR2723962B1 (fr) * 1994-08-25 1996-10-31 Univ Paris Curie Hsv1-tk modifiee fonctionnelle
US5856153A (en) * 1994-11-17 1999-01-05 Cayla Suicide genes and new associations of pyrimidine nucleobase and nucleoside analogs with new suicide genes for gene therapy of acquired diseases

Also Published As

Publication number Publication date
WO1997035024A1 (fr) 1997-09-25
SK124598A3 (en) 1999-03-12
FR2746016B1 (fr) 1998-04-17
CA2248629A1 (fr) 1997-09-25
HUP9902320A2 (hu) 1999-10-28
BR9708194A (pt) 1999-07-27
NO984132D0 (no) 1998-09-08
NO984132L (no) 1998-09-08
FR2746016A1 (fr) 1997-09-19
US6518062B1 (en) 2003-02-11
EP0910654A1 (fr) 1999-04-28
KR20000064581A (ko) 2000-11-06
AU732432B2 (en) 2001-04-26
AU2164297A (en) 1997-10-10
HUP9902320A3 (en) 2001-05-28
IL126154A0 (en) 1999-05-09
JP2000507814A (ja) 2000-06-27
CZ291398A3 (cs) 1998-12-16

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